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1.
Full Text
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
Nature (London), ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 216 - 220
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oligodendroglia - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Cerebellum - drug effects | Myelin Sheath - drug effects | Male | Receptors, Glucocorticoid - metabolism | Demyelinating Diseases - metabolism | MAP Kinase Signaling System | Myelin Sheath - metabolism | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Germ Layers - drug effects | Germ Layers - pathology | Encephalomyelitis, Autoimmune, Experimental - pathology | Lysophosphatidylcholines | Pluripotent Stem Cells - cytology | Germ Layers - metabolism | Tissue Culture Techniques | Cerebellum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Cerebellum - pathology | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Miconazole - pharmacology | Pluripotent Stem Cells - drug effects | Multiple Sclerosis - pathology | Mice | Clobetasol - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Multiple Sclerosis - drug therapy | Medical research | Myelination | Multiple sclerosis | Stem cells | Physiological aspects | Medicine, Experimental | Research | Drugs | Proteins | Blood-brain barrier | Laboratories | Rodents | Clinical trials | FDA approval | Gene expression | Index Medicus
Journal Article
Nature (London), ISSN 0028-0836, 2014, Volume 506, Issue 7487, pp. 230 - 234
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Epidermal Growth Factor - administration & dosage | Oligodendroglia - metabolism | Receptor, Epidermal Growth Factor - genetics | Demyelinating Diseases - congenital | Brain Injuries - drug therapy | Humans | Brain Injuries - congenital | Male | Stem Cells - cytology | Demyelinating Diseases - metabolism | Epidermal Growth Factor - therapeutic use | Molecular Targeted Therapy | Stem Cells - metabolism | Cell Lineage - drug effects | Hypoxia - metabolism | Receptor, Epidermal Growth Factor - metabolism | Oligodendroglia - drug effects | Time Factors | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Disease Models, Animal | Animals, Newborn | Cell Survival - drug effects | Demyelinating Diseases - prevention & control | Administration, Intranasal | Infant, Premature, Diseases - drug therapy | Cell Division - drug effects | Brain Injuries - prevention & control | Oligodendroglia - pathology | Hypoxia - genetics | Regeneration - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Hypoxia - pathology | Stem Cells - drug effects | Hypoxia - physiopathology | Infant, Premature, Diseases - metabolism | Mice | Epidermal Growth Factor - pharmacology | Brain Injuries - pathology | Infant, Premature, Diseases - pathology | Brain | Medical research | Care and treatment | Infants (Premature) | Risk factors | Complications and side effects | Epidermal growth factor | Physiological aspects | Medicine, Experimental | Hypoxia | Diagnosis | Health aspects | Injuries | Brain damage | Attention Deficit Hyperactivity Disorder | Rodents | Apoptosis | Index Medicus
Journal Article
Annals of neurology, ISSN 0364-5134, 01/2008, Volume 63, Issue 1, pp. 61 - 71
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Lysophospholipids - metabolism | Oligodendroglia - metabolism | Extracellular Signal-Regulated MAP Kinases - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Cell Movement - physiology | rho-Associated Kinases - antagonists & inhibitors | Oligodendroglia - drug effects | rho-Associated Kinases - metabolism | Propylene Glycols - therapeutic use | Receptors, Lysosphingolipid - genetics | Sphingosine - metabolism | Receptors, G-Protein-Coupled - drug effects | Receptors, Lysosphingolipid - metabolism | Cell Differentiation - physiology | Immunosuppressive Agents - pharmacology | Cell Survival - physiology | Suramin - pharmacology | RNA, Messenger - drug effects | Propylene Glycols - pharmacology | Cell Line | Cell Survival - drug effects | Fingolimod Hydrochloride | Down-Regulation - drug effects | Down-Regulation - genetics | Sphingosine - pharmacology | Cell Movement - drug effects | Sphingosine - analogs & derivatives | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Surface Extensions - drug effects | Cytoskeleton - metabolism | Receptors, Lysosphingolipid - agonists | Stem Cells - drug effects | Signal Transduction - physiology | Sphingosine - therapeutic use | Cytoskeleton - drug effects | Index Medicus
Journal Article
Stroke (1970), ISSN 0039-2499, 01/2015, Volume 46, Issue 1, pp. 221 - 228
