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1. Full Text Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
by West, Nathaniel R and West, Nathaniel R and Hegazy, Ahmed N and Hegazy, Ahmed N and Owens, Benjamin M J and Owens, Benjamin M. J and Bullers, Samuel J and Bullers, Samuel J and Linggi, Bryan and Linggi, Bryan and Buonocore, Sofia and Buonocore, Sofia and Coccia, Margherita and Coccia, Margherita and Görtz, Dieter and Görtz, Dieter and This, Sébastien and This, Sébastien and Stockenhuber, Krista and Stockenhuber, Krista and Pott, Johanna and Pott, Johanna and Friedrich, Matthias and Friedrich, Matthias and Ryzhakov, Grigory and Ryzhakov, Grigory and Baribaud, Frédéric and Baribaud, Frédéric and Brodmerkel, Carrie and Brodmerkel, Carrie and Cieluch, Constanze and Cieluch, Constanze and Rahman, Nahid and Rahman, Nahid and Müller-Newen, Gerhard and Müller-Newen, Gerhard and Owens, Raymond J and Owens, Raymond J and Kühl, Anja A and Kühl, Anja A and Maloy, Kevin J and Maloy, Kevin J and Plevy, Scott E and Plevy, Scott E and Keshav, Satish and Travis, Simon P. L and Keshav, Satish and Powrie, Fiona and Travis, Simon P L and Powrie, Fiona and Bailey, Adam and Barnes, Ellie and Bird-Lieberman, Beth and Brain, Oliver and Braden, Barbara and Collier, Jane and East, James and Howarth, Lucy and Klenerman, Paul and Leedham, Simon and Palmer, Rebecca and Rodrigues, Astor and Simmons, Alison and Sullivan, Peter and Uhlig, Holm and Oxford IBD Cohort Investigators
Nature medicine, ISSN 1078-8956, 05/2017, Volume 23, Issue 5, pp. 579 - 589
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Immunohistochemistry | Colitis - genetics | Humans | Inflammatory Bowel Diseases - immunology | Middle Aged | Antibodies, Monoclonal - therapeutic use | Immunoblotting | Male | Gene Expression Profiling | Infliximab - therapeutic use | Inflammatory Bowel Diseases - metabolism | Case-Control Studies | Young Adult | Flow Cytometry | Inflammatory Bowel Diseases - genetics | Oncostatin M - metabolism | Adult | Female | Oncostatin M Receptor beta Subunit - metabolism | Oncostatin M Receptor beta Subunit - genetics | Colitis - immunology | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Inflammatory Bowel Diseases - drug therapy | Intercellular Adhesion Molecule-1 - immunology | Inflammation | Mice, Knockout | Animals | Gastrointestinal Agents - therapeutic use | Interleukin-6 - immunology | Aged | Mice | Oncostatin M Receptor beta Subunit - immunology | Oncostatin M - immunology | Chemokines | Oncostatin M - genetics | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Inflammatory bowel diseases | Usage | Cytokines | Tumor necrosis factor inhibitors | Physiological aspects | Drug therapy | Health aspects | Index Medicus
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2. Full Text Anti‐oncostatin M antibody inhibits the pro‐malignant effects of oncostatin M receptor overexpression in squamous cell carcinoma
by Kucia‐Tran, Justyna A and Tulkki, Valtteri and Scarpini, Cinzia G and Smith, Stephen and Wallberg, Maja and Paez‐Ribes, Marta and Araujo, Angela M and Botthoff, Jan and Feeney, Maria and Hughes, Katherine and Caffarel, Maria M and Coleman, Nicholas
The Journal of pathology, ISSN 0022-3417, 03/2018, Volume 244, Issue 3, pp. 283 - 295
cervix | oncostatin M receptor | metastasis | STAT3 | head and neck | neutralizing antibodies | squamous cell carcinoma | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Squamous Cell Carcinoma of Head and Neck - metabolism | Lung Neoplasms - drug therapy | Up-Regulation | Phosphorylation | Humans | Lung Neoplasms - metabolism | Squamous Cell Carcinoma of Head and Neck - pathology | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Uterine Cervical Neoplasms - pathology | Squamous Cell Carcinoma of Head and Neck - immunology | Head and Neck Neoplasms - metabolism | Uterine Cervical Neoplasms - metabolism | Squamous Cell Carcinoma of Head and Neck - drug therapy | Janus Kinase 2 - metabolism | Oncostatin M - metabolism | Female | Oncostatin M Receptor beta Subunit - metabolism | Oncostatin M Receptor beta Subunit - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Autocrine Communication | Oncostatin M Receptor beta Subunit - antagonists & inhibitors | Signal Transduction | Head and Neck Neoplasms - drug therapy | Janus Kinase 2 - genetics | Uterine Cervical Neoplasms - immunology | Uterine