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1. Full Text Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial
by Schwimmer, Jeffrey B and Ugalde-Nicalo, Patricia and Welsh, Jean A and Angeles, Jorge E and Cordero, Maria and Harlow, Kathryn E and Alazraki, Adina and Durelle, Janis and Knight-Scott, Jack and Newton, Kimberly P and Cleeton, Rebecca and Knott, Cynthia and Konomi, Juna and Middleton, Michael S and Travers, Curtis and Sirlin, Claude B and Hernandez, Albert and Sekkarie, Ahlia and McCracken, Courtney and Vos, Miriam B
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 01/2019, Volume 321, Issue 3, pp. 256 - 265
IMPORTANCE Pediatric guidelines for the management of nonalcoholic fatty liver disease (NAFLD) recommend a healthy diet as treatment. Reduction of sugary foods... 
DIAGNOSIS | FRACTION | MEDICINE, GENERAL & INTERNAL | PRACTICE GUIDELINE | FRUCTOSE | MANAGEMENT | DE-NOVO LIPOGENESIS | STEATOSIS | ADULTS | ASSOCIATION | CHILDREN | Body Mass Index | Liver Function Tests | Blood Glucose - analysis | Humans | Hispanic Americans | Male | Non-alcoholic Fatty Liver Disease - ethnology | Treatment Outcome | Dietary Sugars | Non-alcoholic Fatty Liver Disease - blood | Weight Loss | Lipids - blood | Adolescent | Non-alcoholic Fatty Liver Disease - diet therapy | Child | Diet, Carbohydrate-Restricted | Control | Usage | Liver diseases | Diet | Magnetic resonance imaging | Teenage boys | Health aspects | Intervention | Liver | Proton density (concentration) | Medical services | Research facilities | Clinical trials | Randomization | Fatty liver | Teenagers | Beverages | Meals | Sugar | Sugars | Food | Fruit juices | Alanine | Nutrient deficiency | Statistical analysis | Medical treatment | Telephone calls | Hypoglycemia | Disease control | Calories | Steatosis | Hypocaloric diet | Alanine transaminase | Index Medicus | Abridged Index Medicus | Preliminary Communication | Research
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2. Full Text Mediterranean diet and non-alcoholic fatty liver disease. The need of extended and comprehensive interventions
by Trovato, Francesca M and Catalano, Daniela and Martines, G. Fabio and Pace, Patrizia and Trovato, Guglielmo M
Clinical Nutrition, ISSN 0261-5614, 02/2015, Volume 34, Issue 1, pp. 86 - 88
Background & aims: Non-alcoholic fatty liver disease (NAFLD) is mostly related to increased BMI and sedentary life, even if it not directly attributable only... 
Obesity | Insulin resistance | NAFLD | Physical activity | Mediterranean diet | POPULATION | RISK | ADHERENCE | EXERCISE | INDIVIDUALS | NUTRITION & DIETETICS | STEATOSIS | PHYSICAL-ACTIVITY | NUTRITIONAL INTERVENTION | BODY | Body Mass Index | Life Style | Diet, Mediterranean | Obesity - complications | Humans | Middle Aged | Insulin Resistance | Non-alcoholic Fatty Liver Disease - etiology | Male | Exercise | Adult | Female | Non-alcoholic Fatty Liver Disease - diet therapy | Index Medicus
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3. Full Text Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis
by Lee, Joseph J and Lambert, Jennifer E and Hovhannisyan, Yelena and Ramos-Roman, Maria A and Trombold, Justin R and Wagner, David A and Parks, Elizabeth J
American Journal of Clinical Nutrition, ISSN 0002-9165, 01/2015, Volume 101, Issue 1, pp. 34 - 43
Background: Biochemical evidence has linked the coordinate control of fatty acid (FA) synthesis with the activity of stearoyl-CoA desaturase-1 (SCD1). The... 
