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Human Gene Therapy, ISSN 1043-0342, 06/2017, Volume 28, Issue 6, pp. 464 - 481
Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals.... 
Research Articles | photoreceptors | gene therapy | rods | retina | AAV | cones | MEDICINE, RESEARCH & EXPERIMENTAL | ADULT TELEOST RETINA | RECESSIVE RETINITIS-PIGMENTOSA | ADENOASSOCIATED VIRAL VECTORS | LEBER CONGENITAL AMAUROSIS | TARGETED DISRUPTION | PHASE-I TRIAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RHODOPSIN KNOCKOUT MOUSE | RESTORES VISION | GENETICS & HEREDITY | REPLACEMENT THERAPY | RETINAL GENE-THERAPY | Cytomegalovirus - chemistry | Dependovirus - genetics | Cricetulus | Genetic Vectors - administration & dosage | Intravitreal Injections | Rod Cell Outer Segment - metabolism | Green Fluorescent Proteins - genetics | Retinal Degeneration - metabolism | Rod Cell Outer Segment - pathology | Cell Differentiation | Transduction, Genetic - methods | Genes, Reporter | CHO Cells | Disease Models, Animal | Cytomegalovirus - genetics | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Dependovirus - metabolism | Genetic Vectors - chemistry | Retinal Degeneration - genetics | Genetic Vectors - metabolism | Mice, Transgenic | Organ Specificity | Animals | Genetic Engineering | Retinal Cone Photoreceptor Cells - cytology | Retinal Degeneration - therapy | Mice | Retinal Degeneration - pathology | Retinal Cone Photoreceptor Cells - metabolism | Injections, Intraocular | Neonates | Animal models | Gene transfer | Viruses | Retina | Segments | Rods | Vectors | Injection | Rod outer segment membranes | Modulators | Cones | Retinal degeneration | Photoreceptors | Degeneration | Gene therapy | Expression vectors
Journal Article
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 08/2016, Volume 34, Issue 6, pp. 429 - 440
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e59306
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 04/2011, Volume 22, Issue 7, pp. 921 - 930
The light-detecting outer segments of vertebrate photoreceptors are cilia. Like other cilia, all materials needed for assembly and maintenance are synthesized... 
Rhodopsin | Cones | opsins | Photoreceptors | Degeneration | Rods | Rod outer segment membranes | Cell body | Cilia | Golgi apparatus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2012, Volume 14, Issue 1, pp. 61 - 72
Using RNAi screening, proteomics, cell biological and mouse genetics approaches, we have identified a complex of nine proteins, seven of which are disrupted in... 
DISEASE GENES | REGULATOR | OUTER SEGMENT DEVELOPMENT | DISRUPTION | MKS1 | GENERATION | CILIOGENESIS | PROTEINS | CC2D2A | BODY | CELL BIOLOGY | Synthesis | RNA | Cilia and ciliary motion | Growth | Genetic aspects | Cellular signal transduction | Research | Properties | Membrane proteins
Journal Article