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INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 06/2008, Volume 122, Issue 11, pp. 2429 - 2436
O-6 -methylguanine-DNA methyltransferase (MGMT) is a DNA repair gene which is frequently methylated in colorectal cancer (CRC). However, it remains... 
CANCER-CELLS | PROMOTER HYPERMETHYLATION | WILD-TYPE | colorectal cancer | MICROSATELLITE INSTABILITY | CPG ISLAND | adenomatous polyps | A-T TRANSITIONS | O-6 -methylguanine-DNA methyltransferase | promoter methylation | K-RAS | ONCOLOGY | KRAS mutations | G-C | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE | EXPRESSION
Journal Article
Journal of Cancer Research and Therapeutics, ISSN 0973-1482, 2016, Volume 12, Issue 8, pp. C233 - C236
Journal Article
NEUROLOGY INDIA, ISSN 0028-3886, 03/2011, Volume 59, Issue 2, pp. 229 - 235
Assessment of promoter methylation of the O-6-methylguanine DNA methyltransferase (MGMT) gene has recently gained importance in molecular profiling of... 
HYPERMETHYLATION | SURVIVAL BENEFIT | NEWLY-DIAGNOSED GLIOBLASTOMA | Glioblastoma | PHASE-II | NEUROSCIENCES | ADJUVANT TEMOZOLOMIDE | O-6-methylguanine DNA methyltransferase | MGMT GENE | CONCOMITANT | glioma | PROGNOSTIC-SIGNIFICANCE | RADIOTHERAPY | EXPRESSION
Journal Article
Journal of Oral Pathology & Medicine, ISSN 0904-2512, 09/2010, Volume 39, Issue 8, pp. 645 - 650
J Oral Pathol Med (2010) 39: 645–650 Background:  O 6‐methylguanine‐DNA methyltransferase (MGMT) is a specific DNA direct reversal repair protein which... 
O6‐methylguanine‐DNA methyltransferase | polymorphisms | methylguanine-DNA methyltransferase | VARIANTS | GENOTYPE | DNA-REPAIR GENES | MGMT PROMOTER METHYLATION | HUMAN O-6-METHYLGUANINE-DNA METHYLTRANSFERASE | PATHOLOGY | O6-methylguanine-DNA methyltransferase | LUNG-CANCER | COLORECTAL-CANCER | DENTISTRY, ORAL SURGERY & MEDICINE | SQUAMOUS-CELL CARCINOMA | O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | ASSOCIATION | Gene Frequency - genetics | Age Factors | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Male | Case-Control Studies | Haplotypes - genetics | Female | Cytosine | Retrospective Studies | Codon - genetics | Leucine - genetics | Mouth Neoplasms - genetics | Genetic Predisposition to Disease - genetics | Risk Factors | Thymine | Linkage Disequilibrium - genetics | Genotype | Survival Rate | Precancerous Conditions - genetics | Sequence Analysis, DNA | Disease-Free Survival | O-Methylguanine-DNA Methyltransferase - genetics | Phenylalanine - genetics | Taiwan | Polymorphism, Single Nucleotide - genetics | Polymorphism, Genetic - genetics | Genetic Variation - genetics | Haplotypes | Statistical analysis | Linkage disequilibrium | oral squamous cell carcinoma | Gene polymorphism | Survival | Pathology | DNA | Carcinogenicity | Codons | Lesions | Stratification | Genotypes | Cancer | DNA sequencing
Journal Article
Journal Article
BIOCHEMICAL PHARMACOLOGY, ISSN 0006-2952, 06/2008, Volume 75, Issue 11, pp. 2100 - 2111
Journal Article
by Park, TJ and Han, SU and Cho, YK and Paik, WK and Kim, YB and Lim, IK
CANCER, ISSN 0008-543X, 12/2001, Volume 92, Issue 11, pp. 2760 - 2768
BACKGROUND. O-6-methylguanine-DNA, methyltransferase (MGMT) can remove O(6)alkylG DNA adducts. If they are not removed, then the adducts mispair with T during... 
PROMOTER HYPERMETHYLATION | AMPLIFICATION MASA | CELLS | POINT MUTATION | survival | CANCER | K-ras mutation | tumor stage | P53 MUTATIONS | INACTIVATION | REPAIR | O-6-methylguanine DNA methyltransferase methylation | ONCOLOGY | DNA | O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | gastric carcinoma
Journal Article
Brain Pathology, ISSN 1015-6305, 10/2008, Volume 18, Issue 4, pp. 520 - 532
Silencing of O6-methylguanine-DNA methyltransferase (MGMT) protein expression because of MGMT gene promoter hypermethylation is considered to be associated... 
glioblastoma | immunohistochemistry | biomarker | MGMT | prognosis | Immunohistochemistry | Biomarker | Prognosis | Glioblastoma | METHYLATION ANALYSIS | PROMOTER HYPERMETHYLATION | MISMATCH REPAIR | PATHOLOGY | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE GENE | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN-TUMORS | DNA-DAMAGING AGENTS | INTERLABORATORY VALIDATION | O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | MALIGNANT GLIOMAS | INTEROBSERVER REPRODUCIBILITY | Antibody Specificity | Predictive Value of Tests | Glioblastoma - enzymology | Prospective Studies | Humans | Middle Aged | Brain Neoplasms - physiopathology | DNA Repair Enzymes - genetics | Antibodies | Promoter Regions, Genetic - genetics | DNA Methylation | Tumor Suppressor Proteins - genetics | DNA Repair Enzymes - metabolism | Biomarkers, Tumor - metabolism | Adult | DNA Modification Methylases - analysis | Brain Neoplasms - enzymology | Diagnosis, Differential | Reproducibility of Results | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Glioblastoma - diagnosis | Biomarkers, Tumor - analysis | Brain Neoplasms - diagnosis | Survival Rate | DNA Repair Enzymes - analysis | Immunohistochemistry - methods | DNA Modification Methylases - genetics | Aged | Glioblastoma - physiopathology | Observer Variation | Cohort Studies | Tumor Suppressor Proteins - analysis | Algorithms | Methylation | Glioblastoma multiforme | Patient outcomes
Journal Article
by Wu, ZL and Zhang, J and Cheng, H and Liang, P and Guo, YH and Yan, Z and Zhao, JR
DIAGNOSTIC MOLECULAR PATHOLOGY, ISSN 1052-9551, 12/2010, Volume 19, Issue 4, pp. 232 - 235
O-6-Methylguanine-DNA methyltransferase methylation status has a very good predictive value for benefit from alkylating agent therapy. The stratified therapy... 
OLIGONUCLEOTIDE PROBES | GLIOBLASTOMA | O-6-Methylguanine-DNA methyltransferase | HYPERMETHYLATION | methylation | fluorescence polarization | PATHOLOGY | CANCER
Journal Article
ONCOLOGY REPORTS, ISSN 1021-335X, 11/2005, Volume 14, Issue 5, pp. 1275 - 1280
Journal Article
by Qi, J and Zhu, YQ and Huang, MF and Yang, D
WORLD JOURNAL OF GASTROENTEROLOGY, ISSN 1007-9327, 04/2005, Volume 11, Issue 13, pp. 2022 - 2025
AIM: To investigate the functions of promoter hypermethylation of O-6-methylguanine-DNA methyltransferase (MGMT) gene in colorectal tumorigenesis and... 
Epigenetic change | DNA methylation | O-6-methylguanine-DNA methyltransferase | CpG island | GASTROENTEROLOGY & HEPATOLOGY | K-ras mutation
Journal Article
Journal Article