VLDL triacylglycerol | Biomarker | Stearoyl-CoA desaturase | Palmitoleic fatty acid | Lipogenesis | METABOLIC SYNDROME | OBESE SUBJECTS | DE-NOVO LIPOGENESIS | MESSENGER-RNA EXPRESSION | HIGH-CARBOHYDRATE DIET | lipogenesis | NONALCOHOLIC STEATOHEPATITIS | biomarker | TISSUE INSULIN-RESISTANCE | NUTRITION & DIETETICS | stearoyl-CoA desaturase | IN-VIVO | palmitoleic fatty acid | ADIPOSE-TISSUE | Palmitic Acid - metabolism | Up-Regulation | Liver - enzymology | Humans | Non-alcoholic Fatty Liver Disease - etiology | Male | Non-alcoholic Fatty Liver Disease - blood | Palmitic Acid - blood | Adiposity | Fatty Acids, Monounsaturated - metabolism | Adult | Fatty Acids, Monounsaturated - blood | Fatty Acids, Nonesterified - blood | Female | Biomarkers - metabolism | Body Mass Index | Cross-Sectional Studies | Liver - metabolism | Insulin Resistance | Non-alcoholic Fatty Liver Disease - metabolism | Biomarkers - blood | Overweight - physiopathology | Triglycerides - metabolism | Algorithms | Deuterium Oxide - metabolism | Lipoproteins, VLDL - blood | Diet, Fat-Restricted | Lipoproteins, VLDL - metabolism | Triglycerides - blood | Stearoyl-CoA Desaturase - metabolism | Non-alcoholic Fatty Liver Disease - diet therapy | Care and treatment | Monounsaturated fatty acids | Liver diseases | Analysis | Low density lipoproteins | Physiological aspects | Triglycerides | Health aspects | Lipoproteins | Biomarkers | Biochemistry | Biosynthesis | Mass spectrometry | Chromatography | Index Medicus | Abridged Index Medicus
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4. Full Text Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr -/- mice
by Lytle, Kelli A and Wong, Carmen P and Jump, Donald B
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0173376 - e0173376
Background Nonalcoholic fatty liver disease (NAFLD) is a major public health concern in western societies. Nonalcoholic steatohepatitis (NASH), the progressive... 
METABOLIC SYNDROME | HEPATIC INFLAMMATION | PRACTICE GUIDELINE | AMERICAN ASSOCIATION | N-3 | FATTY LIVER-DISEASE | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE RECEPTORS | GENE-EXPRESSION | WEIGHT-LOSS | NATURAL-HISTORY | Osteopontin - genetics | Thrombospondins - genetics | Interleukin 1 Receptor Antagonist Protein - genetics | Male | Osteopontin - metabolism | Growth Differentiation Factor 15 - genetics | Collagen Type I - genetics | Interleukin 1 Receptor Antagonist Protein - metabolism | Dietary Fats - administration & dosage | Receptors, LDL - deficiency | Diet, Western | Extracellular Matrix Proteins - metabolism | Disease Models, Animal | Receptors, LDL - genetics | Collagen Type I - metabolism | Non-alcoholic Fatty Liver Disease - genetics | Extracellular Matrix Proteins - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Non-alcoholic Fatty Liver Disease - metabolism | Olive Oil - administration & dosage | Non-alcoholic Fatty Liver Disease - physiopathology | Docosahexaenoic Acids - administration & dosage | Disease Progression | Mice, Knockout | Animals | Protein-Lysine 6-Oxidase - metabolism | Mice | Protein-Lysine 6-Oxidase - genetics | Non-alcoholic Fatty Liver Disease - diet therapy | Growth Differentiation Factor 15 - metabolism | Thrombospondins - metabolism | Oxidative stress | Regulatory agencies | Collagen (type I) | Polyunsaturated fatty acids | Syngeneic grafts | Liver | Dyslipidemia | Staining | Hepatocellular carcinoma | Docosahexaenoic acid | Low fat | Risk factors | Liver cancer | Hyperglycemia | Fatty liver | Allografts | Rodents | Interleukin 1 | Remission | Lipoprotein (low density) receptors | Public health | Obesity | Liver diseases | Mortality | Health risks | Dietary supplements | Transplants | Olive oil | Gene expression | Steatosis | Cirrhosis | Diet | Liquid oxygen | Collagen | Fibrosis | Low fat diet | Metabolic disorders | Liver transplantation | Index Medicus
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5. Full Text Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis
by Linden, Melissa A and Sheldon, Ryan D and Meers, Grace M and Ortinau, Laura C and Morris, E. Matthew and Booth, Frank W and Kanaley, Jill A and Vieira‐Potter, Victoria J and Sowers, James R and Ibdah, Jamal A and Thyfault, John P and Laughlin, M. Harold and Rector, R. Scott
The Journal of Physiology, ISSN 0022-3751, 09/2016, Volume 594, Issue 18, pp. 5271 - 5284
Physiologically relevant rodent models of non‐alcoholic steatohepatitis (NASH) that resemble the human condition are limited. Exercise training and energy... 