Cervical Neoplasms - drug therapy | Suppressor of Cytokine Signaling 3 Protein - genetics | Mice, SCID | Antineoplastic Agents, Immunological - pharmacology | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Head and Neck Neoplasms - immunology | Lung Neoplasms - immunology | Animals | Cell Line, Tumor | Mice, Inbred NOD | Oncostatin M Receptor beta Subunit - immunology | Suppressor of Cytokine Signaling 3 Protein - metabolism | Oncostatin M - genetics | Viral antibodies | Antibodies | Squamous cell carcinoma | Analysis | Copy number | Blocking antibodies | Stat3 protein | Activation | Metastasis | Cervix | Oncostatin M | Metastases | Angiogenesis | SOCS-3 protein | Autocrine signalling | Cervical carcinoma | Index Medicus
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3. Full Text Oncostatin M and interleukin-31: Cytokines, receptors, signal transduction and physiology
by Hermanns, Heike M
Cytokine & growth factor reviews, ISSN 1359-6101, 2015, Volume 26, Issue 5, pp. 545 - 558
Advanced Basic Science | Signal transduction | Inflammation | Interleukin-31 | Cytokines | Oncostatin M | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Janus Kinases - genetics | Humans | STAT Transcription Factors - immunology | Signal Transduction - genetics | Interleukins - genetics | Signal Transduction - immunology | STAT Transcription Factors - genetics | Animals | Interleukins - immunology | Janus Kinases - immunology | Mice | Oncostatin M Receptor beta Subunit - genetics | Oncostatin M Receptor beta Subunit - immunology | Oncostatin M - immunology | Oncostatin M - genetics | Physiological aspects | Cellular signal transduction | Interleukins | Analysis
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4. Full Text Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice
by Walker, Emma C and McGregor, Narelle E and Poulton, Ingrid J and Solano, Melissa and Pompolo, Sueli and Fernandes, Tania J and Constable, Matthew J and Nicholson, Geoff C and Zhang, Jian-Guo and Nicola, Nicos A and Gillespie, Matthew T and Martin, John and Sims, Natalie A
The Journal of clinical investigation, ISSN 0021-9738, 02/2010, Volume 120, Issue 2, pp. 582 - 592
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Osteocytes - drug effects | Luciferases - metabolism | Bone Development - drug effects | Signal Transduction | Bone Development - physiology | Osteoblasts - drug effects | RNA, Messenger - genetics | Organ Size | Glycoproteins | Oncostatin M - physiology | Oncostatin M - pharmacology | Receptors, OSM-LIF - physiology | Osteocytes - physiology | Bone and Bones - anatomy & histology | Animals | Receptors, Oncostatin M - physiology | Receptors, Oncostatin M - genetics | Genetic Markers - genetics | Bone Resorption - pathology | Oncostatin M - deficiency | Mice | Osteoblasts - cytology | Bone Morphogenetic Proteins - genetics | Oncostatin M - genetics | Bone resorption | Care and treatment | Growth | Leukemia | Development and progression | Bones | Cellular signal transduction | Properties | Observations | Statins | Index Medicus | Abridged Index Medicus
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5. Full Text Expression of short‐form oncostatin M receptor as a decoy receptor in lung adenocarcinomas
by Chen, DR and Chu, C‐Y and Chen, C‐Y and Yang, H‐C and Chiang, Y‐Y and Lin, T‐Y and Chiang, I‐P and Chuang, D‐Y and Yu, C‐C and Chow, K‐C
The Journal of pathology, ISSN 0022-3417, 07/2008, Volume 215, Issue 3, pp. 290 - 299
oncostatin M | oncostatin M receptor | interleukin‐6 | hepatocyte growth factor | lung adenocarcinoma | Oncostatin M receptor | Lung adenocarcinoma | Oncostatin M | Hepatocyte growth factor | Interleukin-6 | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Tumors of the respiratory system and mediastinum | Biological and medical sciences | Investigative techniques, diagnostic techniques (general aspects) | Medical sciences | Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques | Pneumology | Immunohistochemistry | Adenocarcinoma - pathology | Oncostatin M Receptor beta Subunit - analysis | Prognosis | Lung Neoplasms - mortality | Humans | Immunoblotting | Lung Neoplasms - pathology | Male | Cell Membrane - chemistry | RNA Interference | Oncostatin M - analysis | Oncostatin M - metabolism | Receptors, OSM-LIF - analysis | Female | Oncostatin M Receptor beta Subunit - metabolism | Oncostatin M Receptor beta Subunit - genetics | Adenocarcinoma - chemistry | Receptors, Oncostatin M - analysis | Gene Expression | Lung Neoplasms - chemistry | Receptors, Oncostatin M - metabolism | RNA, Small Interfering - pharmacology | Survival Rate | Cell Membrane - ultrastructure | Chi-Square Distribution | Reverse Transcriptase Polymerase Chain Reaction | Microscopy, Confocal | Receptors, Oncostatin M - genetics | Receptors, OSM-LIF - genetics | Oncostatin M - genetics | Adenocarcinoma - mortality | Index Medicus
