X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (46644) 46644
Publication (5538) 5538
Book Review (4822) 4822
Book Chapter (354) 354
Book / eBook (249) 249
Conference Proceeding (115) 115
Newsletter (107) 107
Newspaper Article (42) 42
Dissertation (24) 24
Magazine Article (7) 7
Data Set (4) 4
Government Document (4) 4
Paper (3) 3
Reference (3) 3
Patent (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (41845) 41845
humans (22349) 22349
animals (22171) 22171
biochemistry & molecular biology (12690) 12690
mice (10797) 10797
cell biology (8047) 8047
male (7879) 7879
female (7229) 7229
proteins (7203) 7203
molecular sequence data (6566) 6566
gene expression (6122) 6122
expression (6086) 6086
nuclear proteins - genetics (5191) 5191
nuclear proteins - metabolism (5186) 5186
rats (4947) 4947
cell line (4884) 4884
base sequence (4670) 4670
research (4495) 4495
gene-expression (4463) 4463
analysis (4448) 4448
oncology (4301) 4301
amino acid sequence (4197) 4197
cells, cultured (3901) 3901
physiological aspects (3899) 3899
transcription factors - metabolism (3618) 3618
nuclear proteins - biosynthesis (3577) 3577
genes (3575) 3575
dna-binding proteins - metabolism (3405) 3405
mutation (3325) 3325
article (3278) 3278
transcription, genetic (3269) 3269
signal transduction (3254) 3254
biosynthesis (3229) 3229
protein binding (3215) 3215
transfection (3211) 3211
cells (3205) 3205
protein (3198) 3198
apoptosis (3190) 3190
protein biosynthesis (3169) 3169
cancer (3133) 3133
transcription factors - genetics (3128) 3128
cell line, tumor (3080) 3080
multidisciplinary sciences (3042) 3042
gene expression regulation (3026) 3026
rna, messenger - metabolism (2952) 2952
genetic aspects (2897) 2897
dna-binding proteins - genetics (2836) 2836
phosphorylation (2822) 2822
transcription factors (2818) 2818
immunohistochemistry (2815) 2815
research article (2784) 2784
gene (2753) 2753
cell nucleus - metabolism (2739) 2739
rna, messenger - biosynthesis (2642) 2642
transcription (2638) 2638
metabolism (2637) 2637
activation (2612) 2612
promoter regions, genetic (2604) 2604
rna, messenger - genetics (2549) 2549
biophysics (2546) 2546
biology (2494) 2494
binding sites (2483) 2483
rna (2472) 2472
dna (2445) 2445
middle aged (2357) 2357
genetics & heredity (2344) 2344
adult (2327) 2327
identification (2316) 2316
immunology (2293) 2293
enzymes (2275) 2275
life sciences (2228) 2228
nuclear proteins (2199) 2199
messenger-rna (2153) 2153
medicine (2135) 2135
tumor cells, cultured (2118) 2118
nuclear magnetic resonance--nmr (2072) 2072
blotting, western (2043) 2043
pharmacology & pharmacy (2040) 2040
mice, inbred c57bl (2025) 2025
biochemistry (2011) 2011
endocrinology & metabolism (1979) 1979
plant sciences (1973) 1973
abridged index medicus (1926) 1926
dna-binding proteins - biosynthesis (1926) 1926
reverse transcriptase polymerase chain reaction (1921) 1921
receptors, cytoplasmic and nuclear - metabolism (1912) 1912
hela cells (1884) 1884
cell cycle (1868) 1868
transcription factors - biosynthesis (1868) 1868
in-vivo (1777) 1777
neurosciences (1774) 1774
in-vitro (1737) 1737
saccharomyces-cerevisiae (1736) 1736
aged (1730) 1730
cloning, molecular (1724) 1724
rodents (1715) 1715
science (1692) 1692
liver (1687) 1687
oxidative stress (1661) 1661
binding (1624) 1624
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (174) 174
UofT at Mississauga - Stacks (20) 20
Chemistry (A D Allen) - Stacks (13) 13
UTL at Downsview - May be requested (13) 13
Collection Dvlpm't (Acquisitions) - Closed Orders (12) 12
UofT at Scarborough - Stacks (12) 12
Earth Sciences (Noranda) - Stacks (8) 8
Physics - Stacks (8) 8
Engineering & Comp. Sci. - Stacks (5) 5
Collection Dvlpm't (Acquisitions) - Vendor file (4) 4
Online Resources - Online (4) 4
Gerstein Science - Missing (2) 2
Robarts - Stacks (2) 2
Royal Ontario Museum - Stacks (2) 2
St. Michael's Hospital - Stacks (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reference (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Physics - Storage (1) 1
Regis College - Stacks (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
Toronto East General Hospital - Stacks (1) 1
Trinity College (John W Graham) - Storage (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (46752) 46752
Chinese (234) 234
Russian (78) 78
Japanese (73) 73
German (32) 32
French (27) 27
Spanish (17) 17
Polish (8) 8
Czech (4) 4
Hungarian (3) 3
Italian (3) 3
Arabic (2) 2
Dutch (2) 2
Ukrainian (2) 2
Esperanto (1) 1
Portuguese (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1239 - 1247
The inactivation of the p53 tumor suppressor pathway, which often occurs through mutations in TP53 (encoding tumor protein 53) is a common step in human... 
