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Hepatology, ISSN 0270-9139, 11/2012, Volume 56, Issue 5, pp. 1902 - 1912
Clinical trials and animal models suggest that infusion of bone marrow cells (BMCs) is effective therapy for liver fibrosis, but the underlying mechanisms are... 
RECRUITMENT | HEPATIC STELLATE CELLS | RETINOIC ACID | MACROPHAGES | INFLAMMATION | RECEPTOR | SUPPRESSOR-CELLS | DIFFERENTIATION | MYELOID CELLS | GASTROENTEROLOGY & HEPATOLOGY | T-CELLS | Interleukin-1 - genetics | Liver Cirrhosis - immunology | T-Lymphocytes, Regulatory - metabolism | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Actins - metabolism | Hepatic Stellate Cells - metabolism | Male | RNA, Messenger - metabolism | Liver Cirrhosis - chemically induced | T-Lymphocytes, Regulatory - immunology | Hepatic Stellate Cells - immunology | Forkhead Transcription Factors - metabolism | Bone Marrow Cells - immunology | Bone Marrow Transplantation | Liver Cirrhosis - metabolism | Statistics, Nonparametric | Interleukin-10 - metabolism | Chemokine CCL2 - metabolism | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Cell Communication | Chemokine CCL2 - genetics | Mice, Transgenic | Transforming Growth Factor beta1 - genetics | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Mice, Nude | Liver Cirrhosis - pathology | Mice | CD11b Antigen - metabolism | Interleukin-10 - immunology | Bone Marrow Cells - metabolism | CD4 Antigens - metabolism | Bone marrow | Cytokines | Liver cirrhosis | Hepatology | Index Medicus | retinoic acid | hepatic stellate cell | regulatory T cell | interleukin-6
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 198, pp. 55 - 61
Inhaled antibiotics, such as tobramycin, for the treatment of pulmonary infections are associated with the increase in life expectancy seen in cystic fibrosis... 
Pseudomonas aeruginosa | Alginate | DNase | Tobramycin | Nanoparticle | Cystic fibrosis sputum | CHITOSAN/ALGINATE NANOPARTICLES | VIVO | DRUG-DELIVERY | SPUTUM | LUNG INFECTION | CHEMISTRY, MULTIDISCIPLINARY | BACTERIAL BIOFILMS | DEXTRAN SULFATE | IN-VITRO CHARACTERIZATION | GALLERIA-MELLONELLA | OCULAR DELIVERY | PHARMACOLOGY & PHARMACY | Recombinant Proteins - therapeutic use | Nanoparticles - chemistry | Humans | Pseudomonas aeruginosa - growth & development | Tobramycin - pharmacology | Deoxyribonuclease I - therapeutic use | Tobramycin - administration & dosage | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Deoxyribonuclease I - chemistry | Deoxyribonuclease I - pharmacology | Nanoparticles - therapeutic use | Anti-Bacterial Agents - chemistry | Adult | Tobramycin - chemistry | Glucuronic Acid - chemistry | Tobramycin - therapeutic use | Pseudomonas Infections - drug therapy | Recombinant Proteins - chemistry | Treatment Outcome | DNA - metabolism | Hexuronic Acids - chemistry | Pseudomonas aeruginosa - drug effects | Recombinant Proteins - pharmacology | Deoxyribonuclease I - administration & dosage | Chemistry, Pharmaceutical | Recombinant Proteins - administration & dosage | Sputum - metabolism | Chitosan - chemistry | Alginates - chemistry | Anti-Bacterial Agents - pharmacology | Nanoparticles - administration & dosage | Anti-Bacterial Agents - administration & dosage | Cystic Fibrosis - drug therapy | Dornase alfa | Analysis | Cystic fibrosis | Polymers | Health aspects | Index Medicus
Journal Article
Investigative ophthalmology & visual science, ISSN 0146-0404, 06/2018, Volume 59, Issue 7, pp. 3115 - 3123
PURPOSE. To investigate whether histone deacetylase (HDAC) activity is associated with postoperative scarring and to evaluate the effect of HDAC inhibition by... 
Trabeculectomy | Histone deacetylase inhibitor | Trichostatin A | Fibrosis | OCULAR SURFACE | SCAR FORMATION | trichostatin A | HISTONE DEACETYLASE INHIBITION | FILTERING SURGERY | INJURY | trabeculectomy | INTRAOCULAR-PRESSURE | PREVENTS | GLAUCOMA FILTRATION SURGERY | histone deacetylase inhibitor | MOUSE MODEL | GROWTH | OPHTHALMOLOGY | fibrosis | Index Medicus
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 11/2017, Volume 135, Issue 11, pp. 1147 - 1155
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167200 - e0167200
In humans suffering from pulmonary disease and a mouse model, transient receptor potential vanilloid 4 (TRPV4) channel activation contributes to fibrosis. As a... 
CELLS | ACTIVATION | TGF-BETA | INHIBITION | MICE LACKING TRPV4 | MULTIDISCIPLINARY SCIENCES | LUNG INJURY | CHANNELS | SENSATION | MYOFIBROBLAST DIFFERENTIATION | Inflammation - pathology | Interleukin-6 - genetics | Gene Knockout Techniques | Vascular Endothelial Growth Factor A - genetics | TRPV Cation Channels - deficiency | TRPV Cation Channels - genetics | Actins - genetics | Gene Expression Regulation - drug effects | TRPV Cation Channels - metabolism | Eye Burns - complications | Eye Burns - pathology | Animals | Cornea - drug effects | Transforming Growth Factor beta - genetics | Eye Burns - chemically induced | Fibrosis | Cornea - pathology | Corneal Opacity - complications | Mice | Alkalies - pharmacology | Eye Burns - genetics | Genetically modified mice | Cornea | Research | Risk factors | Immunohistochemistry | Animal models | Transparency | Syngeneic grafts | Transforming growth factor | Interleukin | Bone marrow transplantation | Smooth muscle | Transplantation | Activation | Leukocytes | Macrophages | Interleukin 6 | Transient receptor potential proteins | Actin | Rodents | Bone marrow | Fibroblasts | Leukocytes (polymorphonuclear) | Bioindicators | Vascular endothelial growth factor | Medical research | Wound healing | Cytokines | Lung diseases | Muscles | Cultures | Inflammation | Gene expression | Burning | Immune systems | Polymerase chain reaction | White blood cells | Scars | Incineration | Monocyte chemoattractant protein | Collagen | Biomarkers | Infiltration | Laboratory animals | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article
Journal Article
Journal Article
Cell and Tissue Banking, ISSN 1389-9333, 9/2013, Volume 14, Issue 3, pp. 475 - 488
Journal Article