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Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
European journal of clinical pharmacology, ISSN 0031-6970, 6/2006, Volume 62, Issue 6, pp. 409 - 415
SLCO1B1 | Pharmacogenetics | Haplotype | OATP1B1 | Polymorphism | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Haplotypes | European Continental Ancestry Group - genetics | Gene Frequency | Humans | Genotype | Male | DNA Primers - genetics | Linkage Disequilibrium | Organic Anion Transporters - genetics | Base Sequence | Alleles | Finland | Female | Polymorphism, Single Nucleotide | Solute Carrier Organic Anion Transporter Family Member 1b1 | Index Medicus
Journal Article
British journal of pharmacology, ISSN 0007-1188, 10/2009, Volume 158, Issue 3, pp. 693 - 705
repaglinide | SLCO1B1 | organic anion transporting polypeptide | statin | transporter | simvastatin | OATP | OATP1B1 | pharmacogenetics | Organic anion transporting polypeptide | Pharmacogenetics | Simvastatin | Repaglinide | Statin | Transporter | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Organic Anion Transporters, Sodium-Independent - genetics | Peptides - physiology | Humans | Liver - metabolism | Intestinal Absorption | Blood-Brain Barrier - metabolism | Genetic Variation | Organic Anion Transporters - genetics | Pharmaceutical Preparations - metabolism | Drug Interactions | Organic Anion Transporters - physiology | Pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Solute Carrier Organic Anion Transporter Family Member 1B3 | Organic Anion Transporters, Sodium-Independent - physiology | Index Medicus | Reviews
Journal Article
Journal of clinical pharmacology, ISSN 0091-2700, 11/2012, Volume 52, Issue 11, pp. 1725 - 1738
SLCO1B1 | Darunavir | pravastatin | drug‐drug interaction | OATP1B1 | ritonavir | drug-drug interaction | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Haplotypes | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Ritonavir - administration & dosage | Cholesterol - blood | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Middle Aged | Male | HIV Protease Inhibitors - administration & dosage | Polymorphism, Genetic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Pravastatin - blood | Organic Anion Transporters - genetics | Drug Interactions | Pravastatin - administration & dosage | Triglycerides - blood | Adult | Female | Solute Carrier Organic Anion Transporter Family Member 1b1 | Pravastatin - pharmacokinetics | Sulfonamides - administration & dosage | Measurement | Research | Pravastatin | Analysis | Genetic polymorphisms | Antiretroviral drugs | Index Medicus
Journal Article
Journal of clinical pharmacology, ISSN 0091-2700, 03/2008, Volume 48, Issue 3, pp. 311 - 321
SLCO1B1 | Repaglinide | nateglinide | pharmacogenetics | OATP1B1 | Pharmacogenetics | Nateglinide | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cytochrome P-450 CYP2C9 | Cytochrome P-450 CYP2C8 | Phenylalanine - analogs & derivatives | Tablets | Area Under Curve | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Half-Life | Metabolic Clearance Rate | Carbamates - pharmacokinetics | Carbamates - chemistry | Piperidines - blood | Dose-Response Relationship, Drug | Hypoglycemic Agents - blood | Tandem Mass Spectrometry | Organic Anion Transporters - genetics | Phenylalanine - chemistry | Chromatography, Liquid | Cyclohexanes - chemistry | Piperidines - pharmacokinetics | Molecular Structure | Pharmacogenetics - methods | Hypoglycemic Agents - pharmacokinetics | Piperidines - chemistry | Carbamates - blood | Genotype | Hypoglycemic Agents - chemistry | Cyclohexanes - blood | Phenylalanine - pharmacokinetics | Analysis of Variance | Phenylalanine - blood | Polymorphism, Single Nucleotide | Blood Glucose - metabolism | Cyclohexanes - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Dosage and administration | Research | Properties | Pharmacokinetics | Index Medicus
Journal Article