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Nature medicine, ISSN 1546-170X, 2017, Volume 23, Issue 6, pp. 733 - 741
Blood vessels in the central nervous system (CNS) are controlled by neuronal activity. For example, widespread vessel constriction (vessel tone) is induced by... 
MEDICINE, RESEARCH & EXPERIMENTAL | PIAL VESSELS | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRACE AMINES | SYNAPTIC-TRANSMISSION | HYPOXIA | CELL BIOLOGY | CENTRAL-NERVOUS-SYSTEM | LOCOMOTOR FUNCTION | CEREBRAL-ARTERIES | RECEPTORS | BRAIN | Capillaries - pathology | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Receptors, Adrenergic, alpha-2 - metabolism | Transcriptome | Capillaries - drug effects | RNA, Messenger - metabolism | Oxygen - metabolism | Hypoxia - metabolism | Receptors, Serotonin, 5-HT1 - metabolism | Spinal Cord Injuries - pathology | Receptor, Serotonin, 5-HT1B - metabolism | Aromatic-L-Amino-Acid Decarboxylases - metabolism | Tyramine - metabolism | Capillaries - metabolism | Locomotion - drug effects | Injections, Spinal | Capillaries - physiopathology | Spinal Cord Injuries - metabolism | Pericytes - metabolism | Vasoconstriction | Rats | Microscopy, Interference | Oxygen Inhalation Therapy | Microscopy, Confocal | Animals | Norepinephrine - metabolism | Tryptamines - metabolism | Serotonin - metabolism | Spinal Cord Injuries - physiopathology | Biogenic Monoamines - metabolism | Locomotion - physiology | Enzymes | Care and treatment | Analysis | Tryptophan | Spinal cord injuries | Dosage and administration | Drug therapy | Health aspects | Noradrenaline | Blood flow | spinal cord injury | AADC | hypoxia | pericyte | capillary | locomotion | Trace amines | neurovascular coupling | 5-HT1B receptor | motoneurons | ischemia
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 358, Issue 6361, pp. 321 - 326
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2007, Volume 317, Issue 5843, pp. 1390 - 1393
Tricyclic antidepressants exert their pharmacological effect--inhibiting the reuptake of serotonin, norepinephrine, and dopamine--by directly blocking... 
Molecules | Salts | Neurotransmitters | Antidepressants | Reuptake | Serotonin plasma membrane transport proteins | Neurotransmitter transport proteins | Reports | Pharmacology | Inhibitory concentration 50 | Crystal structure | SENSITIVE DOPAMINE TRANSPORTER | NOREPINEPHRINE TRANSPORTERS | MULTIDISCIPLINARY SCIENCES | ION-BINDING | MONOAMINE TRANSPORTERS | SEROTONIN | INHIBITORS | Dopamine - chemistry | Antidepressive Agents, Tricyclic - metabolism | Caenorhabditis elegans Proteins - chemistry | Humans | Bacterial Proteins - chemistry | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Serotonin - chemistry | Dopamine Uptake Inhibitors - metabolism | Drosophila Proteins - metabolism | Antidepressive Agents, Tricyclic - chemistry | Neurotransmitter Uptake Inhibitors - metabolism | Desipramine - metabolism | Conserved Sequence | Binding Sites | Dopamine - metabolism | Serotonin Uptake Inhibitors - metabolism | Amino Acid Sequence | Cell Line | Leucine - metabolism | Norepinephrine Plasma Membrane Transport Proteins - antagonists & inhibitors | Models, Molecular | Serotonin Uptake Inhibitors - chemistry | Drosophila Proteins - chemistry | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Leucine - chemistry | Sequence Homology, Amino Acid | Animals | Norepinephrine - metabolism | Desipramine - chemistry | Neurotransmitter Uptake Inhibitors - chemistry | Norepinephrine - chemistry | Serotonin - metabolism | Dopamine Uptake Inhibitors - chemistry | Protein Binding | Bacterial Proteins - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - chemistry | Protein Conformation | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Norepinephrine Plasma Membrane Transport Proteins - chemistry | Leucine | Structure | Desipramine | Health aspects | Antidepressants, Tricyclic | Inhibitor drugs | Psychiatry | Binding sites
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 12/2016, Volume 311, Issue 6, pp. H1360 - H1366
... (K/X), and low-or high-dose isoflurane (ISO)] on hemodynamics, cardiac function, and glucose and lipid metabolism in Sprague-Dawley rats... 
