UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
oatp1b1 (201) 201
science & technology (162) 162
life sciences & biomedicine (159) 159
humans (133) 133
pharmacology & pharmacy (122) 122
solute carrier organic anion transporter family member 1b1 (75) 75
organic anion transporters - genetics (69) 69
male (62) 62
organic anion transporters - metabolism (57) 57
drug interactions (49) 49
pharmacokinetics (44) 44
female (41) 41
oatp1b3 (41) 41
animals (39) 39
adult (35) 35
genotype (35) 35
slco1b1 (35) 35
pharmacogenetics (33) 33
liver - metabolism (32) 32
pharmacology (27) 27
polymorphism, single nucleotide (27) 27
organic anion transporters - antagonists & inhibitors (24) 24
toxicology (24) 24
cell line (23) 23
middle aged (23) 23
statins (23) 23
hek293 cells (22) 22
pharmacology/toxicology (22) 22
transporter (22) 22
polymorphism (21) 21
solute carrier organic anion transporter family member 1b3 (21) 21
analysis (20) 20
biochemistry & molecular biology (20) 20
biomedicine (20) 20
hepatocytes - metabolism (20) 20
kinetics (20) 20
liver (20) 20
area under curve (19) 19
chemistry (19) 19
organic anion transporters, sodium-independent - metabolism (18) 18
organic anion transporting polypeptide (18) 18
physical sciences (18) 18
genetic aspects (17) 17
hydroxymethylglutaryl-coa reductase inhibitors - pharmacokinetics (17) 17
polymorphism, genetic (17) 17
pravastatin (17) 17
biological transport (16) 16
pharmacy (16) 16
research (15) 15
biochemistry, general (14) 14
drug-drug interaction (14) 14
metabolites (14) 14
polypeptides (14) 14
bcrp (13) 13
chemistry, multidisciplinary (13) 13
genetic polymorphisms (13) 13
haplotypes (13) 13
liver-specific organic anion transporter 1 (13) 13
oncology (13) 13
rosuvastatin (13) 13
dose-response relationship, drug (12) 12
genetics & heredity (12) 12
mrp2 (12) 12
physiological aspects (12) 12
transporters (12) 12
young adult (12) 12
aged (11) 11
biotechnology & applied microbiology (11) 11
cytochrome p450 (11) 11
drug metabolism (11) 11
drug-drug interactions (11) 11
enzymes (11) 11
hepatocytes - drug effects (11) 11
medicine, research & experimental (11) 11
models, biological (11) 11
research & experimental medicine (11) 11
simvastatin (11) 11
complications and side effects (10) 10
drugs (10) 10
gene expression (10) 10
hypoglycemic agents - pharmacokinetics (10) 10
pharmaceutical preparations - metabolism (10) 10
pharmacogenomics (10) 10
pravastatin - pharmacokinetics (10) 10
proteins (10) 10
rosuvastatin calcium (10) 10
transfection (10) 10
administration, oral (9) 9
atorvastatin (9) 9
atp-binding cassette transporters - genetics (9) 9
bilirubin (9) 9
biomedical engineering (9) 9
cytochrome p-450 (9) 9
drug interaction (9) 9
genetic variation (9) 9
health aspects (9) 9
liver - drug effects (9) 9
medical law (9) 9
metabolism (9) 9
organic anion transporters, sodium-independent - antagonists & inhibitors (9) 9
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (208) 208
Chinese (14) 14
Japanese (6) 6
Russian (2) 2
Czech (1) 1
German (1) 1
Korean (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Oncology reports, ISSN 1021-335X, 08/2017, Volume 38, Issue 2, pp. 1124 - 1132
Overexpression lentivirus platform was established of OATP1B1 (organic anion transporting polypeptides 1B1) wild-type and mutant type genetic polymorphism in... 
