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Angewandte Chemie International Edition, ISSN 1433-7851, 09/2016, Volume 55, Issue 39, pp. 12104 - 12108
An asymmetric organocatalytic domino oxa‐Michael/1,6‐addition reaction of ortho‐hydroxyphenyl‐substituted para‐quinone methides and isatin‐derived enoates has... 
organocatalysis | para-quinone methides | oxa-Michael addition | domino reactions | chromans | MICHAEL REACTION | DIELS-ALDER | EXPEDIENT ACCESS | SPIROCYCLIC OXINDOLES | ENANTIOSELECTIVE CONSTRUCTION | CHEMISTRY, MULTIDISCIPLINARY | CATALYTIC 1,6-CONJUGATE ADDITION/AROMATIZATION | MULTIPLE STEREOCENTERS | ALPHA-ALKYLATION | ACID-ESTERS | Synthesis | Oxalic acid | Quinone | Organic compounds
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 02/2016, Volume 57, Issue 5, pp. 591 - 594
A catalyst-free and green approach of sp C–H functionalization of methyl azaarenes with malononitrile and isatins for the synthesis of oxindole derivatives... 
On-water synthesis | Multicomponent reactions | Heterocyclic compounds | sp3 C–H functionalization | 3,3-Disubstituted oxindoles | C-H functionalization | SUBSTITUTED 3-HYDROXY-2-OXINDOLES | CHEMISTRY, ORGANIC | sp C-H functionalization | C(SP)-H FUNCTIONALIZATION | FACILE SYNTHESIS | CONSTRUCTION | INHIBITORS | BOND | DERIVATIVES
Journal Article
Organic Letters, ISSN 1523-7060, 09/2012, Volume 14, Issue 18, pp. 4922 - 4925
A new methodology was developed for the synthesis of enantiomerically enriched 3,3-disubstituted 3-chlorooxindoles 3 via a Michael addition of 3-chloroxindoles... 
1,4-ADDITIONS | OXINDOLES | CHEMISTRY, ORGANIC | FLUORINATION | 3-HYDROXY-2-OXINDOLES | NITROALKENES | MICHAEL ADDITION | Hydrocarbons, Chlorinated - chemistry | Stereoisomerism | Hydrocarbons, Chlorinated - chemical synthesis | Indoles - chemical synthesis | Molecular Structure | Catalysis | Indoles - chemistry
Journal Article
Organic Letters, ISSN 1523-7060, 11/2015, Volume 17, Issue 21, pp. 5168 - 5171
A highly efficient and practical one-pot sequential process, consisting of an organocatalytic enantioselective Friedel-Crafts-type addition of 4-nonsubstituted... 
ISATIN-DERIVED KETIMINES | HIGHLY ENANTIOSELECTIVE SYNTHESIS | MANNICH REACTION | NATURAL-PRODUCTS | QUATERNARY STEREOCENTERS | TERTIARY STEREOCENTERS | NITROOLEFINS | CHEMISTRY, ORGANIC | N-BOC KETIMINES | 3-SUBSTITUTED OXINDOLES | MICHAEL ADDITION
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 05/2011, Volume 76, Issue 10, pp. 4008 - 4017
An organocatalytic asymmetric Michael addition reaction of 3-substituted oxindoles to protected 2-amino-1-nitroethenes has been developed. The reaction is... 
GUIDED ISOLATION | NATURAL-PRODUCTS | STEREOCENTERS | CONSTRUCTION | NITROOLEFINS | CHEMISTRY, ORGANIC | INHIBITORS | CONJUGATE ADDITIONS | QUATERNARY | 3-SUBSTITUTED OXINDOLES | ALKALOIDS | Amines - chemistry | Indans - chemistry | Indoles - chemical synthesis | Catalysis | Indoles - chemistry | Nitro Compounds - chemistry
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 04/2013, Volume 24, Issue 7, pp. 343 - 356
3-Amino-2-oxindoles bearing tetra-substituted stereocenter are very important constituents of many bioactive and pharmaceutical agents. In the last few years,... 
ALPHA-AMINATION | ISOTHIOCYANATO OXINDOLES | POTENT | ENANTIOSELECTIVE SYNTHESIS | CONSTRUCTION | CHEMISTRY, PHYSICAL | BAYLIS-HILLMAN CARBONATES | PICTET-SPENGLER REACTIONS | KETIMINES | HIGHLY EFFICIENT | SPIROOXINDOLES | Synthesis | Organic compounds
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 07/2016, Volume 81, Issue 13, pp. 5362 - 5369
The first asymmetric synthesis of spiro-gamma-lactam oxindoles bearing three stereocenters is reported. One-pot thiol-Michael/Mannich/lactamization reactions... 
N-HETEROCYCLIC CARBENE | ISOTHIOCYANATO OXINDOLES | ENANTIOSELECTIVE SYNTHESIS | SULFA-MICHAEL ADDITION | SELECTIVE INHIBITORS | CHEMISTRY, ORGANIC | MULTICOMPONENT CASCADE | STEREOSELECTIVE-SYNTHESIS | HIGHLY EFFICIENT | 3-COMPONENT DOMINO REACTION | CASCADE REACTION
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 01/2019, Volume 25, Issue 4, pp. 966 - 970
A copper‐catalyzed trifunctionalization of alkynes that provides rapid access to oxindoles bearing a geminal diboronate side chain, highlighted by the... 
oxindoles | bis-borylation | copper | trifunctionalization | alkynes | EFFICIENT ROUTE | CARBOBORATION | TERMINAL ALKYNES | BORONIC ESTERS | CHEMISTRY, MULTIDISCIPLINARY | FREE DIBORATION | BORYLSTANNYLATION | CONSTRUCTION | SELECTIVE SYNTHESIS | BORYLATION | CARBOXYLIC-ACIDS | Hydroboration | Catalysis | Copper | Substrates | Alkynes | Bearing
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 04/2019, Volume 84, Issue 7, pp. 4009 - 4016
The synthesis of spirooxindoles bearing tetrahydro-4H-cyclopenta[b]furan framework was established starting from isatin-derived aldehydes and 2 equiv of... 
DIELS-ALDER | POTENT | DESIGN | ORGANOCATALYTIC MICHAEL ADDITION | ENANTIOSELECTIVE SYNTHESIS | ISATYLIDENE-3-ACETALDEHYDES APPLICATION | 3+3 ANNULATION | OXINDOLES | CHEMISTRY, ORGANIC | ISATIN-DERIVED ENALS | ACCESS
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 01/2018, Volume 24, Issue 1, pp. 2 - 2
Tetrahydrothiophenes with four contiguous stereocenters were constructed by an unprecedented organocatalytic asymmetric one‐pot... 
organocatalysis | asymmetric synthesis | rearrangement | spiro-tetrahydrothiophene oxindoles | Michael-Henry reaction | Cascade chemical reactions | Asymmetric synthesis | Chemical synthesis | Scaffolds
Journal Article
Organic Letters, ISSN 1523-7060, 05/2018, Volume 20, Issue 10, pp. 2888 - 2891
The highly enantioselective preparation of spirooxindoles bearing alpha,alpha-disubstituted alpha-amino-beta-keto esters was achieved through [4 + 1]... 
CYCLOADDITION | CATALYSIS | SPIROOXINDOLE DERIVATIVES | CASCADE REACTIONS | SPIROPYRAZOLONES | MALEIMIDES | CHEMISTRY, ORGANIC | 4 CONSECUTIVE STEREOCENTERS | SPIROCYCLIC OXINDOLES | BIOXINDOLES | ALKYNES
Journal Article