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Science, ISSN 0036-8075, 5/2008, Volume 320, Issue 5879, pp. 1047 - 1050
Viruses shape microbial community structure and function by altering the fitness of their hosts and by promoting genetic exchange. The complexity of most... 
Metagenomics | Biofilms | Archaea | DNA | Genomics | Viruses | Genetic loci | Evolution | Genomes | Research Articles | Nucleotides | ELEMENTS | RECOMBINATION | BACTERIOPHAGES | SEQUENCES | GENOMES | MULTIDISCIPLINARY SCIENCES | LATERAL GENE-TRANSFER | REPEATS | PHAGE | PROKARYOTES | Archaea - physiology | DNA, Intergenic | Molecular Sequence Data | Archaea - virology | Recombination, Genetic | Base Sequence | Ecosystem | Thermoplasmales - genetics | Viral Proteins - physiology | Bacteriophages - genetics | Bacteria - virology | Amino Acid Sequence | Genome, Viral | Genome, Bacterial | Oligodeoxyribonucleotides | Viral Proteins - chemistry | Genome, Archaeal | Viral Proteins - genetics | Bacterial Physiological Phenomena | Thermoplasmales - physiology | Bacteria - genetics | Thermoplasmales - virology | Repetitive Sequences, Nucleic Acid | Archaeal Viruses - physiology | Archaea - genetics | Bacteriophages - physiology | Archaeal Viruses - genetics | Hydrogen-Ion Concentration | Environmental aspects | Genetic aspects | Virulence (Microbiology) | Research | Microbiology | Ecosystems | Population genetics | Virology | Bacterial | Recombination | Viral | Genetic | Archaeal | Viral Proteins/chemistry/genetics/physiology | Bacteriophages/genetics/physiology | Bacteria/genetics/virology | Natural Sciences | Thermoplasmales/genetics/physiology/virology | Archaea/genetics/physiology/virology | Repetitive Sequences | Nucleic Acid | Naturvetenskap | Intergenic | Archaeal Viruses/genetics/physiology | Genome
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2000, Volume 28, Issue 3, pp. 669 - 677
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2000, Volume 97, Issue 11, pp. 5978 - 5983
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 121, Issue 7, pp. 1097 - 1108
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 02/2012, Volume 11, Issue 2, pp. 125 - 140
Here, we discuss three RNA-based therapeutic technologies exploiting various oligonucleotides that bind to RNA by base pairing in a sequence-specific manner... 
SYSTEMIC DELIVERY | COLI-IN-VITRO | MORPHOLINO OLIGOMERS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DUCHENNE MUSCULAR-DYSTROPHY | VIRUS-INFECTIONS | MOTOR-NEURON | CELL-CULTURES | PRE-MESSENGER-RNA | RNA, Small Interfering - genetics | RNA Interference - drug effects | Oligodeoxyribonucleotides, Antisense - pharmacology | Phosphorothioate Oligonucleotides - genetics | Gene Expression - drug effects | Morpholinos - genetics | Antiviral Agents - therapeutic use | Gene Expression - genetics | Muscular Dystrophy, Duchenne - drug therapy | Alternative Splicing - genetics | Humans | Morpholinos - therapeutic use | RNA, Messenger - genetics | beta-Thalassemia - genetics | Oligodeoxyribonucleotides, Antisense - therapeutic use | beta-Thalassemia - drug therapy | Anti-Bacterial Agents - therapeutic use | Alternative Splicing - drug effects | Animals | Myotonic Dystrophy - drug therapy | Myotonic Dystrophy - genetics | Muscular Dystrophy, Duchenne - genetics | Phosphorothioate Oligonucleotides - therapeutic use | Physiological aspects | Messenger RNA | Research | Gene expression | Health aspects | Oligonucleotides | Alternative splicing | Therapeutic applications | Duchenne's muscular dystrophy | RNA-mediated interference | Clinical trials | Recovery of function | Antisense oligonucleotides
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 6, pp. 1147 - 1160
Embryos have the ability to self-regulate and regenerate normal structures after being sectioned in half. How is such a morphogenetic field established? We... 
