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oct-2 protein (126) 126
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PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0144667
Ro 31-8220 is a potent protein kinase C (PKC) inhibitor belonging to the chemical class of bisindolylmaleimides (BIMs). Various PKC-independent effects of Ro... 
GLYCOGEN-SYNTHASE | GF 109203X | DRUG-INTERACTIONS | RAT ADIPOCYTES | MULTIDISCIPLINARY SCIENCES | N-TERMINAL KINASE | SELECTIVE INHIBITORS | S6 KINASE | MULTIDRUG-RESISTANCE | POTENT INHIBITORS | CELL-LINE | Green Fluorescent Proteins - metabolism | Organic Cation Transport Proteins - metabolism | Humans | Enzyme Inhibitors - pharmacology | Maleimides - pharmacology | Organic Cation Transporter 1 - metabolism | Green Fluorescent Proteins - genetics | Protein Kinase C - antagonists & inhibitors | Organic Cation Transporter 2 | Organic Cation Transporter 1 - genetics | Dose-Response Relationship, Drug | Microscopy, Confocal | Organic Cation Transport Proteins - antagonists & inhibitors | Protein Kinase C - metabolism | Tetraethylammonium - metabolism | HEK293 Cells | Organic Cation Transporter 1 - antagonists & inhibitors | Cell Line, Tumor | Indoles - pharmacology | Organic Cation Transport Proteins - genetics | Enzyme inhibitors | Heterocyclic compounds | Patient outcomes | Dosage and administration | Ion channels | Protein kinases | Health aspects | Drugs | Diabetic retinopathy | Protein kinase C | Staurosporine | Liver | Chelerythrine | Tetraethylammonium | Oct-2 protein | Structure-activity relationships | Kinases | Drug resistance | Blockage | Proteins | Rodents | Penicillin | Organic cation transporter | Polypeptides | Substrate inhibition | Breast cancer | Chemicals | Prescription drugs | Inhibitors | Extrusion | Cations | Diabetes | Transporter | Cancer | Bile | Life Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e22163
Journal Article
Biological Chemistry, ISSN 1431-6730, 02/2017, Volume 398, Issue 2, pp. 237 - 249
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 6659 - 10
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0202706
Efavirenz (EFV) is a non-nucleoside reverse transcriptase inhibitor used in first-line combination antiretroviral therapy (cART). It is usually administered... 
Rats, Wistar | Area Under Curve | Humans | Half-Life | Reverse Transcriptase Inhibitors - pharmacology | Male | Metformin - metabolism | Kidney - metabolism | Reverse Transcriptase Inhibitors - pharmacokinetics | Organic Cation Transport Proteins - antagonists & inhibitors | HEK293 Cells | Madin Darby Canine Kidney Cells | Reverse Transcriptase Inhibitors - urine | Organic Cation Transport Proteins - metabolism | Metformin - pharmacology | Rats | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Lamivudine - pharmacokinetics | Renal Elimination | Animals | Benzoxazines - pharmacology | Dogs | Cimetidine - pharmacology | ROC Curve | Lamivudine - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Lamivudine - urine | Antiviral agents | Complications and side effects | Kidneys | Analysis | Lamivudine | Dosage and administration | Pharmacokinetics | Health aspects | Efavirenz | Intravenous administration | Renal function | RNA-directed DNA polymerase | Oct-2 protein | Retention | Accumulation | Proteins | Consortia | MDR1 protein | Toxicology | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Drug therapy | P-Glycoprotein | Calcein | Urine | Efflux | Antiretroviral drugs | Excretion | Cimetidine | Pharmacology | Substrates | Antiretroviral therapy | Prescription drugs | Non-nucleoside reverse transcriptase inhibitors | Inhibitors | Pharmacy | Nucleosides | Extrusion | In vivo methods and tests | Metformin | Transport | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Scientific Reports, ISSN 2045-2322, 2015, Volume 5, Issue 1, pp. 16702 - 16702
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169480 - e0169480
Pyrethroids are widely-used chemical insecticides, to which humans are commonly exposed, and known to alter functional expression of drug metabolizing enzymes.... 
ORGANIC CATION TRANSPORTER-2 | RESISTANCE PROTEIN ABCG2 | SODIUM-CHANNELS | MULTIDISCIPLINARY SCIENCES | HUMAN MDR1 | PREGNANE-X-RECEPTOR | RISK-ASSESSMENT | RAT NA(V)1.6 | INSECTICIDES | P-GLYCOPROTEIN | HEPATIC DRUG | Solute Carrier Proteins - metabolism | Cell Line | Pyrethrins - toxicity | Humans | Organic Cation Transporter 1 - metabolism | Structure-Activity Relationship | Allethrin - chemistry | HEK293 Cells - drug effects | Organic Cation Transporter 1 - genetics | Pyrethrins - chemistry | Solute Carrier Proteins - antagonists & inhibitors | Allethrin - toxicity | Pesticides - toxicity | Organic Cation Transporter 1 - antagonists & inhibitors | ATP-Binding Cassette Transporters - metabolism | Pesticides - chemistry | Toxicity Tests | Dopamine - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Physiological aspects | Drug resistance in microorganisms | Insecticides | Research | Regulators | Molecular structure | Toxicity | Material requirements planning | Pyrethroids | Oct-2 protein | Structure-activity relationships | Molecular weight | Proteins | Neurotoxicity | Tetramethrin | Anions | Insecticide resistance | Agrochemicals | Rodents | Inhibition | Protein transport | P-Glycoprotein | Enzymes | Organic cation transporter | Multidrug resistance | Pesticides | Detoxification | Glycoprotein | Breast cancer | Exposure | Mammals | Organic anion transporting polypeptide | Acids | Extrusion | Transporter | Lipophilicity | Cancer | Index Medicus | Life Sciences | Toxicology | Ecology, environment | Health
Journal Article
Journal Article
DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 08/2019, Volume 47, Issue 8, pp. 802 - 808
Journal Article