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Nature Reviews Drug Discovery, ISSN 1474-1776, 02/2012, Volume 11, Issue 2, pp. 125 - 140
Here, we discuss three RNA-based therapeutic technologies exploiting various oligonucleotides that bind to RNA by base pairing in a sequence-specific manner... 
SYSTEMIC DELIVERY | COLI-IN-VITRO | MORPHOLINO OLIGOMERS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DUCHENNE MUSCULAR-DYSTROPHY | VIRUS-INFECTIONS | MOTOR-NEURON | CELL-CULTURES | PRE-MESSENGER-RNA | RNA, Small Interfering - genetics | RNA Interference - drug effects | Oligodeoxyribonucleotides, Antisense - pharmacology | Phosphorothioate Oligonucleotides - genetics | Gene Expression - drug effects | Morpholinos - genetics | Antiviral Agents - therapeutic use | Gene Expression - genetics | Muscular Dystrophy, Duchenne - drug therapy | Alternative Splicing - genetics | Humans | Morpholinos - therapeutic use | RNA, Messenger - genetics | beta-Thalassemia - genetics | Oligodeoxyribonucleotides, Antisense - therapeutic use | beta-Thalassemia - drug therapy | Anti-Bacterial Agents - therapeutic use | Alternative Splicing - drug effects | Animals | Myotonic Dystrophy - drug therapy | Myotonic Dystrophy - genetics | Muscular Dystrophy, Duchenne - genetics | Phosphorothioate Oligonucleotides - therapeutic use | Physiological aspects | Messenger RNA | Research | Gene expression | Health aspects | Oligonucleotides | Alternative splicing | Therapeutic applications | Duchenne's muscular dystrophy | RNA-mediated interference | Clinical trials | Recovery of function | Antisense oligonucleotides
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2017, Volume 245, pp. 81 - 94
Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent... 
Peptide vaccine | Tumor microenvironment | Sunitinib base | Advanced melanoma | Polymeric micelles | CANCER-IMMUNOTHERAPY | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | NANOPARTICLES | CO-DELIVERY | CISPLATIN | IMMUNE SUPPRESSION | GROWTH | CELL CARCINOMA PATIENTS | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Oligodeoxyribonucleotides - administration & dosage | Calcium Phosphates - therapeutic use | Oligodeoxyribonucleotides - chemistry | Immunotherapy, Active | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Membrane Proteins - therapeutic use | Indoles - administration & dosage | Polymers - therapeutic use | Cancer Vaccines - therapeutic use | Pyrroles - administration & dosage | Micelles | Female | Proto-Oncogene Proteins c-akt - metabolism | Pyrroles - therapeutic use | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Oligodeoxyribonucleotides - therapeutic use | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Calcium Phosphates - chemistry | Melanoma - pathology | Antineoplastic Agents - chemistry | Membrane Proteins - administration & dosage | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Tumor Burden - drug effects | Melanoma - immunology | Calcium Phosphates - administration & dosage | Cell Line, Tumor | Pyrroles - chemistry | Indoles - therapeutic use | Polymers - chemistry | Peptide Fragments - therapeutic use | Melanoma - therapy | Indoles - chemistry | Tyrosine | Care and treatment | Analysis | Immunotherapy | Melanoma | Calcium phosphate | Vaccines | T cells | Tumors | Cancer | Advanced Melanoma
Journal Article
Neuron, ISSN 0896-6273, 06/2012, Volume 74, Issue 6, pp. 1031 - 1044
Journal Article
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 967 - 970
Journal Article