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1. Full Text NDC1: A Crucial Membrane-Integral Nucleoporin of Metazoan Nuclear Pore Complexes
by Fabrizia Stavru and Bastian B. Hülsmann and Anne Spang and Enno Hartmann and Volker C. Cordes and Dirk Görlich
The Journal of cell biology, ISSN 0021-9525, 5/2006, Volume 173, Issue 4, pp. 509 - 519
Yeasts | Nuclear pore | Phenotypes | Nuclear pore complex proteins | Cell cycle | HeLa cells | Nuclear membrane | Antibodies | Topology | Eukaryotic cells | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Conserved Sequence - genetics | Nuclear Pore Complex Proteins - metabolism | Humans | Nuclear Pore Complex Proteins - chemistry | Caenorhabditis elegans Proteins - metabolism | Gene Expression Regulation, Developmental - genetics | Molecular Sequence Data | Nuclear Pore - genetics | Protein Structure, Tertiary - genetics | Amino Acid Sequence - genetics | Nuclear Pore - metabolism | Nuclear Pore Complex Proteins - genetics | Sequence Homology, Amino Acid | Caenorhabditis elegans | Animals | Nuclear Pore - ultrastructure | Genes, Lethal - genetics | Larva - growth & development | Larva - genetics | Mice | HeLa Cells | Caenorhabditis elegans Proteins - genetics | Evolution, Molecular | Mammals | Cell membranes | Research | Proteins | Membranes | Cellular biology | Invertebrates | Index Medicus | Nuclear Pore/genetics | Amino Acid Sequence/genetics | Cellular Biology | Life Sciences | Larva/genetics | Gene Expression Regulation, Developmental/genetics | Nuclear Pore/ultrastructure | Caenorhabditis elegans Proteins/genetics | Nuclear Pore Complex Proteins/genetics | Larva/growth & development | Nuclear Pore Complex Proteins/metabolism | Nuclear Pore Complex Proteins/chemistry | Genes, Lethal/genetics | Nuclear Pore/metabolism | Conserved Sequence/genetics | Protein Structure, Tertiary/genetics | Caenorhabditis elegans Proteins/metabolism
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2. Full Text Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase
by Shigeki Nagai and Karine Dubrana and Monika Tsai-Pflugfelder and Marta B. Davidson and Tania M. Roberts and Grant W. Brown and Elisa Varela and Florence Hediger and Susan M. Gasser and Nevan J. Krogan
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2008, Volume 322, Issue 5901, pp. 597 - 602
Yeasts | Medical research | Nuclear pore | DNA damage | Ubiquitins | DNA | Imaging | Genetic loci | Reports | DNA repair | Genetic mutation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Molecular genetics | Mutagenesis. Repair | Immunoprecipitation | DNA, Fungal - genetics | Saccharomyces cerevisiae - genetics | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - metabolism | Nuclear Pore Complex Proteins - genetics | Saccharomyces cerevisiae - metabolism | Chromatin Immunoprecipitation | Recombination, Genetic | Genes, Fungal | Protein-Serine-Threonine Kinases - metabolism | Zinc Fingers | Nuclear Pore Complex Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Nuclear Pore - metabolism | Gene Conversion | Deoxyribonucleases, Type II Site-Specific - metabolism | DNA Repair | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Kinetics | Physiological aspects | Cellular proteins | Genetic aspects | Research | Ligases | Biomedical research | Yeast | Gene expression | Genomics | Index Medicus
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3. Full Text TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
by Chou, Ching-Chieh and Zhang, Yi and Umoh, Mfon E and Vaughan, Spencer W and Lorenzini, Ileana and Liu, Feilin and Sayegh, Melissa and Donlin-Asp, Paul G and Chen, Yu Han and Duong, Duc M and Seyfried, Nicholas T and Powers, Maureen A and Kukar, Thomas and Hales, Chadwick M and Gearing, Marla and Cairns, Nigel J and Boylan, Kevin B and Dickson, Dennis W and Rademakers, Rosa and Zhang, Yong-Jie and Petrucelli, Leonard and Sattler, Rita and Zarnescu, Daniela C and Glass, Jonathan D and Rossoll, Wilfried
Nature neuroscience, ISSN 1097-6256, 02/2018, Volume 21, Issue 2, pp. 228 - 239