TWISTED GASTRULATION | XENOPUS | PROTEIN | METALLOPROTEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURAL INDUCTION | RECEPTOR | NEGATIVE FEEDBACK REGULATOR | CHORDIN | CLEAVAGE | ORGANIZER | CELL BIOLOGY | Body Patterning - drug effects | Metalloendopeptidases - genetics | Organizers, Embryonic - physiology | Organizers, Embryonic - transplantation | Central Nervous System - metabolism | Bone Morphogenetic Proteins - physiology | Xenopus Proteins - genetics | Follistatin - genetics | Glycoproteins - metabolism | Metalloendopeptidases - metabolism | Oligodeoxyribonucleotides, Antisense - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Central Nervous System - embryology | Intercellular Signaling Peptides and Proteins - metabolism | Membrane Proteins - physiology | Base Sequence | Carrier Proteins - administration & dosage | Tissue Transplantation | Xenopus laevis - genetics | Phosphorylation - drug effects | Intercellular Signaling Peptides and Proteins - administration & dosage | Bone Morphogenetic Proteins - genetics | Glycoproteins - genetics | Bone Morphogenetic Protein 4 | Bone Morphogenetic Proteins - administration & dosage | Xenopus laevis - embryology | Microinjections | Bone Morphogenetic Protein 2 | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Transforming Growth Factor beta - physiology | Metalloendopeptidases - administration & dosage | Bone Morphogenetic Protein Receptors, Type I - metabolism | Glycoproteins - administration & dosage | Body Patterning - physiology | Proteins - genetics | Carrier Proteins - genetics | Animals | Transforming Growth Factor beta - genetics | Organizers, Embryonic - metabolism | Xenopus Proteins - physiology | Smad1 Protein - metabolism | Xenopus Proteins - metabolism | Mutation | Xenopus laevis - physiology | Bone Morphogenetic Protein 7 | Morphogenesis | Genetic research | Research | Genetic regulation | Ubiquitin-proteasome system | Bone morphogenetic proteins
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2004, Volume 172, Issue 3, pp. 1777 - 1785
DNA rich in nonmethylated CG motifs (CpGs) greatly facilitates induction of immune responses against coadministered Ags. CpGs are therefore among the most... 
IMMUNOSTIMULATORY CPG-OLIGODEOXYNUCLEOTIDES | CORE PARTICLES | DENDRITIC CELLS | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | TH1 IMMUNITY | IMMUNOLOGY | BACTERIAL-DNA | INNATE IMMUNITY | CUTTING EDGE | ANTIGEN | Allolevivirus - immunology | Oligodeoxyribonucleotides - administration & dosage | Dendritic Cells - immunology | Virion - genetics | Lymphocyte Activation - genetics | Oligodeoxyribonucleotides - genetics | Recombination, Genetic | Peptide Fragments - immunology | Viral Proteins - administration & dosage | Peptide Fragments - genetics | Glycoproteins - genetics | Virion - immunology | Oligodeoxyribonucleotides - immunology | Viral Proteins - genetics | Antigen Presentation - genetics | Antigen Presentation - immunology | Virion - metabolism | Glycoproteins - administration & dosage | Hepatitis B Core Antigens - genetics | Hepatitis B Core Antigens - immunology | Antigens, Viral - immunology | Glycoproteins - immunology | B-Lymphocytes - immunology | Virus Assembly - immunology | CpG Islands - genetics | T-Lymphocytes - immunology | Mice | Hepatitis B Core Antigens - administration & dosage | Dose-Response Relationship, Immunologic | Antigens, Viral - administration & dosage | Vaccines, DNA - immunology | Viral Proteins - immunology | RNA, Viral - administration & dosage | Antigens, Viral - genetics | Fibrosarcoma - immunology | Vaccines, DNA - administration & dosage | DNA Methylation | RNA, Viral - genetics | Virus Assembly - genetics | Allolevivirus - genetics | Dendritic Cells - virology | Dendritic Cells - metabolism | Liposomes - immunology | T-Lymphocytes, Cytotoxic - immunology | Thionucleotides - antagonists & inhibitors | Cytotoxicity, Immunologic - genetics | CpG Islands - immunology | T-Lymphocytes, Cytotoxic - virology | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Animals | Thionucleotides - toxicity | Fibrosarcoma - prevention & control
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2015, Volume 34, Issue 7, pp. 925 - 939
The development and function of B lymphocytes is regulated by numerous signaling pathways, some emanating from the B‐cell antigen receptor (BCR). The spleen... 
BAFF receptor | mb1‐CreERT2 | Syk | B‐cell antigen receptor | CD19 | mb1-CreER T 2 | B-cell antigen receptor | LYN | ACTIVATION | mb1-CreER(T2) | MARGINAL ZONE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-TYROSINE KINASE | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | RECOMBINASE ACTIVITY | IN-VIVO | DIFFERENTIATION | NF-KAPPA-B | ANTIGEN RECEPTOR | Antigens, CD - immunology | CD40 Antigens - antagonists & inhibitors | Cell Survival - genetics | Intracellular Signaling Peptides and Proteins - immunology | Antigens, CD19 - genetics | Antigens, CD - genetics | Phosphatidylinositol 3-Kinases - immunology | Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | ADP-ribosyl Cyclase 1 - immunology | CD40 Antigens - genetics | Interleukin-4 - genetics | Membrane Glycoproteins - immunology | B-Cell Activation Factor Receptor - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Antigens, CD19 - immunology | B-Cell Activation Factor Receptor - immunology | B-Lymphocytes - cytology | Interleukin-4 - antagonists & inhibitors | ADP-ribosyl Cyclase 1 - genetics | Signal Transduction - genetics | Cell Survival - immunology | Receptors, Antigen, B-Cell - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Antibodies - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Interleukin-4 - immunology | Animals | B-Lymphocytes - immunology | Lipopolysaccharides - pharmacology | Receptors, Antigen, B-Cell - genetics | Mice | Oligodeoxyribonucleotides - pharmacology | CD40 Antigens - immunology | Lymphocyte receptors | T cell receptors | Kinases | Immune system | mb1-CreERT2
Journal Article
Plant Physiology, ISSN 0032-0889, 12/2011, Volume 157, Issue 4, pp. 1628 - 1641
Selective inhibition of gene expression by antisense oligodeoxynucleotides (ODNs) is widely applied in gene function analyses; however, experiments with ODNs... 
