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Protein science, ISSN 0961-8368, 09/2019, Volume 28, Issue 9, pp. 1664 - 1675
emtricitabine | nucleoside reverse transcriptase inhibitors | macromolecular X‐ray crystallography | inhibitor–protein complexes | lamivudine | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | DNA Polymerase gamma - metabolism | Emtricitabine - adverse effects | Humans | Models, Molecular | Reverse Transcriptase Inhibitors - pharmacology | Crystallography, X-Ray | DNA Polymerase gamma - chemistry | Emtricitabine - chemistry | Structure-Activity Relationship | Emtricitabine - pharmacology | Reverse Transcriptase Inhibitors - chemistry | Amino Acid Motifs | Lamivudine - adverse effects | Reverse Transcriptase Inhibitors - adverse effects | HIV Reverse Transcriptase - metabolism | Lamivudine - chemistry | Protein Conformation | Lamivudine - pharmacology | Binding Sites | HIV Reverse Transcriptase - chemistry | Drugs | Emtricitabine | Antiretroviral drugs | RNA-directed DNA polymerase | DNA polymerase | Toxicity | Amino acids | Lamivudine | Mitochondrial DNA | DNA biosynthesis | Highly active antiretroviral therapy | Side effects | Inhibitors | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Nucleosides | Replication | Deoxyribonucleic acid--DNA | DNA-directed DNA polymerase | Crystal structure | Index Medicus | Full‐Length Papers
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2009, Volume 284, Issue 51, pp. 35681 - 35691
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Virus Replication - drug effects | Deoxyadenine Nucleotides - pharmacology | DNA, Viral - biosynthesis | Deoxyadenine Nucleotides - chemistry | Protein Structure, Secondary | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Reverse Transcription - drug effects | Models, Molecular | Reverse Transcriptase Inhibitors - pharmacology | HIV Infections - enzymology | Leukocytes, Mononuclear - virology | Reverse Transcriptase Inhibitors - chemistry | HIV Reverse Transcriptase - metabolism | Hydrophobic and Hydrophilic Interactions | HIV Infections - drug therapy | HIV-1 - enzymology | HIV Reverse Transcriptase - chemistry | Translocation | RNA-directed DNA polymerase | nucleoside reverse transcriptase inhibitors | Hydrophobicity | nucleic acids | DNA biosynthesis | Infection | Molecular modelling | nucleoside analogs | Primers | Antiviral activity | Peripheral blood mononuclear cells | Replication | Elongation | Index Medicus | DNA | Repair, Recombination, and Chromosome Dynamics | Medicin och hälsovetenskap
Journal Article
HIV medicine, ISSN 1464-2662, 10/2020, Volume 21, Issue 9, pp. 599 - 606
protease inhibitors | integrase inhibitors | antiretroviral naïve | nonnucleoside reverse transcriptase inhibitors | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Integrase | Subpopulations | RNA-directed DNA polymerase | Health services | Clinical trials | Proteinase inhibitors | Ribonucleic acid--RNA | Success | Antiretroviral therapy | CD4 antigen | Consortia | Infectious diseases | Immunology | Non-nucleoside reverse transcriptase inhibitors | Protease inhibitors | Acquired immune deficiency syndrome--AIDS | Protease | Antiretroviral agents | Human immunodeficiency virus--HIV | Age | Index Medicus
Journal Article
HIV medicine, ISSN 1464-2662, 11/2008, Volume 9, Issue 10, pp. 883 - 896
etravirine | nonnucleoside reverse transcriptase inhibitor | HIV | resistance | Nonnucleoside reverse transcriptase inhibitor | Resistance | Etravirine | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | HIV Protease Inhibitors - adverse effects | HIV-1 | Drug Administration Schedule | Humans | Middle Aged | Male | CD4 Lymphocyte Count | HIV Protease Inhibitors - administration & dosage | Reverse Transcriptase Inhibitors - administration & dosage | Viral Load | Reverse Transcriptase Inhibitors - adverse effects | Young Adult | Reverse Transcriptase Inhibitors - pharmacokinetics | Epidemiologic Methods | HIV Protease Inhibitors - pharmacokinetics | RNA, Viral | Pyridazines - administration & dosage | Adult | Drug Resistance, Viral - drug effects | Female | HIV Infections - drug therapy | Pyridazines - pharmacokinetics | Antiretroviral Therapy, Highly Active - methods | Pyridazines - adverse effects | Antiviral agents | Medical research | Reverse transcriptase | Protease inhibitors | Proteases | Analysis | Nucleosides | Medicine, Experimental | Reverse transcriptase inhibitors | Universities and colleges | HIV (Viruses) | Anti-HIV agents | Index Medicus
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Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2014, Volume 346, Issue 6212, pp. 1000 - 1003