endothelin-1 | subcortical stroke | brain-derived neurotrophic factor | Clinical Neurology | Peripheral Vascular Disease | Neurosciences & Neurology | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Brain Ischemia - complications | Myelin Sheath - physiology | Myelin Sheath - pathology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - drug effects | Myelin Sheath - drug effects | Rats | White Matter - drug effects | Adenomatous Polyposis Coli Protein - drug effects | Diffusion Tensor Imaging | White Matter - pathology | Brain - drug effects | Stroke - pathology | Magnetic Resonance Imaging | Receptor, Platelet-Derived Growth Factor alpha - drug effects | Brain-Derived Neurotrophic Factor - pharmacology | Stroke - etiology | Animals | Oligodendroglia - drug effects | Cell Differentiation - drug effects | Brain Ischemia - pathology | Brain - pathology | Myelin Basic Protein - drug effects | Basic Helix-Loop-Helix Transcription Factors - drug effects | Index Medicus
Journal Article
Nature (London), ISSN 0028-0836, 2013, Volume 502, Issue 7471, pp. 327 - 332
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cuprizone - therapeutic use | Oligodendroglia - metabolism | Optic Nerve - cytology | Recurrence | Antiparkinson Agents - pharmacology | Coculture Techniques | Myelin Sheath - drug effects | Receptor, Muscarinic M1 - antagonists & inhibitors | Stem Cells - cytology | Myelin Proteolipid Protein - pharmacology | Myelin Sheath - metabolism | Antiparkinson Agents - therapeutic use | Oligodendroglia - drug effects | Cuprizone - pharmacology | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Propylene Glycols - therapeutic use | Immune System - immunology | Female | Oligodendroglia - cytology | Benztropine - therapeutic use | Propylene Glycols - pharmacology | Encephalomyelitis, Autoimmune, Experimental - pathology | Myelin Sheath - pathology | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Receptor, Muscarinic M3 - metabolism | Fingolimod Hydrochloride | Rats | Receptor, Muscarinic M3 - antagonists & inhibitors | Oligodendroglia - pathology | Sphingosine - pharmacology | Regeneration - drug effects | Sphingosine - analogs & derivatives | Animals | Cell Differentiation - drug effects | Models, Biological | Immune System - drug effects | Multiple Sclerosis - pathology | Stem Cells - drug effects | Sphingosine - therapeutic use | Mice | Benztropine - pharmacology | Receptor, Muscarinic M1 - metabolism | Multiple Sclerosis - drug therapy | Benztropine | Multiple sclerosis | Myelination | Physiological aspects | Oligodendroglia | Dosage and administration | Drug therapy | Cell differentiation | Cell culture | Dopamine | Drug dosages | Rodents | Cell cycle | Index Medicus
Journal Article
6.
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Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic
Lancet neurology, ISSN 1474-4422, 2009, Volume 8, Issue 5, pp. 491 - 500
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuroprotective Agents - therapeutic use | Astrocytes - drug effects | Neovascularization, Physiologic - drug effects | Recovery of Function - drug effects | Humans | Axons - drug effects | Neuronal Plasticity - drug effects | Clinical Trials as Topic | Stroke - drug therapy | Stroke - physiopathology | Brain - drug effects | Brain - blood supply | Animals | Oligodendroglia - drug effects | Neurogenesis - drug effects | Stroke (Disease) | Care and treatment | Neurons | Injuries | Stem cells | Index Medicus
Journal Article
International journal of molecular sciences, ISSN 1661-6596, 10/2017, Volume 18, Issue 10, p. 2220
158N murine oligodendrocytes | Mitochondria | 7-ketocholesterol | Lysosome | Peroxisome | Argan oil | Oxiapoptophagy | Extra virgin olive oil | α-tocopherol | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Lysosomes - drug effects | Cell Line | Plant Oils - pharmacology | Apoptosis - drug effects | Antioxidants - pharmacology | Mitochondria - drug effects | Peroxisomes - drug effects | Animals | Neuroprotective Agents - pharmacology | Oligodendroglia - drug effects | Ketocholesterols - toxicity | Mice | Oxidative Stress - drug effects | Lipid Peroxidation | alpha-Tocopherol - pharmacology | Brain | Oxidative stress | Membrane permeability | Lipid peroxidation | Cytotoxicity | Palmitic acid | Antioxidants | Adhesive strength | Oligodendrocytes | Cell adhesion | Polyphenols | Oxidation | Heart diseases | Neurodegenerative diseases | Phytosterols | Olive oil | Fatty acids | Cholesterol | Tyrosol | Neurological diseases | Cell death | Tocopherols | Molecular biology | Tocopherol | Cardiovascular diseases | Phagocytosis | Apoptosis | Index Medicus | Antioxidants/pharmacology | Neurons and Cognition | Oligodendroglia/drug effects | alpha-Tocopherol/pharmacology | Apoptosis/drug effects | Neurobiology | Ketocholesterols/toxicity | Neuroprotective Agents/pharmacology | Chemical Sciences | Oxidative Stress/drug effects | Life Sciences | Medicinal Chemistry | Lysosomes/drug effects | Plant Oils/pharmacology | Peroxisomes/drug effects | Mitochondria/drug effects | Food engineering | oxiapoptophagy | mitochondria | peroxisome | extra virgin olive oil | lysosome | argan oil
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