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Structure, ISSN 0969-2126, 04/2018, Volume 26, Issue 4, pp. 649 - 656.e3
We describe the comparative X-ray structural analysis of three Anticalin proteins directed against the extra-domain B (ED-B) of oncofetal fibronectin (Fn), a... 
structural plasticity | lipocalin 2 | X-ray structure analysis | fibronectin | extra-domain B | non-Ig scaffold | ONCOFETAL FIBRONECTIN | EXTRA-DOMAIN B | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYSTAL-STRUCTURES | BINDING-PROTEINS | ANTIBODY FRAGMENTS | CELL BIOLOGY | BIOPHYSICS | ED-B | AFFINITY | MOLECULAR RECOGNITION | CRYPTIC SEQUENCE | Epitopes - metabolism | Lipocalin-2 - chemistry | Humans | Peptides - genetics | Crystallography, X-Ray | Structure-Activity Relationship | Peptide Library | Antigens, Neoplasm - chemistry | Peptides - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Protein Engineering | Antigens, Neoplasm - metabolism | Lipocalin-2 - genetics | Protein Interaction Domains and Motifs | Binding Sites | Recombinant Proteins - metabolism | Amino Acid Sequence | Antigens, Neoplasm - genetics | Protein Conformation, alpha-Helical | Gene Expression | Genetic Vectors - chemistry | Peptides - chemistry | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Epitopes - genetics | Fibronectins - metabolism | Sequence Homology, Amino Acid | Sequence Alignment | Lipocalin-2 - metabolism | Fibronectins - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Protein Binding | Epitopes - chemistry | Fibronectins - genetics | Fibronectins | Antigens | Analysis | Tumors | Antigenic determinants
Journal Article
Trends in Parasitology, ISSN 1471-4922, 2018, Volume 35, Issue 3, pp. 178 - 181
Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to be shared between placental trophoblasts and cancer cells and can... 
VAR2CSA | cancer | oncofetal chondroitin sulfate | placental malaria | CHONDROITIN SULFATE | PLASMODIUM-FALCIPARUM | PARASITOLOGY | Plasmodium falciparum | Glycosaminoglycans | Malaria | Sulfates | Cancer | Protein binding
Journal Article
Advances In Anatomic Pathology, ISSN 1072-4109, 11/2014, Volume 21, Issue 6, pp. 450 - 460
Glypican 3 is a membrane-bound heparan sulfate proteoglycan, which has recently been identified as a marker for liver cancer and germ cell malignancies.... 
Immunohistochemistry | Testicular cancer | Oncofetal protein | Yolk sac tumor | SQUAMOUS-CELL | DIFFERENTIAL-DIAGNOSIS | GERM-CELL TUMORS | GOLABI-BEHMEL-SYNDROME | oncofetal protein | FIBROBLAST-GROWTH-FACTOR | PATHOLOGY | testicular cancer | yolk sac tumor | CLEAR-CELL | GASTRIC-CARCINOMA | immunohistochemistry | YOLK-SAC TUMOR | HUMAN HEPATOCELLULAR-CARCINOMA | ALPHA-FETOPROTEIN | Predictive Value of Tests | Genetic Testing | Prognosis | Humans | Ovarian Neoplasms - pathology | Glypicans - analysis | Male | Neoplasms, Germ Cell and Embryonal - genetics | Liver Neoplasms - chemistry | Neoplasms, Germ Cell and Embryonal - blood | Glypicans - blood | Neoplasms, Germ Cell and Embryonal - diagnosis | Testicular Neoplasms - pathology | Neoplasms, Germ Cell and Embryonal - chemistry | Liver Neoplasms - blood | Ovarian Neoplasms - genetics | Carcinoma, Hepatocellular - genetics | Female | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - chemistry | Carcinoma, Hepatocellular - blood | Testicular Neoplasms - diagnosis | Ovarian Neoplasms - chemistry | Testicular Neoplasms - genetics | Liver Neoplasms - genetics | Biomarkers, Tumor - analysis | Carcinoma, Hepatocellular - diagnosis | Ovarian Neoplasms - diagnosis | Ovarian Neoplasms - blood | Glypicans - genetics | Biomarkers, Tumor - blood | Liver Neoplasms - diagnosis | Biopsy | Carcinoma, Hepatocellular - pathology | Biomarkers, Tumor - genetics | Testicular Neoplasms - chemistry | Testicular Neoplasms - blood | Neoplasms, Germ Cell and Embryonal - pathology
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2014, Volume 191, Issue 3, pp. 830 - 841
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2016, Volume 138, Issue 5, pp. 1269 - 1280
The standard of care for diagnosis and therapy monitoring of gliomas is magnetic resonance imaging (MRI), which however, provides only an indirect and... 
protein scaffold | protein engineering | brain tumor diagnosis | molecular imaging tracer | oncofetal fibronectin | lipocalin | immunohistochemistry | ANGIOGENESIS | BEVACIZUMAB | MARKER | ANTIBODY | TUMORS | NEUROONCOLOGY | TEMOZOLOMIDE | HIGH-GRADE | ONCOLOGY | EXPRESSION | BRAIN | Immunohistochemistry | Lipocalins - metabolism | Protein Structure, Tertiary | Brain Neoplasms - chemistry | Antibodies - metabolism | Fibronectins - analysis | Glioblastoma - diagnosis | Brain Neoplasms - diagnosis | Humans | Platelet Endothelial Cell Adhesion Molecule-1 - analysis | Molecular Imaging - methods | Peptide Library | Fibronectins - metabolism | Lipocalins - immunology | Cell Line, Tumor | Protein Binding | Glioblastoma - chemistry | Fibronectins | Tracers (Biology) | Gliomas | Imaging systems | Diagnostic imaging | Diagnosis | Binding proteins | Protein binding | Studies | Nuclear magnetic resonance--NMR | Tumors | Neuroimaging | Slopes | Brain | Therapy | Brain tumors | Brain cancer | Glioblastoma | Fibronectin | Proteins | Angiogenesis | Design engineering | Quality | Imaging | Classification | Extracellular matrix | Matrix protein | Localization | Monitoring | Binding | Immunoglobulins | Lipocalin | Magnetic resonance | Histology | Patients | Glioblastoma multiforme | Autoradiography | Magnetic resonance imaging | Antiangiogenics | Reagents | Diagnostic software | Affinity | Resonance | Diagnostic systems | Position (location) | Combinatorial analysis | Cytofluorometry | Tracers
Journal Article
Experimental Biology and Medicine, ISSN 1535-3702, 7/2014, Volume 239, Issue 7, pp. 842 - 852
There is an increasing biotechnological interest in the ‘arming’ of therapeutic antibodies with bioactive payloads. While many antibody–cytokine fusion... 
chemokine | armed antibody | vascular targeting | oncofetal fibronectin | Immunochemokine | antibody-chemokine fusion protein | MEDICINE, RESEARCH & EXPERIMENTAL | DEPENDENT ANTITUMOR RESPONSES | ANGIOGENESIS | EXPERIMENTAL SOLID TUMORS | CANCER-THERAPY | MATRIX METALLOPROTEINASES | CXC CHEMOKINE | INTERFERON-GAMMA | IMMUNOTHERAPY | IN-VIVO | FIBRONECTIN
Journal Article