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1. Full Text Oncolytic virotherapy
by Russell, Stephen J and Peng, Kah-Whye and Bell, John C
Nature Biotechnology, ISSN 1087-0156, 07/2012, Volume 30, Issue 7, pp. 658 - 670
Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Recent advances include preclinical proof... 
TUMOR-SPECIFIC DEFECTS | MEDIATED GENE-EXPRESSION | HERPES-SIMPLEX-VIRUS | INTRATUMORAL SPREAD | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NONLINEAR DOSE-RESPONSE | MEASLES-VIRUS | VESICULAR STOMATITIS-VIRUS | PHASE-I | MESENCHYMAL STEM-CELLS | T-CELLS | Neoplasms - therapy | Humans | Simplexvirus - genetics | Adenoviridae - genetics | Oncolytic Viruses - genetics | Clinical Trials as Topic | Genetic Vectors | Immunity, Cellular | Oncolytic Virotherapy | Biotechnology | Oncology | Viruses | Propagation | Cancer therapies
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2. Full Text Oncolytic Virotherapy
by Sze, Daniel Y., MD, PhD and Reid, Tony R., MD, PhD and Rose, Steven C., MD
Journal of Vascular and Interventional Radiology, ISSN 1051-0443, 2013, Volume 24, Issue 8, pp. 1115 - 1122
Abstract Oncolytic virotherapy is an emerging technology that uses engineered viruses to treat malignancies. Viruses can be designed with biological... 
Radiology | VIRUS NV1020 | JX-594 | I/II TRIAL | THERAPY | CLINICAL-TRIAL | PHASE-I TRIAL | INJECTION | PERIPHERAL VASCULAR DISEASE | REPLICATION-COMPETENT | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ADENOVIRUS ONYX-015 | Radiography, Interventional | History, 21st Century | History, 20th Century | Humans | Cytopathogenic Effect, Viral | Host Specificity | Oncolytic Viruses - genetics | Oncolytic Viruses - pathogenicity | Treatment Outcome | Neoplasms - history | Neoplasms - virology | Neoplasms - therapy | Animals | Oncolytic Virotherapy - history | Neoplasms - pathology | Oncolytic Virotherapy - adverse effects
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3. Full Text Oncolytic virotherapy
2012
Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons... 
Viruses | Treatment | Therapeutic use | Cancer
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4. Oncolytic virotherapy by HSV
by Watanabe, Daisuke and Goshima, Fumi
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2018, Volume 1045, pp. 63 - 84
Oncolytic virotherapy is a kind of antitumor therapy using viruses with natural or engineered tumor-selective replication to intentionally infect and kill... 
G207 | HSV1716 | Talimogene laherparepvec | OncoVEX | Oncolytic virotherapy | NV1020 | HSV | HF10 | Herpes simplex virus | T-VEC | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR | INTRATUMORAL INJECTION | REPLICATION-COMPETENT | PHASE I/II | CANCER | OncoVEX(GM-CSF) | HERPES-SIMPLEX-VIRUS | VIROLOGY | DNA-SEQUENCE | VIRAL THERAPY | BIOLOGY | TYPE-1 MUTANT HF10 | Oncolytic Virotherapy - methods | Neoplasms - therapy | Animals | Oncolytic Virotherapy - trends | Simplexvirus - physiology | Humans | Simplexvirus - genetics | Oncolytic Viruses - physiology | Oncolytic Viruses - genetics
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5. Full Text What is oncolytic virotherapy?
by Cockle, Julia V and Scott, Karen J
Archives of disease in childhood - Education & practice edition, ISSN 1743-0585, 02/2018, Volume 103, Issue 1, pp. 43 - 45
oncolytic virotherapy | PEDIATRICS | paediatric practice | IMMUNOTHERAPY | oncolytic virus | VIRUSES | Humans | Child, Preschool | Infant | Male | Oncolytic Viruses - pathogenicity | Neoplasms - virology | Oncolytic Virotherapy - methods | Neoplasms - therapy | Pediatrics - methods | Adolescent | Female | Child | Infant, Newborn
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6. Full Text Poxvirus oncolytic virotherapy
by Torres-Domínguez, Lino E and McFadden, Grant
Expert Opinion on Biological Therapy, ISSN 1471-2598, 06/2019, Volume 19, Issue 6, pp. 561 - 573
Introduction: Over the last decade, advances in biological therapies have resulted in remarkable clinical responses for the treatment of some previously... 
