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apelin (151) 151
orphan receptor apj (124) 124
humans (114) 114
animals (105) 105
index medicus (99) 99
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apelin receptors (56) 56
blood-pressure (56) 56
peptide apelin (49) 49
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in-vivo (48) 48
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intercellular signaling peptides and proteins (47) 47
orphan receptor (45) 45
apj (44) 44
cardiac contractility (44) 44
pharmacology & pharmacy (42) 42
endothelial-cells (41) 41
cardiac & cardiovascular systems (39) 39
mice (38) 38
receptors, g-protein-coupled - metabolism (38) 38
heart-failure (36) 36
middle aged (36) 36
endogenous peptide ligand (35) 35
tissue distribution (35) 35
endogenous ligand apelin (34) 34
heart failure (34) 34
biochemistry & molecular biology (33) 33
intercellular signaling peptides and proteins - blood (33) 33
ligand (33) 33
messenger-rna (33) 33
endogenous ligand (32) 32
ligands (32) 32
physiology (32) 32
intercellular signaling peptides and proteins - metabolism (31) 31
endocrinology & metabolism (28) 28
adipokines (27) 27
adult (27) 27
peptides (27) 27
apj receptor (24) 24
carrier proteins - metabolism (24) 24
aged (23) 23
expression (23) 23
nitric-oxide (23) 23
peripheral vascular disease (23) 23
receptors, g-protein-coupled - genetics (22) 22
signal transduction (20) 20
immunocytochemical localization (19) 19
biomarkers - blood (18) 18
immunodeficiency-virus type-1 (18) 18
intercellular signaling peptides and proteins - pharmacology (18) 18
food-intake (17) 17
obesity (17) 17
vascular smooth-muscle (17) 17
article (16) 16
brain (16) 16
carrier proteins - genetics (16) 16
cell biology (16) 16
contractility (16) 16
endogenous inotrope apelin (16) 16
physiological aspects (16) 16
heart (15) 15
hypertension (15) 15
intercellular signaling peptides and proteins - physiology (15) 15
myocardium - metabolism (15) 15
protein-coupled receptor (15) 15
carrier proteins - pharmacology (14) 14
carrier proteins - physiology (14) 14
medicine, research & experimental (14) 14
phosphorylation (14) 14
receptors, g-protein-coupled - physiology (14) 14
analysis (13) 13
intercellular signaling peptides and proteins - genetics (13) 13
peptide (13) 13
plasma apelin (13) 13
rats, wistar (13) 13
amino acid sequence (12) 12
cardiovascular (12) 12
cardiovascular system (12) 12
cells, cultured (12) 12
heart failure - physiopathology (12) 12
human apj receptor (12) 12
insulin (12) 12
molecular sequence data (12) 12
proteins (12) 12
angiotensin (11) 11
angiotensin-ii (11) 11
natural ligand (11) 11
orphan 7-transmembrane receptor (11) 11
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research (11) 11
rodents (11) 11
apelin receptor (10) 10
blood pressure - drug effects (10) 10
cardiovascular disease (10) 10
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diabetes (10) 10
g-protein (10) 10
hematology (10) 10
immunohistochemistry (10) 10
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Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 03/2003, Volume 84, Issue 5, pp. 1162 - 1172
Journal Article
Peptides, ISSN 0196-9781, 01/2019, Volume 111, pp. 62 - 70
Apelin is an endogenous peptide ligand for the G protein-coupled receptor APJ/AGTRL1/APLNR and is widely expressed throughout human body. In adult hearts... 
Beta-arreatin | Apela | Angiotensin converting enzyme 2 (ACE2) | Aplnr | APJ | Toddler | Elabela | Angiotensin II | Apelin | G protein | II TYPE-1 RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOGENOUS PEPTIDE LIGAND | ORPHAN RECEPTOR | PROTECTS | APJ RECEPTOR | RENIN-ANGIOTENSIN SYSTEM | PLASMA APELIN | PATHWAY | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY | MYOCARDIAL INJURY
Journal Article
HEART, ISSN 1355-6037, 07/2010, Volume 96, Issue 13, pp. 1011 - 1016
Apelin, the endogenous ligand for the G-protein-coupled APJ receptor, is emerging as a key hormone in cardiovascular homoeostasis. It is expressed in a diverse... 
HEART | CARDIAC & CARDIOVASCULAR SYSTEMS | CONTRACTILITY | PLASMA APELIN | PEPTIDE LIGAND | IN-VIVO | NITRIC-OXIDE | ORPHAN RECEPTOR APJ | ANGIOTENSIN-II | ENDOGENOUS INOTROPE APELIN | BLOOD-PRESSURE
Journal Article
Life Sciences, ISSN 0024-3205, 09/2019, Volume 232, p. 116645
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications. Apelin (APLN) is a key molecule, whose roles during CVD have... 
Inflammation | Cardiovascular diseases | Atherosclerosis | Apelin | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | ACTIVATION | APELIN RECEPTOR | LIPOPROTEIN-LIPASE | ANGIOTENSIN RECEPTOR | PHARMACOLOGY & PHARMACY | ORPHAN RECEPTOR APJ | LIGAND | NEOVASCULARIZATION | EXPRESSION | Macrophages | Complications
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 05/2008, Volume 75, Issue 10, pp. 1882 - 1892
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2011, Volume 31, Issue 4, pp. 814 - 820
OBJECTIVE—The G-protein–coupled receptor APJ and its ligand apelin are highly expressed in the pulmonary vasculature, but their function in this vascular bed... 
endothelial function | nitric oxide synthase | apelin | pulmonary hypertension | AMP-activated kinase | ENDOGENOUS LIGAND APELIN | ACTIVATED PROTEIN-KINASE | NITRIC-OXIDE SYNTHASE | MESSENGER-RNA | ENDOTHELIAL-CELLS | ARTERIAL-HYPERTENSION | IN-VIVO | PERIPHERAL VASCULAR DISEASE | ORPHAN RECEPTOR APJ | KRUPPEL-LIKE FACTOR-2 | GENE-TRANSFER | HEMATOLOGY | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Receptors, G-Protein-Coupled - metabolism | Humans | Middle Aged | Hypertension, Pulmonary - diagnostic imaging | Hypertension, Pulmonary - physiopathology | Male | Mice, 129 Strain | Pulmonary Artery - diagnostic imaging | X-Ray Microtomography | Case-Control Studies | Hypoxia - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Pulmonary Artery - metabolism | Kruppel-Like Transcription Factors - metabolism | Adult | Female | Nitric Oxide Synthase Type III - metabolism | Apelin | Disease Models, Animal | Severity of Illness Index | Receptors, G-Protein-Coupled - blood | Signal Transduction | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Hypertension, Pulmonary - genetics | Hypertension, Pulmonary - metabolism | Hypoxia - complications | Pulmonary Artery - physiopathology | Adipokines | Mice, Knockout | Carrier Proteins - genetics | Hypoxia - genetics | Animals | Carrier Proteins - metabolism | Apelin Receptors | Mice | Nitric Oxide - metabolism | Hypertension, Pulmonary - etiology
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