X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (823) 823
Book Review (60) 60
Publication (52) 52
Book Chapter (7) 7
Dissertation (5) 5
Conference Proceeding (4) 4
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
o6-methylguanine-dna methyltransferase (680) 680
index medicus (415) 415
oncology (353) 353
humans (320) 320
temozolomide (247) 247
dna methylation (238) 238
glioblastoma (210) 210
dna methyltransferase (208) 208
dna repair (205) 205
deoxyribonucleic acid--dna (192) 192
methylation (192) 192
cancer (188) 188
methylguanine (187) 187
tumors (170) 170
o-6-methylguanine-dna methyltransferase (165) 165
chemotherapy (150) 150
alkylating-agents (149) 149
female (149) 149
male (144) 144
dna (139) 139
mgmt (139) 139
expression (126) 126
middle aged (123) 123
survival (121) 121
glioblastoma multiforme (115) 115
biochemistry & molecular biology (112) 112
dna modification methylases - genetics (109) 109
adult (106) 106
tumor suppressor proteins - genetics (106) 106
dna repair enzymes - genetics (105) 105
aged (104) 104
gene expression (102) 102
o-6-alkylguanine-dna alkyltransferase (101) 101
repair (100) 100
animals (96) 96
escherichia-coli (92) 92
prognosis (91) 91
dacarbazine - analogs & derivatives (89) 89
glioma (88) 88
patients (83) 83
transferases (82) 82
neoplasms (81) 81
brain tumors (79) 79
mutation (78) 78
radiotherapy (78) 78
methylguanine-dna methyltransferase (75) 75
o-methylguanine-dna methyltransferase - genetics (74) 74
genetics & heredity (73) 73
analysis (70) 70
promoter regions, genetic (70) 70
immunohistochemistry (68) 68
polymerase chain reaction (67) 67
apoptosis (65) 65
promoter methylation (65) 65
brain neoplasms - genetics (64) 64
medical prognosis (64) 64
brain cancer (62) 62
clinical neurology (62) 62
gene (62) 62
gliomas (61) 61
medicine (61) 61
genes (60) 60
glioblastoma - genetics (60) 60
mice (60) 60
alkylation (59) 59
dna damage (59) 59
o-methylguanine-dna methyltransferase - metabolism (59) 59
research (59) 59
cell line, tumor (58) 58
multidisciplinary sciences (58) 58
radiation therapy (57) 57
surgery (57) 57
proteins (56) 56
aged, 80 and over (55) 55
dna modification methylases - metabolism (54) 54
toxicology (54) 54
tumor suppressor proteins - metabolism (53) 53
brain neoplasms - drug therapy (52) 52
cell biology (52) 52
dna repair enzymes - metabolism (52) 52
protein (52) 52
hypermethylation (51) 51
alkylating agents (50) 50
drug resistance (50) 50
o-methylguanine-dna methyltransferase (50) 50
o6-methylguanine dna methyltransferase (50) 50
cancer therapies (49) 49
mismatch repair (49) 49
research article (49) 49
adjuvant temozolomide (48) 48
medicine & public health (48) 48
dacarbazine - therapeutic use (47) 47
genetic aspects (47) 47
brain neoplasms - pathology (46) 46
deoxyribonucleic acid (46) 46
mammalian-cells (46) 46
biomarkers (45) 45
care and treatment (45) 45
human o6-methylguanine-dna methyltransferase (45) 45
science (45) 45
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Neuropathology and Applied Neurobiology, ISSN 0305-1846, 02/2018, Volume 44, Issue 2, pp. 172 - 184
Aims: It is important to predict response to treatment with temozolomide (TMZ) in glioblastoma (GBM) patients. Both MGMT protein expression and MGMT promoter... 
glioblastoma multiforme | O‐6‐methylguanine–DNA methyltransferase | glioma | MGMT | image analysis | prognosis | O-6-methylguanine–DNA methyltransferase | SURVIVAL | PROMOTER METHYLATION | O-6-methylguanine-DNA methyltransferase | PATHOLOGY | MULTIFORME | NEUROSCIENCES | CLINICAL NEUROLOGY | ADJUVANT TEMOZOLOMIDE | HETEROGENEITY | POOR-PROGNOSIS | CONCOMITANT | RADIOTHERAPY | IMMUNOHISTOCHEMISTRY | Prognosis | Humans | Middle Aged | O-Methylguanine-DNA Methyltransferase - metabolism | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Male | Survival Rate | Brain Neoplasms - metabolism | O-Methylguanine-DNA Methyltransferase - genetics | Glioblastoma - genetics | Glioblastoma - pathology | Female | Glioblastoma - metabolism | Aged | Brain Neoplasms - mortality | Glioblastoma - mortality | Medical research | Analysis | Transferases | DNA | Genetic research | Medicine, Experimental | Methylation | Glioblastoma multiforme | Methylguanine | Glioblastoma | Radiation therapy | O6-methylguanine-DNA methyltransferase | Studies | Proteins | Medical prognosis | DNA methylation | DNA methyltransferase | Protein expression | Temozolomide | Immunofluorescence | Tumors | Index Medicus | Clinical Medicine | Clinical Laboratory Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | glioblastoma multiforme; glioma; image analysis; MGMT; O-6-methylguanine-DNA methyltransferase; prognosis | Klinisk medicin | Klinisk laboratoriemedicin
Journal Article
Cancer, ISSN 0008-543X, 04/2018, Volume 124, Issue 7, pp. 1316 - 1318
Methylation of the promoter region of the O 6 ‐methylguanine DNA methyltransferase ( MGMT ) gene has emerged as the first—and so far the only—predictive... 
