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PLOS ONE, ISSN 1932-6203, 08/2008, Volume 3, Issue 8, pp. e2863 - e2863
Journal Article
Glia, ISSN 0894-1491, 01/2018, Volume 66, Issue 1, pp. 175 - 190
Brain nerve fibers are insulated by myelin which is produced by oligodendrocytes. Defects in myelination are increasingly recognized as a common pathology... 
white matter integrity | Ulk4 | knockout mice | hypomyelination | oligodendrogenesis | TRANSCRIPTION FACTOR OLIG2 | NERVOUS-SYSTEM | WHITE-MATTER | MYELIN FORMATION | CONDITIONAL KNOCKOUT | BRAIN-DEVELOPMENT | NEUROSCIENCES | OLIGODENDROCYTE DIFFERENTIATION | CORPUS-CALLOSUM | IN-VIVO | POSTNATAL-DEVELOPMENT | Oligodendroglia - metabolism | Protein-Serine-Threonine Kinases - deficiency | Demyelinating Diseases - genetics | Cerebral Cortex - pathology | Gene Expression Regulation, Developmental - genetics | SOXF Transcription Factors - metabolism | Glial Fibrillary Acidic Protein - metabolism | Oligodendroglia - ultrastructure | Myelin Sheath - metabolism | Oligodendrocyte Transcription Factor 2 - metabolism | HMGB Proteins - genetics | HMGB Proteins - metabolism | Microfilament Proteins - metabolism | Demyelinating Diseases - pathology | Oligodendrocyte Transcription Factor 2 - genetics | Disease Models, Animal | Animals, Newborn | Calcium-Binding Proteins - metabolism | Microscopy, Electron, Transmission | Myelin Sheath - pathology | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Transcription Factors - genetics | Mutation - genetics | Myelin Proteins - genetics | Astrocytes - ultrastructure | Transcription Factors - metabolism | Animals | Mice | Myelin Proteins - metabolism | SOXF Transcription Factors - genetics | Astrocytes - metabolism | Genetic transcription | DNA binding proteins | RNA | Analysis | Brain | Regulators | Transcription factors | Oligodendrocyte-myelin glycoprotein | Mental disorders | Myelin | Genes | Olig2 protein | Inflammation | Neurodevelopmental disorders | Kinases | Nkx2.2 protein | Gene expression | Sox10 protein | Myelin-associated glycoprotein | Glial stem cells | Mutants | Fibers | Axons | Myelination | Myelin proteolipid protein | Oligodendrocytes | Cells (biology)
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2005, Volume 8, Issue 7, pp. 865 - 872
Adult neurogenesis in mammals is restricted to two small regions, including the olfactory bulb, where GABAergic and dopaminergic interneurons are newly... 
MIGRATION | NEURAL STEM-CELLS | PROGENITORS | MAMMALIAN BRAIN | NEWLY GENERATED NEURONS | MOUSE FOREBRAIN | PAX6 | SUBVENTRICULAR ZONE | SPECIFICATION | OLIG2 | NEUROSCIENCES | Homeodomain Proteins - metabolism | Male | Neurons - cytology | Olfactory Bulb - metabolism | Stem Cells - cytology | Repressor Proteins - physiology | Tissue Distribution | Olfactory Bulb - growth & development | Cell Line - physiology | Ependyma - cytology | Neurons - physiology | Oligodendroglia - cytology | Dopamine - metabolism | Repressor Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors | Olfactory Bulb - cytology | Animals, Newborn | Nerve Tissue Proteins - physiology | Paired Box Transcription Factors | Mice, Inbred C57BL | Ependyma - metabolism | Oligodendrocyte Transcription Factor 2 | PAX6 Transcription Factor | Cell Division - physiology | Nerve Tissue Proteins - metabolism | Phenotype | Animals | Eye Proteins - metabolism | Ependyma - growth & development | Eye Proteins - physiology | Mice | Homeodomain Proteins - physiology | Cellular therapy | Transplantation immunology | Olfactory bulb | Neural transmission | Regulation | Research | Health aspects | Index Medicus | Cell Line | Dopamine | Neurons | Repressor Proteins | Neurons and Cognition | Neurobiology | Nerve Tissue Proteins | Olfactory Bulb | Stem Cells | Life Sciences | Homeodomain Proteins | Cell Division | Oligodendroglia | Ependyma | Eye Proteins
Journal Article
Glia, ISSN 0894-1491, 12/2017, Volume 65, Issue 12, pp. 2070 - 2086
Oligodendrocytes are essential regulators of axonal energy homeostasis and electrical conduction and emerging target cells for restoration of neurological... 
