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Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2012, Volume 40, Issue 13, pp. 6135 - 6143
We report the evaluation of 20-, 18-, 16- and 14-mer phosphorothioate (PS)-modified tricycloDNA (tcDNA) gapmer antisense oligonucleotides (ASOs) in T-m, cell... 
NONHUMAN-PRIMATES | SR-BI | 2ND-GENERATION ANTISENSE OLIGONUCLEOTIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | SHOW IMPROVED POTENCY | NUCLEIC-ACID ANALOGS | MECHANISMS | 2'-MODIFIED OLIGONUCLEOTIDES | BIOLOGICAL-PROPERTIES | EXPRESSION | LNA | Index Medicus | Molecular Biology
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 198, pp. 91 - 103
We hypothesized that the co-entrapment of melanoma-associated antigens and the Toll-like receptor (TLR) ligands Poly(I:C) and CpG, known to be... 
Nanoparticles | Cancer vaccine | PLGA | Melanoma | Antigen presenting cells | Mannose receptor targeting | TLR | DENDRITIC CELLS | VACCINE DELIVERY | BIODEGRADABLE NANOPARTICLES | MICROSPHERE | CHEMISTRY, MULTIDISCIPLINARY | PLGA-BASED NANOPARTICLES | S. EQUI ANTIGENS | IMMUNOTHERAPY | PHARMACOLOGY & PHARMACY | EXPRESSION | T-LYMPHOCYTES | OVALBUMIN | Oligodeoxyribonucleotides - administration & dosage | gp100 Melanoma Antigen - chemistry | Immunoglobulin G - blood | Nanoparticles - chemistry | Ovalbumin - immunology | Poly I-C - administration & dosage | Granzymes - metabolism | Oligodeoxyribonucleotides - chemistry | Male | gp100 Melanoma Antigen - immunology | Peptides - administration & dosage | MART-1 Antigen - administration & dosage | Cancer Vaccines | Female | Ovalbumin - chemistry | Cytokines - immunology | Disease Models, Animal | Mannose - chemistry | MART-1 Antigen - chemistry | MART-1 Antigen - immunology | Peptides - chemistry | gp100 Melanoma Antigen - administration & dosage | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Mice, Transgenic | Melanoma - pathology | Poly I-C - chemistry | Animals | Ovalbumin - administration & dosage | Tumor Burden - drug effects | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Polymers - chemistry | Nanoparticles - administration & dosage | Immune response | Peptides | Analysis | Immunotherapy | Health aspects | Sugars | Tumors | Monosaccharides | Index Medicus
Journal Article
2003, ISBN 052152587X, xiv, 263
This book is a comprehensive guide to all of the mathematics, statistics and computing you will need to successfully operate DNA microarray experiments. It is... 
DNA microarrays | Oligonucleotide Array Sequence Analysis | statistics & numerical data | methods | Computational Biology | Data processing | Gene Expression Profiling | Mathematics | Statistical methods | Bioinformatics | Biology, life sciences
Book
Journal Article
Organic Letters, ISSN 1523-7060, 08/2006, Volume 8, Issue 17, pp. 3639 - 3642
We report the development of the Cu(l)-catalyzed Huisgen cycloaddition (click) reaction for the multiple postsynthetic labeling of alkyne-modified DNA. A... 
CHEMISTRY, ORGANIC | CYCLOADDITION | PROTEINS | ESCHERICHIA-COLI | DNA - chemistry | Copper - chemistry | Oligodeoxyribonucleotides - chemical synthesis | Oligodeoxyribonucleotides - chemistry | Alkynes - chemistry | Molecular Structure | Azides - chemistry | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2017, Volume 245, pp. 81 - 94
Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent... 
Peptide vaccine | Tumor microenvironment | Sunitinib base | Advanced melanoma | Polymeric micelles | CANCER-IMMUNOTHERAPY | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | NANOPARTICLES | CO-DELIVERY | CISPLATIN | IMMUNE SUPPRESSION | GROWTH | CELL CARCINOMA PATIENTS | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Oligodeoxyribonucleotides - administration & dosage | Calcium Phosphates - therapeutic use | Oligodeoxyribonucleotides - chemistry | Immunotherapy, Active | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Membrane Proteins - therapeutic use | Indoles - administration & dosage | Polymers - therapeutic use | Cancer Vaccines - therapeutic use | Pyrroles - administration & dosage | Micelles | Female | Proto-Oncogene Proteins c-akt - metabolism | Pyrroles - therapeutic use | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Oligodeoxyribonucleotides - therapeutic use | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Calcium Phosphates - chemistry | Melanoma - pathology | Antineoplastic Agents - chemistry | Membrane Proteins - administration & dosage | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Tumor Burden - drug effects | Melanoma - immunology | Calcium Phosphates - administration & dosage | Cell Line, Tumor | Pyrroles - chemistry | Indoles - therapeutic use | Polymers - chemistry | Peptide Fragments - therapeutic use | Melanoma - therapy | Indoles - chemistry | Tyrosine | Care and treatment | Analysis | Immunotherapy | Melanoma | Calcium phosphate | Vaccines | T cells | Tumors | Cancer | Index Medicus | Advanced Melanoma
Journal Article