Vaccinia virus | Myxoma virus | oncolytic | virotherapy | oncolytic virus | MULTIPLE-MYELOMA | MEDICINE, RESEARCH & EXPERIMENTAL | SAFETY | IMMUNOTHERAPEUTIC VACCINIA VIRUS | IMMUNOCOMPETENT MOUSE MODEL | TUMOR-INITIATING CELLS | IN-VITRO | THERAPY | PEXA-VEC JX-594 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | XENOGRAFT MODEL
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7. Full Text Oncolytic polio virotherapy of cancer
by Brown, Michael C and Dobrikova, Elena Y and Dobrikov, Mikhail I and Walton, Ross W and Gemberling, Sarah L and Nair, Smita K and Desjardins, Annick and Sampson, John H and Friedman, Henry S and Friedman, Allan H and Tyler, Douglas S and Bigner, Darell D and Gromeier, Matthias
Cancer, ISSN 0008-543X, 11/2014, Volume 120, Issue 21, pp. 3277 - 3286
Recently, the century‐old idea of targeting cancer with viruses (oncolytic viruses) has come of age, and promise has been documented in early stage and several... 
innate antiviral response | eIF4G | oncolytic virus | nectin‐like molecule 5 | translation | interferon | internal ribosomal entry site | poliovirus | CD155 | nectin-like molecule 5 | VIRUS | CELL-MOVEMENT | FACTOR 4G1 EIF4G1 | TRANSLATION INITIATION | SIGNAL-TRANSDUCTION | MALIGNANT GLIOMA | HELICASE COMPLEX | MESSENGER-RNA | ONCOLOGY | RIBOSOME ENTRY SITE | BINDING | Neoplasms - virology | Neoplasms - therapy | Neoplasms - genetics | Humans | Immunotherapy | Immunity, Innate - genetics | Receptors, Virus - immunology | Oncolytic Viruses - genetics | Poliomyelitis - genetics | Oncolytic Virotherapy | Virus Internalization | IRES | Necl5
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8. Full Text Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy
by Ribas, Antoni and Dummer, Reinhard and Puzanov, Igor and VanderWalde, Ari and Andtbacka, Robert H.I and Michielin, Olivier and Olszanski, Anthony J and Malvehy, Josep and Cebon, Jonathan and Fernandez, Eugenio and Kirkwood, John M and Gajewski, Thomas F and Chen, Lisa and Gorski, Kevin S and Anderson, Abraham A and Diede, Scott J and Lassman, Michael E and Gansert, Jennifer and Hodi, F. Stephen and Long, Georgina V
Cell, ISSN 0092-8674, 09/2017, Volume 170, Issue 6, pp. 1109 - 1119.e10
Here we report a phase 1b clinical trial testing the impact of oncolytic virotherapy with talimogene laherparepvec on cytotoxic T cell infiltration and... 
T lymphocytes | pembrolizumab | interferon gamma | talimogene laherparepvec | biomarkers | tumor | oncolytic immunotherapy | melanoma | cytotixic | tumor microenvironment | oncolytic viruses | anti-PD-1 | PEMBROLIZUMAB | THERAPY | ADVANCED MELANOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADAPTIVE IMMUNE RESISTANCE | ANTIBODY | BLOCKADE | CANCER | TALIMOGENE LAHERPAREPVEC | IPILIMUMAB | CELL BIOLOGY | Antibodies, Monoclonal, Humanized - administration & dosage | Humans | Immunotherapy | Herpesviridae - genetics | Tumor Microenvironment | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Combined Modality Therapy | Melanoma - therapy | Oncolytic Virotherapy - adverse effects | Melanoma | Metastasis | Biological response modifiers | T cells | Gene expression | Health aspects | Interferon gamma
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9. Full Text Oncolytic virotherapy for malignant gliomas
by Forsyth, Peter A and Abate-Daga, Daniel
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 14, pp. 1440 - 1442
ONCOLOGY | IMMUNOTHERAPY | NEWLY-DIAGNOSED GLIOBLASTOMA | TUMOR STEM-CELLS | DELTA-24-RGD | DEATH | COMBINATION | ADENOVIRUS | CANCER | EXPRESSION | TEMOZOLOMIDE | Adenoviridae | Glioma | Oligopeptides | Humans | Immunotherapy | Neoplasm Recurrence, Local | Oncolytic Viruses | Oncolytic Virotherapy
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10. Full Text Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy
by Russell, Stephen J., MD, PhD and Federspiel, Mark J., PhD and Peng, Kah-Whye, PhD and Tong, Caili, MS and Dingli, David, MD, PhD and Morice, William G., MD, PhD and Lowe, Val, MD and O'Connor, Michael K., PhD and Kyle, Robert A., MD and Leung, Nelson, MD and Buadi, Francis K., MD and Rajkumar, S. Vincent, MD and Gertz, Morie A., MD and Lacy, Martha Q., MD and Dispenzieri, Angela, MD
Mayo Clinic Proceedings, ISSN 0025-6196, 2014, Volume 89, Issue 7, pp. 926 - 933
Abstract MV-NIS is an engineered measles virus that is selectively destructive to myeloma plasma cells and can be monitored by noninvasive radioiodine imaging... 
