International Journal of Neuropsychopharmacology, ISSN 1461-1457, 2012, Volume 15, Issue 4, pp. 531 - 540
Abnormal dopaminergic neurotransmission in the hippocampus may be involved in certain aspects of cognitive dysfunction. In the hippocampus, there is little, if...
Amphetamine | dopamine transporter | microdialysis | rat | cocaine | antidepressant | EXTRACELLULAR DOPAMINE | MEMORY FORMATION | PSYCHIATRY | UPTAKE SITES | NEUROSCIENCES | PREFRONTAL CORTEX | CLINICAL NEUROLOGY | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | IN-VIVO | PHARMACOLOGY & PHARMACY | RAT-BRAIN | NORADRENERGIC NEURONS | UPTAKE INHIBITORS | Rats, Wistar | Norepinephrine Plasma Membrane Transport Proteins - physiology | Male | Hippocampus - drug effects | Idazoxan - pharmacology | Drug Interactions | Time Factors | Wakefulness | Raclopride - pharmacology | Tetrodotoxin - pharmacology | Dopamine - metabolism | Drug Administration Routes | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - pharmacology | Morpholines - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Adrenergic alpha-2 Receptor Antagonists - pharmacology | Cocaine - pharmacology | Hippocampus - metabolism | Animals | Microdialysis | Dopamine Antagonists - pharmacology | Adrenergic Uptake Inhibitors - pharmacology
Amphetamine | dopamine transporter | microdialysis | rat | cocaine | antidepressant | EXTRACELLULAR DOPAMINE | MEMORY FORMATION | PSYCHIATRY | UPTAKE SITES | NEUROSCIENCES | PREFRONTAL CORTEX | CLINICAL NEUROLOGY | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | IN-VIVO | PHARMACOLOGY & PHARMACY | RAT-BRAIN | NORADRENERGIC NEURONS | UPTAKE INHIBITORS | Rats, Wistar | Norepinephrine Plasma Membrane Transport Proteins - physiology | Male | Hippocampus - drug effects | Idazoxan - pharmacology | Drug Interactions | Time Factors | Wakefulness | Raclopride - pharmacology | Tetrodotoxin - pharmacology | Dopamine - metabolism | Drug Administration Routes | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - pharmacology | Morpholines - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Adrenergic alpha-2 Receptor Antagonists - pharmacology | Cocaine - pharmacology | Hippocampus - metabolism | Animals | Microdialysis | Dopamine Antagonists - pharmacology | Adrenergic Uptake Inhibitors - pharmacology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2006, Volume 281, Issue 4, pp. 2012 - 2023
In previous studies examining the structural determinants of antidepressant and substrate recognition by serotonin transporters (SERTs), we identified Tyr-95...
NEUROTRANSMITTER TRANSPORTERS | ACID | SPECIES-SCANNING MUTAGENESIS | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOMAIN-I | CITALOPRAM | ESCITALOPRAM | BINDING-SITE | DOPAMINE TRANSPORTER | EXPRESSION | Citalopram - pharmacology | Immunoprecipitation | Models, Chemical | Species Specificity | Stereoisomerism | Humans | Molecular Sequence Data | Substrate Specificity | Serotonin - chemistry | Clomipramine - pharmacology | Mazindol - pharmacology | LLC-PK1 Cells | Isoleucine - chemistry | Fluoxetine - analogs & derivatives | Antidepressive Agents - pharmacology | Cell Membrane - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - chemistry | Binding Sites | Radiopharmaceuticals - pharmacology | Tyrosine - chemistry | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Cysteine - chemistry | Receptors, Serotonin - chemistry | Cocaine - analogs & derivatives | Blotting, Western | Protein Transport | Cocaine - pharmacology | Animals | Methionine - chemistry | Protein Binding | Adrenergic Uptake Inhibitors - pharmacology | Mice | HeLa Cells | Kinetics | Mutation | Serotonin Uptake Inhibitors - pharmacology | Cadmium - chemistry
NEUROTRANSMITTER TRANSPORTERS | ACID | SPECIES-SCANNING MUTAGENESIS | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOMAIN-I | CITALOPRAM | ESCITALOPRAM | BINDING-SITE | DOPAMINE TRANSPORTER | EXPRESSION | Citalopram - pharmacology | Immunoprecipitation | Models, Chemical | Species Specificity | Stereoisomerism | Humans | Molecular Sequence Data | Substrate Specificity | Serotonin - chemistry | Clomipramine - pharmacology | Mazindol - pharmacology | LLC-PK1 Cells | Isoleucine - chemistry | Fluoxetine - analogs & derivatives | Antidepressive Agents - pharmacology | Cell Membrane - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - chemistry | Binding Sites | Radiopharmaceuticals - pharmacology | Tyrosine - chemistry | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Cysteine - chemistry | Receptors, Serotonin - chemistry | Cocaine - analogs & derivatives | Blotting, Western | Protein Transport | Cocaine - pharmacology | Animals | Methionine - chemistry | Protein Binding | Adrenergic Uptake Inhibitors - pharmacology | Mice | HeLa Cells | Kinetics | Mutation | Serotonin Uptake Inhibitors - pharmacology | Cadmium - chemistry
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 2010, Volume 189, Issue 2, pp. 180 - 185
The rotarod test is widely used to evaluate the motor coordination of rodents, and is especially sensitive in detecting cerebellar dysfunction. However, mice...
