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Molecular systems biology, ISSN 1744-4292, 2017, Volume 13, Issue 3, pp. 916 - n/a
To elucidate the molecular mechanisms underlying non-alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis... 
serine | NAFLD | personalized genome‐scale metabolic modeling | glutathione | personalized genome-scale metabolic modeling | FATTY LIVER-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSCLE | DRUG TARGETS | CANCER | AMINO-ACID-METABOLISM | HEPATOCELLULAR-CARCINOMA | INSULIN-RESISTANCE | ADIPOSE-TISSUE | GENOME-SCALE | REVEALS | Glycine - blood | Liver - enzymology | Non-alcoholic Fatty Liver Disease - genetics | Glutathione - metabolism | Serine - blood | Humans | Liver - metabolism | Middle Aged | Male | Non-alcoholic Fatty Liver Disease - metabolism | Patient-Specific Modeling | Metabolomics - methods | Gene Expression Regulation, Enzymologic | Serine - administration & dosage | Animals | Lipoproteins - metabolism | Female | Mice | Non-alcoholic Fatty Liver Disease - diet therapy | Genome | NAD - metabolism | Serine - therapeutic use | Disease Models, Animal | Genomes | Metabolites | Metabolism | Liver | Rodents | Serine | Lipids | Biosynthesis | Glycine | Body mass index | Fatty liver | Precursors | Supplementation | Glutathione | Level (quantity) | Liver diseases | Fasting | Demand analysis | Dietary supplements | Triglycerides | Fluxes | Apolipoproteins | Gene expression | Cholesterol | Steatosis | NAD | Molecular modelling | Insulin resistance | Plasma levels | Laboratory animals | Life Sciences | Biochemistry, Molecular Biology | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 3/2014, Volume 32, Issue 1, pp. 25 - 50
CD47 is a broadly expressed membrane protein that interacts with the myeloid inhibitory immunoreceptor SIRPα (also termed CD172a or SHPS-1). SIRPα is the... 
phagocytosis | SIRPα | cancer | paired receptor | CD47 | inflammation | Paired receptor | Inflammation | Phagocytosis | Cancer | COLLAGEN-INDUCED ARTHRITIS | TYROSINE-PHOSPHATASE SUBSTRATE-1 | DENDRITIC CELLS | AUTOIMMUNE HEMOLYTIC-ANEMIA | IMMUNOLOGY | INTEGRIN-ASSOCIATED PROTEIN | INNATE IMMUNE ACTIVATION | HEMATOPOIETIC STEM-CELLS | SIRP alpha | NON-HODGKIN-LYMPHOMA | RED-BLOOD-CELLS | HUMAN T-CELL | Multigene Family | Receptors, Immunologic - chemistry | Neoplasms - etiology | Dendritic Cells - immunology | Humans | Hematologic Diseases - drug therapy | Autoimmune Diseases - etiology | Molecular Targeted Therapy | Immunological Synapses - metabolism | T-Lymphocytes - metabolism | Protein Binding - drug effects | Antigens, Differentiation - metabolism | Autoimmune Diseases - drug therapy | Dendritic Cells - metabolism | CD47 Antigen - genetics | Phagocytosis - drug effects | Signal Transduction | CD47 Antigen - chemistry | Phagocytosis - immunology | CD47 Antigen - metabolism | Neoplasms - drug therapy | Animals | Antigens, Differentiation - chemistry | Hematologic Diseases - etiology | Immunological Synapses - immunology | T-Lymphocytes - immunology | Antigens, Differentiation - genetics | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Physiological aspects | Research | Oncology, Experimental | Blood proteins
Journal Article