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Journal of Vascular Surgery, ISSN 0741-5214, 2016, Volume 65, Issue 4, pp. 1171 - 1179.e1
Background Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains... 
Surgery | PATHOGENESIS | SURGERY | APOPTOSIS | METABOLITES | OBESITY | INCREASE | VASCULAR DYSFUNCTION | DISEASE | ATHEROSCLEROSIS | INTRALUMINAL THROMBUS | PERIPHERAL VASCULAR DISEASE | MICE | Cell Adhesion Molecules - genetics | Aortic Aneurysm, Abdominal - immunology | T-Lymphocytes - enzymology | Peptide Hydrolases - genetics | Cytokines - analysis | Humans | Adipocytes - enzymology | Adipose Tissue - immunology | Antigens, CD - genetics | Necrosis | Antigens, CD - analysis | T-Lymphocytes - pathology | Cytokines - genetics | Adipocytes - immunology | Aortic Aneurysm, Abdominal - pathology | Macrophages - immunology | Neutrophils - pathology | Mast Cells - immunology | Macrophages - pathology | Neutrophils - enzymology | GPI-Linked Proteins - analysis | Adipose Tissue - pathology | Neutrophils - immunology | Aortic Aneurysm, Abdominal - genetics | Ceramides - analysis | Peptide Hydrolases - analysis | Mast Cells - enzymology | Adipocytes - pathology | Macrophages - enzymology | Gene Expression Regulation, Enzymologic | Aortic Aneurysm, Abdominal - enzymology | Mast Cells - pathology | Cell Adhesion Molecules - analysis | T-Lymphocytes - immunology | Adipose Tissue - enzymology | GPI-Linked Proteins - genetics | Adipose tissues | Proteases | Ceramides | Aneurysms | Plant lipids | Molecular biology | Cardiovascular agents | Immunohistochemistry | Analysis | Genetic research | T cells | Gene expression | Mass spectrometry | Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kirurgi
Journal Article
Journal Article
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 1/2018, Volume 41, Issue 1, pp. 49 - 57
The Native American Pima population has the highest incidence of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) of any reported population, but... 
Human Genetics | Biochemistry, general | Pediatrics | Internal Medicine | Medicine & Public Health | Metabolic Diseases | MEDICINE, RESEARCH & EXPERIMENTAL | PROFILES | OBESITY | PIMA-INDIANS | METABOLISM | ACID BETA-OXIDATION | INSULIN-RESISTANCE | FATTY-ACID | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | YOUTH | ACYLCARNITINES | DYSFUNCTION | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Rhabdomyolysis - enzymology | Lipid Metabolism, Inborn Errors - genetics | Liver - enzymology | Diabetes Mellitus, Type 2 - genetics | Obesity, Abdominal - physiopathology | Mice, 129 Strain | Insulin - blood | Lipid Metabolism, Inborn Errors - enzymology | Adiposity | Lipid Metabolism, Inborn Errors - pathology | Non-alcoholic Fatty Liver Disease - enzymology | Rhabdomyolysis - pathology | Disease Models, Animal | Acyl-CoA Dehydrogenase - genetics | Genetic Predisposition to Disease | Muscle, Skeletal - enzymology | Mitochondria, Muscle - enzymology | Non-alcoholic Fatty Liver Disease - genetics | Mitochondria, Muscle - pathology | Mice, Inbred C57BL | Obesity, Abdominal - enzymology | Abdominal Fat - physiopathology | Mice, Knockout | Lipid Metabolism, Inborn Errors - physiopathology | Phenotype | Animals | Diabetes Mellitus, Type 2 - physiopathology | Rhabdomyolysis - genetics | Abdominal Fat - enzymology | Insulin Resistance - genetics | Diabetes Mellitus, Type 2 - pathology | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Obesity, Abdominal - genetics | Type 2 diabetes | Medical colleges | Blood sugar monitoring | Analysis | Muscles | Insulin resistance | Oxidoreductases | Native Americans | Glucose tolerance tests | Investigations | Risk factors | Genetic polymorphisms | Adipose tissue | Diabetes mellitus | Liver | Inflammation | Rhabdomyolysis | C-Terminus | Insulin | Minority & ethnic groups | Skeletal muscle | Acyl-CoA dehydrogenase | Studies | Glucose tolerance | Mitochondria | Dehydrogenation | Diabetes | Diabetes mellitus (non-insulin dependent) | type 2 diabetes mellitus | Pima Indians | Recurrent rhabdomyolysis | ACAD10 | acyl-coA dehydrogenases
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2013, Volume 33, Issue 4, pp. 839 - 846
Journal Article
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 2015, Volume 26, Issue 4, pp. 212 - 220
Journal Article
Atherosclerosis, ISSN 0021-9150, 2014, Volume 236, Issue 2, pp. 321 - 326
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 11/2013, Volume 305, Issue 9, pp. H1344 - H1353
Ca+ mishandling due to impaired activity of cardiac sarco(endo) plasmic reticulum Ca2+ ATPase (SERCA2a) has been associated with the development of left... 