Methylguanine | Glioblastoma | Pharmacology | Chemical compounds | Alkylation | O6-methylguanine-DNA methyltransferase | Chemotherapy | DNA methylation | Biomarkers | DNA methyltransferase | Bioindicators | Temozolomide | Methylation | Deoxyribonucleic acid--DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e74466 - e74466
Glioblastoma multiforme (GBM) is one of the most deadly types of cancer. To date, the best clinical approach for treatment is based on administration of... 
OVEREXPRESSION | GLIOBLASTOMA | PROMOTER METHYLATION | MULTIDISCIPLINARY SCIENCES | MALIGNANT GLIOMAS | MICE | MICRORNAS | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE | CANCER | TUMORIGENESIS | ADJUVANT TEMOZOLOMIDE | DNA Damage - drug effects | Humans | RNA, Messenger - genetics | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Antineoplastic Agents, Alkylating - pharmacology | Apoptosis - genetics | Glioma - metabolism | Glioma - genetics | DNA Modification Methylases - genetics | Drug Resistance, Neoplasm - genetics | RNA Interference | Dacarbazine - pharmacology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Cell Line, Tumor | DNA Damage - genetics | MicroRNAs - genetics | Temozolomide | MicroRNA | Gliomas | Cell death | DNA damage | Transferases | DNA | Genetic aspects | Methylation | Cancer | Biotechnology | Brain tumors | Glioblastoma | mRNA | Kinases | Chromosome rearrangements | Cancer therapies | DNA repair | Alkylation | O6-methylguanine-DNA methyltransferase | Proteins | Rodents | Glioma cells | Penicillin | DNA methylation | Tumorigenesis | Damage | Deoxyribonucleic acid--DNA | Enzymes | Methylguanine | MiRNA | Cell division | Radiation therapy | Forensic medicine | Gene expression | Patients | Glioblastoma multiforme | Pathology | Ribonucleic acids | MicroRNAs | Medical prognosis | Regulatory mechanisms (biology) | Epigenetics | DNA methyltransferase | Chromosome aberrations | Tumors | Apoptosis | Index Medicus | Càncer | Glioma | ADN | Micro RNAs | Deoxyribonucleic acid
Journal Article
BBA - Reviews on Cancer, ISSN 0304-419X, 12/2011, Volume 1816, Issue 2, pp. 179 - 190
-Methylguanine-DNA methyltransferase (MGMT) is a suicide enzyme that repairs the pre-mutagenic, pre-carcinogenic and pre-toxic DNA damage -methylguanine. It... 
Promoter methylation | Alkyltransferase | Drug resistance | MGMT | DNA repair | O6-methylguanine-DNA methyltransferase | methylguanine-DNA methyltransferase
Journal Article
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, ISSN 0304-419X, 12/2011, Volume 1816, Issue 2, pp. 179 - 190
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 12/2011, Volume 102, Issue 12, pp. 2186 - 2190
Glioblastoma multiforme (GBM) is the most frequently occurring primary malignant brain tumor; patients with GBM often have a very poor prognosis and differing... 
PATHWAYS | SURVIVAL | ANAPLASTIC ASTROCYTOMA | CELLS | ONCOLOGY | CONCOMITANT | MGMT PROMOTER METHYLATION | SUPPRESSES TUMORIGENICITY | RADIOTHERAPY | MICRORNA-21 | ADJUVANT TEMOZOLOMIDE | Prognosis | Humans | Middle Aged | DNA Repair Enzymes - genetics | Male | Brain Neoplasms - metabolism | DNA Methylation | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | DNA Repair Enzymes - metabolism | Biomarkers, Tumor - metabolism | Adult | Female | Glioblastoma - metabolism | Retrospective Studies | Brain Neoplasms - mortality | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Glioblastoma - diagnosis | Brain Neoplasms - diagnosis | Kaplan-Meier Estimate | Brain Neoplasms - genetics | MicroRNAs - biosynthesis | Treatment Outcome | Disease-Free Survival | DNA Modification Methylases - genetics | Aged | Biomarkers, Tumor - genetics | Glioblastoma - mortality | MicroRNA | Brain tumors | Patient outcomes | Immunotherapy | Transferases | Genes | Development and progression | Universities and colleges | Methylation | Gene expression | Glioblastoma multiforme | Post-transcription | glioblastoma multiforme | Melting | non-coding RNA | biomarkers | Glioblastoma | Data processing | Survival | Promoters | Risk factors | O6-methylguanine-DNA methyltransferase | Surgery | DNA methylation | miRNA | Cancer | Index Medicus
Journal Article