Internal Medicine | MULTIPLE-MYELOMA | ANTIBODIES | CELLS | IMMUNITY | MEDICINE, GENERAL & INTERNAL | CYCLOPHOSPHAMIDE | POXVIRUS | MEASLES-VIRUS | INDUCTION | CARRIERS | DELIVERY | Multiple Myeloma - diagnostic imaging | Oncolytic Virotherapy - methods | Multiple Myeloma - therapy | Humans | Middle Aged | Radionuclide Imaging | Female | Aged | Infusions, Intravenous | Oncolytic Viruses | Measles virus | Melanoma | Genetic aspects | Dosage and administration | Research | Gene expression | Drug therapy | Health aspects | Isotopes | Oncogenic viruses | Iodine
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11. Full Text Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy
by Bourgeois-Daigneault, Marie-Claude and Roy, Dominic Guy and Aitken, Amelia Sadie and El Sayes, Nader and Martin, Nikolas Tim and Varette, Oliver and Falls, Theresa and St-Germain, Lauren Elizabeth and Pelin, Adrian and Lichty, Brian Dennis and Stojdl, David Francis and Ungerechts, Guy and Diallo, Jean-Simon and Bell, John Cameron
Science Translational Medicine, ISSN 1946-6234, 01/2018, Volume 10, Issue 422, p. eaao1641
Triple-negative breast cancer (TNBC) is an aggressive disease for which treatment options are limited and associated with severe toxicities. Immunotherapeutic... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | JX-594 | VIRUS | IMMUNOTHERAPY | VEC | DISEASE | OUTCOMES | CARCINOMA | CELL BIOLOGY | Oncolytic Virotherapy - methods | Female | Humans | Neoadjuvant Therapy - methods | Triple Negative Breast Neoplasms - therapy | Oncolytic Viruses - physiology
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12. Full Text TGFβ treatment enhances glioblastoma virotherapy by inhibiting the innate immune response
by Han, Jianfeng and Chen, Xilin and Chu, Jianhong and Xu, Bo and Meisen, Walter H and Chen, Lichao and Zhang, Lingling and Zhang, Jianying and He, Xiaoming and Wang, Qi-En and Chiocca, E. Antonio and Kaur, Balveen and Caligiuri, Michael A and Yu, Jianhua
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 24, pp. 5273 - 5282
Oncolytic viruses, including oncolytic herpes simplex virus (oHSV), have produced provocative therapeutic responses in patients with glioblastoma, the most... 
GROWTH-FACTOR-BETA | NKG2D | ONCOLYTIC VIRUS THERAPY | NK CELLS | ONCOLOGY | INDUCTION | TUMORS | BRAIN | Immunity, Innate - drug effects | Humans | Reverse Transcriptase Polymerase Chain Reaction | Xenograft Model Antitumor Assays | Oncolytic Virotherapy - methods | Transforming Growth Factor beta - pharmacology | Simplexvirus | Animals | Brain Neoplasms - immunology | Flow Cytometry | Glioblastoma - immunology | Mice, Inbred NOD | Mice | Oncolytic Viruses | Immunosuppressive Agents - pharmacology | Real-Time Polymerase Chain Reaction | Disease Models, Animal | TGF-β | NK cells | glioblastoma | Oncolytic Herpes Simplex Virus | oncolytic viruses | innate immune response
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13. Full Text The advent of oncolytic virotherapy in oncology: The Rigvir® story
by Alberts, Pēteris and Tilgase, Andra and Rasa, Agnija and Bandere, Katrīna and Venskus, Dite
European Journal of Pharmacology, ISSN 0014-2999, 10/2018, Volume 837, pp. 117 - 126
Oncolytic viruses are a fast-developing cancer treatment field. Numerous viruses have been tested in clinical trials and three are approved. The first, Rigvir,... 
