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1. Full Text Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
by Najm, Fadi J and Madhavan, Mayur and Zaremba, Anita and Shick, Elizabeth and Karl, Robert T and Factor, Daniel C and Miller, Tyler E and Nevin, Zachary S and Kantor, Christopher and Sargent, Alex and Quick, Kevin L and Schlatzer, Daniela M and Tang, Hong and Papoian, Ruben and Brimacombe, Kyle R and Shen, Min and Boxer, Matthew B and Jadhav, Ajit and Robinson, Andrew P and Podojil, Joseph R and Miller, Stephen D and Miller, Robert H and Tesar, Paul J
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 216 - 220
Multiple sclerosis involves an aberrant autoimmune response and progressive failure of remyelination in the central nervous system. Prevention of neural... 
MYELIN BASIC-PROTEIN | TRANSCRIPTS | GLUCOCORTICOIDS | MULTIPLE-SCLEROSIS | LYSOLECITHIN | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | OLIGODENDROCYTE PROGENITOR CELLS | Oligodendroglia - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Cerebellum - drug effects | Myelin Sheath - drug effects | Male | Receptors, Glucocorticoid - metabolism | Demyelinating Diseases - metabolism | MAP Kinase Signaling System | Myelin Sheath - metabolism | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Germ Layers - drug effects | Germ Layers - pathology | Encephalomyelitis, Autoimmune, Experimental - pathology | Lysophosphatidylcholines | Pluripotent Stem Cells - cytology | Germ Layers - metabolism | Tissue Culture Techniques | Cerebellum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Cerebellum - pathology | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Miconazole - pharmacology | Pluripotent Stem Cells - drug effects | Multiple Sclerosis - pathology | Mice | Clobetasol - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Multiple Sclerosis - drug therapy | Medical research | Myelination | Multiple sclerosis | Stem cells | Physiological aspects | Medicine, Experimental | Research | Drugs | Proteins | Blood-brain barrier | Laboratories | Rodents | Clinical trials | FDA approval | Gene expression | Index Medicus
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2. Full Text A regenerative approach to the treatment of multiple sclerosis
by Deshmukh, Vishal A and Tardif, Virginie and Lyssiotis, Costas A and Green, Chelsea C and Kerman, Bilal and Kim, Hyung Joon and Padmanabhan, Krishnan and Swoboda, Jonathan G and Ahmad, Insha and Kondo, Toru and Gage, Fred H and Theofilopoulos, Argyrios N and Lawson, Brian R and Schultz, Peter G and Lairson, Luke L
Nature, ISSN 0028-0836, 2013, Volume 502, Issue 7471, pp. 327 - 332
Progressive phases of multiple sclerosis are associated with inhibited differentiation of the progenitor cell population that generates the mature... 
OLIGODENDROCYTE DIFFERENTIATION | PROGENITOR CELLS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MUSCARINIC RECEPTOR SUBTYPES | THYROID-HORMONE | MYELIN REPAIR | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | PRECURSOR CELLS | Cuprizone - therapeutic use | Oligodendroglia - metabolism | Optic Nerve - cytology | Recurrence | Antiparkinson Agents - pharmacology | Coculture Techniques | Myelin Sheath - drug effects | Receptor, Muscarinic M1 - antagonists & inhibitors | Stem Cells - cytology | Myelin Proteolipid Protein - pharmacology | Myelin Sheath - metabolism | Antiparkinson Agents - therapeutic use | Oligodendroglia - drug effects | Cuprizone - pharmacology | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Propylene Glycols - therapeutic use | Immune System - immunology | Female | Oligodendroglia - cytology | Benztropine - therapeutic use | Propylene Glycols - pharmacology | Encephalomyelitis, Autoimmune, Experimental - pathology | Myelin Sheath - pathology | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Receptor, Muscarinic M3 - metabolism | Fingolimod Hydrochloride | Rats | Receptor, Muscarinic M3 - antagonists & inhibitors | Oligodendroglia - pathology | Sphingosine - pharmacology | Regeneration - drug effects | Sphingosine - analogs & derivatives | Animals | Cell Differentiation - drug effects | Models, Biological | Immune System - drug effects | Multiple Sclerosis - pathology | Stem Cells - drug effects | Sphingosine - therapeutic use | Mice | Benztropine - pharmacology | Receptor, Muscarinic M1 - metabolism | Multiple Sclerosis - drug therapy | Benztropine | Multiple sclerosis | Myelination | Physiological aspects | Oligodendroglia | Dosage and administration | Drug therapy | Cell differentiation | Cell culture | Dopamine | Drug dosages | Rodents | Cell cycle | Index Medicus
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3. Full Text Intranasal epidermal growth factor treatment rescues neonatal brain injury
by Scafidi, Joseph and Hammond, Timothy R and Scafidi, Susanna and Ritter, Jonathan and Jablonska, Beata and Roncal, Maria and Szigeti-Buck, Klara and Coman, Daniel and Huang, Yuegao and McCarter Jr, Robert J and Hyder, Fahmeed and Horvath, Tamas L and Gallo, Vittorio
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7487, pp. 230 - 234
There are no clinically relevant treatments available that improve function in the growing population of very preterm infants (less than 32 weeks' gestation)... 
