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Current opinion in microbiology, ISSN 1369-5274, 2016, Volume 33, pp. 47 - 55
Pathology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Antiviral Agents - pharmacology | Oligodeoxyribonucleotides, Antisense - pharmacology | Viruses - genetics | Bacterial Infections - drug therapy | Bacteria - drug effects | Parasitic Diseases - drug therapy | Drug Discovery - methods | Viruses - drug effects | Oligoribonucleotides, Antisense - pharmacology | Bacteria - genetics | Parasites - genetics | Parasites - drug effects | Animals | Virus Diseases - drug therapy | Phosphorothioate Oligonucleotides - pharmacology | Anti-Bacterial Agents - pharmacology | Antiviral agents | Therapeutics | Drug resistance | Hepatitis C virus | Hepatitis C | Homeopathy | Materia medica and therapeutics | Index Medicus
Journal Article
Clinical pharmacokinetics, ISSN 0312-5963, 2/2015, Volume 54, Issue 2, pp. 133 - 146
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Apolipoproteins B - antagonists & inhibitors | Oligonucleotides - chemistry | Oligodeoxyribonucleotides, Antisense - pharmacology | Humans | Models, Molecular | Anticholesteremic Agents - chemistry | Clinical Trials as Topic | Oligonucleotides - pharmacokinetics | Anticholesteremic Agents - pharmacokinetics | Animals | Oligonucleotides - pharmacology | Base Sequence | Hyperlipoproteinemia Type I - drug therapy | Hyperlipoproteinemia Type I - metabolism | Anticholesteremic Agents - pharmacology | Oligodeoxyribonucleotides, Antisense - pharmacokinetics
Journal Article
Nature reviews. Drug discovery, ISSN 1474-1776, 02/2012, Volume 11, Issue 2, pp. 125 - 140
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | RNA, Small Interfering - genetics | RNA Interference - drug effects | Oligodeoxyribonucleotides, Antisense - pharmacology | Phosphorothioate Oligonucleotides - genetics | Gene Expression - drug effects | Morpholinos - genetics | Antiviral Agents - therapeutic use | Gene Expression - genetics | Muscular Dystrophy, Duchenne - drug therapy | Alternative Splicing - genetics | Humans | Morpholinos - therapeutic use | RNA, Messenger - genetics | beta-Thalassemia - genetics | Oligodeoxyribonucleotides, Antisense - therapeutic use | beta-Thalassemia - drug therapy | Anti-Bacterial Agents - therapeutic use | Alternative Splicing - drug effects | Animals | Myotonic Dystrophy - drug therapy | Myotonic Dystrophy - genetics | Muscular Dystrophy, Duchenne - genetics | Phosphorothioate Oligonucleotides - therapeutic use | Physiological aspects | Messenger RNA | Research | Gene expression | Health aspects | Oligonucleotides | Alternative splicing | Therapeutic applications | Duchenne's muscular dystrophy | RNA-mediated interference | Clinical trials | Recovery of function | Antisense oligonucleotides | Index Medicus
Journal Article
Current atherosclerosis reports, ISSN 1523-3804, 8/2019, Volume 21, Issue 8, pp. 1 - 7
Apolipoprotein B | Apolipoprotein(a) | Medicine & Public Health | Mipomersen | Angiology | Cardiology | AKCEA-APO(a)-L Rx | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Apolipoproteins B - antagonists & inhibitors | Cholesterol Ester Transfer Proteins - antagonists & inhibitors | Oligodeoxyribonucleotides, Antisense - pharmacology | Oligonucleotides - therapeutic use | Antibodies, Monoclonal - pharmacology | Humans | Apoprotein(a) - antagonists & inhibitors | Oligodeoxyribonucleotides, Antisense - therapeutic use | Antibodies, Monoclonal - therapeutic use | Oligonucleotides - pharmacology | Proprotein Convertase 9 - antagonists & inhibitors | RNA Interference | Hyperlipoproteinemias - drug therapy | Atherosclerosis - prevention & control | Index Medicus
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 2014, Volume 350, Issue 1, pp. 46 - 55