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | C9orf72 Protein - genetics | Active Transport, Cell Nucleus - physiology | Humans | Nuclear Envelope - ultrastructure | Male | Drosophila Proteins - metabolism | Cerebral Cortex - cytology | DNA-Binding Proteins - metabolism | Frontotemporal Dementia - metabolism | Protein Aggregation, Pathological - pathology | Female | C9orf72 Protein - metabolism | Active Transport, Cell Nucleus - genetics | Neuroblastoma - pathology | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Animals, Genetically Modified | Amyotrophic Lateral Sclerosis - genetics | Drosophila | Mice, Inbred C57BL | Cells, Cultured | Nuclear Pore - genetics | DNA-Binding Proteins - genetics | Nuclear Pore - metabolism | DNA-Binding Proteins - ultrastructure | Amyotrophic Lateral Sclerosis - pathology | Animals | Larva | Amyotrophic Lateral Sclerosis - metabolism | C9orf72 Protein - ultrastructure | Embryo, Nonmammalian | Mice | Drosophila Proteins - genetics | Nuclear Envelope - pathology | Protein Aggregation, Pathological - metabolism | Fibroblasts | Amyotrophic lateral sclerosis | Research | Protein binding | Brain | Neurons | Biotin | Ribonucleic acid--RNA | Pathology | DNA-binding protein | Nucleoporins | RNA transport | Aggregates | Stem cells | Dementia disorders | Mutation | Transport | Protein transport | Frontotemporal dementia | Pluripotency | Deoxyribonucleic acid--DNA | Index Medicus
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4. Full Text Mutant Huntingtin Disrupts the Nuclear Pore Complex
by Grima, Jonathan C and Daigle, J. Gavin and Arbez, Nicolas and Cunningham, Kathleen C and Zhang, Ke and Ochaba, Joseph and Geater, Charlene and Morozko, Eva and Stocksdale, Jennifer and Glatzer, Jenna C and Pham, Jacqueline T and Ahmed, Ishrat and Peng, Qi and Wadhwa, Harsh and Pletnikova, Olga and Troncoso, Juan C and Duan, Wenzhen and Snyder, Solomon H and Ranum, Laura P.W and Thompson, Leslie M and Lloyd, Thomas E and Ross, Christopher A and Rothstein, Jeffrey D
Neuron (Cambridge, Mass.), ISSN 0896-6273, 04/2017, Volume 94, Issue 1, pp. 93 - 107.e6
RAN translation | induced pluripotent stem cell | neurodegeneration | nuclear pore complex | Thiamet-G | nucleocytoplasmic transport | Huntington’s disease | KPT-350 | C9ORF72 | O-GlcNAc | Huntington's disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Nuclear Pore Complex Proteins - metabolism | Drosophila | Humans | Middle Aged | Male | Nuclear Pore - metabolism | Young Adult | Animals | Huntington Disease - genetics | Adult | Female | Mice | Huntingtin Protein - genetics | Mutation | Active Transport, Cell Nucleus - genetics | Induced Pluripotent Stem Cells | Disease Models, Animal | Proteins | Medical colleges | Molecular genetics | Neurons | Analysis | Neurophysiology | Stem cells | Resveratrol | Brain | Animal models | Polyglutamine | Disease | Huntingtin | Macromolecules | Transportation models | Trinucleotide repeats | Agglomeration | Gene expression | Neurotoxicity | Nucleoporins | Neurodegeneration | Aberration | Trinucleotide repeat diseases | Cytoplasm | Apoptosis | Index Medicus | Nuclear Pore Complex | Nucleocytoplasmic Transport | RAN Translation | Induced Pluripotent Stem Cell
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5. Full Text The human TREX-2 complex is stably associated with the nuclear pore basket
by Umlauf, David and Bonnet, Jacques and Waharte, François and Fournier, Marjorie and Stierle, Matthieu and Fischer, Benoit and Brino, Laurent and Devys, Didier and Tora, László
Journal of cell science, ISSN 0021-9533, 06/2013, Volume 126, Issue 12, pp. 2656 - 2667
AMEX | mRNA export | NXF1 | Transcription | Nuclear pore complex | THO/TREX | TREX-2 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA-Binding Proteins - genetics | Acetyltransferases - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Acetyltransferases - genetics | Nuclear Pore Complex Proteins - genetics | Cell Nucleus - metabolism | Exodeoxyribonucleases - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Proto-Oncogene Proteins - metabolism | RNA Transport | Nuclear Pore Complex Proteins - metabolism | RNA, Messenger - genetics | Nuclear Pore - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Nuclear Pore - metabolism | Nucleocytoplasmic Transport Proteins - genetics | Transcription Factors - metabolism | Transcription, Genetic - physiology | Nucleocytoplasmic Transport Proteins - metabolism | Cell Nucleus - genetics | Exodeoxyribonucleases - metabolism | Cell Line, Tumor | HeLa Cells | Transcription, Genetic - genetics | RNA-Binding Proteins - metabolism | Index Medicus
