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Immunity, ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 463 - 474
Natural helper (NH) cells are innate lymphoid cells (ILCs) that produce T helper-2 (Th2)-cell-type cytokines in the lung- and gut-associated lymphoid tissues.... 
PROGENITORS | CYTOKINES | ROR-GAMMA-T | BONE-MARROW | TYPE-2 IMMUNITY | MICE | INNATE LYMPHOID-CELLS | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Antigens, Ly - genetics | Male | Th2 Cells - immunology | Proto-Oncogene Proteins c-kit - immunology | Interleukin Receptor Common gamma Subunit - immunology | Flow Cytometry | Lymphocytes - immunology | Allergens - immunology | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | Bone Marrow Transplantation | Pneumonia - immunology | Female | Papain - immunology | Proto-Oncogene Proteins c-kit - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Pneumonia - genetics | Lymphocytes - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Nuclear Receptor Subfamily 1, Group F, Member 1 - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Membrane Proteins - immunology | Mice, SCID | Interleukin Receptor Common gamma Subunit - genetics | Th2 Cells - metabolism | Mice, Knockout | Animals | Antigens, Ly - immunology | Mice, Inbred NOD | Mice | Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Allergens | Proteases | Lymphocytes | Oncology, Experimental | Bone marrow | Transplantation | Inflammation | Research | Cancer | Medical research | Lungs | Cytokines | Rodents | Gene expression | Small intestine | Experiments | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 33, pp. 14751 - 14756
In several murine models of autoimmune arthritis, Th17 cells are the dominant initiators of inflammation. In human arthritis the majority of IL-17–secreting... 
T lymphocytes | Synovial fluid | Phenotypes | Cytokines | Juvenile rheumatoid arthritis | Cultured cells | Arthritis | Joint diseases | Joints | T cell antigen receptors | Juvenile | CD161 | RORC2 | RHEUMATOID-ARTHRITIS | GAMMA | MULTIDISCIPLINARY SCIENCES | JUVENILE IDIOPATHIC ARTHRITIS | CD4(+) T-CELLS | INDUCTION | MEMORY CELLS | IL-17 | juvenile | INFLAMED JOINTS | T-H-17 CELLS | LINEAGE | Receptors, CCR6 - immunology | Humans | Interleukin-17 - immunology | Molecular Sequence Data | T-Box Domain Proteins - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Th1 Cells - metabolism | Flow Cytometry | T-Lymphocytes, Helper-Inducer - immunology | Base Sequence | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Receptors, CCR6 - metabolism | Interferon-gamma - genetics | Child | Cell Lineage - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Transforming Growth Factor beta - immunology | Amino Acid Sequence | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Gene Expression | T-Lymphocytes, Helper-Inducer - metabolism | NK Cell Lectin-Like Receptor Subfamily B - metabolism | Interleukin-17 - genetics | Interleukin-12 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Arthritis, Juvenile - genetics | NK Cell Lectin-Like Receptor Subfamily B - immunology | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Arthritis, Juvenile - metabolism | Interleukin-17 - metabolism | NK Cell Lectin-Like Receptor Subfamily B - genetics | Arthritis, Juvenile - immunology | Interferon-gamma - immunology | Interleukin-12 - immunology | Receptors, CCR6 - genetics | Transforming Growth Factor beta - metabolism | Cell Lineage - immunology | Autoimmunity | Research | Adaptation (Physiology) | Genotype & phenotype | Rodents | T cell receptors | Gene expression | Inflammatory diseases | Children & youth | Index Medicus | Animal models | Transcription factors | Helper cells | Interleukin 12 | Interleukin 23 | Inflammation | Lymphocytes T | Transforming growth factor- beta | double prime T-cell receptor | CCR6 protein | Interleukin 17 | Plasticity | Children | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 146 - 160
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 06/2011, Volume 12, Issue 6, pp. 560 - U248
Although the role of the T(H)1 and T(H)17 subsets of helper T cells as disease mediators in autoimmune neuroinflammation remains a subject of some debate, none... 
ENCEPHALOMYELITIS | TGF-BETA | T(H)17 CELLS | COLONY-STIMULATING FACTOR | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | IFN-GAMMA | FACTOR-DEFICIENT MICE | IN-VIVO | IMMUNOLOGY | TH17 CELLS | Peptide Fragments | Encephalomyelitis, Autoimmune, Experimental - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Interleukin-17 - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Th1 Cells - immunology | Th1 Cells - metabolism | Th17 Cells - drug effects | Flow Cytometry | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Th17 Cells - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Female | Interferon-gamma - genetics | Interleukins - pharmacology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Interleukin-12 - pharmacology | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Th1 Cells - drug effects | T-Lymphocytes, Helper-Inducer - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Myelin-Oligodendrocyte Glycoprotein | Mice, Transgenic | Glycoproteins | Mice, Inbred Strains | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-23 - pharmacology | Interferon-gamma - immunology | Th17 Cells - immunology | Mice | Interferon-gamma - pharmacology | Index Medicus
Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 02/2014, Volume 211, Issue 2, pp. 199 - 208
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 02/2014, Volume 134, Issue 2, pp. 366 - 373
Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting has a... 
