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Journal of the American Chemical Society, ISSN 0002-7863, 12/2019, Volume 141, Issue 51, pp. 20048 - 20052
An enantioselective total synthesis of (-)-oridonin is accomplished based on a key interrupted Nazarov reaction. The stereochemistry of the... 
REARRANGEMENT | ORIDONIN | CONVERSION | ANALOGS | DITERPENOIDS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2020, Volume 187, p. 111978
Hydrogen sulfide (H S) has been recognized as the third endogenous signaling gasotransmitter following nitric oxide (NO) and carbon monoxide (CO), and exhibits... 
Hydrogen sulfide | ent-kaurane | Antiproliferative activity | Oridonin | Apoptosis
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 03/2017, Volume 37, Issue 3, pp. 759 - 766
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2014, Volume 15, Issue 15, pp. 6437 - 6441
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 01/2020, Volume 9
Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its... 
oridonin | RNA seq | p53-mutation | esophageal squamous cell carcinoma cells | glutathione
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 07/2017, Volume 37, Issue 7, pp. 1701 - 1713
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2018, Volume 33, Issue 1, pp. 324 - 333
To identify anticancer agents with higher potency and lower toxicity, a series of oridonin derivatives with substituted benzene moieties at the C17 position... 
synthesis | apoptosis | anticancer | Oridonin | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGICAL EVALUATION | NATURAL ORIDONIN | DERIVATIVES | ANTITUMOR | CANCER | DITERPENOID ANALOGS | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 05/2018, Volume 826, pp. 133 - 139
Oridonin, an active diterpenoid compound isolated from the plant Rabdosia Rrubescens, has various pharmacological activities, including antioxidant, anti-tumor... 
Endothelial cells | Oridonin | Vascular inflammation | ADHESION | PROTEIN-1 | PATHWAY | ENDOTHELIAL-CELLS | DISEASE | ATHEROSCLEROSIS | PHARMACOLOGY & PHARMACY | DYSFUNCTION | EXPRESSION
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 12/2017, Volume 17, Issue 12, pp. 1679 - 1688
Background: Recently, we devoted to disclosing the antibacterial activities of enmein-type 6,7-seco-ent-kauranoid derivatives. Objective: Eleven new... 
Antimicrobial | Antiproliferative | Enmein-type | Diterpenoid | Derivatives | SAR | antimicrobial | SPIROLACTONE-TYPE | ANTIMYCOBACTERIAL | DESIGN | CHEMISTRY, MEDICINAL | ANALOGS | ANTICANCER AGENTS | ANTIBACTERIAL | NATURAL ORIDONIN | ANTITUMOR AGENTS | derivatives | ONCOLOGY | KAURENE-TYPE ORIDONIN | enmein-type | BIOLOGICAL EVALUATION | diterpenoid
Journal Article
National Medical Journal of China, ISSN 0376-2491, 12/2017, Volume 97, Issue 46, pp. 3647 - 3651
Journal Article