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1. Full Text Effect of Chronic Delivery of the Toll-like Receptor 4 Antagonist ( + )-Naltrexone on Incubation of Heroin Craving
by Theberge, Florence R and Li, Xuan and Kambhampati, Sarita and Pickens, Charles L and St. Laurent, Robyn and Bossert, Jennifer M and Baumann, Michael H and Hutchinson, Mark R and Rice, Kenner C and Watkins, Linda R and Shaham, Yavin
Biological psychiatry (1969), ISSN 0006-3223, 2013, Volume 73, Issue 8, pp. 729 - 737
Psychiatry | extinction | reinstatement | relapse | Craving | opioid drugs | glia | heroin self-administration | TLR4 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Drug addictions | Drug addiction | Toxicology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Addictive behaviors | Biological and medical sciences | Medical sciences | Behavior, Addictive - drug therapy | Cues | Naltrexone - therapeutic use | Drug Administration Schedule | Stereoisomerism | Extinction, Psychological - drug effects | Rats | Dose-Response Relationship, Drug | Naltrexone - pharmacology | Self Administration | Animals | Conditioning, Operant - drug effects | Narcotic Antagonists - therapeutic use | Time Factors | Methamphetamine - administration & dosage | Narcotic Antagonists - pharmacology | Heroin - administration & dosage | Toll-Like Receptor 4 - antagonists & inhibitors | Infusion Pumps, Implantable - psychology | Naltrexone - administration & dosage | Physiological aspects | Naltrexone | Heroin | Index Medicus | craving
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2. Full Text Angiotensin II receptor type 1 (AT 1) selective nonpeptidic antagonists—A perspective
by Naik, Prashant and Murumkar, Prashant and Giridhar, Rajani and Yadav, Mange Ram
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 24, pp. 8418 - 8456
Antihypertensive | Renin angiotensin system | Angiotensin receptor blocker | Molecular modeling | AT1 receptor | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Cardiovascular system | Neurotransmitters. Neurotransmission. Receptors | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Neuropharmacology | Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems | Antihypertensive agents | Antihypertensive Agents - chemistry | Losartan - chemistry | Angiotensin II Type 1 Receptor Blockers - chemistry | Angiotensin Receptor Antagonists - chemistry | Humans | Index Medicus
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3. Full Text Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
by Manglik, Aashish and Kruse, Andrew C and Kobilka, Tong Sun and Thian, Foon Sun and Mathiesen, Jesper M and Sunahara, Roger K and Pardo, Leonardo and Weis, William I and Kobilka, Brian K and Granier, Sébastien
Nature (London), ISSN 0028-0836, 05/2012, Volume 485, Issue 7398, pp. 321 - 326
Structure of solids and liquids; crystallography | Structure of specific crystalline solids | Physics | Exact sciences and technology | Condensed matter: structure, mechanical and thermal properties | Organic compounds | Morphinans - chemistry | Receptors, Opioid, mu - chemistry | Receptors, Opioid, mu - metabolism | Solvents - chemistry | Protein Multimerization | Models, Molecular | Crystallography, X-Ray | Receptors, Opioid, mu - antagonists & inhibitors | Animals | Morphinans - metabolism | Ligands | Protein Conformation | Mice | Binding Sites | Morphinans - pharmacology | Proteins | Crystal structure | Index Medicus
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4. Full Text In vivo effects of μ‐opioid receptor agonist/δ‐opioid receptor antagonist peptidomimetics following acute and repeated administration
by Anand, Jessica P and Kochan, Kelsey E and Nastase, Anthony F and Montgomery, Deanna and Griggs, Nicholas W and Traynor, John R and Mosberg, Henry I and Jutkiewicz, Emily M
British journal of pharmacology, ISSN 0007-1188, 06/2018, Volume 175, Issue 11, pp. 2013 - 2027
Peptidomimetics - pharmacology | Cricetulus | Humans | Mice, Inbred C57BL | Molecular Conformation | Analgesics, Opioid - pharmacology | Rats | Male | Peptidomimetics - chemistry | Receptors, Opioid, mu - agonists | Mice, Knockout | Peptidomimetics - administration & dosage | Animals | Analgesics, Opioid - administration & dosage | Analgesics, Opioid - chemistry | Cell Line, Tumor | Female | Ligands | Receptors, Opioid, delta - antagonists & inhibitors | Mice | CHO Cells | Pain perception | Opioid receptors | Narcotics | Morphine | Naltrexone | Side effects | Receptors | Pain | Analgesics | Drug tolerance | Peptidomimetics | Dependence | Warm water | In vivo methods and tests | Conditioning | Research Papers | Research Paper
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5. Full Text Development of κ Opioid Receptor Antagonists
by Carroll, F. Ivy and Carlezon, William A
Journal of medicinal chemistry, ISSN 0022-2623, 03/2013, Volume 56, Issue 6, pp. 2178 - 2195
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Amino Acid Sequence | Receptors, Opioid, kappa - antagonists & inhibitors | Animals | Peptides - chemistry | Humans | Molecular Sequence Data | Drug Discovery - methods | Clinical Trials as Topic | Peptides - pharmacology | Index Medicus
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6. Full Text AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: Implications for opioid/cannabinoid interaction studies
by Seely, Kathryn A and Brents, Lisa K and Franks, Lirit N and Rajasekaran, Maheswari and Zimmerman, Sarah M and Fantegrossi, William E and Prather, Paul L
Neuropharmacology, ISSN 0028-3908, 10/2012, Volume 63, Issue 5, pp. 905 - 915
Analgesia | Morphine | Marijuana | G-protein | Adenylyl cyclase | CB1 receptors | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Pyrazoles - therapeutic use | Receptor, Cannabinoid, CB2 - agonists | Humans | Analgesics, Opioid - pharmacology | Receptors, Opioid, mu - agonists | Piperidines - pharmacology | Cannabinoid Receptor Agonists - therapeutic use | Recombinant Proteins - antagonists & inhibitors | Piperidines - metabolism | Receptors, Opioid, mu - metabolism | Morpholines - metabolism | Analgesics, Non-Narcotic - metabolism | Drug Inverse Agonism | Mice | Analgesics, Opioid - metabolism | Kinetics | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Analgesics, Opioid - antagonists & inhibitors | Cannabinoid Receptor Agonists - metabolism | Cricetulus | Analgesics, Non-Narcotic - pharmacology | Cannabinoid Receptor Agonists - pharmacology | Receptor, Cannabinoid, CB2 - genetics | Analgesics, Opioid - adverse effects | Narcotic Antagonists - metabolism | Receptor, Cannabinoid, CB1 - agonists | Analgesics, Non-Narcotic - adverse effects | Cannabinoid Receptor Agonists - adverse effects | Morpholines - adverse effects | CHO Cells | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Binding, Competitive | Recombinant Proteins - metabolism | Cricetinae | Morpholines - pharmacology | Narcotic Antagonists - adverse effects | Recombinant Proteins - agonists | Analgesics, Non-Narcotic - therapeutic use | Pyrazoles - metabolism | Mice, Inbred Strains | Receptors, Opioid, mu - antagonists & inhibitors | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Narcotic Antagonists - therapeutic use | Piperidines - therapeutic use | Narcotic Antagonists - pharmacology | Piperidines - adverse effects | Receptors, Opioid, mu - genetics | Index Medicus | Drugs | Pain perception | Opioid receptors | Cyclic AMP | Opioid receptors (type mu) | Antagonists | Cannabinoid CB1 receptors | Guanine nucleotide-binding protein | Antagonism | Cell activation | Side effects | Inverse agonists | CB1 Receptors | Adenylyl Cyclase
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