MULTIPLE-SCLEROSIS | LOW-BIRTH-WEIGHT | OLIGODENDROCYTE PROGENITORS | MULTIDISCIPLINARY SCIENCES | HYPOXIC INJURY | CENTRAL-NERVOUS-SYSTEM | MOUSE CORPUS-CALLOSUM | PRETERM INFANTS | RAT-BRAIN | WHITE-MATTER ABNORMALITIES | FACTOR RECEPTOR | Epidermal Growth Factor - administration & dosage | Oligodendroglia - metabolism | Receptor, Epidermal Growth Factor - genetics | Demyelinating Diseases - congenital | Brain Injuries - drug therapy | Humans | Brain Injuries - congenital | Male | Stem Cells - cytology | Demyelinating Diseases - metabolism | Epidermal Growth Factor - therapeutic use | Molecular Targeted Therapy | Stem Cells - metabolism | Cell Lineage - drug effects | Hypoxia - metabolism | Receptor, Epidermal Growth Factor - metabolism | Oligodendroglia - drug effects | Time Factors | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Disease Models, Animal | Animals, Newborn | Cell Survival - drug effects | Demyelinating Diseases - prevention & control | Administration, Intranasal | Infant, Premature, Diseases - drug therapy | Cell Division - drug effects | Brain Injuries - prevention & control | Oligodendroglia - pathology | Hypoxia - genetics | Regeneration - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Hypoxia - pathology | Stem Cells - drug effects | Hypoxia - physiopathology | Infant, Premature, Diseases - metabolism | Mice | Epidermal Growth Factor - pharmacology | Brain Injuries - pathology | Infant, Premature, Diseases - pathology | Brain | Medical research | Care and treatment | Infants (Premature) | Risk factors | Complications and side effects | Epidermal growth factor | Physiological aspects | Medicine, Experimental | Hypoxia | Diagnosis | Health aspects | Injuries | Attention deficit disorder | Brain damage | Rodents | Apoptosis | Index Medicus
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4. Full Text Brain-Derived Neurotrophic Factor Administration Mediated Oligodendrocyte Differentiation and Myelin Formation in Subcortical Ischemic Stroke
by Ramos-Cejudo, Jaime and Gutiérrez-Fernández, María and Otero-Ortega, Laura and Rodríguez-Frutos, Berta and Fuentes, Blanca and Vallejo-Cremades, Maria Teresa and Hernanz, Teresa Navarro and Cerdán, Sebastián and Díez-Tejedor, Exuperio
Stroke, ISSN 0039-2499, 01/2015, Volume 46, Issue 1, pp. 221 - 228
BACKGROUND AND PURPOSE—Translational research is beginning to reveal the importance of trophic factors as a therapy for cellular brain repair. The purpose of... 
endothelin-1 | subcortical stroke | brain-derived neurotrophic factor | CELLS | RECOVERY | RAT | BDNF | WHITE-MATTER STROKE | PERIPHERAL VASCULAR DISEASE | CENTRAL-NERVOUS-SYSTEM | MICE | CLINICAL NEUROLOGY | Brain Ischemia - complications | Myelin Sheath - physiology | Myelin Sheath - pathology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - drug effects | Myelin Sheath - drug effects | Rats | White Matter - drug effects | Adenomatous Polyposis Coli Protein - drug effects | Diffusion Tensor Imaging | White Matter - pathology | Brain - drug effects | Stroke - pathology | Magnetic Resonance Imaging | Receptor, Platelet-Derived Growth Factor alpha - drug effects | Brain-Derived Neurotrophic Factor - pharmacology | Stroke - etiology | Animals | Oligodendroglia - drug effects | Cell Differentiation - drug effects | Brain Ischemia - pathology | Brain - pathology | Myelin Basic Protein - drug effects | Basic Helix-Loop-Helix Transcription Factors - drug effects | Index Medicus
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5. Full Text FTY720 modulates human oligodendrocyte progenitor process extension and survival
by Miron, Veronique E and Jung, Cha Gyun and Kim, Hye Jung and Kennedy, Timothy E and Soliven, Betty and Antel, Jack P
Annals of Neurology, ISSN 0364-5134, 01/2008, Volume 63, Issue 1, pp. 61 - 71
Objective: FTY720, a sphingosine-1-phosphate (S1P) receptor agonist that crosses the blood-brain barrier, is a potential immuno-therapy for multiple sclerosis.... 
