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1. Full Text Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
by Najm, Fadi J and Madhavan, Mayur and Zaremba, Anita and Shick, Elizabeth and Karl, Robert T and Factor, Daniel C and Miller, Tyler E and Nevin, Zachary S and Kantor, Christopher and Sargent, Alex and Quick, Kevin L and Schlatzer, Daniela M and Tang, Hong and Papoian, Ruben and Brimacombe, Kyle R and Shen, Min and Boxer, Matthew B and Jadhav, Ajit and Robinson, Andrew P and Podojil, Joseph R and Miller, Stephen D and Miller, Robert H and Tesar, Paul J
Nature (London), ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 216 - 220
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oligodendroglia - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Cerebellum - drug effects | Myelin Sheath - drug effects | Male | Receptors, Glucocorticoid - metabolism | Demyelinating Diseases - metabolism | MAP Kinase Signaling System | Myelin Sheath - metabolism | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Germ Layers - drug effects | Germ Layers - pathology | Encephalomyelitis, Autoimmune, Experimental - pathology | Lysophosphatidylcholines | Pluripotent Stem Cells - cytology | Germ Layers - metabolism | Tissue Culture Techniques | Cerebellum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Cerebellum - pathology | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Miconazole - pharmacology | Pluripotent Stem Cells - drug effects | Multiple Sclerosis - pathology | Mice | Clobetasol - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Multiple Sclerosis - drug therapy | Medical research | Myelination | Multiple sclerosis | Stem cells | Physiological aspects | Medicine, Experimental | Research | Drugs | Proteins | Blood-brain barrier | Laboratories | Rodents | Clinical trials | FDA approval | Gene expression | Index Medicus
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2. Full Text Intranasal epidermal growth factor treatment rescues neonatal brain injury
by Scafidi, Joseph and Hammond, Timothy R and Scafidi, Susanna and Ritter, Jonathan and Jablonska, Beata and Roncal, Maria and Szigeti-Buck, Klara and Coman, Daniel and Huang, Yuegao and McCarter Jr, Robert J and Hyder, Fahmeed and Horvath, Tamas L and Gallo, Vittorio
Nature (London), ISSN 0028-0836, 2014, Volume 506, Issue 7487, pp. 230 - 234
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Epidermal Growth Factor - administration & dosage | Oligodendroglia - metabolism | Receptor, Epidermal Growth Factor - genetics | Demyelinating Diseases - congenital | Brain Injuries - drug therapy | Humans | Brain Injuries - congenital | Male | Stem Cells - cytology | Demyelinating Diseases - metabolism | Epidermal Growth Factor - therapeutic use | Molecular Targeted Therapy | Stem Cells - metabolism | Cell Lineage - drug effects | Hypoxia - metabolism | Receptor, Epidermal Growth Factor - metabolism | Oligodendroglia - drug effects | Time Factors | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Disease Models, Animal | Animals, Newborn | Cell Survival - drug effects | Demyelinating Diseases - prevention & control | Administration, Intranasal | Infant, Premature, Diseases - drug therapy | Cell Division - drug effects | Brain Injuries - prevention & control | Oligodendroglia - pathology | Hypoxia - genetics | Regeneration - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Hypoxia - pathology | Stem Cells - drug effects | Hypoxia - physiopathology | Infant, Premature, Diseases - metabolism | Mice | Epidermal Growth Factor - pharmacology | Brain Injuries - pathology | Infant, Premature, Diseases - pathology | Brain | Medical research | Care and treatment | Infants (Premature) | Risk factors | Complications and side effects | Epidermal growth factor | Physiological aspects | Medicine, Experimental | Hypoxia | Diagnosis | Health aspects | Injuries | Brain damage | Attention Deficit Hyperactivity Disorder | Rodents | Apoptosis | Index Medicus
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3. Full Text FTY720 modulates human oligodendrocyte progenitor process extension and survival
