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1. Full Text Human Study on the Kinetics of 2′R‐Ochratoxin A in the Blood of Coffee Drinkers
by Sueck, Franziska and Cramer, Benedikt and Czeschinski, Peter and Humpf, Hans‐Ulrich
Molecular Nutrition & Food Research, ISSN 1613-4125, 02/2019, Volume 63, Issue 4, p. n/a
Scope The aim of this study is to obtain a deeper knowledge of the kinetics of 2′R‐ochratoxin A (2′R‐OTA), the thermal degradation product of the mycotoxin... 
ochratoxin A | 2′R‐ochratoxin A | human study | blood | coffee | 2′R-ochratoxin A | IMMUNOAFFINITY COLUMN CLEANUP | SPOTS | FOOD SCIENCE & TECHNOLOGY | ADULTS | SERUM | BIOMARKERS | OCHRATOXIN-A | 2 ' R-ochratoxin A | URINE | EXPOSURE
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2. Full Text Matrix binding of ochratoxin a during roasting
by Bittner, Andrea and Cramer, Benedikt and Humpf, Hans-Ulrich
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 12/2013, Volume 61, Issue 51, pp. 12737 - 12743
The mycotoxin ochratoxin A is degraded during coffee roasting by up to 90%. During this process, the two known degradation products, 14R-ochratoxin A and... 
bound mycotoxins | 14 R -ochratoxin A | coffee | roasting | ochratoxin A saccharide ester | enzymatic cleavage | masked mycotoxins | Ochratoxin A | ochratoxin A ester | ACID | ASPERGILLUS-OCHRACEUS | FOOD SCIENCE & TECHNOLOGY | ENZYMATIC-HYDROLYSIS | 14R-ochratoxin A | CELL-WALLS | IN-VITRO | PENICILLIUM | COFFEE BEANS | POLYSACCHARIDES | AGRICULTURE, MULTIDISCIPLINARY | DEGRADATION | CHEMISTRY, APPLIED | CELLULOSE | Ochratoxins - chemistry | Coffea - chemistry | Seeds - chemistry | Cooking | Hot Temperature | Food Contamination - analysis
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3. Full Text Ochratoxin a: Molecular interactions, mechanisms of toxicity and prevention at the molecular level
by Kőszegi, Tamás and Poór, Miklós
Toxins, ISSN 2072-6651, 04/2016, Volume 8, Issue 4, p. 111
Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health risks. The focus of the present review is on the molecular and cellular... 
Albumin binding | Prevention | Toxicokinetics | Flavonoids | Nephropathy | Cellular effects | Ochratoxin A | CELLS IN-VITRO | HUMAN SERUM-ALBUMIN | FOOD SCIENCE & TECHNOLOGY | 2'-DEOXYGUANOSINE-CARBON 8-BOUND OCHRATOXIN | toxicokinetics | cellular effects | C8-DEOXYGUANOSINE NUCLEOSIDE ADDUCT | COVALENT DNA ADDUCTION | OXIDATIVE STRESS RESPONSES | BALKAN ENDEMIC NEPHROPATHY | ANION-TRANSPORTING POLYPEPTIDE | nephropathy | TOXICOLOGY | URINARY-TRACT TUMORS | flavonoids | CHRONIC INTERSTITIAL NEPHROPATHY | prevention | albumin binding | Animals | Diet | Albumins - metabolism | Food Contamination | Humans | Ochratoxins - chemistry | Ochratoxins - pharmacokinetics | Protective Agents - therapeutic use | Ochratoxins - toxicity
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4. Full Text Some major mycotoxins and their mycotoxicoses—An overview
by Richard, John L
International Journal of Food Microbiology, ISSN 0168-1605, 2007, Volume 119, Issue 1, pp. 3 - 10
Mycotoxins likely have existed for as long as crops have been grown but recognition of the true chemical nature of such entities of fungal metabolism was not... 
T-2 toxins | Ochratoxin | Trichothecenes | Fumonisins | Mycotoxins | Aflatoxin(s) | Zearalenone | Deoxynivalenol | Mycotoxicoses | Ergot | aflatoxin(s) | zearalenone | mycotoxins | FUSARIUM-MONILIFORME | FOOD SCIENCE & TECHNOLOGY | CONIDIA | MICROBIOLOGY | deoxynivalenol | OCHRATOXIN-A | DUST | ochratoxin | fumonisins | ergot | trichothecenes | mycotoxicoses | Aflatoxins - chemistry | Mycotoxins - chemistry | Humans | Food Handling - methods | Ochratoxins - chemistry | Ergot Alkaloids - chemistry | Fungi - metabolism | Mycotoxins - toxicity | Ochratoxins - toxicity | Mycotoxins - biosynthesis | Food Contamination - prevention & control | Edible Grain - microbiology | Trichothecenes - toxicity | Animals | Ergot Alkaloids - toxicity | Mycotoxicosis - diagnosis | Trichothecenes - chemistry | Edible Grain - chemistry | Aflatoxins - toxicity | Analysis | Plant metabolites
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5. Full Text Identification and safety evaluation of a product from the biodegradation of ochratoxin A by an Aspergillus strain
by Xiong, Ke and Wang, Xiao‐ling and Zhi, Hui‐Wei and Sun, Bao‐Guo and Li, Xiu‐Ting
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 01/2017, Volume 97, Issue 2, pp. 434 - 443
BACKGROUND Ochratoxin A (OTA) poses a serious health hazard throughout the world and is often reported in food commodities. At present, biological approaches... 
