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Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, pp. 7735 - 7735
Journal Article
Nature, ISSN 0028-0836, 10/2017, Volume 550, Issue 7674, pp. 119 - 123
Catecholamine-induced lipolysis, the first step in the generation of energy substrates by the hydrolysis of triglycerides(1), declines with age(2,3). The... 
MONOAMINE-OXIDASE | CELLS | OBESITY | ACTIVATION | MULTIDISCIPLINARY SCIENCES | ACCUMULATION | IDENTIFICATION | GENE ONTOLOGY | DEFICIENCY | ADIPOSE-TISSUE | AGE | Inflammasomes - metabolism | Lipolysis - drug effects | Catecholamines - metabolism | Growth Differentiation Factor 3 - metabolism | Sterol Esterase - metabolism | Aging - drug effects | Adipose Tissue - cytology | Caspase 1 - metabolism | Gene Expression Profiling | Growth Differentiation Factor 3 - deficiency | Lipolysis - genetics | Adipose Tissue - metabolism | Aging - genetics | Monoamine Oxidase Inhibitors - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Lipase - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein - deficiency | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | Norepinephrine - metabolism | Growth Differentiation Factor 3 - genetics | Adipocytes - metabolism | Mice | Adipose Tissue - drug effects | Catecholamines - pharmacology | Aging - metabolism | Monoamine Oxidase - metabolism | Aging | Observations | Catecholamine metabolism | Health aspects | Elderly people | Adipose tissue | Oxidase | Genomes | Adipocytes | Kinases | Macrophages | Lipase | Caspase-1 | Reduction | Energy resources | Clonal deletion | Deletion | Noradrenaline | Age | Enzymes | Starvation | Fasting | Body temperature | Aging (artificial) | Glycerol | Caspase | Principal components analysis | Triglycerides | Inflammation | Bioavailability | Metabolism | Gene expression | Sympathetic nervous system | Catecholamine | Fatty acids | Substrates | Lipolysis | Amine oxidase (flavin-containing) | Signaling | Catabolism | Norepinephrine | Elderly | Geriatrics | Index Medicus
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2017, Volume 23, Issue 6, pp. 733 - 741
Blood vessels in the central nervous system (CNS) are controlled by neuronal activity. For example, widespread vessel constriction (vessel tone) is induced by... 
MEDICINE, RESEARCH & EXPERIMENTAL | PIAL VESSELS | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRACE AMINES | SYNAPTIC-TRANSMISSION | HYPOXIA | CELL BIOLOGY | CENTRAL-NERVOUS-SYSTEM | LOCOMOTOR FUNCTION | CEREBRAL-ARTERIES | RECEPTORS | BRAIN | Capillaries - pathology | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Receptors, Adrenergic, alpha-2 - metabolism | Transcriptome | Capillaries - drug effects | RNA, Messenger - metabolism | Oxygen - metabolism | Hypoxia - metabolism | Receptors, Serotonin, 5-HT1 - metabolism | Spinal Cord Injuries - pathology | Receptor, Serotonin, 5-HT1B - metabolism | Aromatic-L-Amino-Acid Decarboxylases - metabolism | Tyramine - metabolism | Capillaries - metabolism | Locomotion - drug effects | Injections, Spinal | Capillaries - physiopathology | Spinal Cord Injuries - metabolism | Pericytes - metabolism | Vasoconstriction | Rats | Microscopy, Interference | Oxygen Inhalation Therapy | Microscopy, Confocal | Animals | Norepinephrine - metabolism | Tryptamines - metabolism | Serotonin - metabolism | Spinal Cord Injuries - physiopathology | Biogenic Monoamines - metabolism | Locomotion - physiology | Enzymes | Care and treatment | Analysis | Tryptophan | Spinal cord injuries | Dosage and administration | Drug therapy | Health aspects | Noradrenaline | Blood flow | Index Medicus | spinal cord injury | AADC | hypoxia | pericyte | capillary | locomotion | Trace amines | neurovascular coupling | 5-HT1B receptor | motoneurons | ischemia
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2016, Volume 311, Issue 6, pp. H1360 - H1366
Anesthesia can affect respiratory, circulatory, and endocrine systems but is necessary for certain experimental procedures such as echocardiography and blood... 