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6. Full Text The AB loop of oncostatin M (OSM) determines species-specific signaling in humans and mice
by Adrian-Segarra, Juan M and Adrian-Segarra, Juan M and Sreenivasan, Krishnamoorthy and Sreenivasan, Krishnamoorthy and Gajawada, Praveen and Gajawada, Praveen and Lörchner, Holger and Lörchner, Holger and Braun, Thomas and Braun, Thomas and Pöling, Jochen and Pöling, Jochen
The Journal of biological chemistry, ISSN 0021-9258, 12/2018, Volume 293, Issue 52, pp. 20181 - 20199
cytokine | oncostatin M | signal transduction | cell signaling | STAT3 | OSM | LIFR | protein-protein interaction | OSMR | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Protein Structure, Secondary | Signal Transduction | Species Specificity | Humans | Leukemia Inhibitory Factor Receptor alpha Subunit - genetics | Animals | Leukemia Inhibitory Factor Receptor alpha Subunit - metabolism | Protein Multimerization - genetics | Oncostatin M - metabolism | Oncostatin M Receptor beta Subunit - metabolism | Mice | Oncostatin M Receptor beta Subunit - genetics | Oncostatin M - genetics | Index Medicus
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7. Full Text Remodeling and dedifferentiation of adult cardiomyocytes during disease and regeneration
by Szibor, Marten and Szibor, Marten and Pöling, Jochen and Pöling, Jochen and Warnecke, Henning and Warnecke, Henning and Kubin, Thomas and Kubin, Thomas and Braun, Thomas and Braun, Thomas
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 5/2014, Volume 71, Issue 10, pp. 1907 - 1916
Biochemistry, general | Myocardial infarction | Myoglobin | Dilative cardiomyopathy | Oncostatin M | Myocardial remodeling | Biomedicine general | Cell Biology | Life Sciences | Life Sciences, general | Hypoxia-inducible transcription factor | Hibernating myocardium | Hypertrophy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cardiomyopathy, Dilated - pathology | Myocytes, Cardiac - cytology | Receptors, Oncostatin M - metabolism | Heart - physiology | Humans | Cell Dedifferentiation | Cardiomyopathy, Dilated - metabolism | Regeneration | Receptors, Oncostatin M - antagonists & inhibitors | Ventricular Remodeling | Animals | Receptors, Oncostatin M - genetics | Myocytes, Cardiac - metabolism | Oncostatin M - metabolism | Heart failure | Physiological aspects | Analysis | Heart cells | Cardiomyocytes | Hypoxia | Cellular biology | Gene expression | Index Medicus
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8. Full Text Lack of oncostatin M receptor β leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype
by Komori, Tadasuke and Tanaka, Minoru and Senba, Emiko and Miyajima, Atsushi and Morikawa, Yoshihiro
The Journal of biological chemistry, ISSN 0021-9258, 07/2013, Volume 288, Issue 30, pp. 21861 - 21875
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Immunohistochemistry | Mannose-Binding Lectins - metabolism | Lipopolysaccharides - administration & dosage | Arginase - metabolism | Male | Oncostatin M - administration & dosage | Obesity - genetics | Adipose Tissue - metabolism | Lectins, C-Type - metabolism | Inflammation - metabolism | Interleukin-10 - metabolism | Oncostatin M - metabolism | Oncostatin M Receptor beta Subunit - metabolism | Oncostatin M Receptor beta Subunit - genetics | Cell Line | Macrophages - classification | Mice, Inbred C57BL | Adipose Tissue - pathology | Cells, Cultured | Insulin Resistance | Receptors, Cell Surface - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Obesity - metabolism | Microscopy, Confocal | Macrophages - metabolism | Phenotype | Animals | Interleukin-10 - genetics | Inflammation - genetics | Macrophages - drug effects | Mice | Adipose Tissue - drug effects | Oncostatin M - genetics | Index Medicus | Obesity | Cytokine | Inflammation | Metabolism | Adipose Tissue | Macrophages
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