cytotoxic responses | degradation product | ochratoxin A | ochratoxin α | Aspergillus strain | IMMUNOAFFINITY COLUMN CLEANUP | CELLS | DETOXIFICATION | APOPTOSIS | BACTERIA | FOOD SCIENCE & TECHNOLOGY | HYDROLYSIS | SUPPRESSION | ochratoxin | AGRICULTURE, MULTIDISCIPLINARY | DEGRADATION | HUMAN BLOOD | CHEMISTRY, APPLIED | MYCOTOXINS | Biodegradation, Environmental | Ochratoxins - adverse effects | Food Contamination | Humans | Ochratoxins - isolation & purification | Solubility | Ochratoxins - metabolism | Food Microbiology | Agriculture | DNA Damage | Decontamination - methods | Lipid Peroxidation | Aspergillus niger - metabolism | Superoxide Dismutase | Biodegradation | Physiological aspects | Biological products | Safety and security measures | Fungi | Toxins | Food safety | Food contamination & poisoning | Degradation | Aspergillus niger | Health hazards | Sod | Lipids | Foods | Damage | Product safety
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6. Full Text Ochratoxin A: 50 years of research
by Malir, Frantisek and Ostry, Vladimir and Pfohl-Leszkowicz, Annie and Malir, Jan and Toman, Jakub
Toxins, ISSN 2072-6651, 07/2016, Volume 8, Issue 7, p. 191
Since ochratoxin A (OTA) was discovered, it has been ubiquitous as a natural contaminant of moldy food and feed. The multiple toxic effects of OTA are a real... 
Urothelial cancer | Toxicity | Biomarkers | Balkan endemic nephropathy | Carcinogenicity | Microfungi | Ochratoxin A | Feed | Food | toxicity | ochratoxin A | LINKED-IMMUNOSORBENT-ASSAY | biomarkers | FOOD SCIENCE & TECHNOLOGY | 2'-DEOXYGUANOSINE-CARBON 8-BOUND OCHRATOXIN | urothelial cancer | THIN-LAYER CHROMATOGRAPHY | TANDEM MASS-SPECTROMETRY | DNA ADDUCT FORMATION | IN-VITRO CYTOTOXICITY | food | carcinogenicity | PERFORMANCE LIQUID-CHROMATOGRAPHY | feed | microfungi | HUMAN PROXIMAL TUBULE | TOXICOLOGY | CHRONIC INTERSTITIAL NEPHROPATHY | Kidney Neoplasms - genetics | History, 21st Century | Kidney - pathology | Humans | Kidney Neoplasms - chemically induced | Balkan Nephropathy - chemically induced | Cell Transformation, Neoplastic - chemically induced | Kidney Neoplasms - metabolism | Ochratoxins - metabolism | Toxicology - history | Balkan Nephropathy - history | Kidney - metabolism | Cell Transformation, Neoplastic - genetics | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Balkan Nephropathy - genetics | Food Microbiology - history | Kidney - drug effects | Ochratoxins - history | Risk Assessment | Balkan Nephropathy - metabolism | History, 20th Century | Risk Factors | Toxicology - trends | Cell Transformation, Neoplastic - metabolism | Food Microbiology - trends | Ochratoxins - toxicity | Animals | Kidney Neoplasms - history | DNA Damage | Oxidative Stress - drug effects
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7. Full Text Ochratoxin a and mitotic disruption: Mode of action analysis of renal tumor formation by ochratoxin A
by Mally, Angela
Toxicological Sciences, ISSN 1096-6080, 2012, Volume 127, Issue 2, pp. 315 - 330
The mycotoxin and food contaminant ochratoxin A (OTA) is a potent renal carcinogen in rodents, but its mode of action (MoA) is still poorly defined. In 2006,... 
Mitosis | Carcinogenesis | Ochratoxin A | MoA | ochratoxin A | HISTONE ACETYLTRANSFERASES | OXIDATIVE DNA-DAMAGE | URINARY-BLADDER | MYCOTOXIN OCHRATOXIN | mitosis | GENDER DIFFERENCE | IN-VITRO | carcinogenesis | MESSENGER-RNA | HUMAN PROXIMAL TUBULE | SALMONELLA-TYPHIMURIUM | TOXICOLOGY | NEPHROTOXIN OCHRATOXIN | Genomic Instability | Kidney Neoplasms - genetics | Kidney Tubules, Proximal - pathology | Ochratoxins - adverse effects | Risk Assessment | Food Contamination | Humans | Kidney Neoplasms - chemically induced | Risk Factors | Cell Transformation, Neoplastic - chemically induced | Ochratoxins - metabolism | Dose-Response Relationship, Drug | Animals | Mitosis - drug effects | Time Factors | Cell Transformation, Neoplastic - genetics | Kidney Tubules, Proximal - metabolism | Kidney Neoplasms - pathology | Cell Transformation, Neoplastic - pathology | Kidney Tubules, Proximal - drug effects | Index Medicus
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8. Full Text Biosynthesis of ochratoxins by Aspergillus ochraceus
by Harris, Jonathan P and Mantle, Peter G
Phytochemistry, ISSN 0031-9422, 2001, Volume 58, Issue 5, pp. 709 - 716
Shaken liquid fermentation of an isolate of Aspergillus ochraceus showed growth-associated production of ochratoxins A and B, followed by production of a... 