MACROPHAGE INFILTRATION | SKELETAL-MUSCLE | MATRIX METALLOPROTEINASES | METABOLIC SYNDROME | PHYSIOLOGY | HEPATIC STELLATE CELLS | OLETF RATS | CALORIC RESTRICTION | WEIGHT-LOSS | PHYSICAL-ACTIVITY | CELLULAR SENESCENCE | NEUROSCIENCES | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Caloric Restriction | Diet, High-Fat - adverse effects | Male | RNA, Messenger - metabolism | Antigens, CD - genetics | Matrix Metalloproteinase 9 - metabolism | Liver Cirrhosis - metabolism | Liver Cirrhosis - diet therapy | Cytokines - genetics | Physical Conditioning, Animal | Matrix Metalloproteinase 2 - metabolism | Liver - metabolism | Non-alcoholic Fatty Liver Disease - therapy | Liver Cirrhosis - therapy | Non-alcoholic Fatty Liver Disease - metabolism | Diet, Western - adverse effects | Antigens, Differentiation, Myelomonocytic - genetics | Rats, Inbred OLETF | Animals | Liver Cirrhosis - pathology | Dietary Sucrose - adverse effects | Non-alcoholic Fatty Liver Disease - diet therapy | Cholesterol, Dietary - adverse effects | Fatty liver | Exercise | RNA | Collagen | Analysis | Fibrosis | Bone morphogenetic proteins | Muscle proteins | Index Medicus | Integrative | Research Paper | Exercise Physiology | Liver
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6. Full Text Vitamin E has a beneficial effect on nonalcoholic fatty liver disease: A meta-analysis of randomized controlled trials
by Sato, Ken, M.D., Ph.D and Gosho, Masahiko, Ph.D and Yamamoto, Takaya, M.D and Kobayashi, Yuji, M.D., Ph.D and Ishii, Norimitsu, M.D and Ohashi, Tomohiko, M.D., Ph.D and Nakade, Yukiomi, M.D., Ph.D and Ito, Kiyoaki, M.D., Ph.D and Fukuzawa, Yoshitaka, M.D., Ph.D and Yoneda, Masashi, M.D., Ph.D
Nutrition, ISSN 0899-9007, 2015, Volume 31, Issue 7, pp. 923 - 930
Abstract Objectives Vitamin E is often used in the treatment of nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH);... 
Gastroenterology and Hepatology | α-Tocopherol | NAFLD | Nonalcoholic steatohepatitis | NASH | Vitamin E | Meta-analysis | LIFE-STYLE INTERVENTION | DIAGNOSIS | PRACTICE GUIDELINE | LIPID-PEROXIDATION | AMERICAN-GASTROENTEROLOGICAL-ASSOCIATION | alpha-Tocopherol | CHILDREN | ALL-CAUSE MORTALITY | E SUPPLEMENTATION | NUTRITION & DIETETICS | PIOGLITAZONE | STEATOHEPATITIS | Non-alcoholic Fatty Liver Disease - pathology | Fatty Liver - diet therapy | Liver - pathology | Liver - enzymology | Humans | Hepatocytes - pathology | Treatment Outcome | Alanine Transaminase - blood | Randomized Controlled Trials as Topic | Inflammation - diet therapy | Non-alcoholic Fatty Liver Disease - blood | Antioxidants - therapeutic use | Aspartate Aminotransferases - blood | Liver - drug effects | Vitamin E - therapeutic use | Non-alcoholic Fatty Liver Disease - diet therapy | Alkaline Phosphatase - blood | Fibrosis - diet therapy | Hepatocytes - drug effects | Analysis | Fatty liver | Antioxidants | Studies | Confidence intervals | Liver diseases | Bias | Mortality | Clinical trials | Histology | Liver cirrhosis | Index Medicus
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7. Full Text A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): Study protocol
by Papamiltiadous, Elena S and Roberts, Stuart K and Nicoll, Amanda J and Ryan, Marno C and Itsiopoulos, Catherine and Salim, Agus and Tierney, Audrey C
BMC Gastroenterology, ISSN 1471-230X, 02/2016, Volume 16, Issue 1, pp. 14 - 14
Background: Non-alcoholic fatty liver disease, the most prevalent liver disease in developed countries, remains difficult to manage with no proven safe and... 