Heart | Oxidative stress | Calcium | Metabolic syndrome | Sarco(endo)plasmic reticulum Ca | ATPase 2a | SUCROSE-FED RATS | CARDIAC CONTRACTILE DYSFUNCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | calcium | HEART-FAILURE | HYPERTRIGLYCERIDEMIC RATS | ANTIOXIDANT ENZYMES | heart | metabolic syndrome | VENTRICULAR DIASTOLIC DYSFUNCTION | SARCOPLASMIC-RETICULUM CA2 | sarco(endo) plasmic reticulum Ca2+ ATPase 2a | INSULIN-RESISTANCE | RYANODINE RECEPTORS | PERIPHERAL VASCULAR DISEASE | TYPE-2 DIABETES-MELLITUS | oxidative stress | Phosphorylation | Reactive Oxygen Species - metabolism | Rats, Wistar | Calcium - metabolism | Male | Metabolic Syndrome - chemically induced | Myocytes, Cardiac - enzymology | Metabolic Syndrome - blood | Hyperinsulinism - enzymology | Ventricular Dysfunction, Left - enzymology | Dietary Sucrose | Hyperinsulinism - blood | Calcium Signaling | Disease Models, Animal | Calcium-Binding Proteins - metabolism | Metabolic Syndrome - enzymology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Oxidation-Reduction | Down-Regulation | Insulin Resistance | Rats | Ventricular Dysfunction, Left - etiology | Antioxidants - pharmacology | Obesity, Abdominal - enzymology | Hypertriglyceridemia - blood | Hypertriglyceridemia - enzymology | Obesity, Abdominal - blood | Animals | Myocytes, Cardiac - drug effects | Oxidative Stress - drug effects | Heart cells | Physiological aspects | Insulin resistance | Metabolic diseases | Research | Health aspects
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 29, pp. 12339 - 12350
Chronic inflammation may contribute to insulin resistance via molecular cross-talk between pathways for pro-inflammatory and insulin signaling. Interleukin 1... 
PHOSPHATIDYLINOSITOL 3-KINASE ACTIVITY | SIGNALING PATHWAYS | NITRIC-OXIDE PRODUCTION | ENDOTHELIAL DYSFUNCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLECKSTRIN HOMOLOGY DOMAIN | TOLL-LIKE RECEPTORS | IKK-BETA | IMPAIRED REGULATION | NF-KAPPA-B | RECIPROCAL RELATIONSHIPS | Glucose Intolerance - metabolism | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Diet, High-Fat - adverse effects | Endothelium, Vascular - drug effects | Male | Muscle, Skeletal - metabolism | Endothelium, Vascular - enzymology | Glucose Intolerance - prevention & control | Subcutaneous Fat, Abdominal - enzymology | Glucose Intolerance - etiology | Muscle, Skeletal - drug effects | Obesity - etiology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Glucose Intolerance - physiopathology | Biomarkers - metabolism | Insulin - pharmacology | Muscle, Skeletal - enzymology | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Insulin Resistance | Obesity - physiopathology | Biomarkers - blood | Organ Specificity | Hemizygote | Hypoglycemic Agents - pharmacology | Mice, Knockout | Subcutaneous Fat, Abdominal - drug effects | Animals | Endothelium, Vascular - metabolism | Diet, Fat-Restricted | Glucose Clamp Technique | Subcutaneous Fat, Abdominal - metabolism | Crosses, Genetic | IRAK-1 | inflammation | muscle | Metabolism | Akt PKB | glucose tolerance | insulin resistance
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 11/2016, Volume 37, pp. 76 - 82
Eicosapentaenoic acid (EPA), a n-3 long-chain polyunsaturated fatty acid, has been reported to have beneficial effects in obesity-associated metabolic... 
Fatty acid oxidation | N-3 PUFAs | Browning | Mitochondrial biogenesis | Lipogenesis | EPA | 3T3-L1 ADIPOCYTES | BETA-OXIDATION | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED OBESITY | INSULIN SENSITIVITY | ETHYL-ESTER | WHITE ADIPOSE-TISSUE | NUTRITION & DIETETICS | LIPID DROPLET FORMATION | GENE-EXPRESSION | POLYUNSATURATED FATTY-ACIDS | Fatty Acid Synthases - antagonists & inhibitors | Mitochondrial Dynamics | Carnitine O-Palmitoyltransferase - chemistry | Carnitine O-Palmitoyltransferase - genetics | Acyl-CoA Oxidase - metabolism | Fatty Acid Synthases - metabolism | Humans | Adipocytes, White - enzymology | Diacylglycerol O-Acyltransferase - antagonists & inhibitors | Organelle Biogenesis | Osmolar Concentration | Adipocytes, Beige - pathology | Subcutaneous Fat, Abdominal - enzymology | Carnitine O-Palmitoyltransferase - metabolism | Female | Adipocytes, Beige - enzymology | Fatty Acid Synthases - genetics | Adipogenesis | Biomarkers - metabolism | Body Mass Index | Adipocytes, Beige - metabolism | Cells, Cultured | Eicosapentaenoic Acid - metabolism | Lipid Metabolism | Acyl-CoA Oxidase - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | Stearoyl-CoA Desaturase - genetics | Gene Expression Regulation, Enzymologic | Adipocytes, White - pathology | Subcutaneous Fat, Abdominal - pathology | Diacylglycerol O-Acyltransferase - genetics | Energy Metabolism | Stearoyl-CoA Desaturase - metabolism | Acyl-CoA Oxidase - chemistry | Diacylglycerol O-Acyltransferase - metabolism | Subcutaneous Fat, Abdominal - metabolism | Adipocytes, White - metabolism | Oxidases | Obesity | Unsaturated fatty acids | RNA | Genes | Biosynthesis | Gene expression | Omega-3 fatty acids
Journal Article
Journal Article
Journal Article