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Molecular and Cellular Biology, ISSN 0270-7306, 04/2008, Volume 28, Issue 7, pp. 2426 - 2436
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
INACTIVATION | APOPTOSIS | PROTEIN | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | YAP | SIZE-CONTROL | DIFFERENTIATION | DROSOPHILA | TUMOR-SUPPRESSOR PATHWAY | CELL BIOLOGY | 14-3-3 Proteins - physiology | Phosphorylation | Transferases (Other Substituted Phosphate Groups) - genetics | Humans | Receptor Protein-Tyrosine Kinases - physiology | Recombinant Fusion Proteins - physiology | Transferases (Other Substituted Phosphate Groups) - physiology | Mesoderm - cytology | Drosophila Proteins - physiology | Cell Transdifferentiation - physiology | Membrane Proteins - physiology | Cell Division | c-Mer Tyrosine Kinase | Cell Cycle Proteins - genetics | Conserved Sequence | Transcription, Genetic | Epithelial Cells - cytology | Proteins - physiology | Nerve Tissue Proteins - physiology | Transcription Factors - physiology | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - physiology | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Protein Processing, Post-Translational - physiology | Amino Acid Motifs | Proteins - genetics | Receptor Protein-Tyrosine Kinases - genetics | Cell Transformation, Neoplastic | Proto-Oncogene Proteins - physiology | Cell Line, Tumor | Nuclear Proteins - physiology | Drosophila Proteins - genetics | Cell Cycle Proteins - physiology | Cell Movement | Index Medicus
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2010, Volume 18, Issue 2, pp. 288 - 299
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2011, Volume 30, Issue 4, pp. 770 - 782
Notch signalling is important for development and tissue homeostasis and activated in many human cancers. Nevertheless, mutations in Notch pathway components... 
miR‐200 | ZEB1 | EMT | Notch | stemness | miR-200 | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PHENOTYPE | E-CADHERIN | MIR-200 FAMILY | REPRESSORS ZEB1 | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | COLORECTAL-CANCER | Receptors, Notch - metabolism | Humans | Receptors, Notch - genetics | Gene Knockdown Techniques | Intercellular Signaling Peptides and Proteins - physiology | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Neoplasms - genetics | Membrane Proteins - physiology | Serrate-Jagged Proteins | Base Sequence | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Transcription Factors - physiology | DNA-Binding Proteins - antagonists & inhibitors | Membrane Proteins - genetics | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Models, Biological | Calcium-Binding Proteins - physiology | Homeodomain Proteins - antagonists & inhibitors | Nuclear Proteins - antagonists & inhibitors | Signal Transduction - physiology | MicroRNAs - genetics | Feedback, Physiological - physiology | MicroRNAs - physiology | Homeodomain Proteins - physiology | Calcium-Binding Proteins - genetics | Zinc Finger E-box-Binding Homeobox 1 | Proteins | Signal transduction | Cellular biology | Molecular biology | Gene expression | Cancer | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1239 - 1247
The inactivation of the p53 tumor suppressor pathway, which often occurs through mutations in TP53 (encoding tumor protein 53) is a common step in human... 
MEDICINE, RESEARCH & EXPERIMENTAL | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR ACTIVITY | STAPLED P53 | BRAF | MALIGNANT-MELANOMA | P53 PATHWAY | CELL-DEATH | CELL BIOLOGY | BREAST-CANCER | METASTATIC MELANOMA | IN-VIVO | Up-Regulation | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Recombinant Fusion Proteins - physiology | Skin Neoplasms - chemistry | Male | Melanocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - physiology | Cell-Penetrating Peptides - pharmacology | Nuclear Proteins - biosynthesis | Female | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cell Line, Tumor - metabolism | Melanoma - chemistry | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Stem Cell Assay | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - etiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Melanoma, Experimental - genetics | GTP Phosphohydrolases - genetics | Keratinocytes - metabolism | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Nuclear Proteins - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Melanoma | Diagnosis | Research | Gene expression | Identification and classification | Skin cancer | Proteins | Cell growth | Mutation | Cell cycle | Index Medicus
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 07/2013, Volume 20, Issue 7, pp. 851 - 858
Many Saccharomyces cerevisiae genes encode antisense transcripts, some of which are unstable and degraded by the exosome component Rrp6. Loss of Rrp6 results... 
CRYPTIC UNSTABLE TRANSCRIPTS | PERVASIVE TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERGENIC TRANSCRIPTION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | BIOPHYSICS | BINDING PROTEINS NRD1 | GENE-EXPRESSION | POLY(A) POLYMERASE | POLYMERASE-II TRANSCRIPTS | BIDIRECTIONAL PROMOTERS | RNA DEGRADATION | Saccharomyces cerevisiae - genetics | Multiprotein Complexes | Saccharomyces cerevisiae Proteins - biosynthesis | RNA, Messenger - metabolism | Promoter Regions, Genetic - genetics | RNA, Messenger - biosynthesis | RNA Helicases - physiology | Transcription, Genetic | RNA, Fungal - genetics | Gene Expression Regulation, Fungal | RNA-Binding Proteins - physiology | In Situ Hybridization, Fluorescence | Exosome Multienzyme Ribonuclease Complex - physiology | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Polynucleotide Adenylyltransferase - physiology | Proton-Phosphate Symporters - genetics | RNA, Antisense - metabolism | Polyadenylation | Metalloendopeptidases - physiology | Models, Genetic | Nuclear Proteins - physiology | Saccharomyces cerevisiae Proteins - physiology | Histone Deacetylases - physiology | Proton-Phosphate Symporters - biosynthesis | Histone-Lysine N-Methyltransferase - physiology | DNA Helicases - physiology | RNA, Antisense - genetics | Cytogenetics | Research | Genetic transcription | DNA methylation | Gene expression | Molecular biology | Ribonucleic acid--RNA | Index Medicus | Rrp6 | Nrd1-Nab3-Sen1 | transcription termination | PHO84 regulation | antisense RNA | yeast | single molecule FISH | antisense 3′ end processing
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2010, Volume 18, Issue 2, pp. 309 - 316
Journal Article
Science, ISSN 0036-8075, 2/2008, Volume 319, Issue 5865, pp. 921 - 926
HIV-1 exploits multiple host proteins during infection. We performed a large-scale small interfering RNA screen to identify host factors required by HIV-1 and... 