Insulin resistance | Fatty liver | Non-alcoholic fatty liver disease | Mediterranean diet | METABOLIC SYNDROME | METAANALYSIS | STEATOSIS | WEIGHT-LOSS | MARKERS | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | Complications and side effects | Usage | Care and treatment | Clinical trials | Nuclear magnetic resonance spectroscopy | Research | Index Medicus
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8. Full Text The effects of DASH diet on weight loss and metabolic status in adults with non‐alcoholic fatty liver disease: a randomized clinical trial
by Razavi Zade, Mohsen and Telkabadi, Mohammad Hosein and Bahmani, Fereshteh and Salehi, Behnaz and Farshbaf, Shima and Asemi, Zatollah
Liver International, ISSN 1478-3223, 04/2016, Volume 36, Issue 4, pp. 563 - 571
Background & Aims: This study was designed to determine the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on weight loss and metabolic... 
inflammation | non‐alcoholic fatty liver disease | DASH | metabolic profiles | oxidative stress | Metabolic profiles | Oxidative stress | Inflammation | Non-alcoholic fatty liver disease | POLYCYSTIC-OVARY-SYNDROME | C-REACTIVE PROTEIN | non-alcoholic fatty liver disease | BLOOD-PRESSURE | TYPE-2 DIABETIC-PATIENTS | GLUCOSE-TOLERANCE TEST | INSULIN-RESISTANCE | HYPERTENSION EATING PLAN | LIPID PROFILES | GASTROENTEROLOGY & HEPATOLOGY | HORMONE BINDING GLOBULIN | Obesity - diet therapy | Caloric Restriction | Humans | Middle Aged | Male | Insulin - blood | Obesity - blood | Diet, Reducing | Non-alcoholic Fatty Liver Disease - blood | Iran | Time Factors | Lipids - blood | Adult | Female | Obesity - diagnosis | Body Mass Index | Inflammation Mediators - blood | Insulin Resistance | Obesity - physiopathology | Treatment Outcome | Biomarkers - blood | Non-alcoholic Fatty Liver Disease - physiopathology | Energy Metabolism | Weight Loss | Non-alcoholic Fatty Liver Disease - diagnosis | Aged | Non-alcoholic Fatty Liver Disease - diet therapy | Patient Compliance | Blood Glucose - metabolism | Health Status | Hypertension | Obesity | C-reactive protein | Phosphatases | Food habits | Weight loss | Triglycerides | Proteins | Fatty liver | Nitric oxide | Physiological aspects | Insulin resistance | Adults | Index Medicus
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9. Full Text Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway
by Zhang, Yong and Chen, Ming‐liang and Zhou, Yong and Yi, Long and Gao, Yan‐xiang and Ran, Li and Chen, Shi‐hui and Zhang, Ting and Zhou, Xi and Zou, Dan and Wu, Bin and Wu, Ying and Chang, Hui and Zhu, Jun‐dong and Zhang, Qian‐yong and Mi, Man‐tian
Molecular Nutrition & Food Research, ISSN 1613-4125, 08/2015, Volume 59, Issue 8, pp. 1443 - 1457
ScopeResveratrol (RSV), a natural polyphenol, has been reported to attenuate nonalcoholic fatty liver disease (NAFLD); however, its underlying mechanism is... 