Endoxifen | OATP1B1-OATP1B1 521T>C | Tamoxifen | OATP1B1 388A>G | Life Sciences & Biomedicine | Oncology | Science & Technology | Tamoxifen - metabolism | Biological Transport | Humans | HEK293 Cells | Tamoxifen - analogs & derivatives | Polymorphism, Genetic | Solute Carrier Organic Anion Transporter Family Member 1b1 - genetics
Journal Article
Journal of hepatology, ISSN 0168-8278, 01/2013, Volume 58, Issue 1, pp. 155 - 168
Summary Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation where BAs exert their multiple physiological functions... 
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Pharmaceutical research, ISSN 1573-904X, 11/2012, Volume 30, Issue 3, pp. 761 - 780
To apply physiologically-based pharmacokinetic (PBPK) modeling to investigate the consequences of reduction in activity of hepatic and intestinal uptake and... 
Biochemistry, general | Biomedical Engineering | cyclosporine | drug-drug interactions | Biomedicine | Pharmacy | OATP1B3 | Medical Law | Pharmacology/Toxicology | physiologically-based pharmacokinetic models | OATP1B1 | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Intestines - drug effects | Intestinal Mucosa - metabolism | Organic Anion Transporters - antagonists & inhibitors | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Enzyme Inhibitors - metabolism | Cyclosporine - pharmacology | Humans | Liver - metabolism | Enzyme Inhibitors - pharmacology | Organic Anion Transporters - metabolism | Cytochrome P-450 CYP3A Inhibitors | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Liver - drug effects | Cytochrome P-450 CYP3A - metabolism | Models, Biological | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | Cyclosporine - pharmacokinetics | Liver-Specific Organic Anion Transporter 1 | Cyclosporine - metabolism | Solute Carrier Organic Anion Transporter Family Member 1B3 | Complications and side effects | Metabolites | Drug interactions | Cytochrome P-450 | Drugstores | Models | Physicians (General practice) | Cyclosporine | Side effects | Pharmacology | Kinetics | Index Medicus
Journal Article
Pharmaceutical research, ISSN 0724-8741, 2/2012, Volume 29, Issue 2, pp. 411 - 426
Journal Article
Cancer biology & therapy, ISSN 1555-8576, 10/2014, Volume 12, Issue 9, pp. 780 - 787
Journal Article
Cancer chemotherapy and pharmacology, ISSN 1432-0843, 10/2018, Volume 83, Issue 1, pp. 107 - 113
Journal Article
Pharmaceutical research, ISSN 1573-904X, 12/2014, Volume 32, Issue 6, pp. 1864 - 1883
To develop a population physiologically-based pharmacokinetic (PBPK) model for simvastatin (SV) and its active metabolite, simvastatin acid (SVA), that allows... 
Biochemistry, general | Biomedical Engineering | drug-drug interactions | Biomedicine | Pharmacy | PBPK | simvastatin | Medical Law | population model | Pharmacology/Toxicology | OATP1B1 | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Activation, Metabolic | Cytochrome P-450 Enzyme Inhibitors - therapeutic use | Simvastatin - adverse effects | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Biological Availability | Muscle, Skeletal - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemistry | Healthy Volunteers | Simvastatin - blood | Organic Anion Transporters - metabolism | Tissue Distribution | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Drug Interactions | Liver - drug effects | Muscle, Skeletal - drug effects | Muscular Diseases - chemically induced | Pharmacogenetics | Reproducibility of Results | Simvastatin - chemistry | Muscular Diseases - metabolism | Simvastatin - administration & dosage | Liver - metabolism | Simvastatin - pharmacokinetics | Simvastatin - analogs & derivatives | Polymorphism, Genetic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Models, Biological | Solute Carrier Organic Anion Transporter Family Member 1b1 | Metabolites | Simvastatin | Drug interactions | Liver | Cytochrome P-450 | Antilipemic agents | Side effects | Pharmacology | Kinetics | Statins | Index Medicus
Journal Article