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1991, Methods in enzymology, ISBN 0121820963, Volume 195, xxx, 512
Book
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e70223
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 01/2012, Volume 51, Issue 1, pp. 194 - 204
Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural... 
RAT-TISSUES | SUBSTRATE-SPECIFICITY | BOVINE LUNG | DEPENDENT PROTEIN-KINASES | ADENYLYL-CYCLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NITRIC-OXIDE | CYTIDINE 3',5'-MONOPHOSPHATE CCMP | PYRIMIDINE NUCLEOTIDES | DIFFERENTIAL INHIBITION | CYTIDYLATE CYCLASE
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2011, Volume 82, Issue 4, pp. 358 - 370
We characterize interactions of 21 (M)ANT-nucleotides with mammalian adenylyl cyclases. Through combination of enzymological, fluorescence spectroscopy and... 
Fluorescence spectroscopy | Conformational landscape | Molecular modelling | Adenylyl Cyclase | MANT-nucleotides | ISOFORMS | PROTEIN | DRUG DISCOVERY | EDEMA FACTOR | DIFFERENTIAL INTERACTIONS | SOLUBLE GUANYLYL CYCLASE | INHIBITION | NUCLEOSIDE 5'-TRIPHOSPHATES | BACILLUS-ANTHRACIS | PHARMACOLOGY & PHARMACY | FORSKOLIN ANALOGS | Cell Line | Catalytic Domain | ortho-Aminobenzoates - chemistry | Pyrimidine Nucleotides - chemistry | Guanosine Triphosphate - analogs & derivatives | Models, Molecular | Spectrometry, Fluorescence | Guanosine Triphosphate - metabolism | Structure-Activity Relationship | Adenylyl Cyclases - metabolism | Mammals | Purine Nucleotides - chemistry | Purine Nucleotides - metabolism | Adenosine Triphosphate - analogs & derivatives | Pyrimidine Nucleotides - metabolism | Spodoptera | Animals | Adenosine Triphosphate - metabolism | Guanosine Triphosphate - chemistry | Adenosine Triphosphate - chemistry | ortho-Aminobenzoates - metabolism | Protein Binding - physiology | Fluorescence | Nucleosides | Pyrimidines | Analysis | Pyrimidine nucleotides | Drugs | Enzymes | Landscape | pharmacophores | Adenine | fluorescence spectroscopy | Nucleotides | Xanthine | Structure-activity relationships | Guanine | Adenylate cyclase | Signal transduction | Ribose | Phosphate | purines | Hypoxanthine | Cytosine | pyrimidines | Uracil | Index Medicus | Life Sciences | Pharmacology | Pharmaceutical sciences | conformational landscape | molecular modeling
Journal Article
Journal Article