NAFLD | Treatment | Hepatocyte | SIRT1 | Resveratrol | ACTIVATION | LIPID-METABOLISM | PROTEIN-KINASE | FOOD SCIENCE & TECHNOLOGY | NONALCOHOLIC FATTY LIVER | DIET | INFLAMMATION | DISEASE | AMPK | HEALTH | Sirtuin 1 - metabolism | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Stilbenes - therapeutic use | Antioxidants - metabolism | Humans | Stilbenes - metabolism | Mice, 129 Strain | Sirtuin 1 - genetics | Autophagy - drug effects | Fatty Acids, Nonesterified - metabolism | Liver - drug effects | RNA Interference | Enzyme Induction - drug effects | Sirtuin 1 - chemistry | Cyclic AMP - metabolism | Fatty Acids, Nonesterified - adverse effects | Microscopy, Electron, Transmission | Second Messenger Systems - drug effects | Liver - ultrastructure | Liver - metabolism | Enzyme Inhibitors - pharmacology | Non-alcoholic Fatty Liver Disease - metabolism | Adenylyl Cyclases - metabolism | Sirtuin 1 - antagonists & inhibitors | Hep G2 Cells | Cyclic AMP - antagonists & inhibitors | Antioxidants - therapeutic use | Animals | Adenylyl Cyclases - chemistry | Lipid Metabolism - drug effects | Fatty Acids, Nonesterified - antagonists & inhibitors | Cyclic AMP - agonists | Non-alcoholic Fatty Liver Disease - diet therapy | Adenylyl Cyclases - genetics | Dietary Supplements | Triglycerides | Liver diseases | Fatty acids | Liver | Index Medicus
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10. Full Text Dietary salmon milt extracts attenuate hepatosteatosis and liver dysfunction in diet‐induced fatty liver model
by Sakurai, Toshihiro and Hayasaka, Takahiro and Sekiguchi, Hirotaka and Satoh, Hiroshi and Chen, Zhen and Chiba, Hitoshi and Hui, Shu‐Ping
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 03/2019, Volume 99, Issue 4, pp. 1675 - 1681
BACKGROUND Dietary nucleotides have several reported beneficial effects. Here, we report on a proteomic analysis of the effect of dietary nucleotides-rich... 
salmon milt extract | fatty liver | mitochondria | weight regain | liver function | FOOD SCIENCE & TECHNOLOGY | INVOLVEMENT | MUSCLE | INJURY | ALPHA | NUCLEOTIDES | OBESITY | METABOLISM | STEATOSIS | AGRICULTURE, MULTIDISCIPLINARY | MITOCHONDRIAL DYSFUNCTION | CHEMISTRY, APPLIED | EXPRESSION | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Carnitine O-Palmitoyltransferase - genetics | Transferases (Other Substituted Phosphate Groups) - genetics | Humans | Semen - chemistry | Diet, High-Fat - adverse effects | Male | Alanine Transaminase - blood | Transferases (Other Substituted Phosphate Groups) - metabolism | Mitochondria - genetics | Carnitine O-Palmitoyltransferase - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Membrane Proteins - metabolism | Non-alcoholic Fatty Liver Disease - genetics | Membrane Proteins - genetics | Salmon | Liver - metabolism | PPAR alpha - genetics | Mitochondria - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Nucleotides - metabolism | Animals | Aspartate Aminotransferases - blood | Mice | Non-alcoholic Fatty Liver Disease - diet therapy | PPAR alpha - metabolism | Proteins | Chemical industry | Herbicides | Pesticides industry | Membrane lipids | Fatty liver | Analysis | Liver | Body weight | Cardiolipin | Nucleotides | Carbohydrates | Alanine | Liver diseases | Thioredoxin | Palmitoyltransferase | High carbohydrate diet | Carnitine palmitoyltransferase | Carnitine | Steatosis | Organic chemistry | Mitochondria | Diet | Bioenergetics | Rodents | Index Medicus
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