Ketamine-xylazine | Pentobarbital sodium | Isoflurane | pentobarbital sodium | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ketamine-xylazine | MECHANISMS | BODY-TEMPERATURE | COMBINATION | BLOOD-PRESSURE | INSULIN | IMPACT | PERIPHERAL VASCULAR DISEASE | MICE | isoflurane | STRESS | HYPERTENSIVE-RATS | Renin - metabolism | Anesthetics, Dissociative - pharmacology | Isoflurane - pharmacology | Pentobarbital - pharmacology | Male | Fatty Acids, Nonesterified - metabolism | Heart Rate - drug effects | Aldosterone - metabolism | Xylazine - pharmacology | Renin - drug effects | Blood Pressure - drug effects | Dopamine - metabolism | Anesthetics, Inhalation - pharmacology | Angiotensin II - drug effects | Echocardiography | Angiotensin II - metabolism | Cholesterol, HDL - drug effects | Cholesterol, HDL - metabolism | Aorta - drug effects | Insulin Resistance | Rats | Cholesterol, LDL - drug effects | Cholesterol - metabolism | Rats, Sprague-Dawley | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | Animals | Norepinephrine - metabolism | Lipid Metabolism - drug effects | Cholesterol, LDL - metabolism | Glucose - metabolism | Renin-Angiotensin System - drug effects | Hemodynamics - drug effects | Hypnotics and Sedatives - pharmacology | Blood Glucose - metabolism | Ketamine - pharmacology | Epinephrine - metabolism
Journal Article
Cell and tissue research, ISSN 1432-0878, 2015, Volume 363, Issue 3, pp. 693 - 712
.... However, studies linking the structural effects of CgA deficiency with secretory performance and cell metabolism in the adrenomedullary chromaffin cells in vivo have not previously been reported... 
Human Genetics | Epinephrine | Mitochondria | Biomedicine | Proteomics | Synaptic vesicle | Molecular Medicine | Norepinephrine | Dense core vesicle | SECRETOGRANIN-III | TYROSINE-HYDROXYLASE ACTIVITY | SECRETORY VESICLES | NEUROTRANSMITTER RELEASE | SYNAPTIC-TRANSMISSION | TARGETED ABLATION | OSMOTIC-PRESSURE | AXONAL-TRANSPORT | INDUCED INSULIN-RESISTANCE | CELL BIOLOGY | ADRENAL-MEDULLA | Synaptic Vesicles - metabolism | Catecholamines - metabolism | Golgi Apparatus - drug effects | Humans | Endoplasmic Reticulum - metabolism | Chromaffin Granules - metabolism | Endoplasmic Reticulum - ultrastructure | Exocytosis - drug effects | Chromogranin A - deficiency | Glycogen - metabolism | Chromogranin A - metabolism | Adrenal Glands - drug effects | Chromaffin Granules - ultrastructure | Dopamine - metabolism | Splanchnic Nerves - drug effects | Insulin - pharmacology | Endocytosis - drug effects | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Blotting, Western | Mice, Knockout | Animals | Norepinephrine - metabolism | Adrenal Glands - metabolism | Glucose - metabolism | Synaptic Vesicles - drug effects | Golgi Apparatus - metabolism | Splanchnic Nerves - metabolism | Chromaffin Granules - drug effects | Energy Metabolism - drug effects | Epinephrine - metabolism | Glycogen | Catecholamines | Mitochondrial DNA | Proteins | Cellular biology | Metabolism | Morphology
Journal Article
PLoS biology, ISSN 1545-7885, 2019, Volume 17, Issue 1, p. e2006571
Beiging of white adipose tissue (WAT) is a particularly appealing target for therapeutics in the treatment of metabolic diseases through norepinephrine... 
NOREPINEPHRINE UPTAKE | THERMOGENESIS | LIPOLYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | GENES | BIOLOGY | CAUSAL VARIANTS | DIFFERENTIATION | EXPRESSION | FAT-CELL | BROWN | Norepinephrine - pharmacology | Catecholamines - metabolism | Humans | Octamer Transcription Factor-3 - biosynthesis | Adipose Tissue, White - metabolism | Male | Octamer Transcription Factor-3 - genetics | Thermogenesis - physiology | Adipose Tissue - metabolism | HEK293 Cells | Cyclic AMP-Dependent Protein Kinases - metabolism | Organic Cation Transport Proteins - metabolism | Signal Transduction | Mice, Inbred C57BL | Organic Cation Transport Proteins - biosynthesis | Obesity - metabolism | Macrophages - metabolism | Animals | Energy Metabolism | Adipocytes - metabolism | Octamer Transcription Factor-3 - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Organic Cation Transport Proteins - genetics | Adipose Tissue, Beige - metabolism | Adipose tissues | Physiological aspects | Catecholamines | Fat cells | Carrier proteins | Protein kinase A | Bioengineering | Adipose tissue | Body fat | Disease | Hormones | Adipocytes | Proteins | Mitochondria | Life sciences | Obesity | Route selection | Organic cation transporter | AMP | Body temperature | Medical treatment | Metabolism | Cyclic AMP response element-binding protein | Gene expression | Catecholamine | Ablation | Lipolysis | Browning | Thermogenesis | Pharmacy | Software | Transporter | Metabolic disorders | Metabolic rate | Laboratories | Oct-4 protein | Genes | Biology | Kinases | Macrophages | Glucose metabolism | Transcription activation | Schools | Pharmaceutical sciences | Supervision | Adenosine monophosphate | Neurons | Therapeutic applications | Inflammation | Medicine | Adenosine kinase | Glycolysis | Sympathetic nerves | Norepinephrine | Adrenergic receptors | Cations
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 06/2013, Volume 85, Issue 12, pp. 1803 - 1815
Journal Article
Nutrition, metabolism, and cardiovascular diseases, ISSN 0939-4753, 2013, Volume 23, Issue 6, pp. 582 - 590
Abstract Background and aim Brown adipose tissue (BAT) plays a major role in body energy expenditure counteracting obesity and obesity-associated morbidities.... 