Ketamine-xylazine | Pentobarbital sodium | Isoflurane | pentobarbital sodium | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ketamine-xylazine | MECHANISMS | BODY-TEMPERATURE | COMBINATION | BLOOD-PRESSURE | INSULIN | IMPACT | PERIPHERAL VASCULAR DISEASE | MICE | isoflurane | STRESS | HYPERTENSIVE-RATS | Renin - metabolism | Anesthetics, Dissociative - pharmacology | Isoflurane - pharmacology | Pentobarbital - pharmacology | Male | Fatty Acids, Nonesterified - metabolism | Heart Rate - drug effects | Aldosterone - metabolism | Xylazine - pharmacology | Renin - drug effects | Blood Pressure - drug effects | Dopamine - metabolism | Anesthetics, Inhalation - pharmacology | Angiotensin II - drug effects | Echocardiography | Angiotensin II - metabolism | Cholesterol, HDL - drug effects | Cholesterol, HDL - metabolism | Aorta - drug effects | Insulin Resistance | Rats | Cholesterol, LDL - drug effects | Cholesterol - metabolism | Rats, Sprague-Dawley | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | Animals | Norepinephrine - metabolism | Lipid Metabolism - drug effects | Cholesterol, LDL - metabolism | Glucose - metabolism | Renin-Angiotensin System - drug effects | Hemodynamics - drug effects | Hypnotics and Sedatives - pharmacology | Blood Glucose - metabolism | Ketamine - pharmacology | Epinephrine - metabolism | Lipids | Anesthesia | Ultrasonic imaging | Glucose | Metabolism | Rodents | Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 05/2017, Volume 66, Issue 5, pp. 1146 - 1158
Although many biological functions of activating transcription factor 4 (ATF4) have been identified, a role of hypothalamic ATF4 in the regulation of energy... 
AMINO-ACID | LIPID-METABOLISM | LEPTIN ACTION | ENDOCRINOLOGY & METABOLISM | CONNECTS ER STRESS | MICE | AGRP NEURONS | AUTOPHAGY | DIET-INDUCED OBESITY | LIVER STEATOSIS | BALANCE | Leptin - metabolism | Adipose Tissue, White - metabolism | Autophagy-Related Protein 5 - genetics | Adipose Tissue - metabolism | Neurons - metabolism | Energy Metabolism - genetics | Real-Time Polymerase Chain Reaction | Adipose Tissue, White - pathology | Glucose Tolerance Test | Signal Transduction | Growth Hormone - metabolism | Adipose Tissue - pathology | Insulin Resistance | Activating Transcription Factor 4 - genetics | Organ Size | Adipose Tissue, Brown - pathology | Blotting, Western | Mice, Knockout | Pro-Opiomelanocortin - metabolism | Insulin - metabolism | Animals | Hypothalamus - metabolism | Norepinephrine - metabolism | Activating Transcription Factor 4 - metabolism | Hypothalamus - cytology | Fluorescent Antibody Technique | Autophagy-Related Protein 5 - metabolism | Adipose Tissue, Brown - metabolism | Corticosterone - metabolism | Mice | Blood Glucose - metabolism | Homeostasis | Obesity | Transcription factors | Care and treatment | Research | Melanocyte-stimulating hormone | Body fat | Neurons | Activating transcription factor 4 | Energy expenditure | Proopiomelanocortin | Hypothalamus | High fat diet | Glucose tolerance | Signal transduction | Energy balance | Intolerance | Energy | Clonal deletion | Leptin | Oils & fats | Phagocytosis | Metabolic disorders | Index Medicus | Abridged Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2007, Volume 317, Issue 5843, pp. 1390 - 1393
Tricyclic antidepressants exert their pharmacological effect--inhibiting the reuptake of serotonin, norepinephrine, and dopamine--by directly blocking... 
