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Cancer Cell, ISSN 1535-6108, 11/2013, Volume 24, Issue 5, pp. 603 - 616
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 340 - 347
Neurofibromatosis type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve... 
MEDICINE, RESEARCH & EXPERIMENTAL | SIGNALING PATHWAYS | PLEXIFORM NEUROFIBROMAS | GENOMIC ANALYSES | THERAPEUTIC TARGET | NF1 | SCHWANN-CELLS | HYPERACTIVE RAS | CANCER | NERVE SHEATH TUMORS | PREVIOUSLY TREATED PATIENTS | Neoplasm Transplantation | Mitogen-Activated Protein Kinase Kinases - genetics | Diphenylamine - pharmacology | Humans | Child, Preschool | Male | Transplantation, Heterologous | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Oncogene Protein p21(ras) - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Peripheral Nervous System Neoplasms - enzymology | Mice, Mutant Strains | Female | Benzamides - pharmacology | Neurofibromatosis 1 - genetics | Peripheral Nervous System Neoplasms - pathology | raf Kinases - genetics | Child | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Peripheral Nervous System Neoplasms - drug therapy | Transcriptome - drug effects | Transcriptome - genetics | Xenograft Model Antitumor Assays | Neurofibromatosis 1 - enzymology | Neurofibromatosis 1 - pathology | Animals | Neurofibromatosis 1 - drug therapy | Mice | Peripheral Nervous System Neoplasms - genetics | Oncogene Protein p21(ras) - genetics | Physiological aspects | Causes of | Neural stimulation | Enzyme inhibitors | Properties | Neurofibromatosis
Journal Article
Nature, ISSN 0028-0836, 2015, Volume 521, Issue 7550, pp. 43 - 37
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 13, pp. 4910 - 4915
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7421, pp. 547 - 551
Mitochondrial respiratory function is frequently impaired in human cancers(1-4). However, the mechanisms by which mitochondrial dysfunction contributes to... 
OXIDATIVE STRESS | INVASION | TISSUE OVERGROWTH | PATHWAY | REGENERATION | MULTIDISCIPLINARY SCIENCES | GROWTH | MIDGUT | STEM-CELL PROLIFERATION | COOPERATION | CANCER | Neoplasms - metabolism | Up-Regulation | Compound Eye, Arthropod - ultrastructure | Reactive Oxygen Species - metabolism | Oxidative Stress | JNK Mitogen-Activated Protein Kinases - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Wnt1 Protein - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Oncogene Protein p21(ras) - metabolism | Drosophila melanogaster - metabolism | Compound Eye, Arthropod - growth & development | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Compound Eye, Arthropod - pathology | Signal Transduction | Drosophila melanogaster - cytology | Mitochondria - metabolism | Imaginal Discs - pathology | Mitochondria - pathology | Clone Cells - metabolism | Disease Progression | Transcription Factors - metabolism | Animals | Clone Cells - pathology | Cell Transformation, Neoplastic | Drosophila melanogaster - enzymology | Imaginal Discs - metabolism | Neoplasms - pathology | Oncogene Protein p21(ras) - genetics | Cell interaction | Drosophila | Development and progression | Genetic aspects | Mitochondrial DNA | Observations | Properties | Tumors | Oxidative stress | Insects | Rodents | Cloning | Cell cycle | Respiratory system | Cancer | Apoptosis | Defects
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7524, pp. 628 - 632
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 21, pp. 6625 - 6630
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 07/2013, Volume 98, Issue 7, pp. E1266 - E1271
Journal Article