Cardiovascular | Exercise | BAT | Mitochondrial function | WAT | Gene expression | MCT-1 | White-to-brown transdifferentiation | CARDIAC & CARDIOVASCULAR SYSTEMS | ADIPOCYTES | TRANSPORTER | ANGIOGENESIS | MESSENGER-RNA EXPRESSION | MOUSE | RATS | OBESITY | NUTRITION & DIETETICS | LACTATE | ENDOCRINOLOGY & METABOLISM | FAT | RESISTANCE | Ion Channels - genetics | Adipocytes - cytology | Male | Mitochondrial Proteins - genetics | Sympathetic Nervous System - metabolism | Running - physiology | Monocarboxylic Acid Transporters - metabolism | Forkhead Transcription Factors - metabolism | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Cell Transdifferentiation | Energy Metabolism - physiology | Lactic Acid - metabolism | Rats | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Intra-Abdominal Fat - metabolism | Physical Conditioning, Animal - physiology | Rats, Sprague-Dawley | Symporters - metabolism | Obesity - metabolism | Transcription Factors - metabolism | Animals | Norepinephrine - metabolism | Thermogenesis | Ion Channels - metabolism | Adipocytes - metabolism | Symporters - genetics | Adipose Tissue, Brown - metabolism | Monocarboxylic Acid Transporters - genetics | Uncoupling Protein 1 | Adipose tissues | Physiological aspects
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 8, p. e103929
Dynamic thalamic regulation of sensory signals allows the cortex to adjust better to rapidly changing behavioral, physiological and environmental demands. To... 
VENTROBASAL THALAMUS | DOPAMINE INNERVATION | MULTIDISCIPLINARY SCIENCES | NORADRENERGIC MODULATION | LOCUS-COERULEUS STIMULATION | OREXIN NEURONS | VENTROPOSTEROMEDIAL NUCLEUS | MELANIN-CONCENTRATING HORMONE | CEREBRAL-CORTEX | LATERAL GENICULATE-NUCLEUS | SYNAPTIC ORGANIZATION | Neurons - pathology | Glutamates - metabolism | Male | Vasopressins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Melanins - metabolism | Oxytocin - metabolism | Histamine - metabolism | Migraine Disorders - physiopathology | Pituitary Hormones - metabolism | Trigeminal Nerve - physiopathology | Calcitonin Gene-Related Peptide - metabolism | Dopamine - metabolism | Biomarkers - metabolism | Eating | Orexins | Anxiety - psychology | Neurotransmitter Agents - metabolism | Anxiety - physiopathology | Neuropeptides - metabolism | Hypothalamus - physiopathology | Rats, Sprague-Dawley | Trigeminal Nerve - blood supply | Animals | Norepinephrine - metabolism | Sleep | Thalamus - physiopathology | Hypothalamic Hormones - metabolism | Migraine Disorders - psychology | Serotonin - metabolism | Brain Stem - physiopathology | Stress, Psychological - physiopathology | Immunohistochemistry | Dextran | Histamine | Pituitary hormones | Neurons | Migraine | Physiological aspects | GABA | Glutamate | Stress (Psychology) | Neurophysiology | Headache | Neurosciences | Cognitive ability | Homeostasis | Critical care | Neuropeptides | Environmental changes | Cortex (somatosensory) | Density | Medical schools | γ-Aminobutyric acid | Pain | Pathways | Autonomic nervous system | Rodents | Thalamus | Physiology | Anxiety | Bioindicators | Noradrenaline | Medical research | Emotional behavior | Pain perception | Dopamine | Serotonin | Vasopressin | Substrates | Medicine | Calcitonin gene-related peptide | Axons | Neurotransmitters | Food intake | Melanin-concentrating hormone | Biomarkers | Norepinephrine | Laboratory animals | Melanin
Journal Article