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Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 1, pp. 195 - 207
Th17 cells are potent mediators in autoimmune diseases, and RORγt is required for their development. Recent studies have shown that RORγt+ Treg cells in the... 
Tr17 | autoimmunity | Foxp3 | Treg | IL-17 | RORγt | REMITTING MULTIPLE-SCLEROSIS | ROR-GAMMA-T | INFLAMMATION | HELPER-CELLS | TRANSCRIPTION | CCR6 | DIFFERENTIATION | T-H-17 CELLS | SUPPRESSION | EXPRESSION | CELL BIOLOGY | Forkhead Transcription Factors - immunology | Receptors, CCR6 - immunology | Autoimmunity - genetics | Encephalomyelitis, Autoimmune, Experimental - immunology | Myelin-Oligodendrocyte Glycoprotein - administration & dosage | Green Fluorescent Proteins - genetics | Adoptive Transfer | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Inducible T-Cell Co-Stimulator Protein - genetics | Cell Differentiation | Encephalomyelitis, Autoimmune, Experimental - genetics | Genes, Reporter | Inducible T-Cell Co-Stimulator Protein - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | STAT3 Transcription Factor - genetics | Th17 Cells - pathology | Green Fluorescent Proteins - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Encephalomyelitis, Autoimmune, Experimental - pathology | Interleukin-6 - genetics | Signal Transduction | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Gene Expression Regulation | Mice, Transgenic | Forkhead Transcription Factors - genetics | Animals | Interleukin-6 - immunology | Receptors, CCR6 - genetics | Th17 Cells - immunology | Mice | Mice, Inbred BALB C | T-Lymphocytes, Regulatory - transplantation | STAT3 Transcription Factor - immunology
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 56, pp. 78 - 85
Abstract Multiple sclerosis (MS) is a progressive demyelinating disease of the central nervous system (CNS). Many nerve axons are insulated by a myelin sheath... 
Advanced Basic Science | Dentistry | Multiple sclerosis | Leukaemia inhibitory factor | Myelin | Nanotherapy | Remyelination | IMMUNE-MEDIATED DEMYELINATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MACROPHAGES | PROLIFERATION | MATURATION | ASTROCYTES | DELIVERY | MULTIPLE-SCLEROSIS | SECRETION | EXPRESSION | PLGA NANOPARTICLES | Gold - chemistry | Cytokines - metabolism | Nanoparticles - chemistry | Biocompatible Materials - chemistry | Mice, Inbred C57BL | Rats | Male | Axons - physiology | Chondroitin Sulfates - chemistry | Microscopy, Electron | Neural Stem Cells - cytology | Multiple Sclerosis - therapy | Proteoglycans - chemistry | Rats, Sprague-Dawley | Antigens - chemistry | Leukemia Inhibitory Factor - chemistry | Drug Delivery Systems | Animals | Cell Differentiation | Mice | Lysophosphatidylcholines - chemistry | Myelin Sheath - chemistry | Oligodendroglia - cytology | Nanoparticles | Analysis | Leukemia | Therapeutics | Sulfates | Biomedical engineering | Homeopathy | Materia medica and therapeutics | Surgical implants | Axons | Biomedical materials | Drug delivery systems | Process control | Mathematical models | Repair | OPC, oligodendrocyte precursor cell | NP, nanoparticle | PBS, phosphate buffered saline | OD, oligodendrocyte | MS, multiple sclerosis | EM, electron microscopy | CNS, central nervous system | LIF, leukaemia inhibitory factor | PFA, paraformaldehyde | dpl, days post lesion
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3887 - 20
Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system, and have the capacity to regenerate oligodendrocytes and myelin.... 