Phasic neurotransmission | Dopamine | Parkinson's disease | Rotarod | Motor skill learning | Mice | MPTP | DOPAMINE RELEASE | PARKIN-DEFICIENT MICE | BASAL GANGLIA | BIOCHEMICAL RESEARCH METHODS | SUBSTANTIA-NIGRA | NEUROSCIENCES | IMPLICIT MEMORY | DISEASE | LESIONED RATS | NEURONS | MPTP MOUSE MODEL | STRIATUM | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Dopamine Agonists - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Receptors, Dopamine - metabolism | Mice, Inbred C57BL | Ubiquitin-Protein Ligases - metabolism | Male | Rotation | Mice, Knockout | Rotarod Performance Test | Animals | Apomorphine - pharmacology | Time Factors | Dopamine Agents - pharmacology | Ubiquitin-Protein Ligases - genetics | Motor Skills
Phasic neurotransmission | Dopamine | Parkinson's disease | Rotarod | Motor skill learning | Mice | MPTP | DOPAMINE RELEASE | PARKIN-DEFICIENT MICE | BASAL GANGLIA | BIOCHEMICAL RESEARCH METHODS | SUBSTANTIA-NIGRA | NEUROSCIENCES | IMPLICIT MEMORY | DISEASE | LESIONED RATS | NEURONS | MPTP MOUSE MODEL | STRIATUM | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Dopamine Agonists - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Receptors, Dopamine - metabolism | Mice, Inbred C57BL | Ubiquitin-Protein Ligases - metabolism | Male | Rotation | Mice, Knockout | Rotarod Performance Test | Animals | Apomorphine - pharmacology | Time Factors | Dopamine Agents - pharmacology | Ubiquitin-Protein Ligases - genetics | Motor Skills
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 03/2006, Volume 535, Issue 1-3, pp. 98 - 103
Studies from our laboratory have shown that agonists at sigma and sigma receptors inhibit N-methyl-d-aspartate (NMDA)-stimulated dopamine release from motor...
σ receptor | Dopamine transporter | Protein kinase C | Cocaine | Dopamine release | Dopamine Plasma Membrane Transport Proteins - metabolism | Calcium - metabolism | Maleimides - pharmacology | Male | Receptors, sigma - physiology | Tritium | Receptors, sigma - antagonists & inhibitors | Corpus Striatum - metabolism | N-Methylaspartate - pharmacology | Dose-Response Relationship, Drug | Dopamine - secretion | Piperidines - pharmacology | Protein Kinase C - metabolism | Indoles - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Enzyme Inhibitors - pharmacology | Pentazocine - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Receptors, sigma - agonists | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Cocaine - pharmacology | Pyrroles - pharmacology | Animals | Mesylates - pharmacology | Corpus Striatum - drug effects | In Vitro Techniques | Benzylamines - pharmacology | Spiro Compounds - pharmacology
σ receptor | Dopamine transporter | Protein kinase C | Cocaine | Dopamine release | Dopamine Plasma Membrane Transport Proteins - metabolism | Calcium - metabolism | Maleimides - pharmacology | Male | Receptors, sigma - physiology | Tritium | Receptors, sigma - antagonists & inhibitors | Corpus Striatum - metabolism | N-Methylaspartate - pharmacology | Dose-Response Relationship, Drug | Dopamine - secretion | Piperidines - pharmacology | Protein Kinase C - metabolism | Indoles - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Enzyme Inhibitors - pharmacology | Pentazocine - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Receptors, sigma - agonists | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Cocaine - pharmacology | Pyrroles - pharmacology | Animals | Mesylates - pharmacology | Corpus Striatum - drug effects | In Vitro Techniques | Benzylamines - pharmacology | Spiro Compounds - pharmacology
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2007, Volume 568, Issue 1, pp. 112 - 123
Modafinil is a mild psychostimulant used for the treatment of sleep and arousal-related disorders, and has been considered a pharmacotherapy for cocaine and...