SIGNAL-TRANSDUCTION | CELLS | 1-PHOSPHATE RECEPTOR AGONIST | MULTIPLE-SCLEROSIS | LYSOPHOSPHATIDIC ACID | PROCESS RETRACTION | SUBCORTICAL WHITE-MATTER | COUPLED RECEPTORS | G-PROTEIN | NEUROSCIENCES | CLINICAL NEUROLOGY | SPHINGOSINE 1-PHOSPHATE | Lysophospholipids - metabolism | Oligodendroglia - metabolism | Extracellular Signal-Regulated MAP Kinases - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Cell Movement - physiology | rho-Associated Kinases - antagonists & inhibitors | Oligodendroglia - drug effects | rho-Associated Kinases - metabolism | Propylene Glycols - therapeutic use | Receptors, Lysosphingolipid - genetics | Sphingosine - metabolism | Receptors, G-Protein-Coupled - drug effects | Receptors, Lysosphingolipid - metabolism | Cell Differentiation - physiology | Immunosuppressive Agents - pharmacology | Cell Survival - physiology | Suramin - pharmacology | RNA, Messenger - drug effects | Propylene Glycols - pharmacology | Cell Line | Cell Survival - drug effects | Fingolimod Hydrochloride | Down-Regulation - drug effects | Down-Regulation - genetics | Sphingosine - pharmacology | Cell Movement - drug effects | Sphingosine - analogs & derivatives | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Surface Extensions - drug effects | Cytoskeleton - metabolism | Receptors, Lysosphingolipid - agonists | Stem Cells - drug effects | Signal Transduction - physiology | Sphingosine - therapeutic use | Cytoskeleton - drug effects | Index Medicus
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6. Full Text Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination
by Fancy, Stephen P. J and Harrington, Emily P and Yuen, Tracy J and Silbereis, John C and Zhao, Chao and Baranzini, Sergio E and Bruce, Charlotte C and Otero, Jose J and Huang, Eric J and Nusse, Roel and Franklin, Robin J. M and Rowitch, David H
Nature Neuroscience, ISSN 1097-6256, 08/2011, Volume 14, Issue 8, pp. 1009 - 1016
Permanent damage to white matter tracts, comprising axons and myelinating oligodendrocytes, is an important component of brain injuries of the newborn that... 
FUNCTIONAL INTERACTION | MULTIPLE-SCLEROSIS | CNS REMYELINATION | MYELINATION | SIGNALING PATHWAY | TRANSCRIPTION | DIFFERENTIATION | BETA-CATENIN | NEUROSCIENCES | WHITE-MATTER INJURY | NEGATIVE REGULATOR | Humans | Ki-67 Antigen - metabolism | Male | Brain Injuries - metabolism | Wnt Proteins - metabolism | Oligodendroglia - drug effects | Hypoxia-Ischemia, Brain - therapy | Infant, Newborn | Organ Culture Techniques | Disease Models, Animal | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Mice, Transgenic | Oligodendrocyte Transcription Factor 2 | Brain Injuries - therapy | Multiple Sclerosis - therapy | Myelin Proteins - genetics | beta Catenin - metabolism | Heterocyclic Compounds, 3-Ring - therapeutic use | Spinal Cord - physiology | Axin Protein | Mice | Myelin Sheath - ultrastructure | beta-Galactosidase - genetics | Cerebellum - ultrastructure | Myelin Proteins - metabolism | Corpus Callosum - metabolism | Spinal Cord - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Myelin Proteins - therapeutic use | Cerebellum - drug effects | Myelin Sheath - drug effects | Hypoxia-Ischemia, Brain - pathology | Cerebral Cortex - cytology | Cytoskeletal Proteins - deficiency | Dose-Response Relationship, Drug | Oligodendroglia - physiology | Wnt Proteins - genetics | beta-Galactosidase - metabolism | Adult | Cytoskeletal Proteins - metabolism | Female | Demyelinating Diseases - chemically induced | Demyelinating Diseases - pathology | Neurons - drug effects | Cell Differentiation - physiology | Hypoxia-Ischemia, Brain - metabolism | Microscopy, Electron, Transmission | Myelin Sheath - pathology | Gene Expression Regulation - genetics | Cerebellum - metabolism | Cells, Cultured | Gene Expression Regulation - physiology | Corpus Callosum - drug effects | Nerve Tissue Proteins - genetics | beta Catenin - genetics | Multiple Sclerosis - complications | Nerve Tissue Proteins - metabolism | Animals | Cell Differentiation - drug effects | Multiple Sclerosis - pathology | Stem Cells - drug effects | Brain Injuries - etiology | Lysophosphatidylcholines - toxicity | Postmortem Changes | Infants (Newborn) | Brain | Care and treatment | Physiological aspects | Research | Binding proteins | Health aspects | Injuries | Index Medicus
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7. Full Text Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models
by Bai, Lianhua and Lennon, Donald P and Caplan, Arnold I and Dechant, Anne and Hecker, Jordan and Kranso, Janet and Zaremba, Anita and Miller, Robert H
Nature Neuroscience, ISSN 1097-6256, 06/2012, Volume 15, Issue 6, pp. 862 - 870
Mesenchymal stem cells (MSCs) have emerged as a potential therapy for a range of neural insults. In animal models of multiple sclerosis, an autoimmune disease... 
