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Advances in second messenger and phosphoprotein research, ISSN 1040-7952, 1988
Journal
Cellular signalling, ISSN 0898-6568, 01/2018, Volume 42, pp. 281 - 291
... mechanisms is needed to develop improved drugs. Here, we review the literature to test the hypothesis that a break down in cyclic nucleotide signaling at the level of synthesis, execution, and/or degradation may contribute to these deficits... 
Cerebellum | PDE8 | PDE7 | Mild cognitive impairment | PDE1 | Memory | Cortex | PDE3 | cGMP | Parkinson's Disease | cAMP | Huntington's disease | Striatum | Age-related cognitive decline | Cyclic nucleotides | PDE11 | Aging | Alzheimer's disease | Hippocampus | Phosphodiesterase | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Natriuretic Peptide, Brain - metabolism | Heterotrimeric GTP-Binding Proteins - metabolism | Cyclic GMP-Dependent Protein Kinases - metabolism | Heterotrimeric GTP-Binding Proteins - genetics | Cyclic GMP-Dependent Protein Kinases - genetics | Brain - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Aging - genetics | Guanine Nucleotide Exchange Factors - metabolism | Atrial Natriuretic Factor - genetics | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Guanine Nucleotide Exchange Factors - genetics | Natriuretic Peptide, Brain - genetics | Neurodegenerative Diseases - pathology | Atrial Natriuretic Factor - metabolism | Signal Transduction | Gene Expression Regulation | Neurodegenerative Diseases - genetics | Adenylyl Cyclases - metabolism | Neurodegenerative Diseases - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Cyclic GMP - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Brain - pathology | Adenylyl Cyclases - genetics | Aging - metabolism | Brain | Medical colleges | Neurosciences | Analysis | Cyclic adenylic acid | G proteins | Adenylic acid | Protein kinases | Protein binding | Natriuretic peptides | Index Medicus | Huntington’s Disease | memory | cerebellum | striatum | cyclic nucleotides | Parkinson’s Disease | age-related cognitive decline | cyclase | cortex | PDE5 | Alzheimer’s disease | hippocampus | PDE2 | PDE4 | natriuretic peptide | PDE9 | PDE10 | mild cognitive impairment | aging | phosphodiesterase
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 12/2006, Volume 116, Issue 12, pp. 3240 - 3251
Journal Article