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6. Full Text ER Membrane-Bending Proteins Are Necessary for de novo Nuclear Pore Formation
by T. Renee Dawson and Michelle D. Lazarus and Martin W. Hetzer and Susan R. Wente
The Journal of cell biology, ISSN 0021-9525, 3/2009, Volume 184, Issue 5, pp. 659 - 675
Yeasts | Nuclear pore | Nuclear pore complex proteins | Microscopy | Plasmids | Cell nucleus | Nuclear membrane | Antibodies | P branes | Membrane proteins | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Active Transport, Cell Nucleus - physiology | Saccharomyces cerevisiae - genetics | Nuclear Envelope - ultrastructure | Endoplasmic Reticulum - metabolism | Green Fluorescent Proteins - genetics | Saccharomyces cerevisiae - ultrastructure | Recombinant Fusion Proteins - metabolism | Endoplasmic Reticulum - ultrastructure | Oocytes | Intracellular Membranes - ultrastructure | Saccharomyces cerevisiae - metabolism | Membrane Transport Proteins - genetics | Female | Membrane Transport Proteins - metabolism | Nogo Proteins | Green Fluorescent Proteins - metabolism | Nuclear Envelope - genetics | Xenopus laevis | Nuclear Pore - genetics | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | Nuclear Pore - metabolism | Myelin Proteins - genetics | Nuclear Envelope - metabolism | Animals | Nuclear Pore - ultrastructure | Saccharomyces cerevisiae Proteins - metabolism | Recombinant Fusion Proteins - genetics | Myelin Proteins - metabolism | Intracellular Membranes - metabolism | Physiological aspects | Cell physiology | Research | Properties | Binding proteins | Brewer's yeast | Endoplasmic reticulum | Proteins | Cell division | Membranes | Biochemistry | Yeast | Mutation | Index Medicus
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7. Full Text Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome
by Braun, Daniela A and Sadowski, Carolin E and Kohl, Stefan and Lovric, Svjetlana and Astrinidis, Susanne A and Pabst, Werner L and Gee, Heon Yung and Ashraf, Shazia and Lawson, Jennifer A and Shril, Shirlee and Airik, Merlin and Tan, Weizhen and Schapiro, David and Rao, Jia and Choi, Won-Il and Hermle, Tobias and Kemper, Markus J and Pohl, Martin and Ozaltin, Fatih and Konrad, Martin and Bogdanovic, Radovan and Büscher, Rainer and Helmchen, Udo and Serdaroglu, Erkin and Lifton, Richard P and Antonin, Wolfram and Hildebrandt, Friedhelm
Nature genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 457 - 465
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Cellular proteins | Gene mutations | Development and progression | Nephrotic syndrome | Genetic aspects | Properties | Health aspects | Proteins | Genotype & phenotype | Microscopy | Pathogenesis | Biopsy | Genes | Rodents | Genomics | Mutation | Charitable foundations | Experiments | Index Medicus
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8. Full Text Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans
by Martino, Lisa and Morchoisne-Bolhy, Stéphanie and Cheerambathur, Dhanya K and Van Hove, Lucie and Dumont, Julien and Joly, Nicolas and Desai, Arshad and Doye, Valérie and Pintard, Lionel
Developmental cell, ISSN 1534-5807, 10/2017, Volume 43, Issue 2, pp. 157 - 171.e7
development | Caenorhabditis elegans embryo | nucleoporin | cell division | Polo-like kinase | nuclear envelope breakdown | mitosis | phosphorylation | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Embryo, Nonmammalian - cytology | Phosphorylation | Humans | Embryo, Nonmammalian - metabolism | Caenorhabditis elegans Proteins - metabolism | Nuclear Pore Complex Proteins - genetics | Cell Nucleus - metabolism | Cell Cycle Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Caenorhabditis elegans - metabolism | Nuclear Envelope - genetics | Caenorhabditis elegans - growth & development | Caenorhabditis elegans - genetics | Nuclear Pore Complex Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nuclear Pore - genetics | Proto-Oncogene Proteins - genetics | Nuclear Pore - metabolism | Nuclear Envelope - metabolism | Animals | Cell Nucleus - genetics | Mitosis - physiology | HeLa Cells | Caenorhabditis elegans Proteins - genetics | Cells | Index Medicus | Life Sciences | Development Biology | Cellular Biology | Biochemistry, Molecular Biology
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