IMMUNE-RESPONSE | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | LIVER-REGENERATION | C-MET | BONE-MARROW | ENDOTHELIAL-CELLS | ENDOGENOUS REPAIR | SPINAL-CORD-INJURY | CENTRAL-NERVOUS-SYSTEM | MET TYROSINE KINASE | NEUROSCIENCES | Proto-Oncogene Proteins c-met - metabolism | Oligodendroglia - metabolism | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - metabolism | Recovery of Function - drug effects | Humans | Culture Media, Conditioned - pharmacology | Neurons - cytology | Stem Cells - cytology | Hepatocyte Growth Factor - pharmacology | Stem Cells - metabolism | Oligodendroglia - drug effects | Spinal Cord - pathology | Female | Neurogenesis - drug effects | Neurons - metabolism | Oligodendroglia - cytology | Neurons - drug effects | Multiple Sclerosis - metabolism | Encephalomyelitis, Autoimmune, Experimental - pathology | Mice, Inbred C57BL | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Rats | Multiple Sclerosis - therapy | Blotting, Western | Hepatocyte Growth Factor - metabolism | Encephalomyelitis, Autoimmune, Experimental - therapy | Animals | Cell Differentiation - drug effects | Multiple Sclerosis - pathology | Stem Cells - drug effects | Mice | Mesenchymal Stem Cell Transplantation | Physiological aspects | Development and progression | Multiple sclerosis | Research | Growth factors | Stem cells | Index Medicus
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8. Full Text Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication
by Frühbeis, Carsten and Fröhlich, Dominik and Kuo, Wen Ping and Amphornrat, Jesa and Thilemann, Sebastian and Saab, Aiman S and Kirchhoff, Frank and Möbius, Wiebke and Goebbels, Sandra and Nave, Klaus-Armin and Schneider, Anja and Simons, Mikael and Klugmann, Matthias and Trotter, Jacqueline and Krämer-Albers, Eva-Maria
PLoS Biology, ISSN 1544-9173, 07/2013, Volume 11, Issue 7, pp. e1001604 - e1001604
Reciprocal interactions between neurons and oligodendrocytes are not only crucial for myelination, but also for long-term survival of axons. Degeneration of... 
MAJOR MYELIN | NMDA RECEPTORS | GLUTAMATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | MICROVESICLES | DEATH | RELEASE | PROTEINS | GLIA | PRECURSOR CELLS | TROPHIC SUPPORT | Exosomes - drug effects | Cell Survival - drug effects | Glutamic Acid - pharmacology | Mice, Inbred C57BL | Male | Neurons - cytology | Animals | Oligodendroglia - drug effects | Signal Transduction - drug effects | Neurotransmitter Agents - pharmacology | Cell Communication - drug effects | Female | Mice | Oligodendroglia - cytology | Neurons - drug effects | Index Medicus | Proteins | Medical research | Enzymes | Brain research | Neurons | Communication
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9. Full Text Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo
by Mensch, Sigrid and Baraban, Marion and Almeida, Rafael and Czopka, Tim and Ausborn, Jessica and El Manira, Abdeljabbar and Lyons, David A
Nature Neuroscience, ISSN 1097-6256, 04/2015, Volume 18, Issue 5, pp. 628 - 630
The myelination of axons by oligodendrocytes markedly affects CNS function, but how this is regulated by neuronal activity in vivo is not known. We found that... 
