X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (9667) 9667
Publication (1163) 1163
Book Review (1047) 1047
Conference Proceeding (125) 125
Book Chapter (122) 122
Dissertation (52) 52
Book / eBook (1) 1
Data Set (1) 1
Magazine Article (1) 1
Paper (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
nrf2 (7181) 7181
index medicus (6887) 6887
oxidative stress (5763) 5763
animals (4230) 4230
humans (3438) 3438
nf-e2-related factor 2 - metabolism (3255) 3255
mice (2593) 2593
biochemistry & molecular biology (2521) 2521
antioxidants (2375) 2375
activation (1969) 1969
nf-e2-related factor 2 - genetics (1751) 1751
male (1714) 1714
apoptosis (1580) 1580
transcription factor nrf2 (1578) 1578
expression (1522) 1522
pharmacology & pharmacy (1497) 1497
inflammation (1403) 1403
cell biology (1359) 1359
oxidative stress - drug effects (1254) 1254
rats (1228) 1228
gene expression (1171) 1171
proteins (1102) 1102
signal transduction (1097) 1097
cancer (1087) 1087
gene-expression (1078) 1078
reactive oxygen species - metabolism (1067) 1067
analysis (1061) 1061
heme oxygenase-1 (1039) 1039
enzymes (975) 975
pathway (973) 973
cells (969) 969
signal transduction - drug effects (955) 955
toxicology (937) 937
nf-kappa-b (907) 907
keap1 (896) 896
article (845) 845
glutathione (839) 839
female (808) 808
induction (806) 806
antioxidant (777) 777
cell line (762) 762
reactive oxygen species (760) 760
rodents (760) 760
heme (744) 744
neurosciences (736) 736
endocrinology & metabolism (731) 731
respiratory system (720) 720
cells, cultured (713) 713
heme oxygenase-1 - metabolism (709) 709
cell line, tumor (702) 702
antioxidant response element (698) 698
antioxidants - metabolism (697) 697
antioxidants - pharmacology (683) 683
mice, inbred c57bl (683) 683
oncology (654) 654
genes (627) 627
mechanisms (605) 605
liver (603) 603
research (599) 599
transcription factors (597) 597
kelch-like ech-associated protein 1 (583) 583
medicine, research & experimental (568) 568
apoptosis - drug effects (552) 552
inhibition (543) 543
up-regulation (541) 541
physiological aspects (540) 540
health aspects (530) 530
mice, knockout (524) 524
autophagy (519) 519
stress (516) 516
cell survival - drug effects (509) 509
in-vitro (508) 508
disease models, animal (507) 507
signaling pathway (494) 494
phosphorylation (483) 483
glutathione - metabolism (482) 482
environment and public health (476) 476
rats, sprague-dawley (469) 469
toxicity (454) 454
transcription factor (443) 443
nadh dehydrogenase (437) 437
dose-response relationship, drug (435) 435
biology (433) 433
food science & technology (432) 432
heme oxygenase-1 - genetics (428) 428
disease (427) 427
metabolism (427) 427
medicine (417) 417
chemistry, medicinal (415) 415
gene expression regulation - drug effects (411) 411
superoxide (403) 403
oxidation-reduction (398) 398
in-vivo (396) 396
gene expression regulation (394) 394
rna (393) 393
kinases (391) 391
brain (385) 385
neuroprotection (385) 385
ho-1 (384) 384
genetic aspects (383) 383
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (9721) 9721
Korean (51) 51
Chinese (46) 46
Japanese (25) 25
German (9) 9
Spanish (7) 7
French (4) 4
Russian (4) 4
Czech (2) 2
Polish (2) 2
Catalan (1) 1
Croatian (1) 1
Portuguese (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2017, Volume 114, Issue 23, pp. E4676 - E4685
The activity of the transcription factor nuclear factor-erythroid 2 p45-derived factor 2 (NRF2) is orchestrated and amplified through enhanced transcription of... 
Antiinflammatory responses | KEAP1/NRF2/ARE signaling | Huntington's disease | Human neural stem cells | NRF2 inducer | human neural stem cells | OXIDATIVE STRESS | MICROGLIAL ACTIVATION | PROTEIN | PROTEASOMAL DEGRADATION | MULTIDISCIPLINARY SCIENCES | KEAP1 | antiinflammatory responses | NEURODEGENERATIVE DISEASES | TRANSCRIPTION FACTOR NRF2 | GENE | CUL3-BASED E3 LIGASE | MOUSE MODEL | Microglia - metabolism | Humans | Middle Aged | Protein Conformation - drug effects | Male | Kelch-Like ECH-Associated Protein 1 - chemistry | Brain - metabolism | Neuroprotective Agents - pharmacology | HEK293 Cells | Adult | Female | Disease Models, Animal | Cytokines - metabolism | Microglia - drug effects | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Rats | Kelch-Like ECH-Associated Protein 1 - metabolism | Huntington Disease - metabolism | MPTP Poisoning - prevention & control | Brain - drug effects | Macrophages - metabolism | Animals | MPTP Poisoning - metabolism | NF-E2-Related Factor 2 - metabolism | Huntington Disease - genetics | Macrophages - drug effects | Aged | Mice | NF-E2-Related Factor 2 - chemistry | Neural Stem Cells - metabolism | Huntingtons disease | Transcription factors | Cytokines | Astrocytes | Stem cell transplantation | Activation | Inflammation | Patients | Microglia | Proteins | Interleukin 6 | Antioxidants | Monocytes | Allografts | Stem cells | Interleukin 1 | Neural stem cells | Mutation | Human behavior | Interleukin 8 | Ubiquitin-protein ligase | Index Medicus | Biological Sciences | PNAS Plus | NRF2 | ARE signaling | Huntington’s disease
Journal Article
Biochimica et Biophysica Acta - General Subjects, ISSN 0304-4165, 12/2016, Volume 1860, Issue 12, pp. 2793 - 2801
Background Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is an enzyme that can degrade asymmetric dimethylarginine (ADMA), an endogenous nitric oxide... 
