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Nucleic Acids Research, ISSN 0305-1048, 01/2018, Volume 46, Issue D1, pp. D762 - D769
Abstract The UCSC Genome Browser (https://genome.ucsc.edu) provides a web interface for exploring annotated genome assemblies. The assemblies and annotation... 
NETWORK | OFF-TARGET | INTEGRATION | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPREHENSIVE RESOURCE | KEGG | CORUM | PROTEINS | CURATION | BASE | Database Issue
Journal Article
BioTechniques, ISSN 0736-6205, 11/2018, Volume 65, Issue 5, pp. 259 - 267
GUIDE-seq was developed to detect CRISPR/Cas9 off-target. However, as originally reported, it was associated with a high level of nonspecific amplification. In... 
TEG-seq | CRISPR/cas9 | off-target | gene editing | GUIDE-seq
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2018, Volume 46, Issue W1, pp. W242 - W245
Abstract CRISPOR.org is a web tool for genome editing experiments with the CRISPR-Cas9 system. It finds guide RNAs in an input sequence and ranks them... 
CRISPR-CAS9 | DESIGN | OFF-TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOOL | Web Server Issue
Journal Article
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 5, pp. 247 - 256
CRISPR/Cas9 is the latest tool introduced in the field of genome engineering and is so far the best genome-editing tool as compared to its precedents such as,... 
Off-target | CRISPR/Cas9 | Autophagy | PAM | gRNA
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 186 - 191
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 02/2018, Volume 19, Issue 2, pp. 67 - 80
Exciting new technologies are often self-limiting in their rollout, as access to state-of-the-art instrumentation or the need for years of hands-on experience,... 
DRUG | OFF-TARGET | DNA | GENETICS & HEREDITY | RNAI SCREENS | LARGE-SCALE | SGRNA DESIGN | CAS9 | IDENTIFICATION | GENOME | REVEALS | Genes | Genomics | Genetic screening | CRISPR | New technology
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 05/2016, Volume 17, Issue 5, pp. 300 - 312
Journal Article
RNA-A PUBLICATION OF THE RNA SOCIETY, ISSN 1355-8382, 07/2006, Volume 12, Issue 7, pp. 1179 - 1187
Transfected siRNAs and miRNAs regulate numerous transcripts that have only limited complementarity to the active strand of the RNA duplex. This process... 
POSTTRANSCRIPTIONAL REGULATION | MOTIFS | RNAi | off-target | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | siRNA | MICRORNAS | IMPACT | EVOLUTION | MESSENGER-RNA | REPRESSION | shRNA | ELEGANS | GENE-EXPRESSION | seed region | miRNA
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 10/2019
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 05/2011, Volume 12, Issue 5, pp. 329 - 340
Journal Article