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Oncogene, ISSN 1476-5594, 2012, Volume 32, Issue 22, pp. 2767 - 2781
.... Here, we show that c-Kit is not just a marker of OTICs, but also a critical mediator of the phenotype that can be a viable target for the treatment of ovarian cancer... 
b-catenin | chemoresistance | c-Kit | ovarian cancer | ABCG2 | beta-catenin | SURFACE EPITHELIUM | ONCOLOGY-GROUP | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLATINUM-RESISTANT | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY | PHASE-II TRIAL | ONCOLOGY | SEROUS CARCINOMA | GENETICS & HEREDITY | IMATINIB MESYLATE | EPITHELIAL OVARIAN | CLINICOPATHOLOGICAL FEATURES | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Paclitaxel - pharmacology | Neoplastic Stem Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Tumor Microenvironment | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Wnt Proteins - metabolism | Cell Hypoxia | Neoplastic Stem Cells - metabolism | RNA Interference | Cell Transformation, Neoplastic - genetics | ATP-Binding Cassette Transporters - metabolism | Female | Proto-Oncogene Proteins c-kit - genetics | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Ovarian Neoplasms - metabolism | Ovarian Neoplasms - drug therapy | Cell Survival - drug effects | Cisplatin - pharmacology | Pyrimidines - pharmacology | Cell Transformation, Neoplastic - metabolism | Imatinib Mesylate | Piperazines - pharmacology | beta Catenin - metabolism | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Wnt Signaling Pathway - drug effects | Mice, Nude | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 4044 - 4054
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 03/2012, Volume 110, Issue 5, pp. 701 - 715
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2007, Volume 129, Issue 43, pp. 12926 - 12927
..., but not duplex DNA, and exhibit potential for discriminating between DNA quadruplexes. Cell-based experiments using cell lines that express the proto-oncogene c-kit (MCF-7 and HGC-27... 
TELOMERIC DNA | RECOGNITION | MYC | TRANSCRIPTION | PROMOTER REGION | PROTOONCOGENE | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Surface Plasmon Resonance | Flavins - chemistry | G-Quadruplexes | Ligands | Proto-Oncogene Proteins c-kit - genetics | Gene Expression | Vitamin B2 | Ligand binding (Biochemistry) | Research | Gene expression
Journal Article