Molecules | Salts | Neurotransmitters | Antidepressants | Reuptake | Serotonin plasma membrane transport proteins | Neurotransmitter transport proteins | Reports | Pharmacology | Inhibitory concentration 50 | Crystal structure | SENSITIVE DOPAMINE TRANSPORTER | NOREPINEPHRINE TRANSPORTERS | MULTIDISCIPLINARY SCIENCES | ION-BINDING | MONOAMINE TRANSPORTERS | SEROTONIN | INHIBITORS | Dopamine - chemistry | Antidepressive Agents, Tricyclic - metabolism | Caenorhabditis elegans Proteins - chemistry | Humans | Bacterial Proteins - chemistry | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Serotonin - chemistry | Dopamine Uptake Inhibitors - metabolism | Drosophila Proteins - metabolism | Antidepressive Agents, Tricyclic - chemistry | Neurotransmitter Uptake Inhibitors - metabolism | Desipramine - metabolism | Conserved Sequence | Binding Sites | Dopamine - metabolism | Serotonin Uptake Inhibitors - metabolism | Amino Acid Sequence | Cell Line | Leucine - metabolism | Norepinephrine Plasma Membrane Transport Proteins - antagonists & inhibitors | Models, Molecular | Serotonin Uptake Inhibitors - chemistry | Drosophila Proteins - chemistry | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Leucine - chemistry | Sequence Homology, Amino Acid | Animals | Norepinephrine - metabolism | Desipramine - chemistry | Neurotransmitter Uptake Inhibitors - chemistry | Norepinephrine - chemistry | Serotonin - metabolism | Dopamine Uptake Inhibitors - chemistry | Protein Binding | Bacterial Proteins - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - chemistry | Protein Conformation | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Norepinephrine Plasma Membrane Transport Proteins - chemistry | Leucine | Structure | Desipramine | Health aspects | Antidepressants, Tricyclic | Inhibitor drugs | Psychiatry | Binding sites | Index Medicus
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 3/2016, Volume 363, Issue 3, pp. 693 - 712
Chromogranin A (CgA) is a prohormone and granulogenic factor in neuroendocrine tissues with a regulated secretory pathway. The impact of CgA depletion on... 
Human Genetics | Epinephrine | Mitochondria | Biomedicine | Proteomics | Synaptic vesicle | Molecular Medicine | Norepinephrine | Dense core vesicle | SECRETOGRANIN-III | TYROSINE-HYDROXYLASE ACTIVITY | SECRETORY VESICLES | NEUROTRANSMITTER RELEASE | SYNAPTIC-TRANSMISSION | TARGETED ABLATION | OSMOTIC-PRESSURE | AXONAL-TRANSPORT | INDUCED INSULIN-RESISTANCE | CELL BIOLOGY | ADRENAL-MEDULLA | Synaptic Vesicles - metabolism | Catecholamines - metabolism | Golgi Apparatus - drug effects | Humans | Endoplasmic Reticulum - metabolism | Chromaffin Granules - metabolism | Endoplasmic Reticulum - ultrastructure | Exocytosis - drug effects | Chromogranin A - deficiency | Glycogen - metabolism | Chromogranin A - metabolism | Adrenal Glands - drug effects | Chromaffin Granules - ultrastructure | Dopamine - metabolism | Splanchnic Nerves - drug effects | Insulin - pharmacology | Endocytosis - drug effects | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Blotting, Western | Mice, Knockout | Animals | Norepinephrine - metabolism | Adrenal Glands - metabolism | Glucose - metabolism | Synaptic Vesicles - drug effects | Golgi Apparatus - metabolism | Splanchnic Nerves - metabolism | Chromaffin Granules - drug effects | Energy Metabolism - drug effects | Epinephrine - metabolism | Glycogen | Catecholamines | Mitochondrial DNA | Proteins | Cellular biology | Metabolism | Morphology | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 06/2013, Volume 85, Issue 12, pp. 1803 - 1815
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1537 - 1541
The serotonin transporter (SERT) ensures the recapture of serotonin and is the pharmacological target of selective serotonin reuptake inhibitor (SSRI)... 