T lymphocytes | Medical research | Phosphorylation | Transfection | RNA | HEK293 cells | Cell death | REPORTS | Nucleosides | Research grants | Dosage | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Retinal Pigment Epithelium - metabolism | Apoptosis - drug effects | NLR Family, Pyrin Domain-Containing 3 Protein | Reverse Transcriptase Inhibitors - pharmacology | Caspase 1 - metabolism | Geographic Atrophy - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Hepatitis - drug therapy | Animals | Carrier Proteins - metabolism | Choroidal Neovascularization - drug therapy | Graft vs Host Disease - drug therapy | Inflammasomes - drug effects | Liver - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Retinal Pigment Epithelium - physiology | Receptors, Purinergic P2X7 - metabolism | Mice | Reverse Transcriptase Inhibitors - therapeutic use | Alu Elements | Disease Models, Animal | Retinal Pigment Epithelium - drug effects | Prevention | Genetic research | Genetic aspects | Genetic transcription | Research | HIV (Viruses) | Virus research | Macular degeneration | Inhibitor drugs | Drug therapy | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus | Atrophy | Drugs | Inhibitors | Ribonucleic acids | Blocking | Activation | Grafting
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Novel HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent review (2005 - 2010)
Expert opinion on therapeutic patents, ISSN 1354-3776, 05/2011, Volume 21, Issue 5, pp. 717 - 796
inhibitors | AIDS | HIV | drug design | NNRTIs | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Animals | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Drug Design | Drug Resistance, Viral | Reverse Transcriptase Inhibitors - pharmacology | Structure-Activity Relationship | Reverse Transcriptase Inhibitors - therapeutic use | Drug Discovery | Prodrugs - pharmacology | Patents as Topic | Reverse Transcriptase Inhibitors - chemistry | Antiviral agents | Patents | Pharmacodynamics | RNA-directed DNA polymerase | Toxicity | Drug development | Drug resistance | prodrugs | Side effects | Reviews | scaffolds | non-nucleoside reverse transcriptase inhibitors | Antiviral activity | Evolution | Pharmacokinetics | Index Medicus
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 378, Issue 9787, pp. 229 - 237
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | General aspects | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | Rilpivirine | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Middle Aged | Male | Anti-HIV Agents - administration & dosage | Nitriles - administration & dosage | Tenofovir | Deoxycytidine - therapeutic use | Nucleotides - therapeutic use | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Reverse Transcriptase Inhibitors - therapeutic use | Acquired Immunodeficiency Syndrome - virology | Acquired Immunodeficiency Syndrome - ethnology | Emtricitabine | Nucleosides - therapeutic use | Adenine - analogs & derivatives | Benzoxazines - administration & dosage | Double-Blind Method | Drug Administration Schedule | Organophosphonates - therapeutic use | HIV-1 - drug effects | Pyrimidines - administration & dosage | Anti-HIV Agents - adverse effects | Benzoxazines - adverse effects | Treatment Outcome | HIV-1 - genetics | Acquired Immunodeficiency Syndrome - drug therapy | Benzoxazines - therapeutic use | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Mutation | Nitriles - adverse effects | Viral Load - drug effects | Deoxycytidine - analogs & derivatives | Nitriles - therapeutic use | Evaluation | Patient outcomes | Clinical trials | Dosage and administration | Drug therapy | HIV infection | Design | Antiretroviral drugs | Corporate sponsorship | Human immunodeficiency virus--HIV | Technological change | Research | Clinical medicine | Drugs | RNA-directed DNA polymerase | Exanthema | antiretroviral therapy | Lamivudine | Lipids | Nucleotides | Regression analysis | Efavirenz | CD4 antigen | nucleosides | Algorithms | Hospitals | non-nucleoside reverse transcriptase inhibitors | Abacavir | Zidovudine | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of infectious diseases, ISSN 0022-1899, 5/2009, Volume 199, Issue 9, pp. 1275 - 1285
Polymerase chain reaction | Error rates | DNA | Viruses | Stop codon | Genomes | Hepatitis B virus | Genetic mutation | Sequencing | Genotypes | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Microbiology | Biological and medical sciences | Medical sciences | Virology | Humans | DNA, Viral - isolation & purification | Drug Resistance, Viral | Hepatitis B - virology | Genetic Variation | Hepatitis B - complications | Adenine - therapeutic use | Base Sequence | Lamivudine - therapeutic use | Polymerase Chain Reaction | Reverse Transcriptase Inhibitors - therapeutic use | RNA-Directed DNA Polymerase | Adenine - analogs & derivatives | Organophosphonates - therapeutic use | Antiviral Agents - therapeutic use | Genotype | DNA Primers | Hepatitis B virus - drug effects | HIV Infections - complications | Hepatitis B - drug therapy | Hepatitis B virus - genetics | HIV Infections - drug therapy | Hepatitis B virus - isolation & purification | Mutation | DNA, Viral - genetics | Care and treatment | Gene mutations | Nucleosides | Physiological aspects | Genetic aspects | Research | Nucleotide sequencing | Drug resistance | Hepatitis B | Index Medicus | Abridged Index Medicus
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