myelination | development | oligodendrocyte | remyelination | NERVOUS-SYSTEM | NEUROSCIENCES | OLIGODENDROCYTE DIFFERENTIATION | MULTIPLE-SCLEROSIS | AXONAL INTEGRITY | ERK1/2 MAPK | SPINAL-CORD-INJURY | SERINE-PROTEASE | THROMBIN RECEPTOR | BRAIN | Oligodendroglia - metabolism | MAP Kinase Signaling System - physiology | Nogo Proteins - genetics | Spinal Cord - growth & development | Receptor, PAR-2 - metabolism | Gene Expression Regulation, Developmental - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Stem Cells - metabolism | Spinal Cord Injuries - pathology | Myelin Basic Protein - genetics | Brain-Derived Neurotrophic Factor - pharmacology | Myelin Proteolipid Protein - metabolism | Spinal Cord - cytology | Cyclic AMP - metabolism | Receptor, PAR-2 - genetics | Animals, Newborn | Myelin Sheath - physiology | Myelin Basic Protein - metabolism | Spinal Cord Injuries - metabolism | Gene Expression Regulation, Developmental - drug effects | Mice, Transgenic | Animals | Nogo Proteins - metabolism | Myelin Proteolipid Protein - genetics | Stem Cells - drug effects | Mice | Spinal Cord Injuries - physiopathology | Multiple sclerosis | Proteases | Analysis | Cyclic adenylic acid | G proteins | Adenylic acid | Myelin proteins | Brain | Conduction | Regulators | Spinal cord | Proteinase | Olig2 protein | Homeostasis | Spinal cord injury | Myelin basic protein | Proteins | Adenylate cyclase | Nerve conduction | Clonal deletion | Restoration | Sheaths | Myelin proteolipid protein | Demyelination | Protease | Rodents | Oligodendrocytes | Deletion | Repair | Adenosine monophosphate | AMP | Myelin | Extracellular signal-regulated kinase | Cyclic AMP | Cultures | Electrical conduction | Resilience | Energy balance | Regeneration | Brain-derived neurotrophic factor | Proteolipid protein | Axon guidance | Index Medicus
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 03/2017, Volume 525, Issue 4, pp. 955 - 975
P11 (S100a10), a member of the S100 family of proteins, has widespread distribution in the vertebrate body, including in the brain, where it has a key role in... 
ependymal cells | anti‐GFP antibody RRID: AB_10073917 | endothelial cells | anti‐NeuN antibody RRID: AB_2298772 | anti‐p11 antibody RRID: AB_2183469 | anti‐Olig2 antibody RRID: AB_10861310 | anti‐GFP antibody RRID: AB_303395 | region‐specificity | neurons | glia | anti‐GFAP antibody RRID: AB_305808 | p11 | anti‐Aldh1L1 antibody RRID: AB_10712968 | anti‐CNPase antibody RRID: AB_10122287 | anti‐NG2 antibody RRID: AB_177646 | anti‐GFP antibody RRID: AB_10000240 | anti‐Iba1 antibody RRID: AB_839504 | expression mapping | depression | anti‐GFP antibody RRID: AB_300798 | meninges | anti-CNPase antibody RRID: AB_10122287 | anti-NeuN antibody RRID: AB_2298772 | region-specificity | anti-GFP antibody RRID: AB_300798 | anti-Aldh1L1 antibody RRID: AB_10712968 | anti-GFAP antibody RRID: AB_305808 | anti-GFP antibody RRID: AB_10073917 | anti-GFP antibody RRID: AB_303395 | anti-Olig2 antibody RRID: AB_10861310 | anti-Iba1 antibody RRID: AB_839504 | anti-p11 antibody RRID: AB_2183469 | anti-GFP antibody RRID: AB_10000240 | anti-NG2 antibody RRID: AB_177646 | ZOOLOGY | MEMBRANE DYNAMICS | NERVOUS-SYSTEM | WHITE-MATTER | MAJOR DEPRESSION | NEUROSCIENCES | PREFRONTAL CORTEX | CEREBRAL-CORTEX | TRANSLATIONAL PROFILING APPROACH | MOOD DISORDERS | BLOOD-VESSELS | GROWTH-FACTOR | Immunohistochemistry | Mice, Inbred C57BL | Male | Annexin A2 - biosynthesis | Mice, Knockout | Brain - metabolism | Depression - metabolism | Animals | In Situ Hybridization | Image Processing, Computer-Assisted | Female | Mice | S100 Proteins - biosynthesis | Proteins | Viral antibodies | Brain | Neurons | Antidepressants | Depression, Mental | Antibodies | Index Medicus
Journal Article
Stroke, ISSN 0039-2499, 12/2010, Volume 41, Issue 12, pp. 2944 - 2949
Background and Purpose-Although in vitro studies suggest that non-neurogenic regions of the adult central nervous system potentially contain multipotent... 