INFLAMMATORY CYTOKINE RESPONSES | GROWTH-FACTOR-BETA | RETINOIC ACID | T(H)17 CELLS | INTERLEUKIN-17 | CIRCULATING TH17 | DIFFERENTIATION | T-CELLS | AUTOIMMUNE ENCEPHALOMYELITIS | TH17 CELLS | DERMATOLOGY | Gram-Positive Bacterial Infections - immunology | Acne Vulgaris - immunology | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Th1 Cells - immunology | Interleukins - metabolism | Vitamin A - metabolism | CD4-Positive T-Lymphocytes - immunology | Nuclear Receptor Subfamily 1, Group F, Member 1 - metabolism | Receptors, Interleukin - metabolism | Vitamin D - immunology | Interleukins - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Th17 Cells - cytology | Receptors, Interleukin-17 - metabolism | Propionibacterium acnes - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | CD4-Positive T-Lymphocytes - microbiology | Nuclear Receptor Subfamily 1, Group F, Member 1 - immunology | Receptors, Interleukin - immunology | CD4-Positive T-Lymphocytes - cytology | Acne Vulgaris - pathology | Gram-Positive Bacterial Infections - pathology | Cell Differentiation - immunology | Interleukin-17 - metabolism | Th1 Cells - microbiology | Th17 Cells - immunology | Th1 Cells - cytology | Th17 Cells - microbiology | Acne Vulgaris - microbiology | Index Medicus
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 06/2011, Volume 12, Issue 6, pp. 568 - U241
Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) require exposure to IL-23 to become encephalitogenic, but the mechanism by which IL-23 promotes... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | COLONY-STIMULATING FACTOR | ROR-GAMMA-T | INFLAMMATORY RESPONSES | HELPER-CELLS | REGULATORY T-CELLS | IMMUNOLOGY | IL-23 RECEPTOR | TH17 CELLS | CUTTING EDGE | Interleukin-1beta - pharmacology | Peptide Fragments | Encephalomyelitis, Autoimmune, Experimental - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Coculture Techniques | Encephalomyelitis, Autoimmune, Experimental - immunology | Th1 Cells - immunology | CD11c Antigen - immunology | CD11c Antigen - metabolism | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Th17 Cells - drug effects | Flow Cytometry | Interleukin-23 - metabolism | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Th17 Cells - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Antibodies - immunology | Female | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Th1 Cells - drug effects | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Myelin-Oligodendrocyte Glycoprotein | Mice, Transgenic | Glycoproteins | Interleukin-23 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Interleukin-1 - pharmacology | Mice, Knockout | Antibodies - pharmacology | Transforming Growth Factor beta - pharmacology | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-23 - pharmacology | Th17 Cells - immunology | Mice | CD4-Positive T-Lymphocytes - drug effects | Index Medicus
Journal Article
Science, ISSN 0036-8075, 02/2016, Volume 351, Issue 6276, pp. 933 - 939
The SPO11 protein catalyzes the formation of meiotic DNA double strand breaks (DSBs) and is homologous to theAsubunit of an archaeal topoisomerase (topo VI).... 
ROR-GAMMA-T | MULTIDISCIPLINARY SCIENCES | IMMUNE ACTIVATION | SPECTRUM DISORDERS | PROINFLAMMATORY IL-17(+) | DIFFERENTIATION | CEREBRAL-CORTEX | TH17 CELLS | FAMILY | PREGNANCY | HOSPITALIZATION | Interleukin-17 - immunology | Male | Interleukin-17 - pharmacology | Receptors, Retinoic Acid - genetics | Behavior, Animal | RNA, Messenger - biosynthesis | Th17 Cells - drug effects | Receptors, Retinoic Acid - immunology | Female | Cerebral Cortex - drug effects | Cerebral Cortex - abnormalities | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Maternal-Fetal Exchange - immunology | Autism Spectrum Disorder - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Signal Transduction | RNA, Messenger - genetics | Behavioral Symptoms - immunology | Autism Spectrum Disorder - immunology | Interleukin-17 - biosynthesis | Pregnancy | Phenotype | Animals | Prenatal Exposure Delayed Effects - immunology | Cerebral Cortex - immunology | Autism Spectrum Disorder - prevention & control | Antibodies, Blocking - immunology | Antibodies, Blocking - therapeutic use | Th17 Cells - immunology | Mice | Mutation | Autism | Interleukins | Genetic aspects | Observations | Health aspects | Risk factors | Genotype & phenotype | Cytokines | Neurobiology | Prenatal development | Viral infections | Index Medicus
Journal Article