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British Journal of Pharmacology, ISSN 0007-1188, 02/2013, Volume 168, Issue 4, pp. 863 - 879
Background and Purpose Nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor antagonists have been proposed as a novel therapeutic approach to Parkinson's disease... 
NOP antagonist | L‐DOPA | nociceptin/orphanin FQ | reserpine SB‐612111 | Parkinson's disease | 6‐hydroxydopamine | NiK‐21273 | 6-hydroxydopamine | reserpine SB-612111 | L-DOPA | NiK-21273 | GLUTAMATE RELEASE | PHARMACOLOGICAL CHARACTERIZATION | SUBSTANTIA-NIGRA | ARRIVE GUIDELINES | TRANSMISSION | MESSENGER-RNA | IN-VIVO | PHARMACOLOGY & PHARMACY | EXPRESSION | PARKINSONS-DISEASE | Cycloheptanes - pharmacology | Receptors, Opioid - genetics | Antiparkinson Agents - pharmacology | Cricetulus | Calcium - metabolism | Motor Activity - drug effects | Male | Indoles - administration & dosage | Antiparkinson Agents - therapeutic use | Dose-Response Relationship, Drug | Narcotic Antagonists | Muscle, Smooth - drug effects | Transfection | Piperidines - pharmacology | Cycloheptanes - administration & dosage | Reserpine - pharmacology | Behavior, Animal - drug effects | Indoles - pharmacology | Vas Deferens - drug effects | CHO Cells | Parkinsonian Disorders - physiopathology | Cricetinae | Piperidines - administration & dosage | Cycloheptanes - therapeutic use | Rats | Parkinsonian Disorders - chemically induced | Mice, Inbred Strains | Rats, Sprague-Dawley | Rotarod Performance Test | Animals | Muscle Contraction - drug effects | Piperidines - therapeutic use | Indoles - therapeutic use | Antiparkinson Agents - administration & dosage | Mice | Parkinsonian Disorders - prevention & control | Corticosteroids | Analysis | Reserpine | Research Papers | nociceptin | orphanin FQ
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2015, Volume 172, Issue 2, pp. 571 - 582
...), a nociceptin/orphanin FQ peptide (NOP) receptor antagonist, on symptoms of pain and anxiety in rats after SPS exposure, and examined N/OFQ... 
PTSD | nociceptin/orphanin FQ | allodynia | single‐prolonged stress | pain sensitivity | von Frey test | hypocortisolism | nociceptin/orphanin FQ peptide receptor | elevated plus maze | JTC‐801 | single-prolonged stress | JTC-801 | nociceptin | PROTEIN | orphanin FQ | NEUROPATHIC-PAIN | CEREBROSPINAL-FLUID | NERVE INJURY | ORL1 | MESSENGER-RNA | PHARMACOLOGY & PHARMACY | orphanin FQ peptide receptor | PHARMACOLOGICAL EVALUATION | BRAIN | AGONIST | Receptors, Opioid - genetics | Amygdala - drug effects | Stress Disorders, Post-Traumatic - metabolism | Opioid Peptides - cerebrospinal fluid | Periaqueductal Gray - drug effects | Male | Anxiety - drug therapy | Hippocampus - drug effects | Pain - metabolism | Benzamides - therapeutic use | Pain - drug therapy | Stress Disorders, Post-Traumatic - drug therapy | Benzamides - pharmacology | Aminoquinolines - pharmacology | Anxiety - metabolism | Disease Models, Animal | Receptors, Opioid - metabolism | Hyperalgesia - metabolism | Amygdala - metabolism | Hot Temperature | Opioid Peptides - metabolism | Rats, Sprague-Dawley | Periaqueductal Gray - metabolism | Hippocampus - metabolism | Animals | Hyperalgesia - drug therapy | Narcotic Antagonists - therapeutic use | Narcotic Antagonists - pharmacology | Opioid Peptides - blood | Aminoquinolines - therapeutic use | Polyvinylidene fluoride | Peptides | RNA | Gene expression | Post-traumatic stress disorder | Post traumatic stress disorder | Behavior | Anxieties | Rodents | Neuropeptides | Anxiety Disorders | Physical Pain | Animal Models | Opioids | Themed Section | New Pathways to Functional Selectivity
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2014, Volume 34, Issue 39, pp. 12953 - 12962
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 01/2012, Volume 37, Issue 2, pp. 378 - 389
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Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2016, Volume 173, Issue 8, pp. 1286 - 1301
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2008, Volume 107, Issue 6, pp. 1683 - 1696
In this study we investigated whether the recently discovered antagonist of the nociceptin/orphanin FQ (N/OFQ) opioid peptide (NOP) receptor, 1‐[1... 
nociceptin/orphanin FQ | Trap‐101 | microdialysis | l‐DOPA | 6‐hydroxydopamine | NOP receptor knockouts | 6-hydroxydopamine | Nociceptin/orphanin FQ | Microdialysis | Trap-101 | L-DOPA | nociceptin |