PROGENITOR CELLS | PATHOGENESIS | MULTIPLE-SCLEROSIS LESIONS | AUTOIMMUNE | INTERFERON-GAMMA | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | REMYELINATION | CENTRAL-NERVOUS-SYSTEM | CD8(+) T-CELLS | CYTOKINE GM-CSF | Caspase 7 - metabolism | Oligodendroglia - metabolism | Central Nervous System - metabolism | Humans | Caspase 3 - metabolism | Histocompatibility Antigens Class I | Central Nervous System - immunology | Myelin Sheath - metabolism | CD8-Positive T-Lymphocytes | Ovalbumin - metabolism | Remyelination - immunology | Oligodendrocyte Precursor Cells - drug effects | Demyelinating Diseases - immunology | CD4-Positive T-Lymphocytes | Cell Differentiation | Demyelinating Diseases - pathology | Cytokines - genetics | Oligodendrocyte Precursor Cells - metabolism | Disease Models, Animal | Interferon-gamma | Gene Expression | Cytokines - metabolism | T-Lymphocytes | Mice, Inbred C57BL | Oligodendrocyte Precursor Cells - pathology | Mice, Transgenic | Antigen-Presenting Cells - immunology | Animals | Oligodendrocyte Precursor Cells - immunology | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Antigens - immunology | Mice | Astrocytes - metabolism | Brain | Multiple sclerosis | CD8 antigen | Central nervous system | Effector cells | Cytotoxicity | Lymphocytes T | Glial stem cells | Inflammatory diseases | Demyelination | Lymphocytes | Precursors | Oligodendrocytes | Inhibition | Lesions | Immune system | Antigens | Myelin | Astrocytes | Substantia alba | Myelination | Major histocompatibility complex | Cell death | γ-Interferon | In vivo methods and tests
Journal Article
Glia, ISSN 0894-1491, 12/2017, Volume 65, Issue 12, pp. 2087 - 2098
The regeneration of oligodendrocytes is a crucial step in recovery from demyelination, as surviving oligodendrocytes exhibit limited structural plasticity and... 
oligodendrocyte progenitor cells | demyelination | multiple sclerosis | gray matter | remyelination | PROGENITOR CELLS | MULTIPLE-SCLEROSIS LESIONS | STEM-CELLS | WHITE-MATTER | CNS | NEUROSCIENCES | GLIA GENERATE | AXONAL LOSS | CORPUS-CALLOSUM | GRAY-MATTER | Age Factors | RNA, Untranslated - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Hippocampus - drug effects | Cell Lineage - drug effects | RNA, Untranslated - genetics | Cell Differentiation - genetics | Oligodendrocyte Precursor Cells - drug effects | Demyelinating Diseases - chemically induced | Demyelinating Diseases - pathology | Cell Lineage - genetics | Disease Models, Animal | Cuprizone - toxicity | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Mice, Inbred C57BL | Bacterial Proteins - genetics | Corpus Callosum - drug effects | Mice, Transgenic | Hippocampus - pathology | Monoamine Oxidase Inhibitors - toxicity | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Corpus Callosum - pathology | Remyelination - physiology | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Remyelination - drug effects | Luminescent Proteins - metabolism | Medicine, Experimental | Medical research | Multiple sclerosis | Platelet-derived growth factor | Cortex (cingulate) | Myelin | Central nervous system | Substantia alba | Substantia grisea | Plasticity (axonal) | Glial stem cells | Corpus callosum | Atrophy | Regeneration | Myelination | Cuprizone | Sheaths | Demyelination | Oligodendrocytes | Cells (biology) | In vivo methods and tests | Differentiation | Cortex (temporal)
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37589
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e39715
Homogeneous culture of neural precursor cells (NPCs) derived from human pluripotent stem cells (hPSCs) would provide a powerful tool for biomedical... 
DOPAMINE NEURONS | LINEAGE SELECTION | LONG-TERM PROLIFERATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | DIFFERENTIATION | EXPRESSION | POLYSIALIC ACID | PLASTICITY | Brain - cytology | Cell Proliferation | Cell Survival | Humans | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Sialic Acids - metabolism | Rats | Neurons - cytology | Neural Stem Cells - cytology | Rats, Sprague-Dawley | Stem Cell Transplantation | Animals | Immunomagnetic Separation | Neural Cell Adhesion Molecules - metabolism | Neural Stem Cells - transplantation | Female | Cell Differentiation | Neurons - metabolism | Cell Culture Techniques | Induced Pluripotent Stem Cells - cytology | Neural Stem Cells - metabolism | Induced Pluripotent Stem Cells - metabolism | Intermediate filament proteins | Nervous system diseases | Cell culture | Nestin | Spinal cord | Physicians | Stem cell transplantation | Nervous system | Drug screening | Cell surface | Cell adhesion molecules | Biomedical materials | Epidermal growth factor | Adhesive strength | Allografts | Precursors | Oligodendrocytes | Neostriatum | Cell adhesion | Physiology | Tumorigenesis | Telomerase | Cues | Neural cell adhesion molecule | Musashi protein | Neurodegenerative diseases | Cultivation | Neurons | Astrocytes | Polysialic acid | Gene expression | Neural crest | Embryos | Contamination | Medicine | Studies | Brain research | Grafts | Stem cells | Biomarkers | Neural stem cells | Surface markers | Pluripotency
Journal Article
Journal Article
Glia, ISSN 0894-1491, 08/2007, Volume 55, Issue 10, pp. 1001 - 1010
Journal Article