Cocaine | Amphetamine | Dopamine | Modafinil | Nicotinic acetylcholine receptor | Nicotine | nicotine | cocaine | modafinil | amphetamine | MECHANISMS | DRUG DISCRIMINATION | DISCRIMINATIVE-STIMULUS | ABUSE | IN-VIVO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MICE | RAT-BRAIN | dopamine | DOPAMINE UPTAKE | nicotinic acetylcholine receptor | Nomifensine - pharmacology | Central Nervous System Stimulants - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - pharmacology | Rats | Male | Corpus Striatum - metabolism | Rats, Sprague-Dawley | Nicotine - pharmacology | Cocaine - pharmacology | Animals | Corpus Striatum - drug effects | Benzhydryl Compounds - pharmacology | Dopamine - metabolism | Care and treatment | Substance abuse | Cardiac glycosides | Stimulants | Cardiotonic agents | Analysis | Phenols | Nervous system agents | Central nervous system agents
Cocaine | Amphetamine | Dopamine | Modafinil | Nicotinic acetylcholine receptor | Nicotine | nicotine | cocaine | modafinil | amphetamine | MECHANISMS | DRUG DISCRIMINATION | DISCRIMINATIVE-STIMULUS | ABUSE | IN-VIVO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MICE | RAT-BRAIN | dopamine | DOPAMINE UPTAKE | nicotinic acetylcholine receptor | Nomifensine - pharmacology | Central Nervous System Stimulants - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - pharmacology | Rats | Male | Corpus Striatum - metabolism | Rats, Sprague-Dawley | Nicotine - pharmacology | Cocaine - pharmacology | Animals | Corpus Striatum - drug effects | Benzhydryl Compounds - pharmacology | Dopamine - metabolism | Care and treatment | Substance abuse | Cardiac glycosides | Stimulants | Cardiotonic agents | Analysis | Phenols | Nervous system agents | Central nervous system agents
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2004, Volume 498, Issue 1, pp. 143 - 151
We analyzed the ability of the mu opioid peptide receptor ligands morphine and naloxone and several antidepressant drugs that are serotonin (fluoxetine),...
Morphine | Naloxone | Discrimination | Antidepressant drug | Tramadol | 5-HT2C RECEPTORS | tramadol | HUMAN LIVER-MICROSOMES | FLUOXETINE | PREFRONTAL CORTEX | morphine | NUCLEUS-ACCUMBENS | antidepressant drug | NEUROPATHIC PAIN | ANALGESIC TRAMADOL | naloxone | PHARMACOLOGICAL PROFILE | PHARMACOLOGY & PHARMACY | discrimination | BIOCHEMICAL PROFILE | Rats, Wistar | Sodium Chloride - pharmacology | Tramadol - pharmacology | Analgesics, Opioid - pharmacology | Male | Dose-Response Relationship, Drug | Discrimination (Psychology) - drug effects | Antidepressive Agents - pharmacology | Cyclohexanols - pharmacology | Biogenic Monoamines - antagonists & inhibitors | Cyclopropanes - pharmacology | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Morphine - pharmacology | Receptors, Opioid, mu - metabolism | Morpholines - pharmacology | Rats | Receptors, Opioid, mu - antagonists & inhibitors | Drug Synergism | Venlafaxine Hydrochloride | Animals | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Adrenergic Uptake Inhibitors - pharmacology | Conditioning, Operant | Biogenic Monoamines - metabolism | Serotonin Uptake Inhibitors - pharmacology
Morphine | Naloxone | Discrimination | Antidepressant drug | Tramadol | 5-HT2C RECEPTORS | tramadol | HUMAN LIVER-MICROSOMES | FLUOXETINE | PREFRONTAL CORTEX | morphine | NUCLEUS-ACCUMBENS | antidepressant drug | NEUROPATHIC PAIN | ANALGESIC TRAMADOL | naloxone | PHARMACOLOGICAL PROFILE | PHARMACOLOGY & PHARMACY | discrimination | BIOCHEMICAL PROFILE | Rats, Wistar | Sodium Chloride - pharmacology | Tramadol - pharmacology | Analgesics, Opioid - pharmacology | Male | Dose-Response Relationship, Drug | Discrimination (Psychology) - drug effects | Antidepressive Agents - pharmacology | Cyclohexanols - pharmacology | Biogenic Monoamines - antagonists & inhibitors | Cyclopropanes - pharmacology | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Morphine - pharmacology | Receptors, Opioid, mu - metabolism | Morpholines - pharmacology | Rats | Receptors, Opioid, mu - antagonists & inhibitors | Drug Synergism | Venlafaxine Hydrochloride | Animals | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Adrenergic Uptake Inhibitors - pharmacology | Conditioning, Operant | Biogenic Monoamines - metabolism | Serotonin Uptake Inhibitors - pharmacology
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2013, Volume 720, Issue 1-3, pp. 186 - 191
A motivational deficit (the loss of pleasure or interest in previously rewarding stimuli) is one of the core symptoms of major depression, and valid models...