by Miron, Veronique E and Jung, Cha Gyun and Kim, Hye Jung and Kennedy, Timothy E and Soliven, Betty and Antel, Jack P
Annals of neurology, ISSN 0364-5134, 01/2008, Volume 63, Issue 1, pp. 61 - 71
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Lysophospholipids - metabolism | Oligodendroglia - metabolism | Extracellular Signal-Regulated MAP Kinases - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Cell Movement - physiology | rho-Associated Kinases - antagonists & inhibitors | Oligodendroglia - drug effects | rho-Associated Kinases - metabolism | Propylene Glycols - therapeutic use | Receptors, Lysosphingolipid - genetics | Sphingosine - metabolism | Receptors, G-Protein-Coupled - drug effects | Receptors, Lysosphingolipid - metabolism | Cell Differentiation - physiology | Immunosuppressive Agents - pharmacology | Cell Survival - physiology | Suramin - pharmacology | RNA, Messenger - drug effects | Propylene Glycols - pharmacology | Cell Line | Cell Survival - drug effects | Fingolimod Hydrochloride | Down-Regulation - drug effects | Down-Regulation - genetics | Sphingosine - pharmacology | Cell Movement - drug effects | Sphingosine - analogs & derivatives | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Surface Extensions - drug effects | Cytoskeleton - metabolism | Receptors, Lysosphingolipid - agonists | Stem Cells - drug effects | Signal Transduction - physiology | Sphingosine - therapeutic use | Cytoskeleton - drug effects | Index Medicus
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4. Full Text Brain-Derived Neurotrophic Factor Administration Mediated Oligodendrocyte Differentiation and Myelin Formation in Subcortical Ischemic Stroke
by Ramos-Cejudo, Jaime and Gutiérrez-Fernández, María and Otero-Ortega, Laura and Rodríguez-Frutos, Berta and Fuentes, Blanca and Vallejo-Cremades, Maria Teresa and Hernanz, Teresa Navarro and Cerdán, Sebastián and Díez-Tejedor, Exuperio
Stroke (1970), ISSN 0039-2499, 01/2015, Volume 46, Issue 1, pp. 221 - 228
endothelin-1 | subcortical stroke | brain-derived neurotrophic factor | Clinical Neurology | Peripheral Vascular Disease | Neurosciences & Neurology | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Brain Ischemia - complications | Myelin Sheath - physiology | Myelin Sheath - pathology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - drug effects | Myelin Sheath - drug effects | Rats | White Matter - drug effects | Adenomatous Polyposis Coli Protein - drug effects | Diffusion Tensor Imaging | White Matter - pathology | Brain - drug effects | Stroke - pathology | Magnetic Resonance Imaging | Receptor, Platelet-Derived Growth Factor alpha - drug effects | Brain-Derived Neurotrophic Factor - pharmacology | Stroke - etiology | Animals | Oligodendroglia - drug effects | Cell Differentiation - drug effects | Brain Ischemia - pathology | Brain - pathology | Myelin Basic Protein - drug effects | Basic Helix-Loop-Helix Transcription Factors - drug effects | Index Medicus
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5. Full Text A regenerative approach to the treatment of multiple sclerosis
by Deshmukh, Vishal A and Tardif, Virginie and Lyssiotis, Costas A and Green, Chelsea C and Kerman, Bilal and Kim, Hyung Joon and Padmanabhan, Krishnan and Swoboda, Jonathan G and Ahmad, Insha and Kondo, Toru and Gage, Fred H and Theofilopoulos, Argyrios N and Lawson, Brian R and Schultz, Peter G and Lairson, Luke L
Nature (London), ISSN 0028-0836, 2013, Volume 502, Issue 7471, pp. 327 - 332
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cuprizone - therapeutic use | Oligodendroglia - metabolism | Optic Nerve - cytology | Recurrence | Antiparkinson Agents - pharmacology | Coculture Techniques | Myelin Sheath - drug effects | Receptor, Muscarinic M1 - antagonists & inhibitors | Stem Cells - cytology | Myelin Proteolipid Protein - pharmacology | Myelin Sheath - metabolism | Antiparkinson Agents - therapeutic use | Oligodendroglia - drug effects | Cuprizone - pharmacology | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Propylene Glycols - therapeutic use | Immune System - immunology | Female | Oligodendroglia - cytology | Benztropine - therapeutic use | Propylene Glycols - pharmacology | Encephalomyelitis, Autoimmune, Experimental - pathology | Myelin Sheath - pathology | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Receptor, Muscarinic M3 - metabolism | Fingolimod Hydrochloride | Rats | Receptor, Muscarinic M3 - antagonists & inhibitors | Oligodendroglia - pathology | Sphingosine - pharmacology | Regeneration - drug effects | Sphingosine - analogs & derivatives | Animals | Cell Differentiation - drug effects | Models, Biological | Immune System - drug effects | Multiple Sclerosis - pathology | Stem Cells - drug effects | Sphingosine - therapeutic use | Mice | Benztropine - pharmacology | Receptor, Muscarinic M1 - metabolism | Multiple Sclerosis - drug therapy | Benztropine | Multiple sclerosis | Myelination | Physiological aspects | Oligodendroglia | Dosage and administration | Drug therapy | Cell differentiation | Cell culture | Dopamine | Drug dosages | Rodents | Cell cycle | Index Medicus
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6. Full Text Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic
by Zhang, Zheng Gang, MD and Chopp, Michael, PhD
Lancet neurology, ISSN 1474-4422, 2009, Volume 8, Issue 5, pp. 491 - 500
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuroprotective Agents - therapeutic use | Astrocytes - drug effects | Neovascularization, Physiologic - drug effects | Recovery of Function - drug effects | Humans | Axons - drug effects | Neuronal Plasticity - drug effects | Clinical Trials as Topic | Stroke - drug therapy | Stroke - physiopathology | Brain - drug effects | Brain - blood supply | Animals | Oligodendroglia - drug effects | Neurogenesis - drug effects | Stroke (Disease) | Care and treatment | Neurons | Injuries | Stem cells | Index Medicus
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7. Full Text Argan oil-mediated attenuation of organelle dysfunction, oxidative stress and cell death induced by 7-ketocholesterol in murine oligodendrocytes 158N
by Badreddine, Asmaa and Zarrouk, Amira and Karym, El Mostafa and Debbabi, Meryam and Nury, Thomas and Meddeb, Wiem and Sghaier, Randa and Bezine, Maryem and Vejux, Anne and Martine, Lucy and Grégoire, Stéphane and Bretillon, Lionel and Prost-Camus, Emmanuelle and Durand, Philippe and Prost, Michel and Moreau, Thibault and Cherkaoui-Malki, Mustapha and Nasser, Boubker and Lizard, Gérard
International journal of molecular sciences, ISSN 1661-6596, 10/2017, Volume 18, Issue 10, p. 2220
158N murine oligodendrocytes | Mitochondria | 7-ketocholesterol | Lysosome | Peroxisome | Argan oil | Oxiapoptophagy | Extra virgin olive oil | α-tocopherol | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Lysosomes - drug effects | Cell Line | Plant Oils - pharmacology | Apoptosis - drug effects | Antioxidants - pharmacology | Mitochondria - drug effects | Peroxisomes - drug effects | Animals | Neuroprotective Agents - pharmacology | Oligodendroglia - drug effects | Ketocholesterols - toxicity | Mice | Oxidative Stress - drug effects | Lipid Peroxidation | alpha-Tocopherol - pharmacology | Brain | Oxidative stress | Membrane permeability | Lipid peroxidation | Cytotoxicity | Palmitic acid | Antioxidants | Adhesive strength | Oligodendrocytes | Cell adhesion | Polyphenols | Oxidation | Heart diseases | Neurodegenerative diseases | Phytosterols | Olive oil | Fatty acids | Cholesterol | Tyrosol | Neurological diseases | Cell death | Tocopherols | Molecular biology | Tocopherol | Cardiovascular diseases | Phagocytosis | Apoptosis | Index Medicus | Antioxidants/pharmacology | Neurons and Cognition | Oligodendroglia/drug effects | alpha-Tocopherol/pharmacology | Apoptosis/drug effects | Neurobiology | Ketocholesterols/toxicity | Neuroprotective Agents/pharmacology | Chemical Sciences | Oxidative Stress/drug effects | Life Sciences | Medicinal Chemistry | Lysosomes/drug effects | Plant Oils/pharmacology | Peroxisomes/drug effects | Mitochondria/drug effects | Food engineering | oxiapoptophagy | mitochondria | peroxisome | extra virgin olive oil | lysosome | argan oil
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