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Journal Article
GENOME BIOLOGY, ISSN 1474-760X, 01/2019, Volume 20, Issue 1, pp. 14 - 14
Genome engineering methods have advanced greatly with the development of programmable nucleases, but methods for quantifying on- and off-target cleavage sites... 
INTEGRATION | HIV | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | OFF-TARGET CLEAVAGE | BREAKS | GENETICS & HEREDITY | REARRANGEMENTS | SEQUENCING REVEALS | GENOME | CRISPR | Chromatin | Pipelines | DNA damage | T cell receptors | Genomes | Design | Lymphocytes | Immunotherapy | Fragile sites | Stem cells | Software | Binding sites | Deoxyribonucleic acid--DNA | Methods | Index Medicus
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2019, Volume 116, Issue 18, pp. 8693 - 8698
Journal Article
Cell Reports, ISSN 2211-1247, 01/2018, Volume 22, Issue 2, pp. 372 - 382
Journal Article
Bioinformatics, ISSN 1367-4803, 09/2018, Volume 34, Issue 18, pp. 3069 - 3077
Abstract Motivation CRISPR/Cas9 system is a widely used genome editing tool. A prediction problem of great interests for this system is: how to select optimal... 
HUMAN-CELLS | BIOCHEMICAL RESEARCH METHODS | CRISPR-CAS9 | GUIDE RNAS | OFF-TARGET | MODELS | DATABASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SGRNA DESIGN | SELECTION | CAS NUCLEASES
Journal Article
Nature, ISSN 0028-0836, 04/2018, Volume 556, Issue 7699, pp. 57 - 63
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 03/2019, Volume 10, Issue 1, pp. 1133 - 12
Genome editing for therapeutic applications often requires cleavage within a narrow sequence window. Here, to enable such high-precision targeting with... 
CONTROLLING GENE-EXPRESSION | MESSENGER-RNA | DNA RECOGNITION | MULTIDISCIPLINARY SCIENCES | OFF-TARGET CLEAVAGE | INITIATION CODON | SELECTION | DIRECTED EVOLUTION | BINDING | T-CELLS | HEMATOPOIETIC STEM | Proteins | Nucleotide sequence | Fingers | Therapeutic applications | Editing | Design factors | Cleavage | Genomes | Dimers | Zinc finger proteins | Loci | Zinc | Index Medicus
Journal Article