Forced swimming test | Nomifensine | Intracranial self-stimulation | Haloperidol | Motivation | Locomotor activity | DEPRESSION | ANTIDEPRESSANT-LIKE | REUPTAKE INHIBITORS | LOCOMOTOR-ACTIVITY | COCAINE | FORCED SWIM TEST | DOPAMINE TRANSPORTER | REWARD | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | Nomifensine - pharmacology | Depression - physiopathology | Self Stimulation | Dopamine Uptake Inhibitors - pharmacology | Rats, Wistar | Rats | Male | Motivation - drug effects | Depression - drug therapy | Animals | Dopamine Antagonists - pharmacology | Depression - psychology | Running | Adrenergic Uptake Inhibitors - pharmacology | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Swimming | Imipramine - pharmacology | Haloperidol - pharmacology | Imipramine | Airports | Runways | Depression, Mental | Dopamine receptors
Forced swimming test | Nomifensine | Intracranial self-stimulation | Haloperidol | Motivation | Locomotor activity | DEPRESSION | ANTIDEPRESSANT-LIKE | REUPTAKE INHIBITORS | LOCOMOTOR-ACTIVITY | COCAINE | FORCED SWIM TEST | DOPAMINE TRANSPORTER | REWARD | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | Nomifensine - pharmacology | Depression - physiopathology | Self Stimulation | Dopamine Uptake Inhibitors - pharmacology | Rats, Wistar | Rats | Male | Motivation - drug effects | Depression - drug therapy | Animals | Dopamine Antagonists - pharmacology | Depression - psychology | Running | Adrenergic Uptake Inhibitors - pharmacology | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Swimming | Imipramine - pharmacology | Haloperidol - pharmacology | Imipramine | Airports | Runways | Depression, Mental | Dopamine receptors
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2010, Volume 335, Issue 1, pp. 124 - 132
Most life-long drug addiction begins during adolescence. Important structural and functional changes in brain occur during adolescence and developmental...
TRANSPORTER | PERIADOLESCENT | COCAINE | PHARMACOLOGY & PHARMACY | INDUCED LOCOMOTION | SEX-DIFFERENCES | AMPHETAMINE | BRAIN | NUCLEUS-ACCUMBENS | MAZINDOL BINDING | AGE | Brain Chemistry - drug effects | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamines - pharmacology | Electrophysiology | Motor Activity - drug effects | Rats | Male | Methylphenidate - pharmacology | Piperazines - pharmacology | Rats, Sprague-Dawley | Animals | Aging - physiology | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Neostriatum - drug effects | Behavior, Animal - drug effects | Neostriatum - metabolism | Dopamine - metabolism
TRANSPORTER | PERIADOLESCENT | COCAINE | PHARMACOLOGY & PHARMACY | INDUCED LOCOMOTION | SEX-DIFFERENCES | AMPHETAMINE | BRAIN | NUCLEUS-ACCUMBENS | MAZINDOL BINDING | AGE | Brain Chemistry - drug effects | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Amphetamines - pharmacology | Electrophysiology | Motor Activity - drug effects | Rats | Male | Methylphenidate - pharmacology | Piperazines - pharmacology | Rats, Sprague-Dawley | Animals | Aging - physiology | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Neostriatum - drug effects | Behavior, Animal - drug effects | Neostriatum - metabolism | Dopamine - metabolism
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2004, Volume 504, Issue 3, pp. 207 - 211
The effects of dopamine re-uptake inhibitors, bupropion and nomifensine on immobility in the forced swimming test were studied in mice. Bupropion and...
