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genetic predisposition to disease (58) 58
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17q21 (19) 19
asthma - immunology (18) 18
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research (18) 18
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genetic research (17) 17
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activation (16) 16
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single-nucleotide polymorphism (15) 15
polymorphisms (13) 13
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single nucleotide polymorphisms (13) 13
asthma - drug therapy (12) 12
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chromosome 17q21 (12) 12
chromosomes, human, pair 17 (12) 12
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Nature Reviews Genetics, ISSN 1471-0056, 03/2009, Volume 10, Issue 3, pp. 184 - 194
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 4, pp. 1035 - 1046.e6
Journal Article
Experimental Cell Research, ISSN 0014-4827, 09/2018, Volume 370, Issue 2, pp. 498 - 505
Orosomucoid 1-like protein 3 (ORMDL3) is an asthma candidate gene associated with virus-triggered recurrent wheeze. Stimulator of interferon gene (STING)... 
Recurrent wheeze | Orosomucoid 1-like protein 3 (ORMDL3) | Stimulator of interferon genes (STING) | TBK1-STAT6-IRF3 complex | ACTIVATION | VIRUS | KERATINOCYTES | MECHANISMS | CELL BIOLOGY | INTERFERON | GENE | ONCOLOGY | ADAPTER | ASTHMA | STAT6 | INNATE IMMUNE SENSOR | Genes | Genetic research | Albumin | Interferon | Biological response modifiers | Gene expression | Mediation
Journal Article
Experimental Cell Research, ISSN 0014-4827, 11/2018, Volume 372, Issue 1, pp. 43 - 51
Orosomucoid like-3 (ORMDL3) has been identified to be associated with the development of asthma according to previous studies. However, the definite role of... 
ORMDL3 | DNA methylation | 5-Aza-CdR-2'-deoxycytidine | IL-6, IL-8 | MMP-9 | p-ERK | Childhood asthma | KINASE | RISK | MECHANISMS | IL-8 | IL-6 | CELL BIOLOGY | 5-Aza-CdR-2 '-deoxycytidine | AIRWAY | ONCOLOGY | Cytokines | Methylation | Asthma in children
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2018, Volume 142, Issue 2, pp. 706 - 709.e4
ZPBP2 is highly expressed in sperm, where it is known to be required for formation of mature spermatozoa.9 During fertilization, ZPBP2 binds to the zona... 
SEVERE DERMATITIS | GSDMB | MULTIPLE ALLERGIES | AIRWAY RESPONSIVENESS | ALLERGY | RECESSIVE DSG1 MUTATIONS | ORMDL3 | DOMINANT | PLAKIN DOMAIN | SAM SYNDROME | IMMUNOLOGY | DESMOPLAKIN | Laboratories | Sperm | Pathogenesis | Smooth muscle | Inflammation | Zona pellucida | Asthma | Proteins | Studies | Lungs | Lymphocytes | Rodents | Fibroblasts | Bone marrow | Chromosomes | Chromosome 17
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 4, pp. 860 - 863
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0172707
Chromosomal region 17q12-q21 is associated with asthma and harbors regulatory polymorphisms that influence expression levels of all five protein-coding genes... 
GENOME-WIDE LINKAGE | CHROMATIN | 17Q21 | MULTIDISCIPLINARY SCIENCES | ORMDL3 | GENE-EXPRESSION | CTCF-BINDING | RISK | ASSOCIATION | LOCUS | CHILDHOOD ASTHMA | Cell Line | Promoter Regions, Genetic | Up-Regulation | Genetic Predisposition to Disease | Genome-Wide Association Study | Epithelial Cells - metabolism | Membrane Proteins - genetics | Humans | Gene Expression Regulation | Azacitidine - chemistry | Genotype | Gene Expression Profiling | Amino Acid Motifs | Ikaros Transcription Factor - genetics | DNA Methylation | Phenotype | MCF-7 Cells | Alleles | HEK293 Cells | Polymorphism, Single Nucleotide | Neoplasm Proteins - genetics | Binding Sites | Egg Proteins - genetics | Promoters (Genetics) | Epithelial cells | DNA | Genetic aspects | Research | Gene expression | Methylation | Asthma | Adenocarcinoma | Haplotypes | Azacytidine | Ikaros protein | Laboratories | Genes | Genomics | Genomes | Biosynthesis | Single-nucleotide polymorphism | Respiratory tract | Proteins | Demethylation | DNA methylation | Genetics | Physiology | Zinc finger proteins | Chromosome 17 | Deoxyribonucleic acid--DNA | Gynecology | Epithelium | Ribonucleic acid--RNA | Obstetrics | Zona pellucida | Zinc | Lungs | Cell lines | Epigenetics | DNA methyltransferase | Binding sites | Kidney transplantation | RNA | Deoxyribonucleic acid | Ribonucleic acid
Journal Article
Journal Article
PLoS genetics, ISSN 1553-7404, 11/2012, Volume 8, Issue 11, p. e1003029
Journal Article