neurogenesis | NG2 | regeneration | stroke | ischemia | CHANNEL EXPRESSION | PROGENITOR CELLS | DISTINCT PHYSIOLOGICAL-PROPERTIES | TRANSCRIPTION FACTOR OLIG2 | STEM-CELLS | WHITE-MATTER | SPINAL-CORD | SUBVENTRICULAR ZONE | CLINICAL NEUROLOGY | ADULT OLFACTORY-BULB | PERIPHERAL VASCULAR DISEASE | Paired Box Transcription Factors - biosynthesis | Paired Box Transcription Factors - genetics | Glial Fibrillary Acidic Protein - genetics | Microtubule-Associated Proteins - genetics | Gene Expression - genetics | Green Fluorescent Proteins - genetics | Sodium Channels - physiology | Corpus Striatum - metabolism | Repressor Proteins - physiology | Retroviridae - genetics | Gene Expression - physiology | Neuropeptides - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Nerve Tissue Proteins - biosynthesis | Neurons - physiology | Eye Proteins - genetics | Neuropeptides - genetics | Ischemic Attack, Transient - metabolism | Ischemic Attack, Transient - physiopathology | Basic Helix-Loop-Helix Transcription Factors - genetics | Homeodomain Proteins - biosynthesis | Neural Stem Cells - physiology | Paired Box Transcription Factors - physiology | Repressor Proteins - genetics | Oligodendrocyte Transcription Factor 2 | PAX6 Transcription Factor | Membrane Potentials - physiology | Microtubule-Associated Proteins - biosynthesis | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Glial Fibrillary Acidic Protein - biosynthesis | Patch-Clamp Techniques | Phenotype | Animals | Repressor Proteins - biosynthesis | Image Processing, Computer-Assisted | Corpus Striatum - physiology | Neuroglia - metabolism | Eye Proteins - physiology | Mice | Electrophysiological Phenomena | Homeodomain Proteins - physiology | Eye Proteins - biosynthesis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, pp. e22018 - e22018
Background: Neurons and astrocytes are generated from common neural precursors, yet neurogenesis precedes astrocyte formation during embryogenesis. The... 
CARCINOMA-CELLS | OLIGODENDROCYTE DIFFERENTIATION | HUMAN GENOME | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | ASTROCYTE DIFFERENTIATION | GENE-EXPRESSION | TRANSCRIPTIONAL REPRESSION | ACTIVE GENES | HISTONE DEACETYLASE | Immunohistochemistry | Cell Cycle - genetics | Chromatin - metabolism | Glial Fibrillary Acidic Protein - genetics | Immunoprecipitation | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Protein Transport - physiology | Glial Fibrillary Acidic Protein - metabolism | Cell Differentiation - genetics | Cell Nucleus - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chromatin Immunoprecipitation | RNA Interference | Lentivirus - genetics | DNA Methylation - physiology | Cell Differentiation - physiology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Cell Line | DNA Methylation - genetics | Oligodendrocyte Transcription Factor 2 | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Protein Transport - genetics | Nerve Tissue Proteins - metabolism | Animals | Cell Cycle - physiology | Protein Binding | Mice | Epigenetic inheritance | Embryonic development | Chromatin | RNA | Genes | Genetic transcription | Cell differentiation | Genomics | Differentiation (biology) | Olig2 protein | Event-related potentials | Kinases | Neurogenesis | DNA-directed RNA polymerase | Recruitment | Embryogenesis | Methyl-CpG binding protein | Cell fate | Coding | Rodents | DNA methylation | Acetylation | Astrocytes | Glial fibrillary acidic protein | Stat3 protein | Gene expression | Chromatin remodeling | Embryonic growth stage | Polymerase | Gene silencing | Ribonucleic acids | MeCP2 protein | Neural stem cells | Methylation | RNA polymerase II | Cytoplasm | Index Medicus
Journal Article
STEM CELLS, ISSN 1066-5099, 03/2017, Volume 35, Issue 3, pp. 754 - 765
The prion protein is infamous for its involvement in a group of neurodegenerative diseases known as Transmissible Spongiform Encephalopathies. In the... 
