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Journal Article
Human Mutation, ISSN 1059-7794, 12/2017, Volume 38, Issue 12, pp. 1684 - 1699
Journal Article
Neuroscience Letters, ISSN 0304-3940, 05/2018, Volume 675, pp. 116 - 119
Mitochondrial dysfunction, oxidative stress and energy production have been implicated in the etiology of Parkinson’s disease (PD). Several agents are under... 
SLC22A5 gene | OCTN2 | Parkinson’s disease | Faroe Islands | Carnitine
Journal Article
Expert Opinion on Therapeutic Targets, ISSN 1472-8222, 08/2018, Volume 22, Issue 8, pp. 715 - 726
Introduction: Transporters in the plasma membrane have been exploited successfully for the delivery of drugs in the form of prodrugs and nanoparticles. Organic... 
nanoparticles | L-carnitine | drug delivery | biological barriers | OCTN2 | prodrugs | oral absorption | ACETYL-L-CARNITINE | ALZHEIMERS-DISEASE | CANCER-CELL-LINES | FUNCTIONAL-CHARACTERIZATION | CATION TRANSPORTER | BLOOD-BRAIN-BARRIER | IN-VITRO | GAMMA-BUTYROBETAINE | PHARMACOLOGY & PHARMACY | OCTN2 SLC22A5 | HEPATIC-ENCEPHALOPATHY
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2019, Volume 115, Issue 8, pp. 1296 - 1305
Aims Heart failure is characterized by structural and metabolic cardiac remodelling. The aim of the present study is to expand our understanding of the complex... 
Heart failure | CARDIAC & CARDIOVASCULAR SYSTEMS | TRANSPORTER | HEART-FAILURE | CARDIOMYOPATHY | Biomarkers | GENE-TRANSFER | Metabolism | OCTN2 | EXPRESSION | Therapeutic target
Journal Article
Pediatric Reports, ISSN 2036-749X, 2018, Volume 10, Issue 2, pp. 39 - 42
Systemic primary carnitine deficiency (SPCD) is an autosomal recessive inborn error of fatty acid metabolism caused by a defect in the transporter responsible... 
SLC22A5 | Dilated cardiomyopathy | OCTN2 | Systemic primary carnitine deficiency | Systemic Primary Carnitine Deficiency, SLC22A5, Dilated Cardiomyopathy, OCTN2
Journal Article
Toxicology Letters, ISSN 0378-4274, 11/2019, Volume 316, pp. 183 - 193
Olanzapine, a representative of antipsychotics, is a first-line drug for treatment of schizophrenia. However, olanzapine-induced liver steatosis limits its... 
Olanzapine | OCTN2 | FATPs | Carnitine | Liver steatosis | PROTEIN | CYP3A4 | METABOLISM | GENE | DISEASE | SREBPS | TOXICOLOGY | WEIGHT | EXPRESSION | INSIGHTS
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2012, Volume 134, Issue 1, pp. 101 - 115
Journal Article
Pulmonary Pharmacology and Therapeutics, ISSN 1094-5539, 02/2012, Volume 25, Issue 1, pp. 124 - 134
Background: The aim of the present investigation was to compare the pulmonary absorption of the novel long-acting β -agonist GW597901 with salbutamol and to... 
Methacholine | GW597901 | Salbutamol | OCTN2 | Pulmonary absorption | Carnitine
Journal Article
BRITISH JOURNAL OF NUTRITION, ISSN 0007-1145, 06/2019, Volume 121, Issue 12, pp. 1323 - 1333
While strong evidence from clinical studies suggests beneficial effects of carnitine supplementation on metabolic health, serious safety concerns associated... 
Liver | CARDIOMYOPATHY | TRANSPORTER OCTN2 | ENDOPLASMIC-RETICULUM STRESS | Skeletal muscle | DEFICIENCY | Aged mice | NUTRITION & DIETETICS | FATTY-ACID OXIDATION | BIOSYNTHESIS | Carnitine supplementation | GAMMA-BUTYROBETAINE | QUALITY-OF-LIFE | ACCUMULATION | EXPRESSION
Journal Article