DDAH1 | Nrf2 | ROS | iNOS
Journal Article
Genes & Development, ISSN 0890-9369, 03/2014, Volume 28, Issue 6, pp. 548 - 560
textabstractThe disruption of the NRF2 (nuclear factor erythroid-derived 2-like 2)/glutathione-mediated antioxidant defense pathway is a critical step in the... 
Circadian clock | Bleomycin | Pulmonary fibrosis | NRF2 | Glutathione
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2013, Volume 23, Issue 10, pp. 3039 - 3043
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S16 - S16
Journal Article
Biomolecules & Therapeutics(구 응용약물학회지), ISSN 1976-9148, 2018, Volume 26, Issue 1, p. 57
Nuclear factor E2-related factor 2 (NRF2) plays an important role in redox metabolism and antioxidant defense. Under normal con-ditions, NRF2 proteins are... 
NRF2 inhibitors | NRF2 | KEAP1 | Cancer
Journal Article
Journal of neuroinflammation, ISSN 1742-2094, 02/2019, Volume 16, Issue 1, pp. 24 - 24
BackgroundPrevious studies had showed that Apelin 13 could protect against apoptosis induced by ischemic/reperfusion (I/R). However, the mechanisms whereby... 
Oxidative stress | Apelin 13 | AMPK/GSK-3β/Nrf2 | Inflammation | Ischemic stroke | PROTEIN-KINASE | REPERFUSION INJURY | TRANSIENT MODEL | IMMUNOLOGY | NEUROSCIENCES | GSK-3 beta/Nrf2 | APJ RECEPTOR | TRANSCRIPTION FACTOR NRF2 | AMPK | LIGAND | CEREBRAL-ISCHEMIA | BRAIN | ISCHEMIA/REPERFUSION | Index Medicus
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 267 - 267
Conference Proceeding
BBA - General Subjects, ISSN 0304-4165, 12/2014, Volume 1840, Issue 12, pp. 3413 - 3422
Jasmonates are plant lipid-derived oxylipins that act as key signaling compounds when plants are under oxidative stress, but little is known about their... 
Plant oxylipins | Oxidative stress | SH-SY5Y | OPDA | Jasmonates | Nrf2 | CARNOSIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE SYNTHESIS | NEURODEGENERATIVE DISEASES | TRANSCRIPTION FACTOR NRF2 | BIOPHYSICS | ANTIOXIDANT | THERAPEUTIC TARGET | NRF2/ARE SIGNALING PATHWAY | KEAP1/NRF2 PATHWAY | HEME OXYGENASE-1 | PARKINSONS-DISEASE | Cells | Neuroblastoma | Index Medicus
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 2/2012, Volume 132, Issue 1, pp. 175 - 187
Journal Article
by Sun, HP and Zhu, J and Lin, HZ and Gu, K and Feng, F
EXPERT OPINION ON THERAPEUTIC PATENTS, ISSN 1354-3776, 2017, Volume 27, Issue 7, pp. 763 - 785
Introduction: The NF-E2-related factor-2 (Nrf2) is a critical transcription factor that regulates the expression of many phase II and antioxidant genes to... 
Nrf2 modulators | CANCER-CELLS | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | ACTIVATORS | DIMETHYL FUMARATE | FACTOR-2 NRF2 | TRANSCRIPTION FACTOR NRF2 | BARDOXOLONE METHYL | ANTIOXIDANT RESPONSE | PHARMACOLOGY & PHARMACY | protein-protein interaction | Nrf2 inhibitors | covalent activators | small molecules | DARK SIDE
Journal Article
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 01/2019, Volume 64, Issue 1, pp. 1 - 12
Journal Article
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 12/2016, Volume 25, Issue 17, pp. 953 - 964
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2018, Volume 129, pp. 454 - 462
Glutathione peroxidase 4 (GPX4) is a regulator of ferroptosis (iron-dependent, non-apoptotic cell death); its inhibition can render therapy-resistant cancer... 
Head and neck cancer | Ferroptosis | GPX4 | Nrf2 | p62 | ACTIVATE NRF2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | P62/SQSTM1 | FOLLOW-UP | AUTOPHAGY | CELL-DEATH | PROTECTS | TRANSCRIPTION FACTOR NRF2 | PATHWAY | ENDOCRINOLOGY & METABOLISM | DEGRADATION | Antioxidants | Development and progression | Cell death | Analysis
Journal Article