Neural stem cells | Cadherins | Prion protein | Epidermal growth factor receptor | Notch | PROGENITOR CELLS | NERVOUS-SYSTEM | BRAIN-DEVELOPMENT | NICHE | SELF-RENEWAL | PROLIFERATION | EGFR | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HEMATOPOIETIC STEM-CELLS | GENE-EXPRESSION | DIFFERENTIATION | HEMATOLOGY | Biomarkers - metabolism | Cell Line | Cadherins - metabolism | Signal Transduction | Receptors, Notch - metabolism | Cell Communication | Embryonic Development | Prion Proteins - metabolism | Embryo, Mammalian - metabolism | Cell Lineage | Feedback, Physiological | Receptor, Epidermal Growth Factor - metabolism | Animals | Mice | Neural Stem Cells - metabolism | Embryonic development | Nervous system diseases | Epidermal growth factor | Analysis | Prions | Physiological aspects | Hematopoietic stem cells | Animal models | Nestin | Transcription | Genes | Olig2 protein | Stem cell transplantation | Control systems | Biology | Defects | Signal transduction | Receptors | Alterations | Negative feedback | N-Cadherin | Neural tube | Feedback | Neurospheres | Physiology | Neurodegenerative diseases | Epidermal growth factor receptors | Transmissible spongiform encephalopathy | Maintenance | Cadherin | Embryos | Diseases | Neurological diseases | Play | Molecular modelling | Depletion | Stem cells | Cells (biology) | Ligands | Notch protein | In vitro methods and tests | Index Medicus
Journal Article
Development, ISSN 0950-1991, 07/2001, Volume 128, Issue 13, pp. 2545 - 2554
In the caudal neural tube, oligodendrocyte progenitors (OLPs) originate in the ventral neuroepithelium under the influence of Sonic hedgehog (SHH), then... 
Telencephalon | Mouse | Oligodendrocyte | Rat | Hedgehog signalling | PROGENITOR CELLS | PDGF ALPHA-RECEPTOR | OPTIC-NERVE | rat | SONIC HEDGEHOG | oligodendrocyte | NEURAL-TUBE | telencephalon | MONOCLONAL-ANTIBODY | DEVELOPMENTAL BIOLOGY | SUBVENTRICULAR ZONE | mouse | hedgehog signalling | SPINAL-CORD OLIGODENDROCYTES | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | Cerebral Cortex - pathology | Receptors, Cell Surface | Stem Cells - cytology | Genes, Overlapping | Cerebral Cortex - metabolism | Hedgehog Proteins | SOXE Transcription Factors | Cell Differentiation | Oligodendroglia - cytology | Patched Receptors | Prosencephalon - metabolism | Basic Helix-Loop-Helix Transcription Factors | Prosencephalon - pathology | Gene Expression | Telencephalon - metabolism | Telencephalon - cytology | Membrane Proteins - genetics | Mice, Inbred C57BL | Trans-Activators | Cells, Cultured | Intracellular Signaling Peptides and Proteins | Rats | Oligodendrocyte Transcription Factor 2 | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | Mice, Knockout | Proteins - genetics | Cell Lineage | Animals | Proteins - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Mice | Transcription Factors | Patched-1 Receptor | High Mobility Group Proteins - genetics | OLIG2 protein | Sonic hedgehog protein | Nkx2.1 gene | Shh gene | Indian hedgehog protein | Sonic hedgehog gene | OLIG1 protein | Hedgehog gene | cyclopamine | Sox10 protein | Index Medicus
Journal Article
Human Pathology, ISSN 0046-8177, 09/2019, Volume 91, pp. 77 - 85
Alveolar rhabdomyosarcoma (RMS) is associated with an underlying pathogenic translocation involving either or and . The presence or absence of this fusion... 
Translocation | Immunohistochemistry | PAX7 | Rhabdomyosarcoma | PAX3 | OLIG2 | Gene expression
Journal Article