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | RNA Splicing - drug effects | Oligodeoxyribonucleotides, Antisense - pharmacology | Oligodeoxyribonucleotides, Antisense - administration & dosage | Oligonucleotides - therapeutic use | Injections, Intraventricular | Macaca fascicularis | Oligodeoxyribonucleotides, Antisense - therapeutic use | Male | Oligonucleotides - pharmacokinetics | Mice, Knockout | Brain - drug effects | Brain - metabolism | Muscular Atrophy, Spinal - genetics | Animals | Oligonucleotides - pharmacology | Survival of Motor Neuron 2 Protein - genetics | Female | Muscular Atrophy, Spinal - drug therapy | Mice | Oligonucleotides - administration & dosage | Infusions, Intraventricular | Oligodeoxyribonucleotides, Antisense - pharmacokinetics
Journal Article
Journal of lipid research, ISSN 0022-2275, 2018, Volume 59, Issue 12, pp. 2397 - 2402
ApoB antisense treatment | Fractional clearance rate | Production rate | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Oligodeoxyribonucleotides, Antisense - pharmacology | Humans | Middle Aged | Apolipoprotein B-100 - blood | Male | Oligonucleotides - pharmacology | Mass Spectrometry | Lipid Metabolism - drug effects | Chromatography, Liquid | Adult | Cholesterol, LDL - blood | Female | Lipoprotein(a) - blood | Index Medicus | fractional clearance rate | Patient-Oriented and Epidemiological Research | production rate | apoB antisense treatment
Journal Article
Journal of antimicrobial chemotherapy, ISSN 0305-7453, 2017, Volume 72, Issue 1, pp. 137 - 144
Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biofilms - drug effects | Microbial Sensitivity Tests | Peptide Nucleic Acids - pharmacology | Bacterial Proteins - antagonists & inhibitors | Oligodeoxyribonucleotides, Antisense - pharmacology | Haemophilus influenzae - drug effects | Haemophilus influenzae - physiology | Drug Resistance, Bacterial | Acyl Carrier Protein - antagonists & inhibitors | Anti-Bacterial Agents - pharmacology | Serial Passage | Index Medicus | Original Research
Journal Article
Molecular therapy, ISSN 1525-0016, 02/2012, Volume 20, Issue 2, pp. 376 - 381
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Proprotein Convertases - antagonists & inhibitors | Oligonucleotides - chemistry | Oligodeoxyribonucleotides, Antisense - pharmacology | Oligodeoxyribonucleotides, Antisense - administration & dosage | Humans | Proprotein Convertases - metabolism | Macaca fascicularis | Male | Proprotein Convertases - genetics | Animals | Injections, Subcutaneous | Serine Endopeptidases - genetics | Cholesterol, LDL - metabolism | Serine Endopeptidases - metabolism | Proprotein Convertase 9 | Index Medicus | Original
Journal Article
Clinical cancer research, ISSN 1078-0432, 09/2006, Volume 12, Issue 17, pp. 5231 - 5241
XIAP | MBO | preclinical | cancer therapeutic | antisense | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Oligodeoxyribonucleotides, Antisense - pharmacology | Apoptosis - drug effects | Humans | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Structure-Activity Relationship | Dose-Response Relationship, Drug | Taxoids - therapeutic use | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Oligonucleotides - pharmacology | Reverse Transcriptase Polymerase Chain Reaction - methods | Sensitivity and Specificity | Antineoplastic Agents - pharmacology | Disease Models, Animal | RNA, Messenger - drug effects | RNA, Messenger - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Mice | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 02/2011, Volume 10, Issue 2, pp. 221 - 232
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Oligodeoxyribonucleotides, Antisense - pharmacology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | HCT116 Cells | Humans | Caspase 3 - metabolism | Down-Regulation - drug effects | Cell Division - drug effects | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Mice | Gene Expression Regulation, Neoplastic - drug effects | HeLa Cells | Neoplasms - physiopathology | Cell Cycle - drug effects | Antisense oligonucleotides | Index Medicus
Journal Article