T lymphocytes | HIV infections | HIV | Cell lines | Small interfering RNA | HeLa cells | Viruses | Infections | Genetic screening | Cells | Research Article | NUCLEAR IMPORT | COMPLEX | TRANSPORT | SNARE TLG1P | N-LINKED GLYCOSYLATION | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | GLYCOPROTEINS | CXCR4 | ENDOPLASMIC-RETICULUM | LATE GOLGI | HIV-1 - pathogenicity | Cytoskeletal Proteins - genetics | Human Immunodeficiency Virus Proteins - physiology | Genomics | Humans | rab GTP-Binding Proteins - genetics | Virus Internalization | Vesicular Transport Proteins - physiology | HIV-1 - physiology | RNA Interference | Transcription, Genetic | Cytoskeletal Proteins - physiology | Mediator Complex | Intracellular Signaling Peptides and Proteins - genetics | Proteins - physiology | HIV Infections - genetics | HIV Infections - virology | Vesicular Transport Proteins - genetics | Computational Biology | HIV-1 - genetics | Virus Integration | Karyopherins - physiology | Host-Pathogen Interactions | rab GTP-Binding Proteins - physiology | Virus Replication | Cell Line, Tumor | Karyopherins - genetics | RNA, Small Interfering | Intracellular Signaling Peptides and Proteins - physiology | HIV Infections - metabolism | Proteins | Gene targeting | RNA | Physiological aspects | Drug targeting | Genetic aspects | Research | Host-virus relationships | Properties | HIV infection | Health aspects | Biomedical research | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 273 - 277
The peroxisomal protein import machinery differs fundamentally from known translocons (endoplasmic reticulum, mitochondria, chloroplasts, bacteria) as it... 
RAT-LIVER | TRANSLOCATION | COMPLEX | INSERTION | CHANNEL | PROTEIN IMPORT | MITOCHONDRIAL INNER MEMBRANE | SACCHAROMYCES-CEREVISIAE | RECEPTOR PEX5P | PREPROTEINS | CELL BIOLOGY | Acyl-CoA Oxidase - metabolism | Protein Transport - physiology | Unilamellar Liposomes - chemistry | Ion Channels - physiology | Porins - analysis | Ubiquitin-Protein Ligases - physiology | Repressor Proteins - analysis | Membrane Proteins - analysis | Membrane Transport Proteins - physiology | Repressor Proteins - physiology | Ion Channel Gating - physiology | Membrane Proteins - physiology | Gene Deletion | Ubiquitin-Protein Ligases - analysis | Peroxins | Saccharomyces cerevisiae - physiology | Peroxisomes - physiology | Electrophysiological Phenomena - physiology | Membrane Transport Proteins - analysis | Membranes, Artificial | Receptors, Cytoplasmic and Nuclear - physiology | Saccharomyces cerevisiae Proteins - genetics | Membrane Potentials - physiology | Saccharomyces cerevisiae - chemistry | Multiprotein Complexes - physiology | Carrier Proteins - genetics | Multiprotein Complexes - chemistry | Models, Biological | Peroxisome-Targeting Signal 1 Receptor | Receptors, Cytoplasmic and Nuclear - analysis | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae Proteins - physiology | Saccharomyces cerevisiae Proteins - analysis | Porins - physiology | Multiprotein Complexes - isolation & purification | Physiological aspects | Cell receptors | Peroxisomes | Cell membranes | Genetic aspects | Research | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 10/2014, Volume 130, Issue 15, pp. 1225 - 1235
BACKGROUND—Atrial fibrillation (AF) affects >30 million individuals worldwide and is associated with an increased risk of stroke, heart failure, and death. AF... 
Atrial fibrillation | Genetics | Zebrafish | Gene expression | Single nucleotide | Epidemiology | Polymorphism | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | VARIANTS | polymorphism | LOCI | epidemiology | atrial fibrillation | PR INTERVAL | genetics | single nucleotide | PERIPHERAL VASCULAR DISEASE | PRAVASTATIN | zebrafish | HEART-RATE | ISCHEMIC-STROKE | gene expression | ONSET | GENOME-WIDE ASSOCIATION | T-Box Domain Proteins - physiology | Humans | Middle Aged | Male | Genetic Loci - physiology | Atrial Fibrillation - physiopathology | Ubiquitin-Protein Ligases - physiology | Gene Knockdown Techniques | Repressor Proteins - physiology | Muscle Proteins | Connexin 43 - physiology | Female | Nuclear Proteins - genetics | Connexin 43 - genetics | Transcription Factors - physiology | Europe | Japan | Repressor Proteins - genetics | Atrial Fibrillation - ethnology | Genotype | Chromosome Mapping | Transcription Factors - genetics | Atrial Fibrillation - genetics | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Zebrafish Proteins - physiology | Animals | Genetic Predisposition to Disease - ethnology | Aged | Nuclear Proteins - physiology | Zebrafish Proteins - genetics | Homeodomain Proteins - physiology | Quantitative Trait Loci | Ubiquitin-Protein Ligases - genetics | Stroke (Disease) | Care and treatment | Usage | Analysis | Genetic transcription | Diagnosis | Nucleotides | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article