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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 4, pp. 1038 - 1043
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
by Zhang, Q and Qiao, W and Zhou, L and Jin, H and Zheng, KL and Zhao, DS and Lu, HH
ANNALS OF TRANSLATIONAL MEDICINE, ISSN 2305-5839, 10/2018, Volume 6, Issue 20, pp. 408 - 408
Background: An osteoclast-associated receptor (OSCAR) is an immunoglobulin receptor expressed in an ostcoclast, and takes part in the formation of an... 
MEDICINE, RESEARCH & EXPERIMENTAL | osteoclast-associated receptor | acute coronary syndrome | ONCOLOGY | Immunoglobulin receptor | LOW-DENSITY-LIPOPROTEIN | EXPRESSION | SEVERITY | OSCAR | Original
Journal Article
European Journal of Immunology, ISSN 0014-2980, 04/2016, Volume 46, Issue 4, pp. 952 - 963
Osteoclast‐associated receptor (OSCAR) is an activating receptor expressed by human myeloid cells. Collagen type I (ColI) and collagen type II (ColII) serve as... 
Autoimmunity | Inflammation | Monocyte | Collagen | Rheumatoid arthritis | OSCAR | OSTEOCLAST-ASSOCIATED RECEPTOR | HUMAN DENDRITIC CELLS | SYNOVIAL-FLUID | DISEASE SEVERITY | PERIPHERAL-BLOOD | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | CUTTING EDGE | EXTRACELLULAR-MATRIX | NF-KAPPA-B | MYELOID CELLS-1 | Tumor Necrosis Factor-alpha - metabolism | Collagen Type I - metabolism | Dendritic Cells - immunology | Humans | Cells, Cultured | Receptors, Cell Surface - metabolism | Inflammation - immunology | Monocytes - immunology | Osteoclasts - cytology | Arthritis, Rheumatoid - pathology | Collagen Type II - metabolism | Cell Differentiation - immunology | Signal Transduction - immunology | Inflammation Mediators - metabolism | Interleukin-8 - metabolism | Synovial Fluid - cytology | Arthritis, Rheumatoid - immunology | Antibodies, Monoclonal - immunology | Monoclonal antibodies | Rheumatoid factor | Arthritis | Dendritic cells | Pathogenesis | Rodents | Collagen (type I) | Profiling | Transcription | Collagen (type II) | Leukocytes (mononuclear) | Synovial fluid | Signal transduction | Biomedical materials | Functional anatomy | Pathways | Biocompatibility | Interleukin 8 | Myeloid cells | Maturation | Cytokines | Ribonucleic acid--RNA | Patients | Survival | Osteoclastogenesis | Monocytes | Tumor necrosis factor | Ligands
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 2013, Volume 8, Issue 4, pp. 1195 - 1203
Journal Article
Journal Article
Journal Article