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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1434 - 17
Leptospirosis is the most emerging zoonotic disease of epidemic potential caused by pathogenic species of Leptospira. The bacterium invades the host system and... 
APOPTOSIS | CELLS | OUTER-MEMBRANE PROTEINS | ACTIVATION | INHIBITION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | LIPOPOLYSACCHARIDE | PROTEIN-PROTEIN INTERACTIONS | IDENTIFICATION | PREDICTION | Leptospirosis | Proteins | Pathogens | Infectious diseases | Outer membrane proteins | Localization | Protein interaction | Species | Membrane proteins | Zoonoses
Journal Article
Technology in Cancer Research & Treatment, ISSN 1533-0346, 7/2019, Volume 18, p. 1533033819858668
Objective: To identify the expression of kinetochore scaffold 1 (KNL1) in colorectal tumor tissues and to clarify the role of this gene in the proliferation... 
RECRUITMENT | PROTEIN | MICROTUBULE-BINDING | STATISTICS | cell growth | KNL1 | prognosis | Kinetochore scaffold 1 | ONCOLOGY | CANCER/TESTIS GENE D40/AF15Q14 | GASTRIC-CANCER | MITOTIC CHECKPOINT | protein expression | EXPRESSION | BUB1 | colorectal tumor | gene expression | OUTER KINETOCHORE
Journal Article
by Dou, Z and Prifti, DK and Gui, P and Liu, X and Elowe, S and Yao, XB
CELLS, ISSN 2073-4409, 03/2019, Volume 8, Issue 3, p. 278
Faithful chromosome segregation during mitosis is crucial for maintaining genome stability. The spindle assembly checkpoint (SAC) is a surveillance mechanism... 
localization | AURORA-B KINASE | PHOSPHO-REGULATION | CELL BIOLOGY | microtubule | MPS1 KINASE | kinase | kinetochore | MICROTUBULE ATTACHMENT | CENP-E | YEAST KINETOCHORE | CHROMOSOMAL PASSENGER COMPLEX | spindle assembly checkpoint (SAC) | MITOTIC CHECKPOINT | OUTER KINETOCHORE | UNATTACHED KINETOCHORES
Journal Article
Journal of cell science, ISSN 0021-9533, 10/2018, Volume 132, Issue 4, p. jcs219766
Chemically induced dimerisation (CID) uses small molecules to control specific protein-protein interactions. We employed CID dependent on the plant hormone... 
Checkpoint | Reconstitution | Spindle | Mitosis | Mps1 | Dimerisation | RECRUITMENT | SPC7/KNL1 | CELL BIOLOGY | CDC20 | ASSEMBLY CHECKPOINT | PROTEIN PHOSPHATASE 1 | MIS12 COMPLEX | REQUIRES | OUTER KINETOCHORE | CENP-C | Tools and Resources
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2019, Volume 47, Issue 1, pp. 468 - 479
Abstract The kinetochore is a proteinaceous complex that is essential for proper chromosome segregation. As a core member of the inner kinetochore, defects of... 
PLATFORM | FORMS | RECRUITMENT | COMPLEX | CHROMATIN | A NUCLEOSOMES | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPONENTS | CENTROMERIC NUCLEOSOME RECOGNITION | MOLECULAR-BASIS | OUTER KINETOCHORE | Structural Biology
Journal Article
Current Biology, ISSN 0960-9822, 11/2018, Volume 28, Issue 21, pp. R1250 - R1252
The Rod–Zw10–Zwilch complex localizes to kinetochores during mitosis. New studies reveal that this complex plays a critical role in driving the expansion of... 
OUTER PLATE | LOCALIZATION | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | CORONA | CENP-E | CHECKPOINT PROTEINS | CELL BIOLOGY | Medical colleges | Research | Chromosomes | Oncology, Experimental | Cancer
Journal Article
Current Biology, ISSN 0960-9822, 11/2018, Volume 28, Issue 21, pp. 3422 - 3429.e5
The Mad1-Mad2 heterodimer is the catalytic hub of the spindle assembly checkpoint (SAC), which controls M phase progression through a multi-subunit anaphase... 
aneuploidy | cell division | chromosome segregation | gene editing | spindle assembly checkpoint | OUTER PLATE | COMPLEX | PROTEIN | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROTUBULE ATTACHMENT | SPINDLE ASSEMBLY CHECKPOINT | MESSENGER-RNA DECAY | CHROMOSOME SEGREGATION | BUB1 | UNATTACHED KINETOCHORES | CELL BIOLOGY | Genetic transcription | Genes | Genomics | Cells
Journal Article
Current Biology, ISSN 0960-9822, 09/2018, Volume 28, Issue 17, pp. 2697 - 2704.e3
Kinesin-5 is a highly conserved homo-tetrameric protein complex responsible for crosslinking microtubules and pushing spindle poles apart. The budding yeast... 
Cin8 | PP1 | Dam1 | biosensor | cell division | kinetochore | mitosis | Kinesin-5 | Ndc80 | NDC80 COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROTUBULE-ATTACHMENT | MITOTIC SPINDLE | AURORA B | DASH COMPLEX | BUDDING YEAST KINETOCHORE | SACCHAROMYCES-CEREVISIAE | OUTER KINETOCHORE | MOTILE PROPERTIES | REVEALS | CELL BIOLOGY | Genetic research | Medical colleges | Crosslinked polymers | Phosphatases | Chromosomes | Kinesin
Journal Article