Antidepressant | Forced swimming test | Nomifensine | Bupropion | Dopamine D2 receptor | Dopamine D1 receptor | 5-HT2 RECEPTOR | DEPRESSION | ANTAGONIST | BEHAVIORAL DESPAIR | antidepressant | forced swimming test | nomifensine | dopamine D2 receptor | IMIPRAMINE | PHARMACOLOGY & PHARMACY | MICE | bupropion | dopamine D1 receptor | Dopamine Uptake Inhibitors - antagonists & inhibitors | Nomifensine - pharmacology | Sulpiride - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Receptors, Dopamine D1 - drug effects | Motor Activity - drug effects | Male | Benzazepines - pharmacology | Dose-Response Relationship, Drug | Nomifensine - antagonists & inhibitors | Receptors, Dopamine - drug effects | Bupropion - antagonists & inhibitors | Animals | Drug Interactions | Swimming - psychology | Dopamine Antagonists - pharmacology | Receptors, Dopamine D2 - drug effects | Depression - psychology | Bupropion - pharmacology | Mice
Antidepressant | Forced swimming test | Nomifensine | Bupropion | Dopamine D2 receptor | Dopamine D1 receptor | 5-HT2 RECEPTOR | DEPRESSION | ANTAGONIST | BEHAVIORAL DESPAIR | antidepressant | forced swimming test | nomifensine | dopamine D2 receptor | IMIPRAMINE | PHARMACOLOGY & PHARMACY | MICE | bupropion | dopamine D1 receptor | Dopamine Uptake Inhibitors - antagonists & inhibitors | Nomifensine - pharmacology | Sulpiride - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Receptors, Dopamine D1 - drug effects | Motor Activity - drug effects | Male | Benzazepines - pharmacology | Dose-Response Relationship, Drug | Nomifensine - antagonists & inhibitors | Receptors, Dopamine - drug effects | Bupropion - antagonists & inhibitors | Animals | Drug Interactions | Swimming - psychology | Dopamine Antagonists - pharmacology | Receptors, Dopamine D2 - drug effects | Depression - psychology | Bupropion - pharmacology | Mice
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 03/2008, Volume 75, Issue 6, pp. 1411 - 1415
The mechanisms of interaction between lobeline and the dopamine transporter (DAT) or the vesicular monoamine transporter (VMAT-2) are not clear. The goal of...
Dopamine transporter | Lobeline | Dopamine | Vesicular monoamine transporter | Methamphetamine | vesicular monoamine transporter | SYNAPTIC VESICLES | TRANSPORTER | RATS | MECHANISMS | VESICULAR MONOAMINE | dopamine transporter | methamphetamine | lobeline | PHARMACOLOGY & PHARMACY | MICE | dopamine | NICOTINIC DRUGS | AMPHETAMINE | MODULATION | Methamphetamine - pharmacology | Cell Line | Dopamine Plasma Membrane Transport Proteins - metabolism | Nomifensine - pharmacology | Vesicular Monoamine Transport Proteins - metabolism | Dopamine Uptake Inhibitors - pharmacology | Humans | Lobeline - pharmacology | Dopamine - pharmacology | Vesicular Monoamine Transport Proteins - antagonists & inhibitors | Amphetamine-Related Disorders - drug therapy | Cocaine - analogs & derivatives | Dopamine Plasma Membrane Transport Proteins - antagonists & inhibitors | Cocaine - pharmacology | Dopamine Agents - pharmacology | Reserpine - pharmacology | Dopamine - metabolism | Phenols | Corticosteroids | Reserpine | Index Medicus
Dopamine transporter | Lobeline | Dopamine | Vesicular monoamine transporter | Methamphetamine | vesicular monoamine transporter | SYNAPTIC VESICLES | TRANSPORTER | RATS | MECHANISMS | VESICULAR MONOAMINE | dopamine transporter | methamphetamine | lobeline | PHARMACOLOGY & PHARMACY | MICE | dopamine | NICOTINIC DRUGS | AMPHETAMINE | MODULATION | Methamphetamine - pharmacology | Cell Line | Dopamine Plasma Membrane Transport Proteins - metabolism | Nomifensine - pharmacology | Vesicular Monoamine Transport Proteins - metabolism | Dopamine Uptake Inhibitors - pharmacology | Humans | Lobeline - pharmacology | Dopamine - pharmacology | Vesicular Monoamine Transport Proteins - antagonists & inhibitors | Amphetamine-Related Disorders - drug therapy | Cocaine - analogs & derivatives | Dopamine Plasma Membrane Transport Proteins - antagonists & inhibitors | Cocaine - pharmacology | Dopamine Agents - pharmacology | Reserpine - pharmacology | Dopamine - metabolism | Phenols | Corticosteroids | Reserpine | Index Medicus
Journal Article
Brain Research, ISSN 0006-8993, 2005, Volume 1061, Issue 2, pp. 88 - 96
Dopamine signaling is an important component of many goal-directed behaviors, such as feeding. Acute disruption of dopamine signaling using pharmacological...
