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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 28, pp. E6640 - E6649
Endosomes have emerged as a central hub and pathogenic driver of Alzheimer's disease (AD). The earliest brain cytopathology in neurodegeneration, occurring... 
Histone deacetylase | Trichostatin A | Amyloid beta | ApoE4 | exchanger | Na+/H+ exchanger | CHRISTIANSON SYNDROME | HUMAN BRAIN | trichostatin A | MULTIDISCIPLINARY SCIENCES | SPORADIC ALZHEIMERS-DISEASE | histone deacetylase | SYNAPTIC PLASTICITY | amyloid beta | APOLIPOPROTEIN-E | LYSOSOMAL DYSFUNCTION | DOWN-SYNDROME | A-BETA | GENE-EXPRESSION | PRECURSOR PROTEIN | Microcephaly - genetics | Epigenesis, Genetic | Humans | Astrocytes - pathology | Epilepsy - metabolism | Endosomes - metabolism | Alzheimer Disease - pathology | Intellectual Disability - metabolism | Amyloid beta-Peptides - genetics | Amyloid beta-Peptides - metabolism | Ataxia - drug therapy | Genetic Diseases, X-Linked - genetics | Ataxia - genetics | Ataxia - metabolism | Microcephaly - drug therapy | Ataxia - pathology | Ocular Motility Disorders - pathology | Tumor Suppressor Proteins - metabolism | Apolipoprotein E4 - metabolism | Endosomes - genetics | Histone Deacetylases - genetics | Ocular Motility Disorders - metabolism | Intellectual Disability - pathology | Alzheimer Disease - drug therapy | Receptors, LDL - metabolism | Mice, Knockout | Genetic Diseases, X-Linked - pathology | Epilepsy - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Mice | Astrocytes - metabolism | Hydrogen-Ion Concentration | Apolipoprotein E4 - genetics | Ocular Motility Disorders - genetics | Intellectual Disability - genetics | Sodium-Hydrogen Exchangers - metabolism | Genetic Diseases, X-Linked - drug therapy | Microcephaly - pathology | Tumor Suppressor Proteins - genetics | Epilepsy - genetics | Sodium-Hydrogen Exchangers - genetics | Receptors, LDL - genetics | Microcephaly - metabolism | Histone Deacetylases - metabolism | Endosomes - pathology | Genetic Diseases, X-Linked - metabolism | Intellectual Disability - drug therapy | Ocular Motility Disorders - drug therapy | Animals | Alzheimer Disease - metabolism | Alzheimer Disease - genetics | Epilepsy - pathology | Physiological aspects | Epigenetic inheritance | Glycoproteins | Genetic aspects | Observations | Astrocytes | Protons | Brain | Membranes | Transcription | Gene regulation | Trafficking | Cognitive ability | Acidification | pH effects | Neuronal-glial interactions | Risk factors | Proteins | Apolipoprotein E | Neurodegeneration | Compartments | Down-regulation | Alzheimer's disease | Plaques | Translocation | Pathogens | Apolipoprotein E4 | Therapeutic applications | Na+/H+-exchanging ATPase | Risk analysis | Apolipoproteins | Nuclear transport | Alleles | Epigenetics | Cytopathology | Receptor density | Mutation | Alzheimers disease | Endosomes | Index Medicus | Biological Sciences | PNAS Plus | H+ exchanger | Na+
Journal Article
Journal Article
Pediatrics, ISSN 0031-4005, 03/2009, Volume 123, Issue 3, pp. e534 - e541
OBJECTIVES. Alternating hemiplegia of childhood is a predominantly sporadic neurodevelopmental syndrome of uncertain etiology. In more than 3 decades since its... 
Ocular movements | Migraine | Movement disorder | Alternating hemiplegia | Seizures | ocular movements | migraine | FLUNARIZINE | alternating hemiplegia | TOPIRAMATE | ATP1A2 | DEFICIENCY | SPECT | ENCEPHALOPATHY | movement disorder | NO MUTATIONS | seizures | MITOCHONDRIAL DYSFUNCTION | PEDIATRICS | CEREBELLAR ATROPHY | Age Factors | Follow-Up Studies | Humans | Tomography, Emission-Computed, Single-Photon | Ataxia - etiology | Child, Preschool | Hemiplegia - etiology | Infant | Male | Electroencephalography | Positron-Emission Tomography | Psychotropic Drugs - therapeutic use | Psychotropic Drugs - adverse effects | Young Adult | Hemiplegia - diagnosis | Ocular Motility Disorders - diagnosis | Cognition Disorders - etiology | Female | Child | Ocular Motility Disorders - etiology | Serotonin Uptake Inhibitors - therapeutic use | Magnetic Resonance Angiography | Serotonin Uptake Inhibitors - adverse effects | Seizures - diagnosis | Treatment Outcome | Ataxia - diagnosis | Cognition Disorders - diagnosis | Magnetic Resonance Imaging | Ocular Motility Disorders - drug therapy | Neurologic Examination | Adolescent | Seizures - etiology | Brain - pathology | Cohort Studies | Genotype & phenotype | Pediatrics | Medical treatment | Paralysis | Neurological disorders | Clinical outcomes | Children & youth | Index Medicus | Abridged Index Medicus
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Journal Article
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Journal Article