Receptors | MicroRNA | Serotonin agents | Neurons | Antidepressants | Serotonin receptors | REPORTS | Cell lines | Serotonin plasma membrane transport proteins | Adrenergic neurons | Locus coeruleus | LOCUS-COERULEUS | CELLS | RECEPTOR | RECOGNITION | RAT | MULTIDISCIPLINARY SCIENCES | Up-Regulation | Protein Biosynthesis | Humans | MicroRNAs - metabolism | Nerve Growth Factors - metabolism | Antidepressive Agents, Second-Generation - administration & dosage | Raphe Nuclei - metabolism | Serotonin Plasma Membrane Transport Proteins - genetics | Neurons - metabolism | 3' Untranslated Regions | Neurons - drug effects | Serotonin Uptake Inhibitors - metabolism | Cell Line | Fluoxetine - pharmacology | S100 Calcium Binding Protein beta Subunit | MicroRNAs - administration & dosage | Depression | S100 Proteins - metabolism | Antidepressive Agents, Second-Generation - pharmacology | Serotonin Plasma Membrane Transport Proteins - metabolism | Animals | Norepinephrine - metabolism | Raphe Nuclei - drug effects | Serotonin Uptake Inhibitors - administration & dosage | Serotonin - metabolism | Fluoxetine - administration & dosage | Fluoxetine - metabolism | Mice | MicroRNAs - genetics | HeLa Cells | Antidepressive Agents, Second-Generation - metabolism | Serotonin Uptake Inhibitors - pharmacology | Locus Coeruleus - metabolism | Pharmacogenetics | Serotonin | Physiological aspects | Serotonin uptake inhibitors | Dosage and administration | Research | Health aspects | Pharmacology | Index Medicus
Journal Article
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 2012, Volume 23, Issue 6, pp. 582 - 590
Abstract Background and aim Brown adipose tissue (BAT) plays a major role in body energy expenditure counteracting obesity and obesity-associated morbidities.... 
Cardiovascular | Exercise | BAT | Mitochondrial function | WAT | Gene expression | MCT-1 | White-to-brown transdifferentiation | CARDIAC & CARDIOVASCULAR SYSTEMS | ADIPOCYTES | TRANSPORTER | ANGIOGENESIS | MESSENGER-RNA EXPRESSION | MOUSE | RATS | OBESITY | NUTRITION & DIETETICS | LACTATE | ENDOCRINOLOGY & METABOLISM | FAT | RESISTANCE | Ion Channels - genetics | Adipocytes - cytology | Male | Mitochondrial Proteins - genetics | Sympathetic Nervous System - metabolism | Running - physiology | Monocarboxylic Acid Transporters - metabolism | Forkhead Transcription Factors - metabolism | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Cell Transdifferentiation | Energy Metabolism - physiology | Lactic Acid - metabolism | Rats | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Intra-Abdominal Fat - metabolism | Physical Conditioning, Animal - physiology | Rats, Sprague-Dawley | Symporters - metabolism | Obesity - metabolism | Transcription Factors - metabolism | Animals | Norepinephrine - metabolism | Thermogenesis | Ion Channels - metabolism | Adipocytes - metabolism | Symporters - genetics | Adipose Tissue, Brown - metabolism | Monocarboxylic Acid Transporters - genetics | Uncoupling Protein 1 | Adipose tissues | Physiological aspects | Index Medicus
Journal Article