Nomifensine | Striatum | Knockout mice | Amphetamine | Dopamine | Food intake | Monoamine | Canine adenovirus | Apomorphine | CAUDATE-PUTAMEN | knockout mice | TYROSINE-HYDROXYLASE | FOOD-INTAKE | BEHAVIOR | amphetamine | AMPHETAMINE ANOREXIA | RATS | nomifensine | DEFICIENT MICE | NEUROSCIENCES | NUCLEUS-ACCUMBENS | apomorphine | striatum | canine adenovirus | monoamine | RECEPTORS | dopamine | CANINE ADENOVIRUS VECTORS | food intake | Neostriatum - enzymology | Tyrosine 3-Monooxygenase - metabolism | Injections, Intraventricular | Dopamine - genetics | Eating - physiology | Neostriatum - physiology | Dopamine - deficiency | Apomorphine - pharmacology | Neostriatum - drug effects | Dopamine - physiology | Dopamine Agents - pharmacology | Mesencephalon - drug effects | Hypothalamus - drug effects | Dopamine Agonists - pharmacology | Levodopa - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Mesencephalon - enzymology | Mice, Inbred C57BL | Amphetamine - pharmacology | Signal Transduction - genetics | Feeding Behavior - physiology | Feeding Behavior - drug effects | Mice, Knockout | Eating - drug effects | Animals | Signal Transduction - drug effects | Hypothalamus - enzymology | Signal Transduction - physiology | Mice | Stimulants | Neurons | Phenols | Hydroxylases | Humic acid
Nomifensine | Striatum | Knockout mice | Amphetamine | Dopamine | Food intake | Monoamine | Canine adenovirus | Apomorphine | CAUDATE-PUTAMEN | knockout mice | TYROSINE-HYDROXYLASE | FOOD-INTAKE | BEHAVIOR | amphetamine | AMPHETAMINE ANOREXIA | RATS | nomifensine | DEFICIENT MICE | NEUROSCIENCES | NUCLEUS-ACCUMBENS | apomorphine | striatum | canine adenovirus | monoamine | RECEPTORS | dopamine | CANINE ADENOVIRUS VECTORS | food intake | Neostriatum - enzymology | Tyrosine 3-Monooxygenase - metabolism | Injections, Intraventricular | Dopamine - genetics | Eating - physiology | Neostriatum - physiology | Dopamine - deficiency | Apomorphine - pharmacology | Neostriatum - drug effects | Dopamine - physiology | Dopamine Agents - pharmacology | Mesencephalon - drug effects | Hypothalamus - drug effects | Dopamine Agonists - pharmacology | Levodopa - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Mesencephalon - enzymology | Mice, Inbred C57BL | Amphetamine - pharmacology | Signal Transduction - genetics | Feeding Behavior - physiology | Feeding Behavior - drug effects | Mice, Knockout | Eating - drug effects | Animals | Signal Transduction - drug effects | Hypothalamus - enzymology | Signal Transduction - physiology | Mice | Stimulants | Neurons | Phenols | Hydroxylases | Humic acid
Journal Article
Neuropharmacology, ISSN 0028-3908, 2007, Volume 52, Issue 2, pp. 626 - 633
Modafinil is a well-tolerated medication for excessive sleepiness, attention-deficit disorder, cocaine dependence and as an adjunct to antidepressants with low...
