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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 02/2017, Volume 58, Issue 2
PURPOSE. Dominant optic atrophy (MIM No. 165500) is a blinding condition related to mutations in OPA1, a gene encoding a large GTPase involved in mitochondrial... 
APOPTOSIS | mitochondria | optic neuropathy | NEURODEGENERATION | CARNOSINE | SPERMIDINE | DEFICIENCY | MITOCHONDRIAL MORPHOLOGY | OPA1 | metabolomics | MOUSE MODEL | EARLY-ONSET | OPHTHALMOLOGY | dominant optic atrophy | DYNAMIN-RELATED PROTEIN | OPA1 MUTATIONS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 45, pp. 16017 - 16022
Journal Article
Klinische Monatsblatter fur Augenheilkunde, ISSN 0023-2165, 2018, Volume 235, Issue 11, pp. 1235 - 1241
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2017, Volume 36, Issue 14, pp. 2126 - 2145
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12886 - 12886
Mitochondria form interconnected networks that dynamically remodel in response to cellular needs. Using live-cell imaging, we investigate the role of the actin... 
ORGANIZATION | MITOSIS | OUTER-MEMBRANE | F-ACTIN | OPA1 | DNA | MULTIDISCIPLINARY SCIENCES | NEURONS | DIVISION | DRP1
Journal Article
Revue Neurologique, ISSN 0035-3787, 04/2014, Volume 170, pp. A15 - A15
Journal Article
SCIENCE, ISSN 0036-8075, 01/2016, Volume 351, Issue 6270, pp. 275 - 281
Mitochondria undergo fragmentation in response to electron transport chain (ETC) poisons and mitochondrial DNA-linked disease mutations, yet how these stimuli... 
PROTEOLYTIC CLEAVAGE | APOPTOSIS | FUSION | OPA1 | STRUCTURAL BASIS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | AUTOPHAGY | MAMMALIAN-CELLS | DRP1 | Energy metabolism | Bioenergetics | Physiological aspects | Mitochondrial DNA | Genetic aspects | Adenylic acid | Protein kinases | Mitochondria | Cellular biology | Metabolism | Cytoplasm
Journal Article
Journal of the Neurological Sciences, ISSN 0022-510X, 2015, Volume 349, Issue 1, pp. 154 - 160
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 01/2017, Volume 58, Issue 1, pp. 502 - 516
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2019, Volume 294, Issue 34, pp. jbc.RA119.007601 - 12598
Patients with fatty liver diseases present altered mitochondrial morphology and impaired metabolic function. Mitochondrial dynamics and related cell function... 
Index Medicus | Editors' Picks | hepatocyte | OPA1 | liver | mitochondria | liver metabolism | gluconeogenesis | mitochondrial metabolism | prohibitins
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 10/2015, Volume 1847, Issue 10, pp. 1075 - 1084
It was recently suggested that electron flow into cyt , coupled with ROS generation, oxidizes cyt Met to Met sulfoxide (Met-O) in isolated hearts after... 
Mitochondria cristae | SS-20 | OPA1 | Electron transport | Methionine sulfoxide | cyt c oxygenase | PROTEOLYTIC CLEAVAGE | OXIDATIVE-PHOSPHORYLATION | CARDIOLIPIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPERFUSION INJURY | HORSE HEART | ELECTRON-TRANSPORT CHAIN | OXYGEN | PEROXIDASE-ACTIVITY | PROTEIN OPA1 | BIOPHYSICS | KIDNEY INJURY | Cytochrome c | Ischemia | Heme
Journal Article
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 05/2017, Volume 12, Issue 1, pp. 1 - 10
Journal Article