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Organic Letters, ISSN 1523-7060, 09/2013, Volume 15, Issue 18, pp. 4826 - 4829
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2018, Volume 140, Issue 29, pp. 9020 - 9024
Native chemical ligation (NCL) combined with desulfurization chemistry has revolutionized the way in which large polypeptides and proteins are accessed by... 
PEPTIDE LIGATION | DESULFURIZATION CHEMISTRY | THERAPEUTICS | ONE-POT LIGATION | GLYCOPEPTIDE | VALINE | LIGHT | CYSTEINE | DESELENIZATION | PROTEIN-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Polymer Chemistry, ISSN 1759-9954, 11/2011, Volume 3, Issue 1, pp. 34 - 45
Branched polymers result in a more compact structure in comparison to linear polymers of identical molecular weight, due to their high segment density which... 
DRUG-LOADING CAPACITY | DIELS-ALDER | THIOL-ENE | POLYMER SCIENCE | LIVING RADICAL POLYMERIZATION | BLOCK-COPOLYMERS | ONE-POT SYNTHESIS | FRAGMENTATION CHAIN TRANSFER | ALDER CLICK REACTION | RING-OPENING POLYMERIZATION | MACROMOLECULAR ARCHITECTURES
Journal Article
Organic Letters, ISSN 1523-7060, 05/2012, Volume 14, Issue 10, pp. 2590 - 2593
Unsymmetrical bisazides containing chelating and nonchelating azido groups undergo chemoselective three-component copper(I)-catalyzed azide-alkyne conjugation... 
CHEMISTRY | CHEMISTRY, ORGANIC | MECHANISM | ONE-POT
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2016, Volume 138, Issue 14, pp. 4890 - 4899
Journal Article
Chemical Communications, ISSN 1359-7345, 03/2004, Volume 4, Issue 6, pp. 623 - 627
Journal Article
Chemical Science, ISSN 2041-6520, 02/2018, Volume 9, Issue 7, pp. 1982 - 1988
The ligation of sterically demanding peptidyl sites such as those involving Val-Val and Val-Pro linkages has proven to be extremely challenging with... 
KINETICALLY CONTROLLED LIGATION | ONE-POT LIGATION | CHEMISTRY | MEMBRANE-PROTEIN | CYSTEINE | THIOESTER PRECURSORS | DESULFURIZATION | SELENOCYSTEINE | PROTEIN-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | LINKER
Journal Article
Chemical Science, ISSN 2041-6520, 01/2018, Volume 9, Issue 7, pp. 1982 - 1988
The ligation of sterically demanding peptidyl sites such as those involving Val–Val and Val–Pro linkages has proven to be extremely challenging with... 
Peptides | Additives | Thioesters
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 10/2018, Volume 83, Issue 20, pp. 12584 - 12594
N-Alkyl bis­(2-selanylethyl)­amines catalyze the synthesis of peptide thioesters or peptide ligation from bis­(2-sulfanylethyl)­amido (SEA) peptides. These... 
ONE-POT LIGATION | HYDRAZIDES | SURROGATES | NATIVE CHEMICAL LIGATION | SELENOESTERS | REACTIVITY | CHEMISTRY, ORGANIC | CYSTEINE | DESULFURIZATION | SELENOCYSTEINE | PROTEINS | Analytical chemistry | Organic chemistry | Chemical Sciences
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 11/2017, Volume 53, Issue 90, pp. 12236 - 12239
1,2,4-Triazole facilitated native chemical ligation (NCL) between peptide-MeNbz (MeNbz: N-acyl-N'-methyl-benzimidazolinone) and a cysteinyl peptide in the... 
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 11/2017, Volume 53, Issue 90, pp. 12236 - 12239
1,2,4-Triazole facilitated native chemical ligation (NCL) between peptide-MeNbz (MeNbz: N-acyl-N'-methyl-benzimidazolinone) and a cysteinyl peptide in the... 
ACTIVATION | BRAIN NATRIURETIC PEPTIDE | ONE-POT LIGATION | THIOL | HYDROLYSIS | CHEMISTRY | DESULFURIZATION | 1-ACYL-1,2,4-TRIAZOLES | PROTEIN-SYNTHESIS | PRECURSORS | CHEMISTRY, MULTIDISCIPLINARY | Additives | Oxidation | Peptides | Iodine
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 11/2018, Volume 24, Issue 66, p. n/a
A side‐chain unprotected peptide with C‐terminal thioesters can chemoselectively react with another side‐chain unprotected peptide carrying an N‐terminal... 
native chemical ligation (NCL) | desulfurization | cysteine surrogates | one-pot synthesis | proteins | Proteins | Protein biosynthesis | Cysteine | Desulfurization | Alanine | Thioesters | Peptides | Amino acids | Chains | Organic chemistry | Protein synthesis | Chemical synthesis | Desulfurizing
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2018, Volume 59, Issue 3, pp. 268 - 271
Protein chemical synthesis can provide the homogeneous atypical ubiquitin chains that are usually difficult to obtain by other methods. Herein, we report a new... 
Isopeptide-linked Ub (isoUb) | Atypical ubiquitin chains | Trifluoroacetamidomethyl group | One-pot native chemical ligation | SYSTEM | METHYLATION | SPECIFICITY | CHEMISTRY, ORGANIC | PEPTIDE HYDRAZIDES | DEUBIQUITINASE CEZANNE | LINKAGES | UBIQUITYLATION | DEGRADATION | PROTEIN CHEMICAL-SYNTHESIS | Ubiquitin | Chemical synthesis
Journal Article
CHEMICAL REVIEWS, ISSN 0009-2665, 06/2019, Volume 119, Issue 12, pp. 7328 - 7443
Journal Article
Organic Letters, ISSN 1523-7060, 2019, Volume 21, Issue 13, pp. 5138 - 5142
Here, we describe an Se-auxiliary mediated ligation protocol capable of rapid native chemical ligations at sterically hindered junctions, followed by in situ... 
PEPTIDE LIGATION | ONE-POT LIGATION | DNA-SEQUENCE | NATIVE CHEMICAL LIGATION | PHOTOCLEAVABLE AUXILIARY | CHEMISTRY, ORGANIC | CYSTEINE | DESULFURIZATION | DESELENIZATION | SELENOCYSTEINE | POLYPEPTIDES
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2018, Volume 57, Issue 8, pp. 2170 - 2173
Chemical conjugation between hydrophilic and hydrophobic components is difficult because of their extremely different solubility. Herein, we report a new... 
peptide–drug conjugate | solubility | solid-phase synthesis | synthetic methods | MEMBRANE | STRATEGY | peptide-drug conjugate | ANTIBODY | PLINABULIN | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDES | CHEMISTRY | ARGININE | PROTEINS | ANTICANCER DRUG-DELIVERY | Chemical synthesis | Methods | Solvents | Conjugation | Hydrophobicity | Substrates | Solubility
Journal Article
Chemistry – An Asian Journal, ISSN 1861-4728, 10/2019, Volume 14, Issue 19, pp. 3251 - 3254
Circular single‐stranded DNA (c‐ssDNA) has significant applications in DNA detection, the development of nucleic acid medicine, and DNA nanotechnology because... 
DNA nanotechnology | Circular single-stranded DNA | Biosynthesis | Ligases | One-pot reaction
Journal Article
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