Dopamine | Reward | Ventral tegmental area | Whole-cell patch clamp | Arousal | reward | INDUCED WAKEFULNESS | PROMOTING AGENT MODAFINIL | GLUTAMATE RELEASE | CONSCIOUS RAT | COCAINE | SUBSTANTIA-NIGRA | NEUROSCIENCES | IN-VITRO | ventral tegmental area | DRUG MODAFINIL | whole-cell patch clamp | PHARMACOLOGY & PHARMACY | dopamine | AMPHETAMINE | arousal | Nomifensine - pharmacology | Sulpiride - pharmacology | Central Nervous System Stimulants - pharmacology | Electric Stimulation | Mesencephalon - cytology | Dopamine Uptake Inhibitors - pharmacology | Rats, Wistar | Rats | Male | Gene Expression Regulation - drug effects | Animals | Drug Interactions | Dopamine Antagonists - pharmacology | Isoenzymes - metabolism | Glutamate Decarboxylase - metabolism | Benzhydryl Compounds - pharmacology | In Vitro Techniques | Neurons - drug effects | Dose-Response Relationship, Radiation | Neural Inhibition - drug effects | Action Potentials - drug effects | Dopamine - metabolism | Modafinil | Neurons | Nomifensine | Central Nervous System Stimulants | Neural Inhibition | Mesencephalon | Benzhydryl Compounds | Isoenzymes | Gene Expression Regulation | Glutamate Decarboxylase | Sulpiride | Tissues and Organs | Action Potentials | Life Sciences | Human health and pathology | Dopamine Antagonists | Dopamine Uptake Inhibitors
Dopamine | Reward | Ventral tegmental area | Whole-cell patch clamp | Arousal | reward | INDUCED WAKEFULNESS | PROMOTING AGENT MODAFINIL | GLUTAMATE RELEASE | CONSCIOUS RAT | COCAINE | SUBSTANTIA-NIGRA | NEUROSCIENCES | IN-VITRO | ventral tegmental area | DRUG MODAFINIL | whole-cell patch clamp | PHARMACOLOGY & PHARMACY | dopamine | AMPHETAMINE | arousal | Nomifensine - pharmacology | Sulpiride - pharmacology | Central Nervous System Stimulants - pharmacology | Electric Stimulation | Mesencephalon - cytology | Dopamine Uptake Inhibitors - pharmacology | Rats, Wistar | Rats | Male | Gene Expression Regulation - drug effects | Animals | Drug Interactions | Dopamine Antagonists - pharmacology | Isoenzymes - metabolism | Glutamate Decarboxylase - metabolism | Benzhydryl Compounds - pharmacology | In Vitro Techniques | Neurons - drug effects | Dose-Response Relationship, Radiation | Neural Inhibition - drug effects | Action Potentials - drug effects | Dopamine - metabolism | Modafinil | Neurons | Nomifensine | Central Nervous System Stimulants | Neural Inhibition | Mesencephalon | Benzhydryl Compounds | Isoenzymes | Gene Expression Regulation | Glutamate Decarboxylase | Sulpiride | Tissues and Organs | Action Potentials | Life Sciences | Human health and pathology | Dopamine Antagonists | Dopamine Uptake Inhibitors
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2006, Volume 78, Issue 18, pp. 6347 - 6355
Novel, yet simple detection techniques of drug effect, including the effect of a vesicular monoamine transporter inhibitor (reserpine), a dopamine precursor...
CHEMISTRY, ANALYTICAL | STIMULATION | NEURONAL NETWORKS | EXOCYTOSIS | BIOSENSORS | VESICULAR MONOAMINE TRANSPORTER | QUANTAL SIZE | TYROSINE-HYDROXYLASE | PEROXYNITRITE | BRAIN-SLICES | NITRATION | Microarray Analysis - methods | Drug Evaluation, Preclinical - methods | Levodopa - pharmacology | Microelectrodes | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Microarray Analysis - instrumentation | Rats | PC12 Cells | Animals | Dopamine - secretion | Dopamine Agents - pharmacology | Drug Evaluation, Preclinical - instrumentation | Reserpine - pharmacology | Antipsychotic Agents - pharmacology | Drugs | Product/Service Evaluations | Dopamine | Analysis | Biochips
CHEMISTRY, ANALYTICAL | STIMULATION | NEURONAL NETWORKS | EXOCYTOSIS | BIOSENSORS | VESICULAR MONOAMINE TRANSPORTER | QUANTAL SIZE | TYROSINE-HYDROXYLASE | PEROXYNITRITE | BRAIN-SLICES | NITRATION | Microarray Analysis - methods | Drug Evaluation, Preclinical - methods | Levodopa - pharmacology | Microelectrodes | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Microarray Analysis - instrumentation | Rats | PC12 Cells | Animals | Dopamine - secretion | Dopamine Agents - pharmacology | Drug Evaluation, Preclinical - instrumentation | Reserpine - pharmacology | Antipsychotic Agents - pharmacology | Drugs | Product/Service Evaluations | Dopamine | Analysis | Biochips
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 02/2006, Volume 23, Issue 4, pp. 1005 - 1014
The precise mechanism whereby continuous high‐frequency electrical stimulation of the subthalamic nucleus ameliorates motor symptoms of Parkinson's disease is...