Rigvir | Oncolytic | ECHO-7 virus | Oncotropism | Melanoma | Virotherapy | NEWCASTLE-DISEASE-VIRUS | ECHOVIRUS INFECTION | ROSETTE FORMATION | FACTOR CD55 | CONTINUING SURVEILLANCE | CANCER-TREATMENT | HISTIOCYTIC SARCOMA | DECAY-ACCELERATING FACTOR | RHABDOMYOSARCOMA CELLS | PHARMACOLOGY & PHARMACY | Oncolytic Virotherapy - methods | Animals | Humans | Enterovirus B, Human | Clinical Trials as Topic | Drug Evaluation, Preclinical | Melanoma - therapy | Oncolytic Virotherapy - adverse effects | Immunologic Factors - therapeutic use | Melanoma - mortality | Oncology, Experimental | Mortality | Colorectal cancer | Development and progression | Metastasis | Research | Prevention | Analysis | Immunotherapy | Skin care products | Health aspects | Cancer
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14. Full Text Defining effective combinations of immune checkpoint blockade and oncolytic virotherapy
by Rojas, Juan J and Sampath, Padma and Hou, Weizhou and Thorne, Steve H
Clinical Cancer Research, ISSN 1078-0432, 12/2015, Volume 21, Issue 24, pp. 5543 - 5551
Purpose: Recent data from randomized clinical trials with oncolytic viral therapies and with cancer immunotherapies have finally recapitulated the promise... 
INTERFERON | THERAPY | PROTEIN | ONCOLOGY | SAFETY | POXVIRUS | TUMOR | ANTIBODY | VACCINIA VIRUS | CANCER-IMMUNOTHERAPY | CELL | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | Immunomodulation - drug effects | Immunotherapy - methods | Interleukin-2 Receptor alpha Subunit - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplasms - diagnosis | Molecular Targeted Therapy | Vaccinia virus - drug effects | Vaccinia virus - genetics | Neoplasms - therapy | Female | Antineoplastic Agents - pharmacology | Disease Models, Animal | Virus Replication - drug effects | Antibodies, Monoclonal - pharmacology | Oncolytic Viruses - genetics | Combined Modality Therapy | Genetic Vectors - genetics | Oncolytic Virotherapy - methods | Animals | B7-H1 Antigen - antagonists & inhibitors | Tumor Burden - drug effects | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | Cell Line, Tumor | Mice | CTLA-4 Antigen - antagonists & inhibitors | Immunity, Cellular | CTLA4 | Vaccinia | Oncolytic Virus | immunotherapy | checkpoint inhibitor
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15. Full Text Oncolytic Virotherapy: A Contest between Apples and Oranges
by Russell, Stephen J and Peng, Kah-Whye
Molecular Therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1107 - 1116
Viruses can be engineered or adapted for selective propagation in neoplastic tissues and further modified for therapeutic transgene expression to enhance their... 
competitive landscape | oncolytic virotherapy | viro-immuno-oncology | T-VEC | MEDICINE, RESEARCH & EXPERIMENTAL | CLINICAL-TRIAL | MEASLES VIRUSES | INTRAVENOUS DELIVERY | OVARIAN-CANCER | CANCER-THERAPY | HERPES-SIMPLEX-VIRUS | LAHERPAREPVEC T-VEC | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | VESICULAR STOMATITIS-VIRUS | TALIMOGENE LAHERPAREPVEC | ANTITUMOR EFFICACY | Lymph Nodes - pathology | Humans | Mutant Chimeric Proteins - genetics | Plasmacytoma - genetics | Multiple Myeloma - immunology | Plasmacytoma - immunology | Plasmacytoma - pathology | Measles virus - genetics | Multiple Myeloma - therapy | Antigen Presentation | Melanoma - genetics | Mutant Chimeric Proteins - metabolism | T-Lymphocytes - pathology | Skin Neoplasms - pathology | Antigens, Neoplasm - genetics | Oncolytic Virotherapy - trends | Genetic Vectors - chemistry | Herpesvirus 1, Human - metabolism | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Antigens, Neoplasm - immunology | Genetic Vectors - metabolism | Oncolytic Viruses - genetics | Lymph Nodes - immunology | Melanoma - pathology | Oncolytic Virotherapy - methods | Multiple Myeloma - pathology | Measles virus - metabolism | Melanoma - immunology | Oncolytic Viruses - immunology | Plasmacytoma - therapy | Skin Neoplasms - genetics | Herpesvirus 1, Human - genetics | T-Lymphocytes - immunology | Melanoma - therapy | Multiple Myeloma - genetics | Tumor cells | Immunomodulation | Melanoma | Antibodies | Viruses | Lymphocytes T | Kinases | Macrophages | Lymph nodes | Skin cancer | Metastases | Immune checkpoint | Immunotherapy | Antigen (tumor-associated) | Oncolysis | Review
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