SYSTEM | MORPHOGENESIS | ZEBRAFISH | RETICULOSPINAL NEURONS | BEHAVIOR | DYNAMICS | ELECTRICAL-ACTIVITY | GENERATION | MATURATION | NEUROSCIENCES | BRAIN | Embryo, Nonmammalian - cytology | Myelin Sheath - physiology | Synaptic Vesicles - secretion | Spinal Cord - drug effects | Cell Count | Myelin Sheath - drug effects | Tetanus Toxin - pharmacology | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Animals | Oligodendroglia - drug effects | Neurons - physiology | Oligodendroglia - cytology | Spinal Cord - cytology | Neurons - drug effects | Pentylenetetrazole - pharmacology | Chimera | GABA-A Receptor Antagonists - pharmacology | Axons | Neural transmission | Genetic aspects | Properties | Central nervous system | Index Medicus
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10. Full Text Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
by Mei, Feng and Mei, Feng and Fancy, Stephen P.J and Shen, Yun-An A and Niu, Jianqin and Zhao, Chao and Presley, Bryan and Miao, Edna and Lee, Seonok and Mayoral, Sonia R and Mayoral, Sonia R and Redmond, Stephanie A and Etxeberria, Ainhoa and Xiao, Lan and Franklin, Robin J.M and Green, Ari and Hauser, Stephen L and Chan, Jonah R
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 8, pp. 954 - 960
Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis.... 
PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | MYELINATION | ADULT SPINAL-CORD | BIOCHEMISTRY & MOLECULAR BIOLOGY | OLIGODENDROCYTE PRECURSOR CELLS | CNS DEMYELINATION | LESIONS | CELL BIOLOGY | ENGINEERED NANOFIBERS | REMYELINATION | SCHWANN-CELLS | DIFFERENTIATION | Drug Evaluation, Preclinical - methods | Muscarinic Antagonists - isolation & purification | Mice, Inbred C57BL | Nerve Fibers, Myelinated - drug effects | Cells, Cultured | Rats | Mice, Transgenic | Nanostructures | Rats, Sprague-Dawley | Regeneration - drug effects | Animals | Oligodendroglia - drug effects | Oligodendroglia - physiology | Cell Differentiation - drug effects | Histamine H1 Antagonists - pharmacology | Muscarinic Antagonists - pharmacology | Female | Mice | Oligodendroglia - cytology | Clemastine - pharmacology | High-Throughput Screening Assays - methods | Multiple Sclerosis - drug therapy | Multiple sclerosis | Care and treatment | Diagnosis | High-throughput screening (Biochemical assaying) | Analysis | Models | Medical screening | Arrays | Rodents | Index Medicus
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11. Full Text M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
by Miron, Veronique E and Boyd, Amanda and Zhao, Jing-Wei and Yuen, Tracy J and Ruckh, Julia M and Shadrach, Jennifer L and Van Wijngaarden, Peter and Wagers, Amy J and Williams, Anna and Franklin, Robin J.M and Ffrench-Constant, Charles
Nature Neuroscience, ISSN 1097-6256, 09/2013, Volume 16, Issue 9, pp. 1211 - 1218
The lack of therapies for progressive multiple sclerosis highlights the need to understand the regenerative process of remyelination that can follow CNS... 
PROGENITOR CELLS | ACTIVIN-A | REGENERATION | GENE-EXPRESSION | MONOCYTES | INJURY | GADOLINIUM CHLORIDE | IDENTIFICATION | NEUROSCIENCES | PROGRESSION | BETA | Clodronic Acid - pharmacology | Humans | Middle Aged | Central Nervous System - pathology | Culture Media, Conditioned - pharmacology | Male | Cell Differentiation - genetics | Microglia - physiology | Oligodendroglia - drug effects | Oligodendroglia - physiology | Aged, 80 and over | Adult | Female | Cadmium Chloride - pharmacology | Demyelinating Diseases - pathology | Cell Differentiation - physiology | Animals, Newborn | Macrophages - physiology | Mice, Inbred C57BL | Cells, Cultured | Rats | Mice, Transgenic | Regeneration - physiology | Rats, Sprague-Dawley | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Central Nervous System - drug effects | Aged | Mice | In Vitro Techniques | Myelin Proteins - metabolism | Physiological aspects | Multiple sclerosis | Myelination | Research | Regeneration (Biology) | Macrophages | Index Medicus
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