MEDICINE, RESEARCH & EXPERIMENTAL | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR ACTIVITY | STAPLED P53 | BRAF | MALIGNANT-MELANOMA | P53 PATHWAY | CELL-DEATH | CELL BIOLOGY | BREAST-CANCER | METASTATIC MELANOMA | IN-VIVO | Up-Regulation | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Recombinant Fusion Proteins - physiology | Skin Neoplasms - chemistry | Male | Melanocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - physiology | Cell-Penetrating Peptides - pharmacology | Nuclear Proteins - biosynthesis | Female | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cell Line, Tumor - metabolism | Melanoma - chemistry | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Stem Cell Assay | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - etiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Melanoma, Experimental - genetics | GTP Phosphohydrolases - genetics | Keratinocytes - metabolism | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Nuclear Proteins - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Melanoma | Diagnosis | Research | Gene expression | Identification and classification | Skin cancer | Proteins | Cell growth | Mutation | Cell cycle | Index Medicus
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 10/2010, Volume 17, Issue 10, pp. 1218 - 1225
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 06/2006, Volume 66, Issue 12, pp. 6063 - 6071
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 06/2008, Volume 294, Issue 6, pp. 1119 - 1126
Journal Article
Carcinogenesis, ISSN 0143-3334, 03/2010, Volume 31, Issue 3, pp. 496 - 503
The polycomb group (PcG) proteins are epigenetic regulators of gene expression that enhance cell survival. This regulation is achieved via action of two... 
HISTONE METHYLTRANSFERASE ACTIVITY | SIGNALING PATHWAYS | INCREASED EXPRESSION | DNA METHYLATION | ONCOLOGY | GROUP GENE | PROSTATE-CANCER | DEPENDENT KINASE INHIBITORS | HUMAN KERATINOCYTES | GREEN TEA POLYPHENOL | MAMMARY EPITHELIAL-CELLS | Apoptosis - drug effects | DNA Replication - drug effects | Carcinoma, Squamous Cell - pathology | Cell Count | Humans | Neoplasm Proteins - physiology | Recombinant Fusion Proteins - physiology | Anticarcinogenic Agents - antagonists & inhibitors | Culture Media, Serum-Free | Cell Line, Tumor - drug effects | Cell Line, Transformed - drug effects | Proto-Oncogene Proteins - biosynthesis | Gene Knockdown Techniques | Repressor Proteins - physiology | Nuclear Proteins - biosynthesis | Cell Cycle Proteins - genetics | Epigenesis, Genetic - drug effects | Catechin - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Anticarcinogenic Agents - pharmacology | Cell Line, Transformed - cytology | Skin Neoplasms - pathology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Neoplasm Proteins - biosynthesis | Catechin - antagonists & inhibitors | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Cell Cycle Proteins - biosynthesis | Keratinocytes - cytology | Polycomb-Group Proteins | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Enhancer of Zeste Homolog 2 Protein | Polycomb Repressive Complex 2 | Polycomb Repressive Complex 1 | Repressor Proteins - biosynthesis | Genetic Vectors - pharmacology | Keratinocytes - drug effects | Cell Line, Tumor - cytology | Proto-Oncogene Proteins - physiology | Catechin - analogs & derivatives | Nuclear Proteins - physiology | Cell Cycle Proteins - physiology | DNA-Binding Proteins - biosynthesis | Index Medicus | Cancer Prevention
Journal Article
Nature, ISSN 0028-0836, 12/2010, Volume 468, Issue 7325, pp. 790 - 795
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 12/2012, Volume 10, Issue 12, pp. 1597 - 1606
To understand the mechanisms leading to trastuzumab resistance in HER2-overexpressing breast tumors, we created trastuzumab-insensitive cell lines (SKBR3/100-8... 
MIGRATION | STEM-CELLS | INVASION | GROWTH-FACTOR-RECEPTOR | MECHANISM | LIGANDS | ONCOLOGY | HERCEPTIN | MESENCHYMAL TRANSITION | BETA-CATENIN | CONTRIBUTES | CELL BIOLOGY | Receptor, Epidermal Growth Factor - genetics | Cadherins - metabolism | Receptor, ErbB-2 - genetics | Humans | Transcriptional Activation | Receptor, ErbB-2 - metabolism | Drug Resistance, Neoplasm | Cadherins - biosynthesis | Wnt3 Protein - genetics | Breast Neoplasms - metabolism | Wnt3 Protein - biosynthesis | beta Catenin - biosynthesis | Breast Neoplasms - enzymology | Receptor, Epidermal Growth Factor - metabolism | Nuclear Proteins - biosynthesis | Antibodies, Monoclonal, Humanized - pharmacology | Female | Wnt3 Protein - metabolism | Twist-Related Protein 1 - biosynthesis | Cadherins - genetics | Nuclear Proteins - genetics | Snail Family Transcription Factors | Wnt Signaling Pathway | Receptor, Epidermal Growth Factor - biosynthesis | Receptor, ErbB-2 - biosynthesis | Organic Cation Transport Proteins - metabolism | Nuclear Proteins - metabolism | Transcription Factors - biosynthesis | Transcription Factors - genetics | Organic Cation Transport Proteins - biosynthesis | beta Catenin - metabolism | beta Catenin - genetics | Transcription Factors - metabolism | Phenotype | Breast Neoplasms - genetics | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Organic Cation Transport Proteins - genetics | Twist-Related Protein 1 - metabolism | Trastuzumab | Index Medicus | trastuzumab | β-catenin | EMT | Breast Cancer | Wnt3
Journal Article