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Journal Article
Molecular Cell, ISSN 1097-2765, 02/2012, Volume 45, Issue 3, pp. 357 - 370
Journal Article
FEBS Letters, ISSN 0014-5793, 10/2008, Volume 582, Issue 23-24, pp. 3313 - 3319
The human obesity susceptibility gene, , encodes a protein that is homologous to the DNA repair AlkB protein. The AlkB family proteins utilize iron(II),... 
FTO | Oxidative demethylation | DNA/RNA repair | 1-meA | mFTO | 3-meT | 3-meU | 3-methyluracil | TFA | 1,N 6-ethenoadenine | BSA | α-KG | bovine serium albumin | 1-meG | mouse FTO | 3,N 4-ethenocytosine | HPLC | 3-methylcytosine | hFTO | ethylene diamine tetraacetic acid | isopropyl-β-d-thiogalactopyranoside | EDTA | α-ketoglutarate | human FTO | high performance liquid chromatography | trifluoroacetic acid | 3-meC | 3-methylthymine | 1-methyladenine | 1-methylguanine | IPTG | MES | 2-(N-morpholino)ethanesulfonic acid | HUMAN ALKB PROTEINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | CRYSTAL-STRUCTURES | BACTERIAL | ADULT OBESITY | LESIONS | CELL BIOLOGY | BIOPHYSICS | GENE | MASS | REPAIR ENZYME ALKB | ALKYLATION DAMAGE | Thymine - chemistry | Oxidation-Reduction | DNA, Single-Stranded - metabolism | Humans | Thymine - analogs & derivatives | Recombinant Proteins - chemistry | Substrate Specificity | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | DNA, Single-Stranded - chemistry | Mixed Function Oxygenases | Oxo-Acid-Lyases - chemistry | Animals | Proteins - metabolism | DNA Repair | Uracil - metabolism | Mice | Oxo-Acid-Lyases - metabolism | Proteins - chemistry | Methylation | Thymine - metabolism | Uracil - chemistry | RNA - metabolism | Uracil - analogs & derivatives | Proteins | Liquid chromatography | RNA | DNA | Ethylenediamines | oxidative demethylation | RNA repair
Journal Article
by Huang, Y and Yan, JL and Li, Q and Li, JF and Gong, SZ and Zhou, H and Gan, JH and Jiang, HL and Jia, GF and Luo, C and Yang, CG
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 01/2015, Volume 43, Issue 1, pp. 373 - 384
Two human demethylases, the fat mass and obesity-associated (FTO) enzyme and ALKBH5, oxidatively demethylate abundant N-6-methyladenosine (m(6)A) residues in... 
RNA DEMETHYLASE | OBESITY-ASSOCIATED FTO | MAXIMUM-LIKELIHOOD | MESSENGER-RNA | OXIDATIVE DEMETHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | PROMOTE PROTEIN STABILITY | CRYSTAL-STRUCTURES | HISTONE DEMETHYLASES | ALKYLATION DAMAGE
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 02/2017, Volume 359, Issue 4, pp. 687 - 692
Journal Article