Aspergillus ochraceus | Ochratoxin B | Ochratoxin β | Ochratoxin A | Ochratoxin α | Shaken solid substrate fermentation | Pulse-radiolabeling | Mellein | Ethionine | PIGS | ochratoxin A | pulse-radiolabeling | ochratoxin B | shaken solid substrate fermentation | BIOCHEMISTRY & MOLECULAR BIOLOGY | STATE | ochratoxin alpha | ochratoxin beta | PLANT SCIENCES | mellein | ethionine | Aspergillus ochraceus - growth & development | Ochratoxins - biosynthesis | Fermentation - physiology | Pyrones - metabolism | Carbon Radioisotopes - analysis | Aspergillus ochraceus - metabolism | Isocoumarins
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9. Full Text Mycotoxins: Occurrence, toxicology, and exposure assessment
by Marin, S and Ramos, A.J and Cano-Sancho, G and Sanchis, V
Food and Chemical Toxicology, ISSN 0278-6915, 10/2013, Volume 60, pp. 218 - 237
Mycotoxins are abiotic hazards produced by certain fungi that can grow on a variety of crops. Consequently, their prevalence in plant raw materials may be... 
Toxicology | Exposure | Occurrence | Mycotoxins | Food | NEURAL-TUBE DEFECTS | FOOD SCIENCE & TECHNOLOGY | ESTROGENIC MYCOTOXIN | AFLATOXIN B-1 | HEALTH-RISK ASSESSMENT | DIETARY EXPOSURE | OCHRATOXIN-A | EUKARYOTIC PROTEIN-SYNTHESIS | URINARY DEOXYNIVALENOL | FUSARIUM MYCOTOXINS | CATALONIA SPAIN | Zearalenone - analysis | Food Contamination - analysis | Consumer Product Safety | Humans | Ochratoxins - analysis | Environmental Exposure - analysis | Fumonisins - toxicity | Mycotoxins - toxicity | Food Microbiology | Fumonisins - analysis | Ochratoxins - toxicity | Trichothecenes - analysis | Zearalenone - toxicity | Trichothecenes - toxicity | Animals | Aflatoxins - analysis | Aflatoxins - toxicity | Index Medicus
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10. Full Text Human ochratoxin A biomarkers-From exposure to effect
by Duarte, Sofia Cancela and Pena, Angelina and Lino, Celeste Matos
Critical Reviews in Toxicology, ISSN 1040-8444, 3/2011, Volume 41, Issue 3, pp. 187 - 212
Ochratoxin A (OTA) is a nephrotoxic mycotoxin that has received particular attention because of the toxic effects, widespread occurrence in contaminated food... 
ochratoxin A | biomonitoring | exposure | urine | Assessment | effect | milk | DNA adducts | biomarker | blood | β2-microglobulin | HUMAN PLASMA | BREAST-MILK SAMPLES | MYCOTOXINS OCHRATOXIN | COVALENT DNA ADDUCTION | PERFORMANCE LIQUID-CHROMATOGRAPHY | BALKAN ENDEMIC NEPHROPATHY | beta-microglobulin | HUMAN-BLOOD | FLUORESCENCE DETECTION | TOXICOLOGY | HUMAN URINE | RISK-ASSESSMENT | Biomarkers - metabolism | Dose-Response Relationship, Drug | Biomarkers - urine | Poisons - toxicity | Poisons - chemistry | Poisons - metabolism | Humans | Ochratoxins - chemistry | Biomarkers - blood | Environmental Exposure - analysis | Ochratoxins - metabolism | Ochratoxins - toxicity
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11. Full Text Human Study on the Kinetics of 2'R-Ochratoxin A in the Blood of Coffee Drinkers
by Sueck, Franziska and Cramer, Benedikt and Czeschinski, Peter and Humpf, Hans-Ulrich
Molecular nutrition & food research, ISSN 1613-4125, 02/2019, Volume 63, Issue 4, p. e1801026
The aim of this study is to obtain a deeper knowledge of the kinetics of 2'R-ochratoxin A (2'R-OTA), the thermal degradation product of the mycotoxin... 
Coffee - chemistry | Ochratoxins - urine | Ochratoxins - blood | Stereoisomerism | Humans | Half-Life | Ochratoxins - chemistry | Adult | Female | Male |