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Journal of Liquid Chromatography & Related Technologies, ISSN 1082-6076, 04/2015, Volume 38, Issue 6, pp. 692 - 697
A method was developed for the determination of omeprazole, 5-hydroxy-omeprazole, and omeprazole-sulphone in human plasma. The mobile phase with 0.1% formic... 
pharmacokinetics | omeprazole | 5-hydroxy-omeprazole | plasma | omeprazole-sulphone | LCMS | CHEMISTRY, ANALYTICAL | RAPID-DETERMINATION | QUANTIFICATION | BIOCHEMICAL RESEARCH METHODS | CYP2C19 PHENOTYPE | PROTON PUMP INHIBITORS | MAIN METABOLITES | URINE | DRUGS | PROBE | HPLC | Human | Mass spectrometers | Liquids | Spectrometry | Mathematical analysis | Formic acid | Regression | Calibration
Journal Article
Chinese Journal of Antibiotics, ISSN 1001-8689, 2012, Volume 37, Issue 10, pp. 773 - 775
Journal Article
Journal of the Brazilian Chemical Society, ISSN 0103-5053, 2007, Volume 18, Issue 4, pp. 733 - 740
A simple HPLC-DAD method using a reverse phase column and isocratic elution for the simultaneous determination of omeprazole (OME), 5-hydroxyomeprazole (HOME)... 
Omeprazole | HPLC-DAD | CYP2C19 | CYP3A4 | Phenotyping | POPULATION | omeprazole | METABOLITES | GENOTYPE | HYDROXYLATION | phenotyping | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | S-MEPHENYTOIN | COCKTAIL | LIQUID-CHROMATOGRAPHY | ENZYMES | URINE
Journal Article
Journal Article
Chinese Pharmacological Bulletin, ISSN 1001-1978, 2002, Volume 18, Issue 3, pp. 342 - 344
Journal Article
Journal of chromatography, 12/1983, Volume 278, Issue 2, p. 311
Omeprazole, a substituted benzimidazole which suppresses gastric acid secretion, and its sulphone and sulphide metabolites were simultaneously measured in... 
Omeprazole | Chromatography, High Pressure Liquid - methods | Humans | Benzimidazoles - urine | Adult | Male | Kinetics | Tablets, Enteric-Coated | Benzimidazoles - analysis | Benzimidazoles - blood
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 06/1994, Volume 37, Issue 6, pp. 597 - 604
1. The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the secondary metabolic pathways and identify the cytochrome... 
Omeprazole | Kinetics | CYP isoforms | Human microsomal metabolism | OXIDATION | INVITRO | ACID-SECRETION | HYDROXYLATION | OMEPRAZOLE | C-14 OMEPRAZOLE | S-MEPHENYTOIN | KINETICS | MICROSOMES | PRODUCT | HUMAN MICROSOMAL METABOLISM | PHARMACOLOGY & PHARMACY | CYP ISOFORMS | INHIBITOR | RANITIDINE
Journal Article
Journal Article
Xenobiotica, ISSN 0049-8254, 10/2018, Volume 48, Issue 10, pp. 1006 - 1020
The human mass balance of [ 14  C]Z-215, a novel proton pump inhibitor, was characterised in six healthy male volunteers following single oral administration... 
Absorption | cytochrome P450 3A4 | E3710 | elimination | metabolic profile | drug metabolism | CLARITHROMYCIN | LANSOPRAZOLE | RABEPRAZOLE | GASTRIC-ACID-SECRETION | GENOTYPE | OMEPRAZOLE | CYP2C19 | ARTICLE | PHARMACOKINETICS | PHARMACOLOGY & PHARMACY | VONOPRAZAN | TOXICOLOGY
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/1993, Volume 36, Issue 6, pp. 521 - 530
1 The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the metabolic pathways and identify the cytochrome P450 (CYP)... 
omeprazole | human microsomal metabolism | kinetics | CYP isoforms | OXIDATION | MEPHENYTOIN | POOR METABOLIZERS | INVITRO | ACID-SECRETION | OMEPRAZOLE | C-14 OMEPRAZOLE | HYDROXYLATION POLYMORPHISM | KINETICS | MICROSOMES | HUMAN MICROSOMAL METABOLISM | PHARMACOLOGY & PHARMACY | CYP ISOFORMS | INHIBITOR | RANITIDINE
Journal Article
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