Leaves | BREAKTHROUGH TECHNOLOGIES | Carotenoids | Messenger RNA | Chloroplasts | RNA | Genes | Fluorescence | Greening | Plants | Nucleic acids | CAROTENOID BIOSYNTHESIS | RNASE-H | CHLOROPHYLL-A | ARABIDOPSIS-THALIANA | INHIBITION | MESSENGER-RNA | GENE-EXPRESSION | RETICULOCYTE LYSATE | TARGET VALIDATION | OLIGONUCLEOTIDES | PLANT SCIENCES | Chloroplast Proteins - genetics | Phosphorothioate Oligonucleotides - genetics | Oligodeoxyribonucleotides - chemical synthesis | Chlorophyll Binding Proteins - metabolism | Gene Knockdown Techniques | Triticum - metabolism | Cell Nucleus - metabolism | Biological Transport | Oligodeoxyribonucleotides - genetics | Photosystem II Protein Complex - genetics | Plant Proteins - metabolism | Chloroplasts - genetics | Oxidoreductases - genetics | Tobacco - metabolism | RNA, Messenger - genetics | Gene Expression Regulation, Plant - genetics | RNA, Plant - genetics | Phosphorothioate Oligonucleotides - chemical synthesis | Chloroplasts - metabolism | Arabidopsis - metabolism | Photosystem II Protein Complex - metabolism | Arabidopsis - genetics | Triticum - genetics | Plant Proteins - genetics | Oligonucleotides, Antisense - genetics | Chlorophyll Binding Proteins - genetics | Oligonucleotides, Antisense - chemical synthesis | Plant Leaves - genetics | Plant Leaves - metabolism | Tobacco - genetics | Carotenoids - metabolism | Chloroplast Proteins - metabolism | Proteins | Oligodeoxynucleotides | Plant genetics | Physiological aspects | Genetic aspects | Research | Gene expression
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2016, Volume 62, Issue 3, pp. 462 - 471
Journal Article
Oncogene, ISSN 0950-9232, 07/2001, Volume 20, Issue 33, pp. 4457 - 4465
Defects in PTEN a tumor suppressor, have been found in cancers arising in a variety of human tissues. To elucidate the tumor-suppressive function of this gene,... 
PTEN | EGR2 | PINK1 | BPOZ | Tumor suppressor gene | ZINC FINGER PROTEIN | NERVOUS-SYSTEM | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | CELL BIOLOGY | ONCOLOGY | PROSTATE-CANCER | BTB/POZ DOMAIN | GENETICS & HEREDITY | MOLECULAR-CLONING | MUTATIONS | DIFFERENTIATION | tumor suppressor gene | HUMAN OVARIAN-CANCER | Protein Kinases - genetics | Oligodeoxyribonucleotides, Antisense - pharmacology | Humans | Repressor Proteins | Transcriptional Activation | Ovarian Neoplasms - pathology | Male | Neoplasm Proteins - pharmacology | Gene Expression Profiling | Ovarian Neoplasms - genetics | Protein Tyrosine Phosphatases - genetics | Blood Proteins - genetics | Neoplasm Proteins - genetics | Genes, Tumor Suppressor | Protein Phosphatase 1 | Expressed Sequence Tags | Phosphoprotein Phosphatases | Amino Acid Sequence | Tumor Stem Cell Assay | DNA-Binding Proteins - physiology | Tumor Cells, Cultured - metabolism | Signal Transduction - genetics | Immediate-Early Proteins - genetics | Basic-Leucine Zipper Transcription Factors | Cell Cycle Proteins - physiology | Protein Tyrosine Phosphatases - physiology | Cell Cycle - genetics | Dual Specificity Phosphatase 1 | Neoplasm Proteins - physiology | Recombinant Fusion Proteins - physiology | Molecular Sequence Data | Adaptor Proteins, Vesicular Transport | Tumor Cells, Cultured - pathology | RNA Splicing | Transfection | Early Growth Response Protein 2 | PTEN Phosphohydrolase | Cell Cycle Proteins - genetics | Adult | Female | Cell Division - genetics | Protein Structure, Tertiary | Proteins - physiology | Nerve Tissue Proteins - physiology | Phosphoric Monoester Hydrolases - genetics |