amperometry | substantia nigra | high frequency stimulation | electrophysiology | deep brain stimulation | Amperometry | Electrophysiology | Deep brain stimulation | High frequency stimulation | Substantia nigra | NEURON ACTIVITY | GLOBUS-PALLIDUS | HIGH-FREQUENCY STIMULATION | RELEASE | SUBSTANTIA-NIGRA | NEUROSCIENCES | EXTRACELLULAR GLUTAMATE | TRANSMISSION | METABOLISM | IN-VIVO | DEEP BRAIN-STIMULATION | Tyrosine 3-Monooxygenase - metabolism | Rats, Wistar | Corpus Striatum - radiation effects | Male | Corpus Striatum - metabolism | Behavior, Animal | Desipramine - pharmacology | Drug Interactions | Action Potentials - radiation effects | Female | Electric Stimulation - methods | Dopamine - metabolism | Disease Models, Animal | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Parkinson Disease - physiopathology | Rats, Sprague-Dawley | Action Potentials - physiology | Immunohistochemistry - methods | Subthalamic Nucleus - radiation effects | Animals | In Vitro Techniques | Serotonin Uptake Inhibitors - pharmacology | Dose-Response Relationship, Radiation | Physiological aspects | Parkinson's disease
amperometry | substantia nigra | high frequency stimulation | electrophysiology | deep brain stimulation | Amperometry | Electrophysiology | Deep brain stimulation | High frequency stimulation | Substantia nigra | NEURON ACTIVITY | GLOBUS-PALLIDUS | HIGH-FREQUENCY STIMULATION | RELEASE | SUBSTANTIA-NIGRA | NEUROSCIENCES | EXTRACELLULAR GLUTAMATE | TRANSMISSION | METABOLISM | IN-VIVO | DEEP BRAIN-STIMULATION | Tyrosine 3-Monooxygenase - metabolism | Rats, Wistar | Corpus Striatum - radiation effects | Male | Corpus Striatum - metabolism | Behavior, Animal | Desipramine - pharmacology | Drug Interactions | Action Potentials - radiation effects | Female | Electric Stimulation - methods | Dopamine - metabolism | Disease Models, Animal | Fluoxetine - pharmacology | Nomifensine - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Parkinson Disease - physiopathology | Rats, Sprague-Dawley | Action Potentials - physiology | Immunohistochemistry - methods | Subthalamic Nucleus - radiation effects | Animals | In Vitro Techniques | Serotonin Uptake Inhibitors - pharmacology | Dose-Response Relationship, Radiation | Physiological aspects | Parkinson's disease
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2018, Volume 819, pp. 242 - 247
Diclofensine, diphenidine, and methoxphenidine are new psychoactive substances (NPSs) that recently appeared on the illicit drug market. Pharmacological...
Monoamine | Methoxphenidine | New psychoactive substance | Diclofensine | Diphenidine | DESIGNER CATHINONES | SEROTONIN TRANSPORTER | RECEPTOR INTERACTION PROFILES | RO 8-4650 | POTENT INHIBITOR | IN-VITRO | DOPAMINE D-3 | NOMIFENSINE | PHARMACOLOGICAL PROFILE | RECREATIONAL USE | PHARMACOLOGY & PHARMACY | NIH 3T3 Cells | Animals | Isoquinolines - pharmacology | Piperidines - pharmacology | Psychotropic Drugs - pharmacology | Membrane Transport Proteins - metabolism | Mice | Biogenic Monoamines - metabolism | Index Medicus
Monoamine | Methoxphenidine | New psychoactive substance | Diclofensine | Diphenidine | DESIGNER CATHINONES | SEROTONIN TRANSPORTER | RECEPTOR INTERACTION PROFILES | RO 8-4650 | POTENT INHIBITOR | IN-VITRO | DOPAMINE D-3 | NOMIFENSINE | PHARMACOLOGICAL PROFILE | RECREATIONAL USE | PHARMACOLOGY & PHARMACY | NIH 3T3 Cells | Animals | Isoquinolines - pharmacology | Piperidines - pharmacology | Psychotropic Drugs - pharmacology | Membrane Transport Proteins - metabolism | Mice | Biogenic Monoamines - metabolism | Index Medicus
Journal Article