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Genome research, 1995
Journal
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 9, pp. 2343 - 2348
Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants and young children worldwide. The understanding of the molecular... 
Vaccine | Reporter virus | Rotavirus | Reverse genetics | reverse genetics | NSP1 | PROTEIN | MULTIDISCIPLINARY SCIENCES | reporter virus | INNATE IMMUNE-RESPONSE | VACCINIA VIRUS | BLUETONGUE VIRUS | CLONED CDNA | vaccine | MESSENGER-RNA | rotavirus | RNA-CAPPING ENZYME | SYNTHETIC RNA | EXPRESSION | Luciferases - metabolism | Cricetulus | Humans | Methyltransferases - metabolism | Reverse Genetics - methods | DNA, Complementary - genetics | Methyltransferases - genetics | Multienzyme Complexes - metabolism | Green Fluorescent Proteins - genetics | Orthoreovirus - metabolism | Vaccinia virus - genetics | Viral Proteins - metabolism | Luciferases - genetics | Base Sequence | Nucleotidyltransferases - metabolism | Genes, Reporter | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Transduction, Genetic | Vaccinia virus - metabolism | Orthoreovirus - genetics | Orthoreovirus, Mammalian - genetics | Gene Expression Regulation | Viral Nonstructural Proteins - genetics | Viral Proteins - genetics | DNA-Directed RNA Polymerases - genetics | Multienzyme Complexes - genetics | Plasmids - metabolism | Animals | Epithelial Cells - virology | Plasmids - chemistry | Cell Line, Tumor | Nucleotidyltransferases - genetics | Viral Nonstructural Proteins - metabolism | DNA-Directed RNA Polymerases - metabolism | Phosphoric Monoester Hydrolases - metabolism | DNA, Complementary - metabolism | Orthoreovirus, Mammalian - metabolism | Genetic aspects | Gene expression | Health aspects | Rotaviruses | Viruses | Genetics | Microbiology | Pathogenesis | Plasmids | Medical immunity | Index Medicus | Biological Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Index Medicus | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 4, pp. e1003989 - e1003989
Modified vaccinia virus Ankara (MVA) is an attenuated poxvirus that has been engineered as a vaccine against infectious agents and cancers. Our goal is to... 
DOUBLE-STRANDED-RNA | CYCLIC GMP-AMP | KAPPA-B KINASE | COMPLEX CLASS-II | DEPENDENT PROTEIN-KINASE | MICROBIOLOGY | ANTIGEN PRESENTATION | INTERFERON INDUCTION | INTRACELLULAR DNA | VIROLOGY | TOLL-LIKE RECEPTORS | INNATE IMMUNE SENSOR | PARASITOLOGY | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Index Medicus | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19641 - 19646
Journal Article
2002, Molecular biology intelligence unit (Unnumbered), ISBN 0306474379, Volume 22, 421
Book
Journal Article
Molecular Microbiology, ISSN 0950-382X, 01/2010, Volume 75, Issue 2, pp. 268 - 279
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2004, Volume 165, Issue 1, pp. 31 - 40
Understanding gene expression control requires defining the molecular and cellular basis of mRNA turnover. We have previously shown that the human decapping... 
RNA stability | Yeasts | Messenger RNA | HEK293 cells | RNA | Lymphocytes | Plasmids | Cell lines | Cells | Cytoplasm | FRET | Cell cycle | Green fluorescent protein | Transcriptional and translational inhibitors | cell cycle | DEAD BOX HELICASE | NUCLEAR-PROTEIN | green fluorescent protein | MAMMALIAN-CELLS | SACCHAROMYCES-CEREVISIAE | ENDONUCLEOLYTIC CLEAVAGE | CELL BIOLOGY | transcriptional and translational inhibitors | DECAPPING ENZYME | NONSENSE-MEDIATED DECAY | TERMINATION CODONS | SM-LIKE PROTEINS | Endoribonucleases - genetics | Humans | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Organelles - genetics | Organelles - ultrastructure | RNA Interference | Cytoplasmic Granules - metabolism | Membrane Proteins - metabolism | Protein Biosynthesis - genetics | Receptors, Chemokine - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | DEAD-box RNA Helicases | Endoribonucleases - metabolism | Membrane Proteins - genetics | RNA, Messenger - genetics | Receptors, Chemokine - metabolism | Cell Compartmentation - genetics | Intracellular Signaling Peptides and Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | RNA Nucleotidyltransferases - metabolism | RNA Stability - genetics | Proteins - genetics | Proteins - metabolism | Cytoplasmic Granules - ultrastructure | RNA Nucleotidyltransferases - genetics | Cytoplasmic Granules - genetics | Protein Biosynthesis - drug effects | Receptors, CCR4 | Organelles - metabolism | Research | Proteins | Cellular biology | Ribonucleic acid | Fluorescence | Gene expression | Ribonucleic acid--RNA | Index Medicus | cell cycle; FRET; green fluorescent protein; transcriptional and translational inhibitors; RNA stability
Journal Article
Neuron, ISSN 0896-6273, 12/2012, Volume 76, Issue 5, pp. 931 - 944
Precise patterning of axon guidance cue distribution is critical for nervous system development. Using a murine forward genetic screen for novel determinants... 
ALPHA-DYSTROGLYCAN | CONGENITAL MUSCULAR-DYSTROPHY | SLIT | DEFECTIVE GLYCOSYLATION | WALKER-WARBURG-SYNDROME | RECEPTOR | HEPARAN-SULFATE | EXTRACELLULAR-MATRIX | NEUROSCIENCES | BRAIN | MIDLINE | Protein Binding - genetics | Embryo, Mammalian | Alkaline Phosphatase - metabolism | Glycoproteins - metabolism | Cercopithecus aethiops | Gene Expression Regulation, Developmental - genetics | N-Acetylglucosaminyltransferases - genetics | Neurons - cytology | Central Nervous System - embryology | Amino Acids - metabolism | Transfection | N-Acetylglucosaminyltransferases - deficiency | Neural Cell Adhesion Molecule L1 - metabolism | Nucleotidyltransferases - metabolism | Dystroglycans - physiology | Glycoproteins - genetics | Alkaline Phosphatase - genetics | Mice, Inbred C57BL | Axons - metabolism | Models, Molecular | Mice, Transgenic | Glycosylation | Mutation - genetics | Nerve Tissue Proteins - genetics | Body Patterning - physiology | Nerve Tissue Proteins - metabolism | Animals | Central Nervous System - cytology | Nucleotidyltransferases - genetics | Dystroglycans - genetics | Mice | Laminin - metabolism | Neurofilament Proteins - metabolism | Receptors, Immunologic - genetics | Body Patterning - genetics | COS Cells | Receptors, Immunologic - metabolism | Neurosciences | Analysis | Proteins | Ligands | Spinal cord | Mutation | Insects | Defects | Index Medicus | Dystroglycan | Alternation learning | Floor plate | Slit protein | Nervous system | Robo protein | Basement membranes | Axon guidance | Genetic screening
Journal Article
Journal Article